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The map label for this gene is cobT [H]

Identifier: 187736168

GI number: 187736168

Start: 2038717

End: 2039757

Strand: Reverse

Name: cobT [H]

Synonym: Amuc_1681

Alternate gene names: 187736168

Gene position: 2039757-2038717 (Counterclockwise)

Preceding gene: 187736169

Following gene: 187736167

Centisome position: 76.56

GC content: 61.1

Gene sequence:

>1041_bases
ATGAACAAACTGCATATCCCCCCGTTGGACGAACAGGCCGCAAAAGCGGCCCTGGAACATCAGAAAATTCTGGCCAAGCC
TCCCCTTGCCCTGGGAAAACTGGAACCCGTGGCCATCCGTATTGCCGGCATGACCGGCAATCCCGCGCCGCGCCTGAAGG
ACAAAGCCATAGTCCTGTTCGCCGCGGACCACCACATCGCCGACCACGGCCTCAGCCTGACATCCACGGACGTTACCTAC
ATCCAGACCCGCAACTTCCTTCAGGGCGGAGGCACGATCAACGCCTTTACACGCAACGCGGGAGCACGCCTTTCCGTAGT
GGACGTAGGCGTCAATTACGACTTCGGCGACCTGCCGGGGCTGGTCAAAAGAAAAGTCATGCACGGCGCCAACGACTTCA
GCAGGGGGCCGGCCATGACGCGGGAACAGGCCCTGAAATGCCTGCAAGTGGGCATTGACATGGCCCGTGAAGAAAAAAAC
AAAGGGCTGGACATTGTGGCCGCCGGAGAAATGGGCATTGGCAACACCACCCCCTCTTCCGCCATCGTCGCCGTGCTCAC
GGGCACCCCTGTGGAAACCGTGACGGGACGCGGTTCCGGCGTCAGAGGAGAAGTCATCCGCAAAAAAATAAAACTCATCG
AACAGGGAATCGCCCTGAACAAGCCAGACCCTTCCGATGCCATTGACGTGCTGGCGAAGGTGGGAGGACCGGAAATAGGA
GCCATGGCCGGACTGATGCTGGGGGCGGCCTCCCTGCGCGTTCCCATCGTCATTGACGGCTTCATTGCCGGGGCGGCCGC
GGCCATCGCCCAGGGCATTCGCCCGGAAGCGGCGCAATACTTCATCGGCTCCCACAACTCCGCGGAACCGGGGCATAAGC
TCATTATGGACCACATCGGCGTCACCATGTACATGGACCTGGGCCTCTGCCTGGGGGAAGGCACGGGAGCGGCCCTGTTC
TTTCCCCTGCTGGACGCCGCCACGCGCGTACTTTCTGAAATGAAAACCCTGCCGGAACTGGACATCACCGTTCCGCGCTG
A

Upstream 100 bases:

>100_bases
GCGACCTGGCCCTGGCCATTCGGCTCATGTGGACGACTGCCGCCACGGGTACGCTGGCGTTCACTCTCCTTCTTCTCTTC
ACCCCCCACTTCTGGACATC

Downstream 100 bases:

>100_bases
CCCTTTCTTCCCTGTATCCATGGCTGTCATCACCACCATCCGCTCCGCCTTCGGCTTCCTGACCCGGCTGCCCGTAGGGC
CGTGGCCGCTGCAAAATGAC

Product: nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MNKLHIPPLDEQAAKAALEHQKILAKPPLALGKLEPVAIRIAGMTGNPAPRLKDKAIVLFAADHHIADHGLSLTSTDVTY
IQTRNFLQGGGTINAFTRNAGARLSVVDVGVNYDFGDLPGLVKRKVMHGANDFSRGPAMTREQALKCLQVGIDMAREEKN
KGLDIVAAGEMGIGNTTPSSAIVAVLTGTPVETVTGRGSGVRGEVIRKKIKLIEQGIALNKPDPSDAIDVLAKVGGPEIG
AMAGLMLGAASLRVPIVIDGFIAGAAAAIAQGIRPEAAQYFIGSHNSAEPGHKLIMDHIGVTMYMDLGLCLGEGTGAALF
FPLLDAATRVLSEMKTLPELDITVPR

Sequences:

