Definition | Akkermansia muciniphila ATCC BAA-835, complete genome. |
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Accession | NC_010655 |
Length | 2,664,102 |
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The map label for this gene is 187735815
Identifier: 187735815
GI number: 187735815
Start: 1599887
End: 1601596
Strand: Direct
Name: 187735815
Synonym: Amuc_1322
Alternate gene names: NA
Gene position: 1599887-1601596 (Clockwise)
Preceding gene: 187735806
Following gene: 187735816
Centisome position: 60.05
GC content: 59.18
Gene sequence:
>1710_bases ATGTCATCCTCAAAGGCGCAACAAGACGAGTGGTCCGGAAAAATTGGCGTGATTCTCGCTGTGGCCGGCAGTGCCGTCGG GCTGGGAAATTTTCTGCGCTTTCCGGGGCTGGCTGCCCAATATGGAGGGGGCGCCTTCATGGTGGCTTACGGCCTCATGC TGGTTCTGGTGGGCGTGCCCGTGGCGTGGGCGGAGTGGTCCATCGGGCGGCGCGGCGGCCAGATGGGCGCCCATTGCGCC CCCGGCGTGTTCTGGTACCTGACCAAAGGGTCCAGGCTGTGGAAGTTCCTGGGAGTGCTGGCGGTTCTGGGGCCTTCTTC CGTGGCCTTTTATTACATGGTGGTGGAAGCGTGGTGCTGCGGCTATTTCTGGAAGATGCTCACCTGCCCGGAGGTTTTTG CCACGGCGGAGGGGACGGCGCAGACTTTTTTCAGTTTCACGGGCATGTACGGCGACGGGAGCGCCCTGTTGTCGGACAAC GGGCTGCTCTGGATTGTCAGCGGGGTCATCCTTTTGAACCTGGGGATTATTTACCGGGGCATCAGCAAGGGCATCGAAAT GTTTTCGCGCTGGTTCATGCCGTTGCTGCTTCTGATTTCCCTGGTGCTGCTGGTGCGCATTTTGTGCATCGGCACGCCGG ACCCTTCTTATCCGGACCGCAGCATCGAACAGGGGCTGGGGTATATGTGGAATCCCGGCAAGGTGCTGGTGGAGGAGCTG GACCGGAACAGCGGGGACTGGAAGACGGTTTCCATGGTTTCGGCCTCCCAGGCGGGAGCCATGGATGAAGCCGTGCGGCA GGTGGAAATGTCCGGAGGAACCCGGAGGCTGACTGAGGTGACCCTGTGGGACGGCCTGAAAAACATTGAGCTTTGGATTG CGGCTGCCGGACAGGTTTTCCTGAGCCTTTCCGTAGGAACGGGGCTGATTCTGACGTATGCCAGCTATGTAAAAAAGAAG GAGGATATCGCGCTGAGCGGCTTTTCGGCCGCCGCCTCCAATGAAGTGTGCGAGGTGGGCATTGCCGGCATGATGACGGT TCCCGCCGCCGTGGCGTTCCTGGGAGTGGCCGGAGCCGCCGGGCAGGGGACCTTCGCGCTGGGCTTCATGGTGCTTCCGC AGGCTTTTGCCAAAATGGGGTCCAGCGTGGTATTCGGCAGCCTGTTTTTCCTGCTTCTGACGGTGGCGGCGGTGACCAGC TCCATTTCCATGATGCAGGTGGGCCTGTCCTTTATTGAGGAATTCATGGGGCTGAAACGCAAAATGGCTGTGGTGGTGCA GGGCTTTTTTACGGCTACGGGCACGTTCATCGTTGCCTGGTACAGCGGCAACCTGCTGGCGATGGATACTTATGATTTCT TTCTGGGCACGCTGTGCTTCTTTGTGAGCGCCATGGTGATGATGATTCTGTTTTCCTGGAAACTGGGGGTGGACCGGGGG TTGAAGGATCTGGAGGACGGTTCCGTCATCCGCATTCCCAGAATTTACCGTTTCATCATGAAGTTTGTGACGCCTACGCT GCTGCTGGCGATTTTCCTGGCCTGGCTGGCGCAGAATATCTGGGTGAAGCAGGCCGCGCCCATTGAAGCTCTGGGGCGTG GGGAACATGGAGCGGTCATTCCCATGGGGTTTCTGGCGGCTTATGCCCTGTTCCTGATTTTCATCACCATGGCTTCCGGA AGGCATAAGGTGTACCACGGTCCGCGATAG
Upstream 100 bases:
>100_bases CCAAAAAACGGACGAAAGTCAAGCGGCAATGATATCCCGTTCGTTCCAAAAGAGCCTGTTTTCTCTTGAAAATGAAGCTT TTTTTGTCAGTATTCCCTCC
Downstream 100 bases:
>100_bases GCGGGGAAGGCCTGCTGCGCGGATGCCCGTTCCCCGCAGTTTGCGGCAGGCCGGGAGGCAATCCGGAGGCTTGACCGAAG CCGGATTTGATATAGGCTGG
Product: sodium:neurotransmitter symporter
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 569; Mature: 568
Protein sequence:
>569_residues MSSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVPVAWAEWSIGRRGGQMGAHCA PGVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCCGYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDN GLLWIVSGVILLNLGIIYRGISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEEL DRNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVFLSLSVGTGLILTYASYVKKK EDIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAAGQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTS SISMMQVGLSFIEEFMGLKRKMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRG LKDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVIPMGFLAAYALFLIFITMASG RHKVYHGPR
Sequences:
>Translated_569_residues MSSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVPVAWAEWSIGRRGGQMGAHCA PGVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCCGYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDN GLLWIVSGVILLNLGIIYRGISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEEL DRNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVFLSLSVGTGLILTYASYVKKK EDIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAAGQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTS SISMMQVGLSFIEEFMGLKRKMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRG LKDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVIPMGFLAAYALFLIFITMASG RHKVYHGPR >Mature_568_residues SSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVPVAWAEWSIGRRGGQMGAHCAP GVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCCGYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDNG LLWIVSGVILLNLGIIYRGISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEELD RNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVFLSLSVGTGLILTYASYVKKKE DIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAAGQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTSS ISMMQVGLSFIEEFMGLKRKMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRGL KDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVIPMGFLAAYALFLIFITMASGR HKVYHGPR
Specific function: Putative sodium-dependent transporter [H]
COG id: COG0733
COG function: function code R; Na+-dependent transporters of the SNF family
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]
Homologues:
Organism=Homo sapiens, GI289191351, Length=533, Percent_Identity=23.2645403377111, Blast_Score=106, Evalue=8e-23, Organism=Homo sapiens, GI4557046, Length=533, Percent_Identity=23.2645403377111, Blast_Score=106, Evalue=8e-23, Organism=Homo sapiens, GI289191377, Length=533, Percent_Identity=23.2645403377111, Blast_Score=105, Evalue=1e-22, Organism=Homo sapiens, GI4507041, Length=523, Percent_Identity=24.8565965583174, Blast_Score=103, Evalue=4e-22, Organism=Homo sapiens, GI171184408, Length=565, Percent_Identity=24.9557522123894, Blast_Score=87, Evalue=4e-17, Organism=Homo sapiens, GI171184406, Length=565, Percent_Identity=24.9557522123894, Blast_Score=87, Evalue=4e-17, Organism=Homo sapiens, GI171184404, Length=565, Percent_Identity=24.9557522123894, Blast_Score=87, Evalue=4e-17, Organism=Homo sapiens, GI4507043, Length=556, Percent_Identity=22.6618705035971, Blast_Score=87, Evalue=4e-17, Organism=Homo sapiens, GI188528618, Length=525, Percent_Identity=21.3333333333333, Blast_Score=84, Evalue=4e-16, Organism=Homo sapiens, GI58219014, Length=617, Percent_Identity=21.7179902755267, Blast_Score=81, Evalue=3e-15, Organism=Homo sapiens, GI7657587, Length=543, Percent_Identity=22.2836095764273, Blast_Score=80, Evalue=5e-15, Organism=Homo sapiens, GI134304856, Length=413, Percent_Identity=26.634382566586, Blast_Score=79, Evalue=8e-15, Organism=Homo sapiens, GI21361581, Length=529, Percent_Identity=23.8185255198488, Blast_Score=76, Evalue=1e-13, Organism=Homo sapiens, GI51468073, Length=556, Percent_Identity=21.2230215827338, Blast_Score=75, Evalue=2e-13, Organism=Homo sapiens, GI197276623, Length=122, Percent_Identity=36.8852459016393, Blast_Score=70, Evalue=7e-12, Organism=Homo sapiens, GI54607094, Length=122, Percent_Identity=36.8852459016393, Blast_Score=70, Evalue=7e-12, Organism=Homo sapiens, GI289191353, Length=234, Percent_Identity=25.2136752136752, Blast_Score=69, Evalue=2e-11, Organism=Homo sapiens, GI197276625, Length=120, Percent_Identity=36.6666666666667, Blast_Score=69, Evalue=2e-11, Organism=Homo sapiens, GI11181770, Length=335, Percent_Identity=22.9850746268657, Blast_Score=67, Evalue=6e-11, Organism=Homo sapiens, GI92859670, Length=79, Percent_Identity=45.5696202531646, Blast_Score=67, Evalue=7e-11, Organism=Caenorhabditis elegans, GI17555248, Length=155, Percent_Identity=30.3225806451613, Blast_Score=69, Evalue=5e-12, Organism=Drosophila melanogaster, GI24654186, Length=556, Percent_Identity=26.2589928057554, Blast_Score=115, Evalue=9e-26, Organism=Drosophila melanogaster, GI24661428, Length=546, Percent_Identity=24.7252747252747, Blast_Score=89, Evalue=1e-17, Organism=Drosophila melanogaster, GI24655079, Length=584, Percent_Identity=21.5753424657534, Blast_Score=82, Evalue=7e-16, Organism=Drosophila melanogaster, GI24639516, Length=143, Percent_Identity=34.965034965035, Blast_Score=71, Evalue=2e-12, Organism=Drosophila melanogaster, GI221329674, Length=143, Percent_Identity=34.965034965035, Blast_Score=71, Evalue=2e-12, Organism=Drosophila melanogaster, GI24639514, Length=143, Percent_Identity=34.965034965035, Blast_Score=71, Evalue=3e-12, Organism=Drosophila melanogaster, GI19921936, Length=242, Percent_Identity=28.9256198347107, Blast_Score=70, Evalue=5e-12, Organism=Drosophila melanogaster, GI281363702, Length=247, Percent_Identity=27.5303643724696, Blast_Score=69, Evalue=1e-11, Organism=Drosophila melanogaster, GI281364136, Length=229, Percent_Identity=25.764192139738, Blast_Score=65, Evalue=1e-10,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000175 [H]
Pfam domain/function: PF00209 SNF [H]
EC number: NA
Molecular weight: Translated: 61521; Mature: 61390
Theoretical pI: Translated: 8.43; Mature: 8.43
Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 4.9 %Met (Translated Protein) 6.2 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 4.8 %Met (Mature Protein) 6.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVP CCCCCCCCHHCCCCEEEEEEECCCHHCCHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCC VAWAEWSIGRRGGQMGAHCAPGVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCC HHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH GYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDNGLLWIVSGVILLNLGIIYRG HHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH ISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEEL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEECCHHHHHHHH DRNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVF CCCCCCCEEEEEECCHHCCCHHHHHHHHHHCCCCHHHEEEHHHCCCCCEEEEEEECCEEE LSLSVGTGLILTYASYVKKKEDIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAA EEEECCCHHHHHHHHHHHHHHCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC GQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTSSISMMQVGLSFIEEFMGLKR CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRG HHHHHHHHHHHCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCC LKDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVI CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCC PMGFLAAYALFLIFITMASGRHKVYHGPR HHHHHHHHHHHHHHHHHCCCCCCCCCCCC >Mature Secondary Structure SSSKAQQDEWSGKIGVILAVAGSAVGLGNFLRFPGLAAQYGGGAFMVAYGLMLVLVGVP CCCCCCCHHCCCCEEEEEEECCCHHCCHHHHHCCCCHHHCCCCHHHHHHHHHHHHHCCC VAWAEWSIGRRGGQMGAHCAPGVFWYLTKGSRLWKFLGVLAVLGPSSVAFYYMVVEAWCC HHHHCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH GYFWKMLTCPEVFATAEGTAQTFFSFTGMYGDGSALLSDNGLLWIVSGVILLNLGIIYRG HHHHHHHCCHHHHHCCCCHHHHHHHHHCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHH ISKGIEMFSRWFMPLLLLISLVLLVRILCIGTPDPSYPDRSIEQGLGYMWNPGKVLVEEL HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEECCHHHHHHHH DRNSGDWKTVSMVSASQAGAMDEAVRQVEMSGGTRRLTEVTLWDGLKNIELWIAAAGQVF CCCCCCCEEEEEECCHHCCCHHHHHHHHHHCCCCHHHEEEHHHCCCCCEEEEEEECCEEE LSLSVGTGLILTYASYVKKKEDIALSGFSAAASNEVCEVGIAGMMTVPAAVAFLGVAGAA EEEECCCHHHHHHHHHHHHHHCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC GQGTFALGFMVLPQAFAKMGSSVVFGSLFFLLLTVAAVTSSISMMQVGLSFIEEFMGLKR CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH KMAVVVQGFFTATGTFIVAWYSGNLLAMDTYDFFLGTLCFFVSAMVMMILFSWKLGVDRG HHHHHHHHHHHCCCEEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHCC LKDLEDGSVIRIPRIYRFIMKFVTPTLLLAIFLAWLAQNIWVKQAAPIEALGRGEHGAVI CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCC PMGFLAAYALFLIFITMASGRHKVYHGPR HHHHHHHHHHHHHHHHHCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7542800 [H]