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The map label for this gene is yngE [H]

Identifier: 187927214

GI number: 187927214

Start: 123421

End: 125040

Strand: Direct

Name: yngE [H]

Synonym: Rpic_0106

Alternate gene names: 187927214

Gene position: 123421-125040 (Clockwise)

Preceding gene: 187927213

Following gene: 187927215

Centisome position: 3.13

GC content: 66.42

Gene sequence:

>1620_bases
ATGCCGGCGCTTGAATCGCGCATCGTGCCGCAGAGCGACGCGTATCGGCAGAACCATGCCGCGCTCACGGAACTCGTCGG
CCGGTTGCGCACGTTGGAAGATCGCACACGCGACAAGTCCGAAGCCTCGCGCGCCCGCTTCGAGCAGCGCGGTCAACTCC
TGCCGCGCGACCGGCTTGGCCGCCTGCTCGACGCCGGCGCGCCGTTTCTTGAGCTATCCACGCTGGCGGGCTTTTGCCTC
GACCACGCAGACCCGGCGCGCTCGATTCCTGGCGGCGGCTTCATCGCGGGCATCGGCTGGGTGAGCGGTGTGCGCGCGAT
GATCATTGTCGACGACGCGGGCATCGACGCAGGGGCCGTGCAGCCGATGGGCATCGAGAAGTTCCAGCGTGCCCAGGCCA
TTGCGCTGGAGCAGAAGCTGCCGTTCATCCACCTTGTCGAATCGGCCGGCGCCAACCTGCTGACGTATCGCGTGGAGACC
TTCATCCACGGCGGCAGCGGCTTTTACTGGCTCGCGCGGCTGTCGGCGGCGGGCATTCCGGTGATCAGCGTGGTGCATGG
GTCCAGCACGGCGGGCGGCGCCTACATGCCGGGCCTGTCGGACTACGTGGTGATGGTGCGCGACCGGGCGCGCGCGTTCC
TCGCCGGGCCGCCGTTGCTGAAAGCGGCCACGGGCGAGATCGCCACCGAAGAGGAACTGGGCGGTGCGGAGATGCACGCC
ACCACTTCGGGCCTGGCCGAATACCTGGCCGAAGACGATGCGGATGCACTGCGCATCGCGCGCGAACTTGTGGCCGCGCT
CGACTGGAACCGCGATGTGCCGGCACCGGACAGGCCCTATGCGCCGCCGCGCTTCGATGCAGAAGAACTGCTTGGCATTG
CGCTGACCGATCATCGCAAACCGCTGGACATGCGCGAGGTCATTGCACGCTTTGCCGATGGATCGGATTTTCTGGAGTTC
AAGCCTGACTATGGCCCCGGCACGATCACGGGGCATGCGGCCATCTGTGGCATGCGCGTCGGCGTCATCACAAACAACGG
GCCGCTGGACCCGGCGGGCGCGACCAAGGTGGTGCATTTCATTCAGGTGTGCTGCCAGTCCGACACGCCGCTGCTGTATC
TGCAAAACACCACCGGTTTCATCGTCGGCAAGGCGTCGGAACAGGCCGGCATGATCAAGCACGGCTCGAAGACGATCCAG
GCCATGGCCAACGCCACCGTGCCGCGCATCACCGTGCATTGCGGCGCGTCGTTTGGCGCGGGCAACTACGGCATGTCGGG
GCGCGGCTTCTTTCCGGATTTTTGCTTCAGCTGGCCCAACGCCAAGACGGCTGTGATGGGCGCCGAGCAGGCCGCCGGAA
CGATGGCGACGGTCATGGCCGCGAGCATGCAACGCAAGACGCAGACCGTCGACCATGACGCCATTGAAGCGATGCGCGCC
AAGGTGATCGACACGTTCGAGCGGCAGTCCGATGCATTCACCGTTTCGGGCCGATTGCTGGACGACGGCGTGATCGACCC
GCGCGACACACGCAAGGTGCTGGCCTGCGTGCTCGGGGTGTGCGACGAAGCGCGCCGCCGCACGTTGCATCCGATCCAGT
TTGGCGTTGCGCGCCCGTAG

Upstream 100 bases:

>100_bases
CCCGGTTCGCCCATGCCGGCTCCGCGTCATGGTGCCGAGCCGTTCAACGGCTTCCACCTGGCCGTGACGCCCAAGGTGCT
GCAAGGCGAGGAGGACCGCC

Downstream 100 bases:

>100_bases
CCATCCCGACCCATACACGAACAGCCCAGGACAACCGGAGCGAGACACCATGCACTTCACCCACGAGCACCAGGAACTGC
AGCGCAACCTGAAACGCTTC

Product: carboxyl transferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MPALESRIVPQSDAYRQNHAALTELVGRLRTLEDRTRDKSEASRARFEQRGQLLPRDRLGRLLDAGAPFLELSTLAGFCL
DHADPARSIPGGGFIAGIGWVSGVRAMIIVDDAGIDAGAVQPMGIEKFQRAQAIALEQKLPFIHLVESAGANLLTYRVET
FIHGGSGFYWLARLSAAGIPVISVVHGSSTAGGAYMPGLSDYVVMVRDRARAFLAGPPLLKAATGEIATEEELGGAEMHA
TTSGLAEYLAEDDADALRIARELVAALDWNRDVPAPDRPYAPPRFDAEELLGIALTDHRKPLDMREVIARFADGSDFLEF
KPDYGPGTITGHAAICGMRVGVITNNGPLDPAGATKVVHFIQVCCQSDTPLLYLQNTTGFIVGKASEQAGMIKHGSKTIQ
AMANATVPRITVHCGASFGAGNYGMSGRGFFPDFCFSWPNAKTAVMGAEQAAGTMATVMAASMQRKTQTVDHDAIEAMRA
KVIDTFERQSDAFTVSGRLLDDGVIDPRDTRKVLACVLGVCDEARRRTLHPIQFGVARP

Sequences:

>Translated_539_residues
MPALESRIVPQSDAYRQNHAALTELVGRLRTLEDRTRDKSEASRARFEQRGQLLPRDRLGRLLDAGAPFLELSTLAGFCL
DHADPARSIPGGGFIAGIGWVSGVRAMIIVDDAGIDAGAVQPMGIEKFQRAQAIALEQKLPFIHLVESAGANLLTYRVET
FIHGGSGFYWLARLSAAGIPVISVVHGSSTAGGAYMPGLSDYVVMVRDRARAFLAGPPLLKAATGEIATEEELGGAEMHA
TTSGLAEYLAEDDADALRIARELVAALDWNRDVPAPDRPYAPPRFDAEELLGIALTDHRKPLDMREVIARFADGSDFLEF
KPDYGPGTITGHAAICGMRVGVITNNGPLDPAGATKVVHFIQVCCQSDTPLLYLQNTTGFIVGKASEQAGMIKHGSKTIQ
AMANATVPRITVHCGASFGAGNYGMSGRGFFPDFCFSWPNAKTAVMGAEQAAGTMATVMAASMQRKTQTVDHDAIEAMRA
KVIDTFERQSDAFTVSGRLLDDGVIDPRDTRKVLACVLGVCDEARRRTLHPIQFGVARP
>Mature_538_residues
PALESRIVPQSDAYRQNHAALTELVGRLRTLEDRTRDKSEASRARFEQRGQLLPRDRLGRLLDAGAPFLELSTLAGFCLD
HADPARSIPGGGFIAGIGWVSGVRAMIIVDDAGIDAGAVQPMGIEKFQRAQAIALEQKLPFIHLVESAGANLLTYRVETF
IHGGSGFYWLARLSAAGIPVISVVHGSSTAGGAYMPGLSDYVVMVRDRARAFLAGPPLLKAATGEIATEEELGGAEMHAT
TSGLAEYLAEDDADALRIARELVAALDWNRDVPAPDRPYAPPRFDAEELLGIALTDHRKPLDMREVIARFADGSDFLEFK
PDYGPGTITGHAAICGMRVGVITNNGPLDPAGATKVVHFIQVCCQSDTPLLYLQNTTGFIVGKASEQAGMIKHGSKTIQA
MANATVPRITVHCGASFGAGNYGMSGRGFFPDFCFSWPNAKTAVMGAEQAAGTMATVMAASMQRKTQTVDHDAIEAMRAK
VIDTFERQSDAFTVSGRLLDDGVIDPRDTRKVLACVLGVCDEARRRTLHPIQFGVARP

Specific function: Unknown

COG id: COG4799

COG function: function code I; Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI11545863, Length=507, Percent_Identity=44.5759368836292, Blast_Score=405, Evalue=1e-113,
Organism=Homo sapiens, GI119943100, Length=521, Percent_Identity=29.9424184261036, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI295821216, Length=541, Percent_Identity=29.0203327171904, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI310133460, Length=138, Percent_Identity=43.4782608695652, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17552936, Length=544, Percent_Identity=42.8308823529412, Blast_Score=417, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI25147362, Length=489, Percent_Identity=30.2658486707566, Blast_Score=208, Evalue=7e-54,
Organism=Caenorhabditis elegans, GI25147359, Length=489, Percent_Identity=30.2658486707566, Blast_Score=208, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24586065, Length=555, Percent_Identity=41.0810810810811, Blast_Score=419, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: NA

Molecular weight: Translated: 57832; Mature: 57700

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALESRIVPQSDAYRQNHAALTELVGRLRTLEDRTRDKSEASRARFEQRGQLLPRDRLG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHH
RLLDAGAPFLELSTLAGFCLDHADPARSIPGGGFIAGIGWVSGVRAMIIVDDAGIDAGAV
HHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCCCEEEEEEECCCCCCCCC
QPMGIEKFQRAQAIALEQKLPFIHLVESAGANLLTYRVETFIHGGSGFYWLARLSAAGIP
CCCCHHHHHHHHHHHHHHCCCEEEEHHHCCCCEEEEEEEEEEECCCCCEEEEHHHCCCCC
VISVVHGSSTAGGAYMPGLSDYVVMVRDRARAFLAGPPLLKAATGEIATEEELGGAEMHA
EEEEEECCCCCCCCCCCCCCHHEEEEEHHHHHEECCCCCHHHCCCCCCCHHHCCCCHHHH
TTSGLAEYLAEDDADALRIARELVAALDWNRDVPAPDRPYAPPRFDAEELLGIALTDHRK
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHEEHEECCCC
PLDMREVIARFADGSDFLEFKPDYGPGTITGHAAICGMRVGVITNNGPLDPAGATKVVHF
CCCHHHHHHHHCCCCCCEEECCCCCCCCEECCHHEEEEEEEEEECCCCCCCCHHHHHHHH
IQVCCQSDTPLLYLQNTTGFIVGKASEQAGMIKHGSKTIQAMANATVPRITVHCGASFGA
HHHHHCCCCCEEEEECCCEEEEECCCCCCCCHHCCHHHHHHHHCCCCCEEEEEECCCCCC
GNYGMSGRGFFPDFCFSWPNAKTAVMGAEQAAGTMATVMAASMQRKTQTVDHDAIEAMRA
CCCCCCCCCCCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KVIDTFERQSDAFTVSGRLLDDGVIDPRDTRKVLACVLGVCDEARRRTLHPIQFGVARP
HHHHHHHHCCCCEEEECEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCC
>Mature Secondary Structure 
PALESRIVPQSDAYRQNHAALTELVGRLRTLEDRTRDKSEASRARFEQRGQLLPRDRLG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHH
RLLDAGAPFLELSTLAGFCLDHADPARSIPGGGFIAGIGWVSGVRAMIIVDDAGIDAGAV
HHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEHHHHHCCCEEEEEEECCCCCCCCC
QPMGIEKFQRAQAIALEQKLPFIHLVESAGANLLTYRVETFIHGGSGFYWLARLSAAGIP
CCCCHHHHHHHHHHHHHHCCCEEEEHHHCCCCEEEEEEEEEEECCCCCEEEEHHHCCCCC
VISVVHGSSTAGGAYMPGLSDYVVMVRDRARAFLAGPPLLKAATGEIATEEELGGAEMHA
EEEEEECCCCCCCCCCCCCCHHEEEEEHHHHHEECCCCCHHHCCCCCCCHHHCCCCHHHH
TTSGLAEYLAEDDADALRIARELVAALDWNRDVPAPDRPYAPPRFDAEELLGIALTDHRK
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHEEHEECCCC
PLDMREVIARFADGSDFLEFKPDYGPGTITGHAAICGMRVGVITNNGPLDPAGATKVVHF
CCCHHHHHHHHCCCCCCEEECCCCCCCCEECCHHEEEEEEEEEECCCCCCCCHHHHHHHH
IQVCCQSDTPLLYLQNTTGFIVGKASEQAGMIKHGSKTIQAMANATVPRITVHCGASFGA
HHHHHCCCCCEEEEECCCEEEEECCCCCCCCHHCCHHHHHHHHCCCCCEEEEEECCCCCC
GNYGMSGRGFFPDFCFSWPNAKTAVMGAEQAAGTMATVMAASMQRKTQTVDHDAIEAMRA
CCCCCCCCCCCCHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
KVIDTFERQSDAFTVSGRLLDDGVIDPRDTRKVLACVLGVCDEARRRTLHPIQFGVARP
HHHHHHHHCCCCEEEECEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377; 9387222 [H]