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The map label for this gene is kdgR [H]

Identifier: 187927264

GI number: 187927264

Start: 173909

End: 174817

Strand: Reverse

Name: kdgR [H]

Synonym: Rpic_0156

Alternate gene names: 187927264

Gene position: 174817-173909 (Counterclockwise)

Preceding gene: 187927270

Following gene: 187927262

Centisome position: 4.43

GC content: 69.64

Gene sequence:

>909_bases
ATGCCCATCGACGCCCCCCTGCCCCCGGTTACATCGCCCCACGAACTGGCCGCAGAAGACGCCACGCCTGAACGCACCAG
CGCCGGCATCCAGTCCGCTGAGATCGCGTTGAGCGTGCTTTCGGCGATGGCGCATGCCGGTGGCGCACACGCCGTCTCCG
AACTCGGGCGGCAGTTGGGCATGCCGCGCGCGAAGGTGCACCGTTACCTGGTGTCGCTGGAACGCATGGGTTTTGTCGAG
CAGGACCCCGCTTCCGCCCGCTACCGGCTGGGGGCGCAGGCGTTGCAGGTGGGGCTGTCGGCGCTGTCCGACGTGGATTT
CGTGCGCGAGGGCAGCAACCTGCTCCCCAAGCTGGCCGAGCGGCTGAACGAAAGCGTGTTTCTGTCGATCTGGACCGCGC
GCGGCCCGGTCATCGTGCGCTGGGAAGACAGCGGCAGGCCGGTGGCGGTCAATGTGAGGGTGGGGTCTGTCATGCCCCTG
CTGAATTCGGCCACGGGTCAGGCATGCGCGGCGTGGGTGCCCGAAATCCAGATCGTCTCGCTCATCGACCGTGAATTGCG
CGGGCCGGGTGCCGGCAAGGCGGGCCTGACCGACTGGCTGAACTGCCGCGCGCGCTGGCAGGCGGTGCGGCAGGAGGGCG
TGGCGCGCATCGGCGGGACATTGGTGCACGGCATCGATTCGGTGGCCGTGCCGGTGCTCGATTCACAAGGCAAGCTGGCC
GGGGCGATCACGGCGCTGGGCTTGTCCAGCGTGTTCGATTCGAGCCTGGAAGGGCCCGCCGCGCGGCTATTGCGCGAGGC
CGGGCGGACGCTATCCCTTCGTCTGGGGTATCACGGGCAGGCGCTGATGGCCGGTGCCGCTGCGCCAAAGCGGGGGCGCC
GTCCGCGGACGACGCCCGAATCCGCGTAG

Upstream 100 bases:

>100_bases
GTCTCCGGGTTCGAGGTCTTTTCCAGCGCGCAGGGCCGCCGCGCCGTTTGTATCTTTTTACGTAACGCGTATCTTATAAA
GCGACACTCGAGACTTCAAG

Downstream 100 bases:

>100_bases
GGCAAGGCTTACGCCTGCGTGCCCGGCGCGACAACTTCCTGGTCGATCGCCCCGAAAATCGACACGCCGTTGGCGTCGAA
CATCTCGATCTTCACGGTGT

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MPIDAPLPPVTSPHELAAEDATPERTSAGIQSAEIALSVLSAMAHAGGAHAVSELGRQLGMPRAKVHRYLVSLERMGFVE
QDPASARYRLGAQALQVGLSALSDVDFVREGSNLLPKLAERLNESVFLSIWTARGPVIVRWEDSGRPVAVNVRVGSVMPL
LNSATGQACAAWVPEIQIVSLIDRELRGPGAGKAGLTDWLNCRARWQAVRQEGVARIGGTLVHGIDSVAVPVLDSQGKLA
GAITALGLSSVFDSSLEGPAARLLREAGRTLSLRLGYHGQALMAGAAAPKRGRRPRTTPESA

Sequences:

>Translated_302_residues
MPIDAPLPPVTSPHELAAEDATPERTSAGIQSAEIALSVLSAMAHAGGAHAVSELGRQLGMPRAKVHRYLVSLERMGFVE
QDPASARYRLGAQALQVGLSALSDVDFVREGSNLLPKLAERLNESVFLSIWTARGPVIVRWEDSGRPVAVNVRVGSVMPL
LNSATGQACAAWVPEIQIVSLIDRELRGPGAGKAGLTDWLNCRARWQAVRQEGVARIGGTLVHGIDSVAVPVLDSQGKLA
GAITALGLSSVFDSSLEGPAARLLREAGRTLSLRLGYHGQALMAGAAAPKRGRRPRTTPESA
>Mature_301_residues
PIDAPLPPVTSPHELAAEDATPERTSAGIQSAEIALSVLSAMAHAGGAHAVSELGRQLGMPRAKVHRYLVSLERMGFVEQ
DPASARYRLGAQALQVGLSALSDVDFVREGSNLLPKLAERLNESVFLSIWTARGPVIVRWEDSGRPVAVNVRVGSVMPLL
NSATGQACAAWVPEIQIVSLIDRELRGPGAGKAGLTDWLNCRARWQAVRQEGVARIGGTLVHGIDSVAVPVLDSQGKLAG
AITALGLSSVFDSSLEGPAARLLREAGRTLSLRLGYHGQALMAGAAAPKRGRRPRTTPESA

Specific function: Transcriptional repressor of genes involved in pectinolysis and in pectinase secretion. Controls all the genes involved in pectin catabolism, including the pel genes encoding pectate lyases, kdgT which encodes the 2-keto-3-deoxygluconate transport system

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=248, Percent_Identity=23.7903225806452, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788131, Length=233, Percent_Identity=24.0343347639485, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87082359, Length=251, Percent_Identity=23.9043824701195, Blast_Score=65, Evalue=7e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 31828; Mature: 31697

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIDAPLPPVTSPHELAAEDATPERTSAGIQSAEIALSVLSAMAHAGGAHAVSELGRQLG
CCCCCCCCCCCCCHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
MPRAKVHRYLVSLERMGFVEQDPASARYRLGAQALQVGLSALSDVDFVREGSNLLPKLAE
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RLNESVFLSIWTARGPVIVRWEDSGRPVAVNVRVGSVMPLLNSATGQACAAWVPEIQIVS
HCCCCEEEEEEECCCCEEEEECCCCCEEEEEEECCCHHHHHHCCCCCHHHHHCCCHHHHH
LIDRELRGPGAGKAGLTDWLNCRARWQAVRQEGVARIGGTLVHGIDSVAVPVLDSQGKLA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHH
GAITALGLSSVFDSSLEGPAARLLREAGRTLSLRLGYHGQALMAGAAAPKRGRRPRTTPE
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCCCCCCCC
SA
CC
>Mature Secondary Structure 
PIDAPLPPVTSPHELAAEDATPERTSAGIQSAEIALSVLSAMAHAGGAHAVSELGRQLG
CCCCCCCCCCCCHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHC
MPRAKVHRYLVSLERMGFVEQDPASARYRLGAQALQVGLSALSDVDFVREGSNLLPKLAE
CCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
RLNESVFLSIWTARGPVIVRWEDSGRPVAVNVRVGSVMPLLNSATGQACAAWVPEIQIVS
HCCCCEEEEEEECCCCEEEEECCCCCEEEEEEECCCHHHHHHCCCCCHHHHHCCCHHHHH
LIDRELRGPGAGKAGLTDWLNCRARWQAVRQEGVARIGGTLVHGIDSVAVPVLDSQGKLA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHH
GAITALGLSSVFDSSLEGPAARLLREAGRTLSLRLGYHGQALMAGAAAPKRGRRPRTTPE
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCCCCCCCC
SA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1840643; 1545709 [H]