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The map label for this gene is 187735815

Identifier: 187735815

GI number: 187735815

Start: 1599887

End: 1601596

Strand: Direct

Name: 187735815

Synonym: Amuc_1322

Alternate gene names: NA

Gene position: 1599887-1601596 (Clockwise)

Preceding gene: 187735806

Following gene: 187735816

Centisome position: 60.05

GC content: 59.18

Gene sequence:

>1710_bases
ATGTCATCCTCAAAGGCGCAACAAGACGAGTGGTCCGGAAAAATTGGCGTGATTCTCGCTGTGGCCGGCAGTGCCGTCGG
GCTGGGAAATTTTCTGCGCTTTCCGGGGCTGGCTGCCCAATATGGAGGGGGCGCCTTCATGGTGGCTTACGGCCTCATGC
TGGTTCTGGTGGGCGTGCCCGTGGCGTGGGCGGAGTGGTCCATCGGGCGGCGCGGCGGCCAGATGGGCGCCCATTGCGCC
CCCGGCGTGTTCTGGTACCTGACCAAAGGGTCCAGGCTGTGGAAGTTCCTGGGAGTGCTGGCGGTTCTGGGGCCTTCTTC
CGTGGCCTTTTATTACATGGTGGTGGAAGCGTGGTGCTGCGGCTATTTCTGGAAGATGCTCACCTGCCCGGAGGTTTTTG
CCACGGCGGAGGGGACGGCGCAGACTTTTTTCAGTTTCACGGGCATGTACGGCGACGGGAGCGCCCTGTTGTCGGACAAC
GGGCTGCTCTGGATTGTCAGCGGGGTCATCCTTTTGAACCTGGGGATTATTTACCGGGGCATCAGCAAGGGCATCGAAAT
GTTTTCGCGCTGGTTCATGCCGTTGCTGCTTCTGATTTCCCTGGTGCTGCTGGTGCGCATTTTGTGCATCGGCACGCCGG
ACCCTTCTTATCCGGACCGCAGCATCGAACAGGGGCTGGGGTATATGTGGAATCCCGGCAAGGTGCTGGTGGAGGAGCTG
GACCGGAACAGCGGGGACTGGAAGACGGTTTCCATGGTTTCGGCCTCCCAGGCGGGAGCCATGGATGAAGCCGTGCGGCA
GGTGGAAATGTCCGGAGGAACCCGGAGGCTGACTGAGGTGACCCTGTGGGACGGCCTGAAAAACATTGAGCTTTGGATTG
CGGCTGCCGGACAGGTTTTCCTGAGCCTTTCCGTAGGAACGGGGCTGATTCTGACGTATGCCAGCTATGTAAAAAAGAAG
GAGGATATCGCGCTGAGCGGCTTTTCGGCCGCCGCCTCCAATGAAGTGTGCGAGGTGGGCATTGCCGGCATGATGACGGT
TCCCGCCGCCGTGGCGTTCCTGGGAGTGGCCGGAGCCGCCGGGCAGGGGACCTTCGCGCTGGGCTTCATGGTGCTTCCGC
AGGCTTTTGCCAAAATGGGGTCCAGCGTGGTATTCGGCAGCCTGTTTTTCCTGCTTCTGACGGTGGCGGCGGTGACCAGC
TCCATTTCCATGATGCAGGTGGGCCTGTCCTTTATTGAGGAATTCATGGGGCTGAAACGCAAAATGGCTGTGGTGGTGCA
GGGCTTTTTTACGGCTACGGGCACGTTCATCGTTGCCTGGTACAGCGGCAACCTGCTGGCGATGGATACTTATGATTTCT
TTCTGGGCACGCTGTGCTTCTTTGTGAGCGCCATGGTGATGATGATTCTGTTTTCCTGGAAACTGGGGGTGGACCGGGGG
TTGAAGGATCTGGAGGACGGTTCCGTCATCCGCATTCCCAGAATTTACCGTTTCATCATGAAGTTTGTGACGCCTACGCT
GCTGCTGGCGATTTTCCTGGCCTGGCTGGCGCAGAATATCTGGGTGAAGCAGGCCGCGCCCATTGAAGCTCTGGGGCGTG
GGGAACATGGAGCGGTCATTCCCATGGGGTTTCTGGCGGCTTATGCCCTGTTCCTGATTTTCATCACCATGGCTTCCGGA
AGGCATAAGGTGTACCACGGTCCGCGATAG

Upstream 100 bases:

>100_bases
CCAAAAAACGGACGAAAGTCAAGCGGCAATGATATCCCGTTCGTTCCAAAAGAGCCTGTTTTCTCTTGAAAATGAAGCTT
TTTTTGTCAGTATTCCCTCC

Downstream 100 bases:

>100_bases
GCGGGGAAGGCCTGCTGCGCGGATGCCCGTTCCCCGCAGTTTGCGGCAGGCCGGGAGGCAATCCGGAGGCTTGACCGAAG
CCGGATTTGATATAGGCTGG

Product: sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVPVAWAEWSIGRRGGQMGAHCA
PGVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCCGYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDN
GLLWIVSGVILLNLGIIYRGISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEEL
DRNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVFLSLSVGTGLILTYASYVKKK
EDIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAAGQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTS
SISMMQVGLSFIEEFMGLKRKMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRG
LKDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVIPMGFLAAYALFLIFITMASG
RHKVYHGPR

Sequences:

>Translated_569_residues
MSSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVPVAWAEWSIGRRGGQMGAHCA
PGVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCCGYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDN
GLLWIVSGVILLNLGIIYRGISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEEL
DRNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVFLSLSVGTGLILTYASYVKKK
EDIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAAGQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTS
SISMMQVGLSFIEEFMGLKRKMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRG
LKDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVIPMGFLAAYALFLIFITMASG
RHKVYHGPR
>Mature_568_residues
SSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVPVAWAEWSIGRRGGQMGAHCAP
GVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCCGYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDNG
LLWIVSGVILLNLGIIYRGISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEELD
RNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVFLSLSVGTGLILTYASYVKKKE
DIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAAGQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTSS
ISMMQVGLSFIEEFMGLKRKMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRGL
KDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVIPMGFLAAYALFLIFITMASGR
HKVYHGPR

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI289191351, Length=533, Percent_Identity=23.2645403377111, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI4557046, Length=533, Percent_Identity=23.2645403377111, Blast_Score=106, Evalue=8e-23,
Organism=Homo sapiens, GI289191377, Length=533, Percent_Identity=23.2645403377111, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI4507041, Length=523, Percent_Identity=24.8565965583174, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI171184408, Length=565, Percent_Identity=24.9557522123894, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI171184406, Length=565, Percent_Identity=24.9557522123894, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI171184404, Length=565, Percent_Identity=24.9557522123894, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI4507043, Length=556, Percent_Identity=22.6618705035971, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI188528618, Length=525, Percent_Identity=21.3333333333333, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI58219014, Length=617, Percent_Identity=21.7179902755267, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI7657587, Length=543, Percent_Identity=22.2836095764273, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI134304856, Length=413, Percent_Identity=26.634382566586, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI21361581, Length=529, Percent_Identity=23.8185255198488, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI51468073, Length=556, Percent_Identity=21.2230215827338, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI197276623, Length=122, Percent_Identity=36.8852459016393, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI54607094, Length=122, Percent_Identity=36.8852459016393, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI289191353, Length=234, Percent_Identity=25.2136752136752, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI197276625, Length=120, Percent_Identity=36.6666666666667, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI11181770, Length=335, Percent_Identity=22.9850746268657, Blast_Score=67, Evalue=6e-11,
Organism=Homo sapiens, GI92859670, Length=79, Percent_Identity=45.5696202531646, Blast_Score=67, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17555248, Length=155, Percent_Identity=30.3225806451613, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24654186, Length=556, Percent_Identity=26.2589928057554, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24661428, Length=546, Percent_Identity=24.7252747252747, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24655079, Length=584, Percent_Identity=21.5753424657534, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24639516, Length=143, Percent_Identity=34.965034965035, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI221329674, Length=143, Percent_Identity=34.965034965035, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639514, Length=143, Percent_Identity=34.965034965035, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19921936, Length=242, Percent_Identity=28.9256198347107, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI281363702, Length=247, Percent_Identity=27.5303643724696, Blast_Score=69, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281364136, Length=229, Percent_Identity=25.764192139738, Blast_Score=65, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 61521; Mature: 61390

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVP
CCCCCCCCHHCCCCEEEEEEECCCHHCCHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCC
VAWAEWSIGRRGGQMGAHCAPGVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCC
HHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDNGLLWIVSGVILLNLGIIYRG
HHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
ISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEECCHHHHHHHH
DRNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVF
CCCCCCCEEEEEECCHHCCCHHHHHHHHHHCCCCHHHEEEHHHCCCCCEEEEEEECCEEE
LSLSVGTGLILTYASYVKKKEDIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAA
EEEECCCHHHHHHHHHHHHHHCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTSSISMMQVGLSFIEEFMGLKR
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRG
HHHHHHHHHHHCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCC
LKDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVI
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCC
PMGFLAAYALFLIFITMASGRHKVYHGPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVP
CCCCCCCHHCCCCEEEEEEECCCHHCCHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCC
VAWAEWSIGRRGGQMGAHCAPGVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCC
HHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDNGLLWIVSGVILLNLGIIYRG
HHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH
ISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEECCHHHHHHHH
DRNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVF
CCCCCCCEEEEEECCHHCCCHHHHHHHHHHCCCCHHHEEEHHHCCCCCEEEEEEECCEEE
LSLSVGTGLILTYASYVKKKEDIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAA
EEEECCCHHHHHHHHHHHHHHCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTSSISMMQVGLSFIEEFMGLKR
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRG
HHHHHHHHHHHCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCC
LKDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVI
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCC
PMGFLAAYALFLIFITMASGRHKVYHGPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]