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The map label for this gene is dacC [H]

Identifier: 187735971

GI number: 187735971

Start: 1770007

End: 1770978

Strand: Direct

Name: dacC [H]

Synonym: Amuc_1480

Alternate gene names: 187735971

Gene position: 1770007-1770978 (Clockwise)

Preceding gene: 187735966

Following gene: 187735972

Centisome position: 66.44

GC content: 59.26

Gene sequence:

>972_bases
ATGAAAAAGCTATCTCTATTCCTTTTGACCCTGGCCTGTGTATTCCAGTTTTCCGCCCAGGCACAGCAACGGCCCAGTTA
CATTGCCATTGAGGCCAATTCCGGCAAGCTTCTTTTCAGTTCCAACGCAGAAGAAAAAAGGCCCGTGGCCAGTCTTTCCC
AGGTAGCCACCGCCATGGTGGCTTTGGACTGGGTGGCCCGCACGCGGTTGCCGCTGGACACTTTCATTGCCGTGCCCCAG
GAAGCGTTCGGCCTCCGTGCGGGCAATCCCATGGATCTCCAGCCGGGAGACCGCCTGACGCTCCGGGACGCTTTGTATTC
CACCCTGCTGGGTTCGGACAATGTTTCCGCCCTGACTGTTGCCTCCTTTGTGGGGCGTGACCTGGTGTCCCGCCGGGGCG
GCGGCGCCCCCATTGCCGCTTTTGTGGCGGAAATGAACAATTTGGCCCGTTCCCTGAGGATGGCCAAAACGCGCTTTACC
GCTCCCCACGGGCTGGACGCCGGCAACTCCGTTTCCACTTCCTGCGCGCTGGATATGGCCTTGTTGGGCGTTTACAGCAT
GCAAAATCCGGCTTTTTGCTACATTGTTTCCCAGGCGAGCCGGCGCATTGAAGTGCAGTCCCAGACCAAGGGCAGGACGA
TGTACGATATTTCCAACAACAACAGGCTCATGAGCGCTTCCGGCGTGGACGGCATCAAGGCGGGCACTTCCCGCGCCGCC
GGCCCCTGCCTGCTGCTCAGCGTGACGCGCAACGCTATTTCCCGCCGGAGCCCCCAAACGGGGACGGAGGTGATTTATCC
GCAGCGCATGATTATTGCGGTGCTTGGTTCTGCGAGCCGCTATTCCCTCGCCAGGGAGATGATGAACACCGGCTGGCGCG
TTTGGGAAAACTGGCAGGCTTCCGGCATGGATATGAAGGACCCCAAGGAATTTGTCCAGCTTCCTGTGAAATCTGCTCCA
CAAAGGAGATAG

Upstream 100 bases:

>100_bases
TCAATGCGTTTTTCCGTGTCATGACATATAAGTGTTGTACGGAAAACATTTTAGACTTTTCAAATGAGGAGGGAACGGGC
ACTATCCCGCCGGTCCCGCC

Downstream 100 bases:

>100_bases
GAAGTAGACGGGGAAGGATTTTTCTGCTATAAGGAACGCCGAATATGAACATCGGTGTTTTGAATAGCGGGGGTGACTCC
CCCGGGTTGAATGCAGTTAT

Product: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase; Penicillin-binding protein 6; PBP-6 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKKLSLFLLTLACVFQFSAQAQQRPSYIAIEANSGKLLFSSNAEEKRPVASLSQVATAMVALDWVARTRLPLDTFIAVPQ
EAFGLRAGNPMDLQPGDRLTLRDALYSTLLGSDNVSALTVASFVGRDLVSRRGGGAPIAAFVAEMNNLARSLRMAKTRFT
APHGLDAGNSVSTSCALDMALLGVYSMQNPAFCYIVSQASRRIEVQSQTKGRTMYDISNNNRLMSASGVDGIKAGTSRAA
GPCLLLSVTRNAISRRSPQTGTEVIYPQRMIIAVLGSASRYSLAREMMNTGWRVWENWQASGMDMKDPKEFVQLPVKSAP
QRR

Sequences:

>Translated_323_residues
MKKLSLFLLTLACVFQFSAQAQQRPSYIAIEANSGKLLFSSNAEEKRPVASLSQVATAMVALDWVARTRLPLDTFIAVPQ
EAFGLRAGNPMDLQPGDRLTLRDALYSTLLGSDNVSALTVASFVGRDLVSRRGGGAPIAAFVAEMNNLARSLRMAKTRFT
APHGLDAGNSVSTSCALDMALLGVYSMQNPAFCYIVSQASRRIEVQSQTKGRTMYDISNNNRLMSASGVDGIKAGTSRAA
GPCLLLSVTRNAISRRSPQTGTEVIYPQRMIIAVLGSASRYSLAREMMNTGWRVWENWQASGMDMKDPKEFVQLPVKSAP
QRR
>Mature_323_residues
MKKLSLFLLTLACVFQFSAQAQQRPSYIAIEANSGKLLFSSNAEEKRPVASLSQVATAMVALDWVARTRLPLDTFIAVPQ
EAFGLRAGNPMDLQPGDRLTLRDALYSTLLGSDNVSALTVASFVGRDLVSRRGGGAPIAAFVAEMNNLARSLRMAKTRFT
APHGLDAGNSVSTSCALDMALLGVYSMQNPAFCYIVSQASRRIEVQSQTKGRTMYDISNNNRLMSASGVDGIKAGTSRAA
GPCLLLSVTRNAISRRSPQTGTEVIYPQRMIIAVLGSASRYSLAREMMNTGWRVWENWQASGMDMKDPKEFVQLPVKSAP
QRR

Specific function: Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors [H]

COG id: COG1686

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein. Note=N-terminal lies in the periplasmic space [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S11 family [H]

Homologues:

Organism=Escherichia coli, GI1787062, Length=309, Percent_Identity=28.1553398058252, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082022, Length=306, Percent_Identity=26.1437908496732, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1786851, Length=303, Percent_Identity=26.4026402640264, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082054, Length=266, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015956
- InterPro:   IPR018044
- InterPro:   IPR012907
- InterPro:   IPR001967 [H]

Pfam domain/function: PF07943 PBP5_C; PF00768 Peptidase_S11 [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 35137; Mature: 35137

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLSLFLLTLACVFQFSAQAQQRPSYIAIEANSGKLLFSSNAEEKRPVASLSQVATAMV
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHH
ALDWVARTRLPLDTFIAVPQEAFGLRAGNPMDLQPGDRLTLRDALYSTLLGSDNVSALTV
HHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHH
ASFVGRDLVSRRGGGAPIAAFVAEMNNLARSLRMAKTRFTAPHGLDAGNSVSTSCALDMA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LLGVYSMQNPAFCYIVSQASRRIEVQSQTKGRTMYDISNNNRLMSASGVDGIKAGTSRAA
HHHHHHCCCCEEEEEEECCCCEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCC
GPCLLLSVTRNAISRRSPQTGTEVIYPQRMIIAVLGSASRYSLAREMMNTGWRVWENWQA
CCEEEEHHHHHHHHCCCCCCCCEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCEECCCCC
SGMDMKDPKEFVQLPVKSAPQRR
CCCCCCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKLSLFLLTLACVFQFSAQAQQRPSYIAIEANSGKLLFSSNAEEKRPVASLSQVATAMV
CCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHH
ALDWVARTRLPLDTFIAVPQEAFGLRAGNPMDLQPGDRLTLRDALYSTLLGSDNVSALTV
HHHHHHHHCCCHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHH
ASFVGRDLVSRRGGGAPIAAFVAEMNNLARSLRMAKTRFTAPHGLDAGNSVSTSCALDMA
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHH
LLGVYSMQNPAFCYIVSQASRRIEVQSQTKGRTMYDISNNNRLMSASGVDGIKAGTSRAA
HHHHHHCCCCEEEEEEECCCCEEEEECCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCC
GPCLLLSVTRNAISRRSPQTGTEVIYPQRMIIAVLGSASRYSLAREMMNTGWRVWENWQA
CCEEEEHHHHHHHHCCCCCCCCEEECCHHHHHHHHCCCHHHHHHHHHHHCCCCEECCCCC
SGMDMKDPKEFVQLPVKSAPQRR
CCCCCCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3279397; 8905232; 9278503; 7042389 [H]