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The map label for this gene is nqo2 [H]

Identifier: 187736102

GI number: 187736102

Start: 1939137

End: 1939718

Strand: Reverse

Name: nqo2 [H]

Synonym: Amuc_1613

Alternate gene names: 187736102

Gene position: 1939718-1939137 (Counterclockwise)

Preceding gene: 187736103

Following gene: 187736101

Centisome position: 72.81

GC content: 57.22

Gene sequence:

>582_bases
ATGTCCGATTACGCTGAAAACGCCATCGACGCGACTATCGCCCACCAGCCCAGCCCGGGCGAACGGTTTTACCCGGCCTT
TGAAGTAACGCCGGAACTTGACGCCGCCGCCAGCGAATACGTTACGCATTACCCGGAAGGCAAGCAAAAATCCGCCGTGC
TGCCCATCCTGCATGAAATACAGAAAAAATTCGGCTTCATCAGCGGCGACGCCATTGCCTGGGTGGGAGAAAAACTGAAT
ATCTCCGCCGCCCATGTTCTGGGCGTGGTGACTTTCTATCCCGGTCTGCGCCAGATGTGCCCCGGAAAAAACCACATCCG
CGTATGCCGCACTCTTTCCTGCGCCATGGCGGGGGCGGACAGCCTGTTCGACGCCATCTGCACGCGTCTGGGCATTGACA
AAAACGGCATCGACCACCACCACCCCATTGGAGTCAGCCCGGACGGCCTGTGGAGCGTGGAAGGAGTGGAATGCCTAGCC
AACTGCGGCTTTGGCCCCAACATGATGGTCAACGATCTCCTGTACGAAAAAGTCACTCCGGAAGTGCTGGAAGAAGTGAT
TGCCAAATATCAGACAGCCTAA

Upstream 100 bases:

>100_bases
CCGGCCATTCTCGGCTCCTTCGACTTCGTGATGGGCGAATGCGACCGTTAAACACCCGCCACTTTCATCCACTTCAACGC
AAACACCAAACTTTTTCCCC

Downstream 100 bases:

>100_bases
CCCTTTCCATTTCCCACGCACCAGATTTTCGCCATGAGCATCACCTATCTTCCCGGTAAAGAACCCCACCCCAGGGAAAC
GCGCCGCATTCTGAAAAACG

Product: NADH dehydrogenase (ubiquinone) 24 kDa subunit

Products: NA

Alternate protein names: NADH dehydrogenase I chain 2; NDH-1 subunit 2 [H]

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MSDYAENAIDATIAHQPSPGERFYPAFEVTPELDAAASEYVTHYPEGKQKSAVLPILHEIQKKFGFISGDAIAWVGEKLN
ISAAHVLGVVTFYPGLRQMCPGKNHIRVCRTLSCAMAGADSLFDAICTRLGIDKNGIDHHHPIGVSPDGLWSVEGVECLA
NCGFGPNMMVNDLLYEKVTPEVLEEVIAKYQTA

Sequences:

>Translated_193_residues
MSDYAENAIDATIAHQPSPGERFYPAFEVTPELDAAASEYVTHYPEGKQKSAVLPILHEIQKKFGFISGDAIAWVGEKLN
ISAAHVLGVVTFYPGLRQMCPGKNHIRVCRTLSCAMAGADSLFDAICTRLGIDKNGIDHHHPIGVSPDGLWSVEGVECLA
NCGFGPNMMVNDLLYEKVTPEVLEEVIAKYQTA
>Mature_192_residues
SDYAENAIDATIAHQPSPGERFYPAFEVTPELDAAASEYVTHYPEGKQKSAVLPILHEIQKKFGFISGDAIAWVGEKLNI
SAAHVLGVVTFYPGLRQMCPGKNHIRVCRTLSCAMAGADSLFDAICTRLGIDKNGIDHHHPIGVSPDGLWSVEGVECLAN
CGFGPNMMVNDLLYEKVTPEVLEEVIAKYQTA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is menaquinone. Couples the redox reaction to proton translocation (for every

COG id: COG1905

COG function: function code C; NADH:ubiquinone oxidoreductase 24 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 24 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI222080062, Length=178, Percent_Identity=34.2696629213483, Blast_Score=101, Evalue=4e-22,
Organism=Escherichia coli, GI1788621, Length=166, Percent_Identity=28.9156626506024, Blast_Score=78, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17561328, Length=175, Percent_Identity=27.4285714285714, Blast_Score=83, Evalue=7e-17,
Organism=Drosophila melanogaster, GI18859877, Length=181, Percent_Identity=28.7292817679558, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355353, Length=162, Percent_Identity=25.3086419753086, Blast_Score=68, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002023
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF01257 Complex1_24kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 20989; Mature: 20858

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYAENAIDATIAHQPSPGERFYPAFEVTPELDAAASEYVTHYPEGKQKSAVLPILHEI
CCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHH
QKKFGFISGDAIAWVGEKLNISAAHVLGVVTFYPGLRQMCPGKNHIRVCRTLSCAMAGAD
HHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHH
SLFDAICTRLGIDKNGIDHHHPIGVSPDGLWSVEGVECLANCGFGPNMMVNDLLYEKVTP
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCH
EVLEEVIAKYQTA
HHHHHHHHHHCCC
>Mature Secondary Structure 
SDYAENAIDATIAHQPSPGERFYPAFEVTPELDAAASEYVTHYPEGKQKSAVLPILHEI
CCHHHHHHHHHHCCCCCCCCCCCCCEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHH
QKKFGFISGDAIAWVGEKLNISAAHVLGVVTFYPGLRQMCPGKNHIRVCRTLSCAMAGAD
HHHHCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHH
SLFDAICTRLGIDKNGIDHHHPIGVSPDGLWSVEGVECLANCGFGPNMMVNDLLYEKVTP
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCH
EVLEEVIAKYQTA
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9020134 [H]