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The map label for this gene is xerD [H]

Identifier: 187736389

GI number: 187736389

Start: 2311998

End: 2312885

Strand: Direct

Name: xerD [H]

Synonym: Amuc_1906

Alternate gene names: 187736389

Gene position: 2311998-2312885 (Clockwise)

Preceding gene: 187736388

Following gene: 187736390

Centisome position: 86.78

GC content: 51.91

Gene sequence:

>888_bases
ATGCAAACTCATTTGGAACGCTTCATCCGTTTTCTGGCCGCGGAGAAAGGCCTGAGCACCGCCTACCAGCTTTCCGTGAG
ACAGACCCTGGAGGAATTTGCCCGGTTTCTGGAAATGGATAATACCGGCCTTGCCCAAACGGGCATCGACACGCTTTCGG
CATTTCTGCGGCATTTGCAGGACCGGGGCATGGCCCGCAGCTCCATGCGGGTGGAAATGGTGCATCTGCGTATTTTTTTC
CGGTGGCTGGCCGGAACGGGAATACTGGAAAAAGACCCTTCCGTATTTCTGGAAATGCCCCGGCAGGGGTTGTCGCTTCC
TCATGTGCTGGATCAGAAAACCGTCTCAAATTTGCTTGAAAGCATTGACATTCAAGATATTCCTCTGGGATGTAGAGACA
GAGCGCTTCTGGAGATGATTTACGCCTGCGGGATGCGTGTTAGTGAAATAATTAATTGCAAATTAGAGAGTTTTGATAAA
GATGAAGCTTTTGTCCGCGTGCTGGGGAAGGGGAATAAAACCCGGCTGGTGCCCGTAGGGAGATCCGCTTTGGATGCTTT
GCAAATGTATTTGGAAAAAGGAAGACCCAAACTGGTCAGGACGGGAACGAAAAGCCACATCTTTCTGACAGTACGCGGCC
GTCCGTTGACGAGGGAGCGGATTCGTCAAATTCTCCGGGAACGCGCCAGAGCCGCAGGACTGGAACAGCATGTTTTCCCG
CATATCCTGCGTCATTCCTTCGCCACGCATCTTCTGGAAAACGGAGCGGATCTGCGTATTATTCAGGAGATGCTGGGCCA
TGCCGATATTTCAACCACCCAGATCTATACGCATTTGGAGCAGCAGCGGCTGAACTCGATTCATCACCGCTTTCATCCCA
GAGGATAG

Upstream 100 bases:

>100_bases
GTTCCGGGGCAGCCGGAATTTCAGAAACCGTCCTCAGAACGTGACGGAATTCCTGTTCCTGGTGGAACGGTTTTAACAGA
TGACAGGAAAAGCAGCCTCC

Downstream 100 bases:

>100_bases
TTCATCATTCATTCCCATGCCGCATTTTTTCACGTCCTCCCAATCATATCATAATCATTTAAATATTAACGGTCGGAGAA
TTATTCTACCGGAATTATAT

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQTHLERFIRFLAAEKGLSTAYQLSVRQTLEEFARFLEMDNTGLAQTGIDTLSAFLRHLQDRGMARSSMRVEMVHLRIFF
RWLAGTGILEKDPSVFLEMPRQGLSLPHVLDQKTVSNLLESIDIQDIPLGCRDRALLEMIYACGMRVSEIINCKLESFDK
DEAFVRVLGKGNKTRLVPVGRSALDALQMYLEKGRPKLVRTGTKSHIFLTVRGRPLTRERIRQILRERARAAGLEQHVFP
HILRHSFATHLLENGADLRIIQEMLGHADISTTQIYTHLEQQRLNSIHHRFHPRG

Sequences:

>Translated_295_residues
MQTHLERFIRFLAAEKGLSTAYQLSVRQTLEEFARFLEMDNTGLAQTGIDTLSAFLRHLQDRGMARSSMRVEMVHLRIFF
RWLAGTGILEKDPSVFLEMPRQGLSLPHVLDQKTVSNLLESIDIQDIPLGCRDRALLEMIYACGMRVSEIINCKLESFDK
DEAFVRVLGKGNKTRLVPVGRSALDALQMYLEKGRPKLVRTGTKSHIFLTVRGRPLTRERIRQILRERARAAGLEQHVFP
HILRHSFATHLLENGADLRIIQEMLGHADISTTQIYTHLEQQRLNSIHHRFHPRG
>Mature_295_residues
MQTHLERFIRFLAAEKGLSTAYQLSVRQTLEEFARFLEMDNTGLAQTGIDTLSAFLRHLQDRGMARSSMRVEMVHLRIFF
RWLAGTGILEKDPSVFLEMPRQGLSLPHVLDQKTVSNLLESIDIQDIPLGCRDRALLEMIYACGMRVSEIINCKLESFDK
DEAFVRVLGKGNKTRLVPVGRSALDALQMYLEKGRPKLVRTGTKSHIFLTVRGRPLTRERIRQILRERARAAGLEQHVFP
HILRHSFATHLLENGADLRIIQEMLGHADISTTQIYTHLEQQRLNSIHHRFHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=292, Percent_Identity=38.3561643835616, Blast_Score=194, Evalue=8e-51,
Organism=Escherichia coli, GI1790244, Length=296, Percent_Identity=35.1351351351351, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1790768, Length=189, Percent_Identity=29.1005291005291, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790767, Length=187, Percent_Identity=28.8770053475936, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33909; Mature: 33909

Theoretical pI: Translated: 10.30; Mature: 10.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTHLERFIRFLAAEKGLSTAYQLSVRQTLEEFARFLEMDNTGLAQTGIDTLSAFLRHLQ
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
DRGMARSSMRVEMVHLRIFFRWLAGTGILEKDPSVFLEMPRQGLSLPHVLDQKTVSNLLE
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHH
SIDIQDIPLGCRDRALLEMIYACGMRVSEIINCKLESFDKDEAFVRVLGKGNKTRLVPVG
HCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECC
RSALDALQMYLEKGRPKLVRTGTKSHIFLTVRGRPLTRERIRQILRERARAAGLEQHVFP
HHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHH
HILRHSFATHLLENGADLRIIQEMLGHADISTTQIYTHLEQQRLNSIHHRFHPRG
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQTHLERFIRFLAAEKGLSTAYQLSVRQTLEEFARFLEMDNTGLAQTGIDTLSAFLRHLQ
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
DRGMARSSMRVEMVHLRIFFRWLAGTGILEKDPSVFLEMPRQGLSLPHVLDQKTVSNLLE
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHH
SIDIQDIPLGCRDRALLEMIYACGMRVSEIINCKLESFDKDEAFVRVLGKGNKTRLVPVG
HCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECC
RSALDALQMYLEKGRPKLVRTGTKSHIFLTVRGRPLTRERIRQILRERARAAGLEQHVFP
HHHHHHHHHHHHCCCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHH
HILRHSFATHLLENGADLRIIQEMLGHADISTTQIYTHLEQQRLNSIHHRFHPRG
HHHHHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]