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The map label for this gene is yccK [H]

Identifier: 187736289

GI number: 187736289

Start: 2189364

End: 2190482

Strand: Direct

Name: yccK [H]

Synonym: Amuc_1802

Alternate gene names: 187736289

Gene position: 2189364-2190482 (Clockwise)

Preceding gene: 187736288

Following gene: 187736290

Centisome position: 82.18

GC content: 57.91

Gene sequence:

>1119_bases
ATGAAACGCAAGGATTTTTTGAAGATAACATCCGGTTTGGCCTTATCCCTGGTTTCCCGGGGATGGGCCGGGGTGGGTTC
TTCTTTGCTGTCTGACGGTCCGGGGTCTTCTTCCGGGGTGCCGAAGAAGGGTTTTCTTGGGGAATCCCGGCGCCTTGGAG
GCCTGGAAGTTTCCTCTATCGGGCTGGGATGCCTGCCGATGGTGGGTTATTACGGCGGCAAGTATGATAAACAGGAGATG
ATTGCCCTGATACGCCGGGCTTTTGACAAAGGAGTTACTTTTTTTGATACGGCGGAAGTGTACGGGCCTTATACCAGTGA
GGAATGGGTGGGGGAGGCTCTCGCCCCTGTCCGCAACCAGGTCAGGATAGGAACCAAATTCGGTTTTGGCGTGGAGGAAG
GCCGTCCTTCTTCCCTGAACAGCAGGCCCGACCATATCCGGCGTGCGGTAGAAGGTTCCCTCAGGCGTTTGCGTACCGAC
CACATTGACCTGTTTTACCAGCACCGGGTGGACCCGGATGTTCCGATGGAGGAGGTGGCAGGTACGGTGAAGGAACTGAT
GCAGGAGGGAAAAGTGCTGCATTTCGGCCTGTCCGAAGCCGGCGCCCGTTCCATCAGGAGGGCTTATGCCGAGTGTCCGG
TGAGCGCCGTCCAGAGCGAATACGCTATCTGGTGGAGGGAACCGGAGACGAAGATTTTTCCCACGTTGGAAGAGTTGGGC
ATCGGTTTTGTTCCGTATTGTCCGCTGGGGCGCGCCTTTCTGGCAGGAGCCGTCCGGGAGGACAGCCGTTTTCAAAAGCG
GGACCGCCGCGCCACTTTGCCCCGGTTTACTCCGGAAGCCCTCAGATTCAACATGCCGCTGACTGTTCTTGTCCGGGAAT
GGGCGGAACGCAGGGGCATGACTCCGGCCCAGTTCGCCCTGTCCTGGATGCTTTCCCGGAAACCGTGGATTGCGCCTGTT
CCCGGAACAACCAATCCAGCCCATCTGGATGATTTTCTGGGAGGGGCTTCCGTCCGCCTGTCCGAATCGGAACTCAAGGA
ATTCGACCTTGCCTGTTCCAGAATTCCCCTGATGGGGCACCGGGCGGATCCGTTTACGGAGAGCCAGATTGACAAGTAG

Upstream 100 bases:

>100_bases
AGCCGGTGTCATTCCTTTCGACAGAATCGGACAGTTCTTTCTGGAGCATCTGAAATAAGGAGGCCCCGCATCTGAATTTG
GGAAAGAAAGACGGAACGTA

Downstream 100 bases:

>100_bases
TTTTGCCGGCGCGTTTCCTTCCGCTCCGGAAAAATGCCGCGGGACTGTTTGCGGCGGAAGGATGTTAAGCTATTTTTAAG
AAAGAGACATATGATTCTGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MKRKDFLKITSGLALSLVSRGWAGVGSSLLSDGPGSSSGVPKKGFLGESRRLGGLEVSSIGLGCLPMVGYYGGKYDKQEM
IALIRRAFDKGVTFFDTAEVYGPYTSEEWVGEALAPVRNQVRIGTKFGFGVEEGRPSSLNSRPDHIRRAVEGSLRRLRTD
HIDLFYQHRVDPDVPMEEVAGTVKELMQEGKVLHFGLSEAGARSIRRAYAECPVSAVQSEYAIWWREPETKIFPTLEELG
IGFVPYCPLGRAFLAGAVREDSRFQKRDRRATLPRFTPEALRFNMPLTVLVREWAERRGMTPAQFALSWMLSRKPWIAPV
PGTTNPAHLDDFLGGASVRLSESELKEFDLACSRIPLMGHRADPFTESQIDK

Sequences:

>Translated_372_residues
MKRKDFLKITSGLALSLVSRGWAGVGSSLLSDGPGSSSGVPKKGFLGESRRLGGLEVSSIGLGCLPMVGYYGGKYDKQEM
IALIRRAFDKGVTFFDTAEVYGPYTSEEWVGEALAPVRNQVRIGTKFGFGVEEGRPSSLNSRPDHIRRAVEGSLRRLRTD
HIDLFYQHRVDPDVPMEEVAGTVKELMQEGKVLHFGLSEAGARSIRRAYAECPVSAVQSEYAIWWREPETKIFPTLEELG
IGFVPYCPLGRAFLAGAVREDSRFQKRDRRATLPRFTPEALRFNMPLTVLVREWAERRGMTPAQFALSWMLSRKPWIAPV
PGTTNPAHLDDFLGGASVRLSESELKEFDLACSRIPLMGHRADPFTESQIDK
>Mature_372_residues
MKRKDFLKITSGLALSLVSRGWAGVGSSLLSDGPGSSSGVPKKGFLGESRRLGGLEVSSIGLGCLPMVGYYGGKYDKQEM
IALIRRAFDKGVTFFDTAEVYGPYTSEEWVGEALAPVRNQVRIGTKFGFGVEEGRPSSLNSRPDHIRRAVEGSLRRLRTD
HIDLFYQHRVDPDVPMEEVAGTVKELMQEGKVLHFGLSEAGARSIRRAYAECPVSAVQSEYAIWWREPETKIFPTLEELG
IGFVPYCPLGRAFLAGAVREDSRFQKRDRRATLPRFTPEALRFNMPLTVLVREWAERRGMTPAQFALSWMLSRKPWIAPV
PGTTNPAHLDDFLGGASVRLSESELKEFDLACSRIPLMGHRADPFTESQIDK

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436966, Length=329, Percent_Identity=27.6595744680851, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI27436964, Length=318, Percent_Identity=27.9874213836478, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI27436962, Length=318, Percent_Identity=27.9874213836478, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI27436969, Length=341, Percent_Identity=26.9794721407625, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI4504825, Length=329, Percent_Identity=27.6595744680851, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI27436971, Length=318, Percent_Identity=27.0440251572327, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI223718702, Length=225, Percent_Identity=30.2222222222222, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI41152114, Length=229, Percent_Identity=30.1310043668122, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI41327764, Length=199, Percent_Identity=29.6482412060301, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1789375, Length=315, Percent_Identity=28.8888888888889, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI87081735, Length=319, Percent_Identity=27.8996865203762, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI1787674, Length=307, Percent_Identity=30.2931596091205, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788070, Length=310, Percent_Identity=28.7096774193548, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI48994888, Length=128, Percent_Identity=40.625, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1788081, Length=297, Percent_Identity=25.5892255892256, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1789199, Length=334, Percent_Identity=25.1497005988024, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6325169, Length=343, Percent_Identity=27.4052478134111, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323998, Length=320, Percent_Identity=25.625, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319958, Length=292, Percent_Identity=24.3150684931507, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6319951, Length=242, Percent_Identity=28.9256198347107, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=246, Percent_Identity=26.0162601626016, Blast_Score=81, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6325384, Length=298, Percent_Identity=23.489932885906, Blast_Score=78, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24640980, Length=351, Percent_Identity=25.6410256410256, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=25.7971014492754, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24646159, Length=222, Percent_Identity=28.3783783783784, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24646155, Length=158, Percent_Identity=32.9113924050633, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 41414; Mature: 41414

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKDFLKITSGLALSLVSRGWAGVGSSLLSDGPGSSSGVPKKGFLGESRRLGGLEVSSI
CCCHHHHHHHHHHHHHHHHHCCHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHC
GLGCLPMVGYYGGKYDKQEMIALIRRAFDKGVTFFDTAEVYGPYTSEEWVGEALAPVRNQ
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECHHHCCCCCCHHHHHHHHHHHHHH
VRIGTKFGFGVEEGRPSSLNSRPDHIRRAVEGSLRRLRTDHIDLFYQHRVDPDVPMEEVA
EEECCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
GTVKELMQEGKVLHFGLSEAGARSIRRAYAECPVSAVQSEYAIWWREPETKIFPTLEELG
HHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCCCCCHHHCC
IGFVPYCPLGRAFLAGAVREDSRFQKRDRRATLPRFTPEALRFNMPLTVLVREWAERRGM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCHHHHHHHHHHHCCC
TPAQFALSWMLSRKPWIAPVPGTTNPAHLDDFLGGASVRLSESELKEFDLACSRIPLMGH
CHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCCC
RADPFTESQIDK
CCCCCCHHCCCC
>Mature Secondary Structure
MKRKDFLKITSGLALSLVSRGWAGVGSSLLSDGPGSSSGVPKKGFLGESRRLGGLEVSSI
CCCHHHHHHHHHHHHHHHHHCCHHHCHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEHHC
GLGCLPMVGYYGGKYDKQEMIALIRRAFDKGVTFFDTAEVYGPYTSEEWVGEALAPVRNQ
CCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECHHHCCCCCCHHHHHHHHHHHHHH
VRIGTKFGFGVEEGRPSSLNSRPDHIRRAVEGSLRRLRTDHIDLFYQHRVDPDVPMEEVA
EEECCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
GTVKELMQEGKVLHFGLSEAGARSIRRAYAECPVSAVQSEYAIWWREPETKIFPTLEELG
HHHHHHHHCCCEEEECCHHHHHHHHHHHHHHCCHHHHHCCCEEEEECCCCCCCCCHHHCC
IGFVPYCPLGRAFLAGAVREDSRFQKRDRRATLPRFTPEALRFNMPLTVLVREWAERRGM
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCHHHHHHHHHHHCCC
TPAQFALSWMLSRKPWIAPVPGTTNPAHLDDFLGGASVRLSESELKEFDLACSRIPLMGH
CHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHCCCCEEECHHHHHHHHHHHHHCCCCCC
RADPFTESQIDK
CCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]