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The map label for this gene is murA [H]

Identifier: 187918339

GI number: 187918339

Start: 496375

End: 497688

Strand: Direct

Name: murA [H]

Synonym: BH0472

Alternate gene names: 187918339

Gene position: 496375-497688 (Clockwise)

Preceding gene: 187918338

Following gene: 187918340

Centisome position: 53.82

GC content: 36.68

Gene sequence:

>1314_bases
TTGATGCAAGCTTTGTTTAGTTTGGAGGTAATAATGTATAGCTATCTTTTAGAGGGTGGTTTTAAAATAGGTGGAAAGAT
AACAGCTAGTGGAAATAAGAATGCAGCTTTGCCTTGCATTGTAGCGGCATTGCTTACAGATGAGGAAGTTATTTTAGATA
ATGTTCCAGATATTAAAGATGTAGAAGTTATTTTGCAAATTTTAAAGGACATAGGGGTTGAGGCGTTAAGGGAAGGTAAT
ATCCTTAAAATTAAGGCTTTAAATATTATGAAAACTGAGTTAGATTCTTCCTTGACAGATTTAATTAGAGCCTCAATTTT
GTTGGTGGGACCTATACTTGCTAGGTGTGGGAGAATCGATATTGCTCCCCCTGGTGGAGATGTTATTGGCAAAAGGCGTC
TTGATACTCATTTTTATGGACTTGGTAAGCTTGGTGCTAAGTTAATAGAGAATAAACGGATTGTTTTAGAAATAGATAAA
TTGGTTGGTGCTGAGATGTTTTTAGATGAGGCATCAGTTACTGCCACTGAGAATATTATTATGGCCGCTGTTCTTGCTGT
TGGTGAGACAGTGATAATGAATGCTGCATGTGAACCGCATGTGCAAGATTTATGTAGCATGTTGAATGCTATGGGTGCTG
ATATTTCTGGTATTGGTTCTAATATGCTTAGAATAAAGGGCGTAAAAAAATTAAGTGGAACTAGATTTCGCATAGGTGCT
GATTTCATGCAGGTAGGTTCTTTAATTAGTCTTTCTGCATTAACAGGGGGTGAGCTTGAGATTAACAAGGCTGATCCTAA
GAATTTTATCTTAATAAGACATGTATATTCAAGGCTTGGCATTAATTTTGAGTATGACAACGAAAATATATATGTTAAGG
AAAAACAGTCTTTAAAGGTGAAATTAGATTTTGGGGGACATATTCCCAAGATTGATGACGGACCGTGGCCAGCTTTCCCA
ACAGATCTTATGAGTATAATGATAGTAACTGCAACTCAAGTTCAAGGAACTGTTCTTATTTTTGAGAAAATGTTTGAATC
AAGAATGTTTTTTGTAGACAAGCTTATTAAAATGGGTGCTCAGATCGTTCTTTGTGATCCCCATCGTGTGGTAGTTACAG
GGAAAACTATTCTTAAGGGAAGTAATGTGTCCTCTCCTGATGTTAGGGCTGGTATGTCTTTGCTTATTGCAGCTCTTTGT
GCTAAGGGTGAGAGTCGTATTCAAAATGTTTATCAAATTGAGAGGGGATATGAGGATGTTGTTACCAAGTTAAGTTCTCT
GGGAGCAAAGATTAAGAGAGTGAAAGAGCAATAA

Upstream 100 bases:

>100_bases
GATGGTTGAAGTTGTAAGGGAATACATCGATTTTGATGCTAGTCTTGAGAATAGTAATAACGTTTAAAACGACACCTTTA
ATTTTCTAAAATGTGTTTTA

Downstream 100 bases:

>100_bases
ATTTTATTTTTATTAGGTAAAAGTAAGCTTGCCTTTTTAAGAAAGGCAAGATAATAGAATGTTATTTTTAGTGTTATCCA
GATTTATGGGTTAGTCATGT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 437; Mature: 437

Protein sequence:

>437_residues
MMQALFSLEVIMYSYLLEGGFKIGGKITASGNKNAALPCIVAALLTDEEVILDNVPDIKDVEVILQILKDIGVEALREGN
ILKIKALNIMKTELDSSLTDLIRASILLVGPILARCGRIDIAPPGGDVIGKRRLDTHFYGLGKLGAKLIENKRIVLEIDK
LVGAEMFLDEASVTATENIIMAAVLAVGETVIMNAACEPHVQDLCSMLNAMGADISGIGSNMLRIKGVKKLSGTRFRIGA
DFMQVGSLISLSALTGGELEINKADPKNFILIRHVYSRLGINFEYDNENIYVKEKQSLKVKLDFGGHIPKIDDGPWPAFP
TDLMSIMIVTATQVQGTVLIFEKMFESRMFFVDKLIKMGAQIVLCDPHRVVVTGKTILKGSNVSSPDVRAGMSLLIAALC
AKGESRIQNVYQIERGYEDVVTKLSSLGAKIKRVKEQ

Sequences:

>Translated_437_residues
MMQALFSLEVIMYSYLLEGGFKIGGKITASGNKNAALPCIVAALLTDEEVILDNVPDIKDVEVILQILKDIGVEALREGN
ILKIKALNIMKTELDSSLTDLIRASILLVGPILARCGRIDIAPPGGDVIGKRRLDTHFYGLGKLGAKLIENKRIVLEIDK
LVGAEMFLDEASVTATENIIMAAVLAVGETVIMNAACEPHVQDLCSMLNAMGADISGIGSNMLRIKGVKKLSGTRFRIGA
DFMQVGSLISLSALTGGELEINKADPKNFILIRHVYSRLGINFEYDNENIYVKEKQSLKVKLDFGGHIPKIDDGPWPAFP
TDLMSIMIVTATQVQGTVLIFEKMFESRMFFVDKLIKMGAQIVLCDPHRVVVTGKTILKGSNVSSPDVRAGMSLLIAALC
AKGESRIQNVYQIERGYEDVVTKLSSLGAKIKRVKEQ
>Mature_437_residues
MMQALFSLEVIMYSYLLEGGFKIGGKITASGNKNAALPCIVAALLTDEEVILDNVPDIKDVEVILQILKDIGVEALREGN
ILKIKALNIMKTELDSSLTDLIRASILLVGPILARCGRIDIAPPGGDVIGKRRLDTHFYGLGKLGAKLIENKRIVLEIDK
LVGAEMFLDEASVTATENIIMAAVLAVGETVIMNAACEPHVQDLCSMLNAMGADISGIGSNMLRIKGVKKLSGTRFRIGA
DFMQVGSLISLSALTGGELEINKADPKNFILIRHVYSRLGINFEYDNENIYVKEKQSLKVKLDFGGHIPKIDDGPWPAFP
TDLMSIMIVTATQVQGTVLIFEKMFESRMFFVDKLIKMGAQIVLCDPHRVVVTGKTILKGSNVSSPDVRAGMSLLIAALC
AKGESRIQNVYQIERGYEDVVTKLSSLGAKIKRVKEQ

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=430, Percent_Identity=35.3488372093023, Blast_Score=245, Evalue=5e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 47622; Mature: 47622

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMQALFSLEVIMYSYLLEGGFKIGGKITASGNKNAALPCIVAALLTDEEVILDNVPDIKD
CCHHHHHHHHHHHHHHHHCCEEECCEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCCHH
VEVILQILKDIGVEALREGNILKIKALNIMKTELDSSLTDLIRASILLVGPILARCGRID
HHHHHHHHHHHCHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IAPPGGDVIGKRRLDTHFYGLGKLGAKLIENKRIVLEIDKLVGAEMFLDEASVTATENII
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCHHHHHCCCCHHHHHHHH
MAAVLAVGETVIMNAACEPHVQDLCSMLNAMGADISGIGSNMLRIKGVKKLSGTRFRIGA
HHHHHHHCCHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCCCEEEECH
DFMQVGSLISLSALTGGELEINKADPKNFILIRHVYSRLGINFEYDNENIYVKEKQSLKV
HHHHHCCHHEEEECCCCEEEEECCCCCCEEEHHHHHHHHCCEEEECCCEEEEEECCCEEE
KLDFGGHIPKIDDGPWPAFPTDLMSIMIVTATQVQGTVLIFEKMFESRMFFVDKLIKMGA
EEECCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QIVLCDPHRVVVTGKTILKGSNVSSPDVRAGMSLLIAALCAKGESRIQNVYQIERGYEDV
EEEEECCCEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
VTKLSSLGAKIKRVKEQ
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMQALFSLEVIMYSYLLEGGFKIGGKITASGNKNAALPCIVAALLTDEEVILDNVPDIKD
CCHHHHHHHHHHHHHHHHCCEEECCEEEECCCCCCHHHHHHHHHHCCCHHHHCCCCCCHH
VEVILQILKDIGVEALREGNILKIKALNIMKTELDSSLTDLIRASILLVGPILARCGRID
HHHHHHHHHHHCHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
IAPPGGDVIGKRRLDTHFYGLGKLGAKLIENKRIVLEIDKLVGAEMFLDEASVTATENII
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHCHHHHHCCCCHHHHHHHH
MAAVLAVGETVIMNAACEPHVQDLCSMLNAMGADISGIGSNMLRIKGVKKLSGTRFRIGA
HHHHHHHCCHHEEECCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHCCCCEEEECH
DFMQVGSLISLSALTGGELEINKADPKNFILIRHVYSRLGINFEYDNENIYVKEKQSLKV
HHHHHCCHHEEEECCCCEEEEECCCCCCEEEHHHHHHHHCCEEEECCCEEEEEECCCEEE
KLDFGGHIPKIDDGPWPAFPTDLMSIMIVTATQVQGTVLIFEKMFESRMFFVDKLIKMGA
EEECCCCCCCCCCCCCCCCHHHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHCCC
QIVLCDPHRVVVTGKTILKGSNVSSPDVRAGMSLLIAALCAKGESRIQNVYQIERGYEDV
EEEEECCCEEEEECCEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHH
VTKLSSLGAKIKRVKEQ
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]