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The map label for this gene is ptsG [H]

Identifier: 187918501

GI number: 187918501

Start: 689475

End: 691019

Strand: Direct

Name: ptsG [H]

Synonym: BH0645

Alternate gene names: 187918501

Gene position: 689475-691019 (Clockwise)

Preceding gene: 187918500

Following gene: 187918505

Centisome position: 74.76

GC content: 35.53

Gene sequence:

>1545_bases
ATGGGGAAATTTTTTGAGAATGCCCAGAAATTTGGGCGTTCTTTTATGTTGCCTATTGCTATTCTTCCTGCGGCAGGATT
ATTTTTAGGTGTTGGAGGTGCTCTCTCTAATCCGGCAACTATCAATGCATATTCTTTTTTGAATGTGTTTTTTATCCAGT
CAGTGTTTAATGTAATGCGTACCGCAGGTGCTATTATTTTTGTTAATTTGCCCCCGATATTTGCAATTGGAGTTGCTGTT
GGACTTGCAAAATCAGACAAAGGAACAGCGGGACTTTCTGCCTTTATTGGGTATCTTGTTTTAAATTCTACTATTGGCAT
TTTAGTTGATATGTTCGGAAAAGCTGAAGATCTCTCAAGTGGAGCTGTTGGGGTGATACTTGGGATTAAAACTTTAGAGA
CAGGCGTTTTTGGTGGGATTATTGTTGGTATTTTGACTTATTATCTTCACAATAAGTTTAATAAAATTGAATTTCCAAGA
GTTCTTGGATTTTTTTCAGGGTCTAGGTTTATACCAATAGTAGTTTCTTGTTCAAATATTCTTCTTGCTGTATGTATGTT
TATATTTTGGCCGTTCATGCAATCTGGAATTAGCAGAGTGGGTGTATTAGTAGATGCGACAGGATATGTTGGTACTCTTA
TTTACGGCATTTTTTTACGAATGCTCGGTCCTTTTGGACTGCATCATATATTTTATTTGCCTTTTTGGACAACTGGTCTT
GGTGGTTCTGAAATTATTAATGGTAAGTTAGTTGAAGGAACTCAGAACATTTTTTTTGCTGAGCTTGCATCTCAGAGTAC
TGATAGATTTTTTATTGGAACTAGTCGTTTTATGAGTGGAAGATTTATTACTATGATGTTTGGACTACCAGGTGCTGCTC
TTGCGCTTTATCGCCTTGCAAAGCCTAGTCAAAAGGCAAAAGTTTTTGGACTTTTGTTTTCATCAGCTTTAACTTCCTTT
TTAACGGGAATTACAGAACCTCTTGAATTTTCTTTTCTTTTTGTAGCACCAGTTCTTTATGTGATTCATGCGGTGTTTGA
TGGTTTTGCATTTATGTTTGCTCATATTCTAGAAATTACAATAGGACAGACTTTTTCTGGAGGATTTATTGATTTTATTC
TTTTTGGGATTTTGCAGGGAAATGCAAGAACAAATTGGATTTTAGTTCCAATGGTAGGTGTTTTCTGGTTCTTCCTATAT
TATTTTAGTTTTACTTTTTTAATATCTAAATTTGACTATAAGACCCCTGGGAGGGAAGATAGTATCAATTCTAATGATGC
ATTTCTTTCTGTTGCAAATGGAAAGAGAGACAATGTTGCGTCTCAAGTAATTATGGGCCTTGGAGGGTCTGATAATATTA
TTGAACTTGATTGTTGCGCCACAAGGCTTAGAGTTACTGTAAAAGATTCTCTGAAAGTTTTAAAAGATACTCTGGAGAAT
ACTGGGGCAAAGGGAATTATTATCAAGAGTAGTGGCGTACAGGTGATTTATGGTCCTGGAGTTAGTGTGCTTAAAAATGA
AATTGAGGAAATTCTTGACAATTAA

Upstream 100 bases:

>100_bases
AATTACGAAAAATTTTGTTGATAAAATAAATGAGGTTAAAGAAATTTGAGTGTTTTTATGATGTCTGATGAGTTTTTTTA
TAGACATATAGGAGGGTTTT

Downstream 100 bases:

>100_bases
TACTGAATTGAATTCTTTAAGAAGTGATATGCTTTTGCATATCACTTGCTTTTTATGTTTTTAATAAAATCAACTGCGTA
CTTTGTTAAATAAGATGTAT

Product: PTS system, glucose-specific IIBC component

Products: NA

Alternate protein names: EII-Glc/EIII-Glc; EIICBA-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MGKFFENAQKFGRSFMLPIAILPAAGLFLGVGGALSNPATINAYSFLNVFFIQSVFNVMRTAGAIIFVNLPPIFAIGVAV
GLAKSDKGTAGLSAFIGYLVLNSTIGILVDMFGKAEDLSSGAVGVILGIKTLETGVFGGIIVGILTYYLHNKFNKIEFPR
VLGFFSGSRFIPIVVSCSNILLAVCMFIFWPFMQSGISRVGVLVDATGYVGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
GGSEIINGKLVEGTQNIFFAELASQSTDRFFIGTSRFMSGRFITMMFGLPGAALALYRLAKPSQKAKVFGLLFSSALTSF
LTGITEPLEFSFLFVAPVLYVIHAVFDGFAFMFAHILEITIGQTFSGGFIDFILFGILQGNARTNWILVPMVGVFWFFLY
YFSFTFLISKFDYKTPGREDSINSNDAFLSVANGKRDNVASQVIMGLGGSDNIIELDCCATRLRVTVKDSLKVLKDTLEN
TGAKGIIIKSSGVQVIYGPGVSVLKNEIEEILDN

Sequences:

>Translated_514_residues
MGKFFENAQKFGRSFMLPIAILPAAGLFLGVGGALSNPATINAYSFLNVFFIQSVFNVMRTAGAIIFVNLPPIFAIGVAV
GLAKSDKGTAGLSAFIGYLVLNSTIGILVDMFGKAEDLSSGAVGVILGIKTLETGVFGGIIVGILTYYLHNKFNKIEFPR
VLGFFSGSRFIPIVVSCSNILLAVCMFIFWPFMQSGISRVGVLVDATGYVGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
GGSEIINGKLVEGTQNIFFAELASQSTDRFFIGTSRFMSGRFITMMFGLPGAALALYRLAKPSQKAKVFGLLFSSALTSF
LTGITEPLEFSFLFVAPVLYVIHAVFDGFAFMFAHILEITIGQTFSGGFIDFILFGILQGNARTNWILVPMVGVFWFFLY
YFSFTFLISKFDYKTPGREDSINSNDAFLSVANGKRDNVASQVIMGLGGSDNIIELDCCATRLRVTVKDSLKVLKDTLEN
TGAKGIIIKSSGVQVIYGPGVSVLKNEIEEILDN
>Mature_513_residues
GKFFENAQKFGRSFMLPIAILPAAGLFLGVGGALSNPATINAYSFLNVFFIQSVFNVMRTAGAIIFVNLPPIFAIGVAVG
LAKSDKGTAGLSAFIGYLVLNSTIGILVDMFGKAEDLSSGAVGVILGIKTLETGVFGGIIVGILTYYLHNKFNKIEFPRV
LGFFSGSRFIPIVVSCSNILLAVCMFIFWPFMQSGISRVGVLVDATGYVGTLIYGIFLRMLGPFGLHHIFYLPFWTTGLG
GSEIINGKLVEGTQNIFFAELASQSTDRFFIGTSRFMSGRFITMMFGLPGAALALYRLAKPSQKAKVFGLLFSSALTSFL
TGITEPLEFSFLFVAPVLYVIHAVFDGFAFMFAHILEITIGQTFSGGFIDFILFGILQGNARTNWILVPMVGVFWFFLYY
FSFTFLISKFDYKTPGREDSINSNDAFLSVANGKRDNVASQVIMGLGGSDNIIELDCCATRLRVTVKDSLKVLKDTLENT
GAKGIIIKSSGVQVIYGPGVSVLKNEIEEILDN

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787908, Length=519, Percent_Identity=38.728323699422, Blast_Score=363, Evalue=1e-101,
Organism=Escherichia coli, GI1787343, Length=515, Percent_Identity=39.8058252427184, Blast_Score=332, Evalue=3e-92,
Organism=Escherichia coli, GI1786894, Length=515, Percent_Identity=34.9514563106796, Blast_Score=234, Evalue=7e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 55834; Mature: 55703

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKFFENAQKFGRSFMLPIAILPAAGLFLGVGGALSNPATINAYSFLNVFFIQSVFNVMR
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
TAGAIIFVNLPPIFAIGVAVGLAKSDKGTAGLSAFIGYLVLNSTIGILVDMFGKAEDLSS
HCCCEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GAVGVILGIKTLETGVFGGIIVGILTYYLHNKFNKIEFPRVLGFFSGSRFIPIVVSCSNI
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEEHHHH
LLAVCMFIFWPFMQSGISRVGVLVDATGYVGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
HHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHCHHHHHHHEEEHHHCCCC
GGSEIINGKLVEGTQNIFFAELASQSTDRFFIGTSRFMSGRFITMMFGLPGAALALYRLA
CCCCCCCCEEECCCHHHHHHHHHCCCCCEEEEECHHHHCCCEEEEEECCCHHHHHHHHHC
KPSQKAKVFGLLFSSALTSFLTGITEPLEFSFLFVAPVLYVIHAVFDGFAFMFAHILEIT
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGQTFSGGFIDFILFGILQGNARTNWILVPMVGVFWFFLYYFSFTFLISKFDYKTPGRED
HCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SINSNDAFLSVANGKRDNVASQVIMGLGGSDNIIELDCCATRLRVTVKDSLKVLKDTLEN
CCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHEEEHHHHHHHHHHHHHC
TGAKGIIIKSSGVQVIYGPGVSVLKNEIEEILDN
CCCCEEEEECCCEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GKFFENAQKFGRSFMLPIAILPAAGLFLGVGGALSNPATINAYSFLNVFFIQSVFNVMR
CCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHH
TAGAIIFVNLPPIFAIGVAVGLAKSDKGTAGLSAFIGYLVLNSTIGILVDMFGKAEDLSS
HCCCEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GAVGVILGIKTLETGVFGGIIVGILTYYLHNKFNKIEFPRVLGFFSGSRFIPIVVSCSNI
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCEEEEEEEHHHH
LLAVCMFIFWPFMQSGISRVGVLVDATGYVGTLIYGIFLRMLGPFGLHHIFYLPFWTTGL
HHHHHHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHHHHHCHHHHHHHEEEHHHCCCC
GGSEIINGKLVEGTQNIFFAELASQSTDRFFIGTSRFMSGRFITMMFGLPGAALALYRLA
CCCCCCCCEEECCCHHHHHHHHHCCCCCEEEEECHHHHCCCEEEEEECCCHHHHHHHHHC
KPSQKAKVFGLLFSSALTSFLTGITEPLEFSFLFVAPVLYVIHAVFDGFAFMFAHILEIT
CCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGQTFSGGFIDFILFGILQGNARTNWILVPMVGVFWFFLYYFSFTFLISKFDYKTPGRED
HCCCCCCHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
SINSNDAFLSVANGKRDNVASQVIMGLGGSDNIIELDCCATRLRVTVKDSLKVLKDTLEN
CCCCCCCEEEECCCCCHHHHHHHHHCCCCCCCEEEEEEHHHHHEEEHHHHHHHHHHHHHC
TGAKGIIIKSSGVQVIYGPGVSVLKNEIEEILDN
CCCCEEEEECCCEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1508157; 9384377; 2497294; 2120236; 1911744; 1906345; 9593197 [H]