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The map label for this gene is htrB [C]

Identifier: 187736031

GI number: 187736031

Start: 1851613

End: 1853472

Strand: Direct

Name: htrB [C]

Synonym: Amuc_1541

Alternate gene names: 187736031

Gene position: 1851613-1853472 (Clockwise)

Preceding gene: 187736027

Following gene: 187736034

Centisome position: 69.5

GC content: 59.73

Gene sequence:

>1860_bases
ATGAAAGGGTTTCTGCTCATGGAAGGGCTGTTGAAGCTCGTGGGCATGAAAACGCTGTACCGGCTGGGGCGCGCGGCAGG
GGCCGTGGCGTGGCATCTGCTTCCCCAGCGCCGGAACATTGTGGAAAGGAATCTGCGCATCGTTTTGGATCCGGCCCTGC
GCGGAAAGGAACTGCAGAAATTAAGCCGGGAAAATTTCAAAAGGACCATTGCCAATTTCCTGTGTTCCGCGAAGACGGCC
ACCCTGACGGATGAGCAGTTGAAGCATTGCGTGACGGTCGGAGGGCACGAACAGTTTGCCGCGCCTGTGCTGGAAGGGCG
CGGGCAGGTTTGCGCCATAGCCCACTCCGGCAACTGGGAGGCGCTGGCGAGAATACGCGCATTTTACCCAGAGGTGGAGC
GTTACGGGTCCATGTACCGCCAGTTTGACAATCCGCTGATGGAGGAATACGTGTACCAGCGGCGCACGGAACGTGGAACT
CAGATGTTCTCCAAGGAGGGAGGCATCAAGGCTCCCATGAAAATGCTCAAGGAAGGGGGGGCCCTGGGCGTGCTGAGCGA
CCAGTTCGTATGGGAGGGGGTGTATGTCCCCTTTTTCGGCAAGGTGACCGGCACGACTCCGTTGCCCGCTCTGCTGAGAA
AAAGGGCTGGCGCGGACATGGTGGCCATAGCGGTGCGCACGGATGCTCCTGGCCACTGGATAGCGGATATGGGGAATGTG
GTGGATTTTTCCAGGTCGGACGGCTCTCTGGCAGGGGACACGATTGAAGTGAACAGGGGGCTGGAAACGTTGATCCGGGA
ATCCGTGCTGGATGTGTTCTGGATGCACCACCGCTGGAAATCCGTTGACCGCTTTGCCCCGCAGGATAAAAAAACGGCTG
CGCTTCTGGAAAATATGGAGCTGAAGCCGTACCGCATTCTGGTAGCCGTTCCCAGGGCGCTGGATGAAGCCCTGGCGACT
GTTCCCCTGATTCGTGCTTTGAAAACCGTCCGGTGCGACATGCAGGTGAACATCGTCTGCCCGTCTGCCCAGCTGGGGAT
ATGGAAGACGGTGCCGGAAGTTACCCATGTGTTGCCGCACGACTCCCTGAAGCAGCTTCGGGAAGCTTTGGCAGCAGATG
AATTTTACAATGACGGACCGCTGGATCTGGGTGTCATGCTGGATGGAGATATGGAAACCCTGAAAGCGCTGGAACCGTAT
GGCCCCATGATGTTTTCCGGGCTGGACACGCATCCCGGCGCCCGGAAGTACAAATTCCGGGTAAAGGCCCCCGTCCTGCG
CGCCGCCCCCCCGGCGCACCGGGTGCAGCTTTATCTGCAATTGGGGGGGCTGCATGGGCTGGACGTCGCCACCCCGTCTT
TGTTCCCTGTGAAAAAAGCGGCCCCGGCGGAAGACGCCCTCATTTTAATCGCTCCGTTTTCCCGCCTGGGGAGCGCCAGT
GAATGGAGCAGGGAGCAGTGGAGGGAGCTGGTTTCCCTTTTGCCGGGACGGACGGTGCTGGCGGCTCTGGAAGAAGACCG
GGAGCGTGCCGCCTCCCTGGCGGAACATTTGAATGTGGAGCTGGCGGTGGGTGCGCCGGAGGCTCTCTTTCCCGTCATGG
ACGGCGCTGCGGCGGCAGTAGCCGTGGATGGCGACTTTCCGTCCCTCTGTTCTTTCCGGGGGCTTCCGGTGGTGACTCTG
TTTTCCACCCGGCTTCCGGATGTTTACCGCCCTATGGGCACATTCAACCGTTCCCTTTACAGCCACCAGTGCTGTTCTCC
CTGCTTCCGGAAGGAATGTGACCGGGATGTTCCCTGCAACCGCCACATTGCCGTGCGGGAAGTACTGGAAGCCTTGCGGG
AAATTTCCGGGAAAGAATAA

Upstream 100 bases:

>100_bases
GGGGATTCGTATAACATCTTTTCCGGTTTTCCTTATGACTGATTCTTCCTCTCCTGATTCCTCCCCGGCTTCCCGGAATA
CGTTTGCCCATCATTTGGGA

Downstream 100 bases:

>100_bases
TCTGGGAAGGGACGGAATGCCGCCCCCCGGCGTTGGCGGAAAAACGGCGGGAATGCTGCCGTTGCCGTAAAGAATGATGG
AATAACGAAAGGAATTGCGG

Product: lipid A biosynthesis acyltransferase

Products: KDO2-(lauroyl)-lipid IVA [C]

Alternate protein names: Lipid A Biosynthesis Lauroyl Acyltransferase; Acyltransferase; Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis Lauroyl/Myristoyl Acyltransferase; Lipid A Biosynthesis Lauroyl Acyltransferase Subfamily; Bacterial Lipid A Biosynthesis Acyltransferase; Bacterial Lipid A Biosynthesis Acyltransferase Superfamily

Number of amino acids: Translated: 619; Mature: 619

Protein sequence:

>619_residues
MKGFLLMEGLLKLVGMKTLYRLGRAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQKLSRENFKRTIANFLCSAKTA
TLTDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQFDNPLMEEYVYQRRTERGT
QMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFGKVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNV
VDFSRSDGSLAGDTIEVNRGLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENMELKPYRILVAVPRALDEALAT
VPLIRALKTVRCDMQVNIVCPSAQLGIWKTVPEVTHVLPHDSLKQLREALAADEFYNDGPLDLGVMLDGDMETLKALEPY
GPMMFSGLDTHPGARKYKFRVKAPVLRAAPPAHRVQLYLQLGGLHGLDVATPSLFPVKKAAPAEDALILIAPFSRLGSAS
EWSREQWRELVSLLPGRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDGAAAAVAVDGDFPSLCSFRGLPVVTL
FSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCNRHIAVREVLEALREISGKE

Sequences:

>Translated_619_residues
MKGFLLMEGLLKLVGMKTLYRLGRAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQKLSRENFKRTIANFLCSAKTA
TLTDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQFDNPLMEEYVYQRRTERGT
QMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFGKVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNV
VDFSRSDGSLAGDTIEVNRGLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENMELKPYRILVAVPRALDEALAT
VPLIRALKTVRCDMQVNIVCPSAQLGIWKTVPEVTHVLPHDSLKQLREALAADEFYNDGPLDLGVMLDGDMETLKALEPY
GPMMFSGLDTHPGARKYKFRVKAPVLRAAPPAHRVQLYLQLGGLHGLDVATPSLFPVKKAAPAEDALILIAPFSRLGSAS
EWSREQWRELVSLLPGRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDGAAAAVAVDGDFPSLCSFRGLPVVTL
FSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCNRHIAVREVLEALREISGKE
>Mature_619_residues
MKGFLLMEGLLKLVGMKTLYRLGRAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQKLSRENFKRTIANFLCSAKTA
TLTDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWEALARIRAFYPEVERYGSMYRQFDNPLMEEYVYQRRTERGT
QMFSKEGGIKAPMKMLKEGGALGVLSDQFVWEGVYVPFFGKVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNV
VDFSRSDGSLAGDTIEVNRGLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENMELKPYRILVAVPRALDEALAT
VPLIRALKTVRCDMQVNIVCPSAQLGIWKTVPEVTHVLPHDSLKQLREALAADEFYNDGPLDLGVMLDGDMETLKALEPY
GPMMFSGLDTHPGARKYKFRVKAPVLRAAPPAHRVQLYLQLGGLHGLDVATPSLFPVKKAAPAEDALILIAPFSRLGSAS
EWSREQWRELVSLLPGRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDGAAAAVAVDGDFPSLCSFRGLPVVTL
FSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCNRHIAVREVLEALREISGKE

Specific function: Acylates The Intermediate (Kdo)2-Lipid IVa To Form (Kdo)2-(Lauroyl)-Lipid IVa. Has 10 Fold Selectivity For Lauroyl- Acp Over Myristoyl-Acp. [C]

COG id: COG1560

COG function: function code M; Lauroyl/myristoyl acyltransferase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.- [C]

Molecular weight: Translated: 68760; Mature: 68760

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGFLLMEGLLKLVGMKTLYRLGRAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHH
LSRENFKRTIANFLCSAKTATLTDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCHH
ALARIRAFYPEVERYGSMYRQFDNPLMEEYVYQRRTERGTQMFSKEGGIKAPMKMLKEGG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
ALGVLSDQFVWEGVYVPFFGKVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNV
CEEEECCCHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCC
VDFSRSDGSLAGDTIEVNRGLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENME
EECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
LKPYRILVAVPRALDEALATVPLIRALKTVRCDMQVNIVCPSAQLGIWKTVPEVTHVLPH
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
DSLKQLREALAADEFYNDGPLDLGVMLDGDMETLKALEPYGPMMFSGLDTHPGARKYKFR
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCHHCCCCCCCCCCCEEEEE
VKAPVLRAAPPAHRVQLYLQLGGLHGLDVATPSLFPVKKAAPAEDALILIAPFSRLGSAS
ECCCHHHCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHCCCCC
EWSREQWRELVSLLPGRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDGAAAAV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCEEEE
AVDGDFPSLCSFRGLPVVTLFSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCN
EECCCCHHHHHCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
RHIAVREVLEALREISGKE
CCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKGFLLMEGLLKLVGMKTLYRLGRAAGAVAWHLLPQRRNIVERNLRIVLDPALRGKELQK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHH
LSRENFKRTIANFLCSAKTATLTDEQLKHCVTVGGHEQFAAPVLEGRGQVCAIAHSGNWE
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCHH
ALARIRAFYPEVERYGSMYRQFDNPLMEEYVYQRRTERGTQMFSKEGGIKAPMKMLKEGG
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
ALGVLSDQFVWEGVYVPFFGKVTGTTPLPALLRKRAGADMVAIAVRTDAPGHWIADMGNV
CEEEECCCHHHCCEEEEEECCCCCCCCHHHHHHHHCCCCEEEEEEECCCCCCHHHHCCCC
VDFSRSDGSLAGDTIEVNRGLETLIRESVLDVFWMHHRWKSVDRFAPQDKKTAALLENME
EECCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCC
LKPYRILVAVPRALDEALATVPLIRALKTVRCDMQVNIVCPSAQLGIWKTVPEVTHVLPH
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCC
DSLKQLREALAADEFYNDGPLDLGVMLDGDMETLKALEPYGPMMFSGLDTHPGARKYKFR
HHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHCCCCCHHCCCCCCCCCCCEEEEE
VKAPVLRAAPPAHRVQLYLQLGGLHGLDVATPSLFPVKKAAPAEDALILIAPFSRLGSAS
ECCCHHHCCCCHHHEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHCCCCC
EWSREQWRELVSLLPGRTVLAALEEDRERAASLAEHLNVELAVGAPEALFPVMDGAAAAV
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHCCCEEEE
AVDGDFPSLCSFRGLPVVTLFSTRLPDVYRPMGTFNRSLYSHQCCSPCFRKECDRDVPCN
EECCCCHHHHHCCCCCCEEHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCC
RHIAVREVLEALREISGKE
CCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: KDO2-lipid IVA; lauroyl-ACP [C]

Specific reaction: KDO2-lipid IVA + lauroyl-ACP = KDO2-(lauroyl)-lipid IVA + [acyl carrier protein] [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA