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The map label for this gene is rocF [H]

Identifier: 187927161

GI number: 187927161

Start: 63193

End: 64122

Strand: Reverse

Name: rocF [H]

Synonym: Rpic_0051

Alternate gene names: 187927161

Gene position: 64122-63193 (Counterclockwise)

Preceding gene: 187927162

Following gene: 187927158

Centisome position: 1.63

GC content: 69.78

Gene sequence:

>930_bases
ATGACCATCATTGATCTGATCGGCGCGGCCATCGGCTGCGGAGCGCAAGACGACGGCTGCAAGGACGGCCCGCGCGCGCT
GCTGGAAGCCGGCGCGCTGGGGCGATTGCAGACGCGGGACACGCATGCCGCGCTCGTGCACGACATCGAACTGGCGATGT
CAGCTGGGCACAGCCGCTCAGCACGCTTGGCGGCGCTCCCAGGCGTCGCCGGCTTCTCGCGCGCGCTCGGCGACGCGACC
GCGCACAGCGTGCACCAGGGGCATGTGCCCGTGGTCATCGGCGGCGATCACTCCTGTGCCATCGGCACCTGGTCAGGCGT
CGCAAACGCCTTGCGGCCAAGGGGACCGCTTGGCCTGATCTGGATCGACGCCCATCTCGACAGCCACACGCCGCAGACGA
GCGATTCCGGCGCCATCCACGGCATGCCGCTGGCGGCGCTGCTCGGCCACGGAGCAGCGGCCCTCACGCAGATCCGCGAT
GCCGCGCCGAAGCTGCTGCCGGAACACGTGGTGGTGATCGGCGCGCGCAGCTACGAGCCCGCCGAACGCGCGTTGCTTGA
CCTGCTTGGCGTGCGCGTCATCGACGCAGCCGAAGTCGCACGCAATGGTCTGCGCGCCGTCATGGCCGACGCCATCCGCC
AAGTCAAATCGGACACGGCCGCCTTTGGCGTGACACTCGATCTGGACGCCTTTGACCCCGCCGTCGCGCCGGGCGTCGGC
ACGCCCGAAACAGACGGGCTCACCGCGCAGGGCATGGCGCAAGCACTCGCCGCGTGCGCACGCGACGCACGGTTTGCCGC
ATTCGAACTGGTGGAATACAACCCGCGCCACGACAAGGGCGGGATCACGGCACATCTGGCCCTGGACCTCCTGGCCAGCG
TCGCAGGCGCATTGCACGCCCAGCGCCGCGAATACGCGACGGCGGCTTGA

Upstream 100 bases:

>100_bases
CGAGGCCGAACTGGCGCTGGCGCTGGACGCCATCCGCCAGACGCTGGCCGGCTGGCCGCGGCGCAAGGTGGCGTGAGGAA
GAACTCGCAAGGGGAGTGAC

Downstream 100 bases:

>100_bases
ACCGCCATTAAAAAAATCGGACCGCCAACACCCGCGAACAGACGGTGTGGCCGTACCCTGCCCTATGCGACGCCTTGAAT
TTCTGTTGCAAGGAGGAAAA

Product: Arginase/agmatinase/formiminoglutamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTIIDLIGAAIGCGAQDDGCKDGPRALLEAGALGRLQTRDTHAALVHDIELAMSAGHSRSARLAALPGVAGFSRALGDAT
AHSVHQGHVPVVIGGDHSCAIGTWSGVANALRPRGPLGLIWIDAHLDSHTPQTSDSGAIHGMPLAALLGHGAAALTQIRD
AAPKLLPEHVVVIGARSYEPAERALLDLLGVRVIDAAEVARNGLRAVMADAIRQVKSDTAAFGVTLDLDAFDPAVAPGVG
TPETDGLTAQGMAQALAACARDARFAAFELVEYNPRHDKGGITAHLALDLLASVAGALHAQRREYATAA

Sequences:

>Translated_309_residues
MTIIDLIGAAIGCGAQDDGCKDGPRALLEAGALGRLQTRDTHAALVHDIELAMSAGHSRSARLAALPGVAGFSRALGDAT
AHSVHQGHVPVVIGGDHSCAIGTWSGVANALRPRGPLGLIWIDAHLDSHTPQTSDSGAIHGMPLAALLGHGAAALTQIRD
AAPKLLPEHVVVIGARSYEPAERALLDLLGVRVIDAAEVARNGLRAVMADAIRQVKSDTAAFGVTLDLDAFDPAVAPGVG
TPETDGLTAQGMAQALAACARDARFAAFELVEYNPRHDKGGITAHLALDLLASVAGALHAQRREYATAA
>Mature_308_residues
TIIDLIGAAIGCGAQDDGCKDGPRALLEAGALGRLQTRDTHAALVHDIELAMSAGHSRSARLAALPGVAGFSRALGDATA
HSVHQGHVPVVIGGDHSCAIGTWSGVANALRPRGPLGLIWIDAHLDSHTPQTSDSGAIHGMPLAALLGHGAAALTQIRDA
APKLLPEHVVVIGARSYEPAERALLDLLGVRVIDAAEVARNGLRAVMADAIRQVKSDTAAFGVTLDLDAFDPAVAPGVGT
PETDGLTAQGMAQALAACARDARFAAFELVEYNPRHDKGGITAHLALDLLASVAGALHAQRREYATAA

Specific function: Controls arginine catabolism [H]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI4502215, Length=308, Percent_Identity=30.8441558441558, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI10947139, Length=276, Percent_Identity=29.7101449275362, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI37537722, Length=229, Percent_Identity=30.1310043668122, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71996843, Length=303, Percent_Identity=39.2739273927393, Blast_Score=217, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6325146, Length=212, Percent_Identity=31.1320754716981, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24638886, Length=207, Percent_Identity=31.8840579710145, Blast_Score=95, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014033
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.1 [H]

Molecular weight: Translated: 31679; Mature: 31548

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIDLIGAAIGCGAQDDGCKDGPRALLEAGALGRLQTRDTHAALVHDIELAMSAGHSRS
CHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
ARLAALPGVAGFSRALGDATAHSVHQGHVPVVIGGDHSCAIGTWSGVANALRPRGPLGLI
CEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECHHHHHHHHCCCCCEEEE
WIDAHLDSHTPQTSDSGAIHGMPLAALLGHGAAALTQIRDAAPKLLPEHVVVIGARSYEP
EEEEECCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCH
AERALLDLLGVRVIDAAEVARNGLRAVMADAIRQVKSDTAAFGVTLDLDAFDPAVAPGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCC
TPETDGLTAQGMAQALAACARDARFAAFELVEYNPRHDKGGITAHLALDLLASVAGALHA
CCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
QRREYATAA
HHHHHHCCC
>Mature Secondary Structure 
TIIDLIGAAIGCGAQDDGCKDGPRALLEAGALGRLQTRDTHAALVHDIELAMSAGHSRS
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCC
ARLAALPGVAGFSRALGDATAHSVHQGHVPVVIGGDHSCAIGTWSGVANALRPRGPLGLI
CEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECHHHHHHHHCCCCCEEEE
WIDAHLDSHTPQTSDSGAIHGMPLAALLGHGAAALTQIRDAAPKLLPEHVVVIGARSYEP
EEEEECCCCCCCCCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCH
AERALLDLLGVRVIDAAEVARNGLRAVMADAIRQVKSDTAAFGVTLDLDAFDPAVAPGVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCCCCCCCCCC
TPETDGLTAQGMAQALAACARDARFAAFELVEYNPRHDKGGITAHLALDLLASVAGALHA
CCCCCCCCHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHH
QRREYATAA
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8647285; 10196128 [H]