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The map label for this gene is prmA [H]

Identifier: 187736108

GI number: 187736108

Start: 1946896

End: 1947756

Strand: Reverse

Name: prmA [H]

Synonym: Amuc_1619

Alternate gene names: 187736108

Gene position: 1947756-1946896 (Counterclockwise)

Preceding gene: 187736110

Following gene: 187736105

Centisome position: 73.11

GC content: 54.94

Gene sequence:

>861_bases
ATGACATGGAGTTGGAACAAACTTTCCGCCGCCAAATGGGAAGATGCCTGGAGCGAACGCATCGCCGGAAATCCGAACGC
CGTTATTACAAAAATCAAGGGGGGGAAAACGGTTCGAATCACCGTTTACTGCGATGATGAAGAAGACGCCCTGGCCTTGA
AAAAATATTTTGGAGGAACTGTCAGGGAAATCAAGACGCAGGACTGGGTAGCGACCCAGAAGCGGGAAAAACGCCCTCCG
CTCAAAATAAGGGACGCACTGGTCATTACGGAGCAGAGTTCTCCGGAGAATCTGGCCGCTCTGCAGAAACAGTTCCCCTC
GCGCTGCATCCTGAGCGTTCCCGCCGAAATGGCTTTCGGAACAGGAGACCACGCTACCACATCCACCTGCCTGCGTTTTA
TCTGCGACGCTGCCAAATCCCGCAGAAAAACATCATGGAGCATGACGGACATAGGCTGCGGAACCGCCGTGCTGGCCATG
GCGGCGCTGAAGCTGGGGGCGGAGCACGCCACGGCTTTCGATTTTGACCCCATGGCCATTGAAGTGGCCCGGCACAACAT
GGTCCGCAACGCCGTTACGGCGGAACAGCTGGACTTATTTGTGGAAGACGTCTTCAAATGGAAACCTTCGGAGTCCCAGC
AGGGTGACCTTGTCGTCGCCAACCTGTTTTCAACCATACTGCAAAAGGCTTTTCCACAAATCATCGCCGCCATGAAGAAG
GATGCCGCTTTGGTCATCTCCGGCATTCTGGCTTCCCAGTGGGAAGAAACGAAAACGGCAGCGGAACGTCACGGTCTGTT
CTTTGAACGGGTCGTCAAACGCGGGAAATGGATTACGGCAAAGGGAGGAATGGCCCGGTAG

Upstream 100 bases:

>100_bases
AATTTTCAACAATAGAGCCACACAATCCCAAAAACTGCGAGAATGCAGTTACAATCAATCCATTCTTGCCTCCCTGACGG
AAAAATCCCATACTTTCTGC

Downstream 100 bases:

>100_bases
CAAATAGATCCGCTCCGCATTTTTGTTCCGCCCTCACGGCCCTTCCTTCATCGGAACAGCAATACCCGGCTTCCAGTTCA
AAAATCTCCGCATCCCGGCA

Product: ribosomal L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 286; Mature: 285

Protein sequence:

>286_residues
MTWSWNKLSAAKWEDAWSERIAGNPNAVITKIKGGKTVRITVYCDDEEDALALKKYFGGTVREIKTQDWVATQKREKRPP
LKIRDALVITEQSSPENLAALQKQFPSRCILSVPAEMAFGTGDHATTSTCLRFICDAAKSRRKTSWSMTDIGCGTAVLAM
AALKLGAEHATAFDFDPMAIEVARHNMVRNAVTAEQLDLFVEDVFKWKPSESQQGDLVVANLFSTILQKAFPQIIAAMKK
DAALVISGILASQWEETKTAAERHGLFFERVVKRGKWITAKGGMAR

Sequences:

>Translated_286_residues
MTWSWNKLSAAKWEDAWSERIAGNPNAVITKIKGGKTVRITVYCDDEEDALALKKYFGGTVREIKTQDWVATQKREKRPP
LKIRDALVITEQSSPENLAALQKQFPSRCILSVPAEMAFGTGDHATTSTCLRFICDAAKSRRKTSWSMTDIGCGTAVLAM
AALKLGAEHATAFDFDPMAIEVARHNMVRNAVTAEQLDLFVEDVFKWKPSESQQGDLVVANLFSTILQKAFPQIIAAMKK
DAALVISGILASQWEETKTAAERHGLFFERVVKRGKWITAKGGMAR
>Mature_285_residues
TWSWNKLSAAKWEDAWSERIAGNPNAVITKIKGGKTVRITVYCDDEEDALALKKYFGGTVREIKTQDWVATQKREKRPPL
KIRDALVITEQSSPENLAALQKQFPSRCILSVPAEMAFGTGDHATTSTCLRFICDAAKSRRKTSWSMTDIGCGTAVLAMA
ALKLGAEHATAFDFDPMAIEVARHNMVRNAVTAEQLDLFVEDVFKWKPSESQQGDLVVANLFSTILQKAFPQIIAAMKKD
AALVISGILASQWEETKTAAERHGLFFERVVKRGKWITAKGGMAR

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=166, Percent_Identity=38.5542168674699, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31710; Mature: 31579

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWSWNKLSAAKWEDAWSERIAGNPNAVITKIKGGKTVRITVYCDDEEDALALKKYFGGT
CCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHCCH
VREIKTQDWVATQKREKRPPLKIRDALVITEQSSPENLAALQKQFPSRCILSVPAEMAFG
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCEEHHCCHHHHCC
TGDHATTSTCLRFICDAAKSRRKTSWSMTDIGCGTAVLAMAALKLGAEHATAFDFDPMAI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
EVARHNMVRNAVTAEQLDLFVEDVFKWKPSESQQGDLVVANLFSTILQKAFPQIIAAMKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
DAALVISGILASQWEETKTAAERHGLFFERVVKRGKWITAKGGMAR
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEECCCCCCC
>Mature Secondary Structure 
TWSWNKLSAAKWEDAWSERIAGNPNAVITKIKGGKTVRITVYCDDEEDALALKKYFGGT
CCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCEEEEEEEECCCCHHHHHHHHHCCH
VREIKTQDWVATQKREKRPPLKIRDALVITEQSSPENLAALQKQFPSRCILSVPAEMAFG
HHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHCCCCEEHHCCHHHHCC
TGDHATTSTCLRFICDAAKSRRKTSWSMTDIGCGTAVLAMAALKLGAEHATAFDFDPMAI
CCCCHHHHHHHHHHHHHHHHHCCCCCCCHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHH
EVARHNMVRNAVTAEQLDLFVEDVFKWKPSESQQGDLVVANLFSTILQKAFPQIIAAMKK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
DAALVISGILASQWEETKTAAERHGLFFERVVKRGKWITAKGGMAR
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA