Click here to switch to the map view.

The map label for this gene is gpsA [H]

Identifier: 187927321

GI number: 187927321

Start: 229731

End: 230762

Strand: Direct

Name: gpsA [H]

Synonym: Rpic_0213

Alternate gene names: 187927321

Gene position: 229731-230762 (Clockwise)

Preceding gene: 187927320

Following gene: 187927324

Centisome position: 5.83

GC content: 67.25

Gene sequence:

>1032_bases
ATGTTGAACACGCGCATGCGAATTTCCGTTTTGGGTGCCGGTGCCTGGGGCACTGCCCTGGCCAGCCACGCCGCGCAATC
GCACGACGTCATGCTGTGGGGGCGTGACGCGAACCTCGTCGCGCAGATGGCCGCCACACACATCAACGCGCCGTATTTGC
CGGGCATGACGCTGCGGGCGTCGTTGCATTTTTCTGCTGATCTGCAAGCCGCGCTCGACCATGCGGCGGGCGACGACGCG
CTCGCCGTCATCGCTTCACCTGTCGCCGGGCTGGCTGACCTGACCCGCACGATTGCCGCGCACGGCGGCGTGCGCAACGT
GATCTGGCTGTGCAAGGGGTTCGACCCCGAAACCAGCGCACTGCCGCACGCCATCGTCGCCGATGTGCTGAAGGTGTCTG
GCCGTACCGACCTCGCTGTCGGGGTGCTGTCGGGGCCGAGTTTCGCCAAGGAAGTCGCGCAGGGTTTGCCGTGCGCCATG
ACGGTCGCCTCGACCAGCGATGCGCTGTGCAAGCTCACGCAGCGCGGTTTTCACCATCACGCGATGCGCGTGTATGCAAG
CGATGACCTCGTCGGCGTGGAAGTGGGCGGTGCCGTTAAGAACGTGCTCGCCATTGCGACAGGCGCCGCCGACGGCCTGG
GCCTCGGGCTGAACGCGCGCGCCGCACTGGTCACGCGCGGGCTGGCCGAGATGACGCGCCTGGGGTTGGCGCTCGGTGGT
CGGCTGGAAACATTCATGGGGCTGACTGGCGTGGGCGATCTGCTGCTGACCGCCACCGGCGATCTGTCACGCAACCGCAC
GGTCGGGATGCAGCTTGCGCAGGGCCGCACGCTCGACGACATCCTGCACAGCCTCGGTCACGTCGCCGAAGGCGTGCGTT
GTGCGCGTGCCGTTGCGGCGCTCGCGCGCGCCAAGGGCGTGGACATGCCGATCACCTTTACCGTCTGCGAAGTCCTGTTC
GAAGGGCTTCCTGCTGCGAAGGCGGTCGAGCGTCTGCTGCAGCGCGACGCCAAATCCGAATCGGCACGCTAG

Upstream 100 bases:

>100_bases
CCCACTAAGTACGAGGCGCACTGCGCCAGAGGCCCGCGCCAGCCGCACGCTTGCGCGGGCTTTTTTTTGCCCGACCTGTT
GCTCGACCTTTGCCTGACCG

Downstream 100 bases:

>100_bases
TCACGCCGCAATCAAGGGGCGCGTCAGGCTCAGGCGCCGCCCGCGAACCCGTTCTGCCGCCACGCTTCGAACACCACCAC
TGCCACGGTGTTCGATAGAT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MLNTRMRISVLGAGAWGTALASHAAQSHDVMLWGRDANLVAQMAATHINAPYLPGMTLRASLHFSADLQAALDHAAGDDA
LAVIASPVAGLADLTRTIAAHGGVRNVIWLCKGFDPETSALPHAIVADVLKVSGRTDLAVGVLSGPSFAKEVAQGLPCAM
TVASTSDALCKLTQRGFHHHAMRVYASDDLVGVEVGGAVKNVLAIATGAADGLGLGLNARAALVTRGLAEMTRLGLALGG
RLETFMGLTGVGDLLLTATGDLSRNRTVGMQLAQGRTLDDILHSLGHVAEGVRCARAVAALARAKGVDMPITFTVCEVLF
EGLPAAKAVERLLQRDAKSESAR

Sequences:

>Translated_343_residues
MLNTRMRISVLGAGAWGTALASHAAQSHDVMLWGRDANLVAQMAATHINAPYLPGMTLRASLHFSADLQAALDHAAGDDA
LAVIASPVAGLADLTRTIAAHGGVRNVIWLCKGFDPETSALPHAIVADVLKVSGRTDLAVGVLSGPSFAKEVAQGLPCAM
TVASTSDALCKLTQRGFHHHAMRVYASDDLVGVEVGGAVKNVLAIATGAADGLGLGLNARAALVTRGLAEMTRLGLALGG
RLETFMGLTGVGDLLLTATGDLSRNRTVGMQLAQGRTLDDILHSLGHVAEGVRCARAVAALARAKGVDMPITFTVCEVLF
EGLPAAKAVERLLQRDAKSESAR
>Mature_343_residues
MLNTRMRISVLGAGAWGTALASHAAQSHDVMLWGRDANLVAQMAATHINAPYLPGMTLRASLHFSADLQAALDHAAGDDA
LAVIASPVAGLADLTRTIAAHGGVRNVIWLCKGFDPETSALPHAIVADVLKVSGRTDLAVGVLSGPSFAKEVAQGLPCAM
TVASTSDALCKLTQRGFHHHAMRVYASDDLVGVEVGGAVKNVLAIATGAADGLGLGLNARAALVTRGLAEMTRLGLALGG
RLETFMGLTGVGDLLLTATGDLSRNRTVGMQLAQGRTLDDILHSLGHVAEGVRCARAVAALARAKGVDMPITFTVCEVLF
EGLPAAKAVERLLQRDAKSESAR

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=348, Percent_Identity=27.5862068965517, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI24307999, Length=346, Percent_Identity=26.3005780346821, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1790037, Length=342, Percent_Identity=42.3976608187134, Blast_Score=238, Evalue=4e-64,
Organism=Caenorhabditis elegans, GI32564399, Length=328, Percent_Identity=28.3536585365854, Blast_Score=94, Evalue=9e-20,
Organism=Caenorhabditis elegans, GI193210136, Length=337, Percent_Identity=27.893175074184, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=337, Percent_Identity=27.893175074184, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17507425, Length=291, Percent_Identity=26.4604810996564, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193210134, Length=322, Percent_Identity=25.4658385093168, Blast_Score=81, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6324513, Length=368, Percent_Identity=28.804347826087, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6320181, Length=364, Percent_Identity=27.1978021978022, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI22026922, Length=358, Percent_Identity=24.3016759776536, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI17136202, Length=328, Percent_Identity=27.7439024390244, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136204, Length=328, Percent_Identity=27.7439024390244, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17136200, Length=328, Percent_Identity=27.7439024390244, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI281362270, Length=307, Percent_Identity=27.3615635179153, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI45551945, Length=307, Percent_Identity=27.3615635179153, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648969, Length=270, Percent_Identity=28.5185185185185, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 35440; Mature: 35440

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTRMRISVLGAGAWGTALASHAAQSHDVMLWGRDANLVAQMAATHINAPYLPGMTLRA
CCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCEEEE
SLHFSADLQAALDHAAGDDALAVIASPVAGLADLTRTIAAHGGVRNVIWLCKGFDPETSA
EEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCC
LPHAIVADVLKVSGRTDLAVGVLSGPSFAKEVAQGLPCAMTVASTSDALCKLTQRGFHHH
CCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHCHHHH
AMRVYASDDLVGVEVGGAVKNVLAIATGAADGLGLGLNARAALVTRGLAEMTRLGLALGG
HEEEEECCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
RLETFMGLTGVGDLLLTATGDLSRNRTVGMQLAQGRTLDDILHSLGHVAEGVRCARAVAA
HHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LARAKGVDMPITFTVCEVLFEGLPAAKAVERLLQRDAKSESAR
HHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MLNTRMRISVLGAGAWGTALASHAAQSHDVMLWGRDANLVAQMAATHINAPYLPGMTLRA
CCCCEEEEEEEECCHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHCCCCCCCCCEEEE
SLHFSADLQAALDHAAGDDALAVIASPVAGLADLTRTIAAHGGVRNVIWLCKGFDPETSA
EEEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCCCC
LPHAIVADVLKVSGRTDLAVGVLSGPSFAKEVAQGLPCAMTVASTSDALCKLTQRGFHHH
CCHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHCHHHH
AMRVYASDDLVGVEVGGAVKNVLAIATGAADGLGLGLNARAALVTRGLAEMTRLGLALGG
HEEEEECCCEEEEECCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
RLETFMGLTGVGDLLLTATGDLSRNRTVGMQLAQGRTLDDILHSLGHVAEGVRCARAVAA
HHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LARAKGVDMPITFTVCEVLFEGLPAAKAVERLLQRDAKSESAR
HHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]