>Translated_346_residues
MNKLHIPPLDEQAAKAALEHQKILAKPPLALGKLEPVAIRIAGMTGNPAPRLKDKAIVLFAADHHIADHGLSLTSTDVTY
IQTRNFLQGGGTINAFTRNAGARLSVVDVGVNYDFGDLPGLVKRKVMHGANDFSRGPAMTREQALKCLQVGIDMAREEKN
KGLDIVAAGEMGIGNTTPSSAIVAVLTGTPVETVTGRGSGVRGEVIRKKIKLIEQGIALNKPDPSDAIDVLAKVGGPEIG
AMAGLMLGAASLRVPIVIDGFIAGAAAAIAQGIRPEAAQYFIGSHNSAEPGHKLIMDHIGVTMYMDLGLCLGEGTGAALF
FPLLDAATRVLSEMKTLPELDITVPR
>Mature_346_residues
MNKLHIPPLDEQAAKAALEHQKILAKPPLALGKLEPVAIRIAGMTGNPAPRLKDKAIVLFAADHHIADHGLSLTSTDVTY
IQTRNFLQGGGTINAFTRNAGARLSVVDVGVNYDFGDLPGLVKRKVMHGANDFSRGPAMTREQALKCLQVGIDMAREEKN
KGLDIVAAGEMGIGNTTPSSAIVAVLTGTPVETVTGRGSGVRGEVIRKKIKLIEQGIALNKPDPSDAIDVLAKVGGPEIG
AMAGLMLGAASLRVPIVIDGFIAGAAAAIAQGIRPEAAQYFIGSHNSAEPGHKLIMDHIGVTMYMDLGLCLGEGTGAALF
FPLLDAATRVLSEMKTLPELDITVPR

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=341, Percent_Identity=38.7096774193548, Blast_Score=238, Evalue=4e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36262; Mature: 36262

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLHIPPLDEQAAKAALEHQKILAKPPLALGKLEPVAIRIAGMTGNPAPRLKDKAIVLF
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEE
AADHHIADHGLSLTSTDVTYIQTRNFLQGGGTINAFTRNAGARLSVVDVGVNYDFGDLPG
EECCCHHHCCCEEECCCEEEEEECCHHCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCH
LVKRKVMHGANDFSRGPAMTREQALKCLQVGIDMAREEKNKGLDIVAAGEMGIGNTTPSS
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
AIVAVLTGTPVETVTGRGSGVRGEVIRKKIKLIEQGIALNKPDPSDAIDVLAKVGGPEIG
EEEEEEECCCHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHH
AMAGLMLGAASLRVPIVIDGFIAGAAAAIAQGIRPEAAQYFIGSHNSAEPGHKLIMDHIG
HHHHHHHHHHHEEEEEEEECHHHHHHHHHHHCCCCCHHHHEECCCCCCCCHHHHHHHHCC
VTMYMDLGLCLGEGTGAALFFPLLDAATRVLSEMKTLPELDITVPR
EEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC
>Mature Secondary Structure
MNKLHIPPLDEQAAKAALEHQKILAKPPLALGKLEPVAIRIAGMTGNPAPRLKDKAIVLF
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEE
AADHHIADHGLSLTSTDVTYIQTRNFLQGGGTINAFTRNAGARLSVVDVGVNYDFGDLPG
EECCCHHHCCCEEECCCEEEEEECCHHCCCCEEEEEECCCCCEEEEEEECCCCCCCCCCH
LVKRKVMHGANDFSRGPAMTREQALKCLQVGIDMAREEKNKGLDIVAAGEMGIGNTTPSS
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCC
AIVAVLTGTPVETVTGRGSGVRGEVIRKKIKLIEQGIALNKPDPSDAIDVLAKVGGPEIG
EEEEEEECCCHHEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCHHH
AMAGLMLGAASLRVPIVIDGFIAGAAAAIAQGIRPEAAQYFIGSHNSAEPGHKLIMDHIG
HHHHHHHHHHHEEEEEEEECHHHHHHHHHHHCCCCCHHHHEECCCCCCCCHHHHHHHHCC
VTMYMDLGLCLGEGTGAALFFPLLDAATRVLSEMKTLPELDITVPR
EEEEEECCEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA