Click here to switch to the map view.

The map label for this gene is pyrH [H]

Identifier: 187735812

GI number: 187735812

Start: 1597158

End: 1597883

Strand: Reverse

Name: pyrH [H]

Synonym: Amuc_1319

Alternate gene names: 187735812

Gene position: 1597883-1597158 (Counterclockwise)

Preceding gene: 187735813

Following gene: 187735811

Centisome position: 59.98

GC content: 60.33

Gene sequence:

>726_bases
ATGTCTGACACATCCGCACCAGCCTATCGAAGAATCCTTCTGAAACTCAGTGGGGAAGCCTTGCGCAGCCCCGGCAGCAT
GGACAACATTTCCCCGGAAATCGTCGCCCGCATTGCTGAAGAAATCGCCCAGGCGCACCGCGCCGGCGTCCAAATAGGCC
TGGTCGTGGGCGGCGGCAATTTCTGGCGCGGGGCGAAAGCCAGCGTGCGCGGCATGGACCGCGCCACGGCGGATTACGTG
GGCATGCTCGCCACCGTGATGAACGCCCTGGCCCTTCAAAGCGCGCTGGAACGCGCGGGGGTCCCCTGCGTGGTGCAATC
CGCCATTGAAATGAAAAATGTCGCGGAATCCTTCATCCGCCTGAAGGCCCGCTCGTATCTGGACAACAATAAAATCGTCA
TCTTCGCCGCCGGCACCGGCAACCCGTTCTTTTCCACGGACACCACGGCTGCCCTGCGCGCCAGCGAAATCAATGCGGAA
GTGGTCATGAAGGCCACCTCCGTGGACGGGGTGTATGATGCGGACCCCAAAAAAGTCTCCGGCGCCAAGCGATTCGACAC
CATCTCCTATCAGGAATGCCTGGAACGCCAGCTCAAAGTAATGGACTCCACGGCCTTCACCCTGTGCATGGACAACAAAA
AGCCCATCATCGTATTCGACATGCATACGCCGGGCAACATCACGCGCGCGCTTCTCGGGGAACCGATCGGCACCACCATC
AGCTGA

Upstream 100 bases:

>100_bases
GGAAATCTCCGGACCTCCGGAGAAAAATCAATAAGGAATCTCTTTTTGCTTTCTTTTTGCCCCGTGAAATTTCAATCTTG
TCTGCGTAAAATCCGCATCT

Downstream 100 bases:

>100_bases
ACCCCGCATTCCTTTTCAACCCACCAAAAACACTTAGCACCCACCATCATCATGGACGCAGAAACATTATTATTGGAAAC
GGAGGAATCCATGCTCAAGG

Product: uridylate kinase

Products: NA

Alternate protein names: UK; Uridine monophosphate kinase; UMP kinase; UMPK [H]

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSDTSAPAYRRILLKLSGEALRSPGSMDNISPEIVARIAEEIAQAHRAGVQIGLVVGGGNFWRGAKASVRGMDRATADYV
GMLATVMNALALQSALERAGVPCVVQSAIEMKNVAESFIRLKARSYLDNNKIVIFAAGTGNPFFSTDTTAALRASEINAE
VVMKATSVDGVYDADPKKVSGAKRFDTISYQECLERQLKVMDSTAFTLCMDNKKPIIVFDMHTPGNITRALLGEPIGTTI
S

Sequences:

>Translated_241_residues
MSDTSAPAYRRILLKLSGEALRSPGSMDNISPEIVARIAEEIAQAHRAGVQIGLVVGGGNFWRGAKASVRGMDRATADYV
GMLATVMNALALQSALERAGVPCVVQSAIEMKNVAESFIRLKARSYLDNNKIVIFAAGTGNPFFSTDTTAALRASEINAE
VVMKATSVDGVYDADPKKVSGAKRFDTISYQECLERQLKVMDSTAFTLCMDNKKPIIVFDMHTPGNITRALLGEPIGTTI
S
>Mature_240_residues
SDTSAPAYRRILLKLSGEALRSPGSMDNISPEIVARIAEEIAQAHRAGVQIGLVVGGGNFWRGAKASVRGMDRATADYVG
MLATVMNALALQSALERAGVPCVVQSAIEMKNVAESFIRLKARSYLDNNKIVIFAAGTGNPFFSTDTTAALRASEINAEV
VMKATSVDGVYDADPKKVSGAKRFDTISYQECLERQLKVMDSTAFTLCMDNKKPIIVFDMHTPGNITRALLGEPIGTTIS

Specific function: Catalyzes the reversible phosphorylation of UMP to UDP [H]

COG id: COG0528

COG function: function code F; Uridylate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UMP kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786367, Length=241, Percent_Identity=49.792531120332, Blast_Score=236, Evalue=9e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001048
- InterPro:   IPR011817
- InterPro:   IPR015963 [H]

Pfam domain/function: PF00696 AA_kinase [H]

EC number: =2.7.4.22 [H]

Molecular weight: Translated: 25849; Mature: 25718

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTSAPAYRRILLKLSGEALRSPGSMDNISPEIVARIAEEIAQAHRAGVQIGLVVGGGN
CCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCC
FWRGAKASVRGMDRATADYVGMLATVMNALALQSALERAGVPCVVQSAIEMKNVAESFIR
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LKARSYLDNNKIVIFAAGTGNPFFSTDTTAALRASEINAEVVMKATSVDGVYDADPKKVS
HHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
GAKRFDTISYQECLERQLKVMDSTAFTLCMDNKKPIIVFDMHTPGNITRALLGEPIGTTI
CCHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCHHHHHHHCCCCCCCC
S
C
>Mature Secondary Structure 
SDTSAPAYRRILLKLSGEALRSPGSMDNISPEIVARIAEEIAQAHRAGVQIGLVVGGGN
CCCCCHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCC
FWRGAKASVRGMDRATADYVGMLATVMNALALQSALERAGVPCVVQSAIEMKNVAESFIR
CCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
LKARSYLDNNKIVIFAAGTGNPFFSTDTTAALRASEINAEVVMKATSVDGVYDADPKKVS
HHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCC
GAKRFDTISYQECLERQLKVMDSTAFTLCMDNKKPIIVFDMHTPGNITRALLGEPIGTTI
CCHHHCCCCHHHHHHHHHHHHCCCEEEEEECCCCCEEEEECCCCCHHHHHHHCCCCCCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA