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The map label for this gene is hypB [H]

Identifier: 187735891

GI number: 187735891

Start: 1671073

End: 1671813

Strand: Direct

Name: hypB [H]

Synonym: Amuc_1398

Alternate gene names: 187735891

Gene position: 1671073-1671813 (Clockwise)

Preceding gene: 187735888

Following gene: 187735892

Centisome position: 62.73

GC content: 56.55

Gene sequence:

>741_bases
ATGTGTAAAGAATGTGGATGCGGGGGGGAGCTCTCCCATGAAAGTCACGGCCACGGCATGGATGTCCATGTTCCGGTGTT
GGATGCCAATGACCGGCTGGCAGAGCGCAACAGAGGTTTTTTTGCTGCAAAAAACCTTTTGGTTATCAATGTTTTTTCTT
CTCCGGGGTCAGGAAAGACTTCTCTGTTGCAGAAGACGGCGGAGATGCTCCGCGGCCGTGTGCGCATGGGGGTTATCGTA
GGGGATTTGGCGACGGATAATGATGCGGAACGCCTGAGCCGAGCGGATATCCCCGTGGTGCAGATTACAACGGGCACCAT
GTGCCATCTGGACGCCCGCATGATTGCGGAGGCCATGAAGAAAATGCCTCTGGACGATCTCGACGTTTTGATTATTGAGA
ATGTGGGCAATCTGGTTTGCCCGGCTTCCTATGACCTGGGGGAAGGCGTGCGCGTGGTGCTGCTTTCCGTGACGGAGGGT
GAGGACAAGCCGTTGAAATATCCTCCCATGTTCCATTCTGCGGATGTTGCCCTGGTGACCAAGTCCGATCTGGCGGATGC
CGTGGATTTTAACCGTGACGCCGCCCTGGCCGCGCTGAACAAGGTGGCTCACCATGCGCACGTGATTGAGGTTTCTTCCA
AGACCGGCGAAGGAATGGAGGCCTGGTGCGAGGAGATTGTGGAACGTGCGCGCCGCGCCCGGGAAGGCACGATTCAGCAT
CATGGCCATCACCACCATTGA

Upstream 100 bases:

>100_bases
TTAAAAAGAAAACCGGGGCAGTTTTGTTTGATTTCATAGGAGTATGACGTGAAACGAATGAGTTTTTTTTCTCTTTGGGA
ATCTAATATCAGTATTGATT

Downstream 100 bases:

>100_bases
ACAGGCCGCCGCGGCATTGAAATTTGAGATAGCCGGCATGGTTCAGGGGGTCGGCTTCCGTCCCCATGTGTACCGTTTGG
CGGTACGGCACGGATTGAAA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 246; Mature: 246

Protein sequence:

>246_residues
MCKECGCGGELSHESHGHGMDVHVPVLDANDRLAERNRGFFAAKNLLVINVFSSPGSGKTSLLQKTAEMLRGRVRMGVIV
GDLATDNDAERLSRADIPVVQITTGTMCHLDARMIAEAMKKMPLDDLDVLIIENVGNLVCPASYDLGEGVRVVLLSVTEG
EDKPLKYPPMFHSADVALVTKSDLADAVDFNRDAALAALNKVAHHAHVIEVSSKTGEGMEAWCEEIVERARRAREGTIQH
HGHHHH

Sequences:

>Translated_246_residues
MCKECGCGGELSHESHGHGMDVHVPVLDANDRLAERNRGFFAAKNLLVINVFSSPGSGKTSLLQKTAEMLRGRVRMGVIV
GDLATDNDAERLSRADIPVVQITTGTMCHLDARMIAEAMKKMPLDDLDVLIIENVGNLVCPASYDLGEGVRVVLLSVTEG
EDKPLKYPPMFHSADVALVTKSDLADAVDFNRDAALAALNKVAHHAHVIEVSSKTGEGMEAWCEEIVERARRAREGTIQH
HGHHHH
>Mature_246_residues
MCKECGCGGELSHESHGHGMDVHVPVLDANDRLAERNRGFFAAKNLLVINVFSSPGSGKTSLLQKTAEMLRGRVRMGVIV
GDLATDNDAERLSRADIPVVQITTGTMCHLDARMIAEAMKKMPLDDLDVLIIENVGNLVCPASYDLGEGVRVVLLSVTEG
EDKPLKYPPMFHSADVALVTKSDLADAVDFNRDAALAALNKVAHHAHVIEVSSKTGEGMEAWCEEIVERARRAREGTIQH
HGHHHH

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=203, Percent_Identity=52.2167487684729, Blast_Score=214, Evalue=6e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 26766; Mature: 26766

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCKECGCGGELSHESHGHGMDVHVPVLDANDRLAERNRGFFAAKNLLVINVFSSPGSGKT
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCEEEECCEEEEEEECCCCCCHH
SLLQKTAEMLRGRVRMGVIVGDLATDNDAERLSRADIPVVQITTGTMCHLDARMIAEAMK
HHHHHHHHHHHCHHHEEEEEECCCCCCHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHHH
KMPLDDLDVLIIENVGNLVCPASYDLGEGVRVVLLSVTEGEDKPLKYPPMFHSADVALVT
HCCCCCCCEEEEECCCCEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEE
KSDLADAVDFNRDAALAALNKVAHHAHVIEVSSKTGEGMEAWCEEIVERARRAREGTIQH
CCHHHHHHCCCCHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHC
HGHHHH
CCCCCC
>Mature Secondary Structure
MCKECGCGGELSHESHGHGMDVHVPVLDANDRLAERNRGFFAAKNLLVINVFSSPGSGKT
CCCCCCCCCCCCCCCCCCCCEEEEEEECCCCHHHHHCCCEEEECCEEEEEEECCCCCCHH
SLLQKTAEMLRGRVRMGVIVGDLATDNDAERLSRADIPVVQITTGTMCHLDARMIAEAMK
HHHHHHHHHHHCHHHEEEEEECCCCCCHHHHHHHCCCCEEEEECCCEEHHHHHHHHHHHH
KMPLDDLDVLIIENVGNLVCPASYDLGEGVRVVLLSVTEGEDKPLKYPPMFHSADVALVT
HCCCCCCCEEEEECCCCEECCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCCEEEEE
KSDLADAVDFNRDAALAALNKVAHHAHVIEVSSKTGEGMEAWCEEIVERARRAREGTIQH
CCHHHHHHCCCCHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHC
HGHHHH
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]