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The map label for this gene is mmgC [H]

Identifier: 187927215

GI number: 187927215

Start: 125090

End: 126247

Strand: Direct

Name: mmgC [H]

Synonym: Rpic_0107

Alternate gene names: 187927215

Gene position: 125090-126247 (Clockwise)

Preceding gene: 187927214

Following gene: 187927216

Centisome position: 3.17

GC content: 63.3

Gene sequence:

>1158_bases
ATGCACTTCACCCACGAGCACCAGGAACTGCAGCGCAACCTGAAACGCTTCATCGACAGCGACATCAACCCGTACGTCGA
TGAATGGGAAGCGGCGGAGATGTTTCCCGCCAAGCAGCTCTTCAAGAAGATGGGCGAGTTGGGCTTTCTCGGCATCGCCA
AGCCGACCGAGTTTGGCGGCCTGGGGCTCGACTATTCGTATGCGATGGCGATGGCCGAGACGCTGGGGCACATCCACTGC
GGCGGCGTGCCGATGGCGATTGGCGTGCAGACCGACATGGCGACGCCCGCGCTCGCACGCTTCGGTTCGGACGAGCTGCG
CGCACAGTTTCTCGCCCCCGCCATCAGCGGCGATGCGGTGGCGTGCGTTGGCGTATCGGAGCCGAGCGCTGGCTCCGATG
TGGCAAGCATCAAGACCACGGCGCGCAAGGACGGCGACGACTACATCATCAACGGCAGCAAGATGTGGATCACCAACAGC
CTACAGGCCGACTGGATGTGCTTGCTGGCCAACACGTCGGACGACCCCGCCCACCGCAACAAGTCGCTCATCATCGTGCC
GATGAACACGAAGGGCGTGTCGGTCGGCAAGAAGATCCGCAAGATCGGCATGAATTCGTCGGACACGGGCCTCATCTATT
TTGACGATGTGCGCGTGCCACAGCGCTATCGCATCGGCGAGGAAGGCAAGGGCTTCACGTACCAGATGCTGCAATTCCAG
GAAGAGCGCCTGTGGGCCGCGGCCAGCAGCCTGGCGACGATGACGATGTGCATCGAGACCACCGCCGAGTACGCACGCGA
GCGCAAGCTCTTCGGCGCCAGCCTGCTCGACAACCAGTGGGTGCACTTCAAGCTGGCCGAGCTGAAGACGGAAGTGGAAG
CGCTGCGTGCGCTCACGTATCGCGCGTGCGATCTGTACATCCAAGGGCAGGACGTGACGGAGCTGGCATCGATGGCCAAG
CTCAAGGCCGGGCGCCTCGCGCGCATCGTGCCTGATGCCTGCCTGCAGTTCTGGGGCGGCATGGGCTTCACGTGGGACAA
CCCGGTCTCGCGCTATTACCGCGACGGGCGCCTGGGCTCGATTGGCGGCGGTGCGGACGAGGTGATGCTCGGCATCATCT
GCAAGTACATGAACACGCTGCCGGGCAAGAAGGGCTGA

Upstream 100 bases:

>100_bases
GCGCGCCGCCGCACGTTGCATCCGATCCAGTTTGGCGTTGCGCGCCCGTAGCCATCCCGACCCATACACGAACAGCCCAG
GACAACCGGAGCGAGACACC

Downstream 100 bases:

>100_bases
AAGATGACCGCCCCGCATGCCGCCTTCCGCTCGATCCTCATCGCCAACCGGGGCGAGATCGCTTTGCGCATCATGCGCAC
GGCGCGTCGCCTTGGCATGC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MHFTHEHQELQRNLKRFIDSDINPYVDEWEAAEMFPAKQLFKKMGELGFLGIAKPTEFGGLGLDYSYAMAMAETLGHIHC
GGVPMAIGVQTDMATPALARFGSDELRAQFLAPAISGDAVACVGVSEPSAGSDVASIKTTARKDGDDYIINGSKMWITNS
LQADWMCLLANTSDDPAHRNKSLIIVPMNTKGVSVGKKIRKIGMNSSDTGLIYFDDVRVPQRYRIGEEGKGFTYQMLQFQ
EERLWAAASSLATMTMCIETTAEYARERKLFGASLLDNQWVHFKLAELKTEVEALRALTYRACDLYIQGQDVTELASMAK
LKAGRLARIVPDACLQFWGGMGFTWDNPVSRYYRDGRLGSIGGGADEVMLGIICKYMNTLPGKKG

Sequences:

>Translated_385_residues
MHFTHEHQELQRNLKRFIDSDINPYVDEWEAAEMFPAKQLFKKMGELGFLGIAKPTEFGGLGLDYSYAMAMAETLGHIHC
GGVPMAIGVQTDMATPALARFGSDELRAQFLAPAISGDAVACVGVSEPSAGSDVASIKTTARKDGDDYIINGSKMWITNS
LQADWMCLLANTSDDPAHRNKSLIIVPMNTKGVSVGKKIRKIGMNSSDTGLIYFDDVRVPQRYRIGEEGKGFTYQMLQFQ
EERLWAAASSLATMTMCIETTAEYARERKLFGASLLDNQWVHFKLAELKTEVEALRALTYRACDLYIQGQDVTELASMAK
LKAGRLARIVPDACLQFWGGMGFTWDNPVSRYYRDGRLGSIGGGADEVMLGIICKYMNTLPGKKG
>Mature_385_residues
MHFTHEHQELQRNLKRFIDSDINPYVDEWEAAEMFPAKQLFKKMGELGFLGIAKPTEFGGLGLDYSYAMAMAETLGHIHC
GGVPMAIGVQTDMATPALARFGSDELRAQFLAPAISGDAVACVGVSEPSAGSDVASIKTTARKDGDDYIINGSKMWITNS
LQADWMCLLANTSDDPAHRNKSLIIVPMNTKGVSVGKKIRKIGMNSSDTGLIYFDDVRVPQRYRIGEEGKGFTYQMLQFQ
EERLWAAASSLATMTMCIETTAEYARERKLFGASLLDNQWVHFKLAELKTEVEALRALTYRACDLYIQGQDVTELASMAK
LKAGRLARIVPDACLQFWGGMGFTWDNPVSRYYRDGRLGSIGGGADEVMLGIICKYMNTLPGKKG

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=378, Percent_Identity=34.6560846560847, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI4501857, Length=376, Percent_Identity=32.9787234042553, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI4501859, Length=379, Percent_Identity=31.9261213720317, Blast_Score=209, Evalue=4e-54,
Organism=Homo sapiens, GI4557231, Length=378, Percent_Identity=34.6560846560847, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI187960098, Length=378, Percent_Identity=34.6560846560847, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI226958412, Length=382, Percent_Identity=31.413612565445, Blast_Score=195, Evalue=5e-50,
Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=33.0687830687831, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI226958414, Length=367, Percent_Identity=32.1525885558583, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4557235, Length=370, Percent_Identity=30.5405405405405, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI76496475, Length=370, Percent_Identity=30.5405405405405, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI21361497, Length=341, Percent_Identity=29.9120234604106, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI38505218, Length=398, Percent_Identity=27.6381909547739, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI211971008, Length=286, Percent_Identity=27.6223776223776, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI48976061, Length=286, Percent_Identity=27.6223776223776, Blast_Score=121, Evalue=9e-28,
Organism=Homo sapiens, GI7669494, Length=364, Percent_Identity=27.4725274725275, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI4503943, Length=356, Percent_Identity=27.8089887640449, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI87081958, Length=375, Percent_Identity=30.9333333333333, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1786223, Length=347, Percent_Identity=28.2420749279539, Blast_Score=138, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI17551932, Length=376, Percent_Identity=52.6595744680851, Blast_Score=401, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17505929, Length=376, Percent_Identity=53.1914893617021, Blast_Score=396, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17508101, Length=377, Percent_Identity=32.3607427055703, Blast_Score=223, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17570075, Length=380, Percent_Identity=32.6315789473684, Blast_Score=212, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17506239, Length=367, Percent_Identity=31.0626702997275, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=31.9261213720317, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17534899, Length=380, Percent_Identity=32.1052631578947, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=30.4232804232804, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71990804, Length=292, Percent_Identity=33.9041095890411, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17533517, Length=366, Percent_Identity=31.6939890710383, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=28.8515406162465, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71982178, Length=276, Percent_Identity=30.0724637681159, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=31.4655172413793, Blast_Score=137, Evalue=8e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=287, Percent_Identity=28.2229965156794, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17531909, Length=243, Percent_Identity=28.3950617283951, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17534353, Length=354, Percent_Identity=25.9887005649718, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562446, Length=288, Percent_Identity=27.7777777777778, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21356377, Length=372, Percent_Identity=34.9462365591398, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24646207, Length=383, Percent_Identity=32.8981723237598, Blast_Score=218, Evalue=5e-57,
Organism=Drosophila melanogaster, GI24666513, Length=373, Percent_Identity=32.4396782841823, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=33.7730870712401, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI21355753, Length=380, Percent_Identity=31.5789473684211, Blast_Score=184, Evalue=8e-47,
Organism=Drosophila melanogaster, GI281363737, Length=386, Percent_Identity=29.7927461139896, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19920834, Length=304, Percent_Identity=28.2894736842105, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42508; Mature: 42508

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFTHEHQELQRNLKRFIDSDINPYVDEWEAAEMFPAKQLFKKMGELGFLGIAKPTEFGG
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHCCCCEEECCCCCCCCC
LGLDYSYAMAMAETLGHIHCGGVPMAIGVQTDMATPALARFGSDELRAQFLAPAISGDAV
CCCCHHHHHHHHHHHCCEEECCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCE
ACVGVSEPSAGSDVASIKTTARKDGDDYIINGSKMWITNSLQADWMCLLANTSDDPAHRN
EEEECCCCCCCCCHHHHHHHHCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCC
KSLIIVPMNTKGVSVGKKIRKIGMNSSDTGLIYFDDVRVPQRYRIGEEGKGFTYQMLQFQ
CCEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHCCCCCCCCCHHHHHHHH
EERLWAAASSLATMTMCIETTAEYARERKLFGASLLDNQWVHFKLAELKTEVEALRALTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
RACDLYIQGQDVTELASMAKLKAGRLARIVPDACLQFWGGMGFTWDNPVSRYYRDGRLGS
HHEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCC
IGGGADEVMLGIICKYMNTLPGKKG
CCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MHFTHEHQELQRNLKRFIDSDINPYVDEWEAAEMFPAKQLFKKMGELGFLGIAKPTEFGG
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHCCCCEEECCCCCCCCC
LGLDYSYAMAMAETLGHIHCGGVPMAIGVQTDMATPALARFGSDELRAQFLAPAISGDAV
CCCCHHHHHHHHHHHCCEEECCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHCCCCCCE
ACVGVSEPSAGSDVASIKTTARKDGDDYIINGSKMWITNSLQADWMCLLANTSDDPAHRN
EEEECCCCCCCCCHHHHHHHHCCCCCCEEECCCEEEEECCCCCCEEEEEECCCCCCCCCC
KSLIIVPMNTKGVSVGKKIRKIGMNSSDTGLIYFDDVRVPQRYRIGEEGKGFTYQMLQFQ
CCEEEEECCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHCCCCCCCCCHHHHHHHH
EERLWAAASSLATMTMCIETTAEYARERKLFGASLLDNQWVHFKLAELKTEVEALRALTY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHH
RACDLYIQGQDVTELASMAKLKAGRLARIVPDACLQFWGGMGFTWDNPVSRYYRDGRLGS
HHEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCC
IGGGADEVMLGIICKYMNTLPGKKG
CCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]