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The map label for this gene is frr

Identifier: 187735811

GI number: 187735811

Start: 1596540

End: 1597106

Strand: Reverse

Name: frr

Synonym: Amuc_1318

Alternate gene names: 187735811

Gene position: 1597106-1596540 (Counterclockwise)

Preceding gene: 187735812

Following gene: 187735810

Centisome position: 59.95

GC content: 57.32

Gene sequence:

>567_bases
ATGGACGCAGAAACATTATTATTGGAAACGGAGGAATCCATGCTCAAGGCCGTGGACTTCGCCAAACAGGAATTCTCCGG
CGTACGCACGGGCAAGGCTTCCCCCGGCCTCGTGGAAAACCTGGACGTGCATGTCTCCAGCTACGGCTCCGTCATGAAAC
TGAAGGGCCTGGCCGTCATCAGCACGCCGGAACCCCGTCTCATCCTCATCCAGCCCTTTGATCCGAGCACCGTCCACGAC
ATCGGCCGCGCCATCAATGAAAGCAAGCTGAACCTTAATCCCCTGGTGGAAGGCCGTTCCATCCGCCTGCCCATTCCCGC
CCTCACGGAAGAACGCCGCAAAGACCTTGTGAAGCTTGTCAAATCCCAGGCGGAAGAAGCCCGTGTGCGCGTGCGCGGCG
CCCGGAAGGCCGCCATGGATTCCGCCAAAAAGCTCAAGGCGGAAAACATCGTTACGGAAGACGGCCAGCGCGATCTGGAA
ACGCAGATCCAGAAGCTGACGGACAAATACGTGAAGGAGATTGACGAACTGGTGGCCGTCAAGGAAAAGGATATCATGAC
CATTTAA

Upstream 100 bases:

>100_bases
CATCACGCGCGCGCTTCTCGGGGAACCGATCGGCACCACCATCAGCTGAACCCCGCATTCCTTTTCAACCCACCAAAAAC
ACTTAGCACCCACCATCATC

Downstream 100 bases:

>100_bases
CCCATCCCCAACCATTTTACGACAATGACAGACAACGTAACCAACTTCCTCGCCTCCGGCATCGAAATCAAGGGAACCAT
CCGTTTCCAGAATGACATGC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MDAETLLLETEESMLKAVDFAKQEFSGVRTGKASPGLVENLDVHVSSYGSVMKLKGLAVISTPEPRLILIQPFDPSTVHD
IGRAINESKLNLNPLVEGRSIRLPIPALTEERRKDLVKLVKSQAEEARVRVRGARKAAMDSAKKLKAENIVTEDGQRDLE
TQIQKLTDKYVKEIDELVAVKEKDIMTI

Sequences:

>Translated_188_residues
MDAETLLLETEESMLKAVDFAKQEFSGVRTGKASPGLVENLDVHVSSYGSVMKLKGLAVISTPEPRLILIQPFDPSTVHD
IGRAINESKLNLNPLVEGRSIRLPIPALTEERRKDLVKLVKSQAEEARVRVRGARKAAMDSAKKLKAENIVTEDGQRDLE
TQIQKLTDKYVKEIDELVAVKEKDIMTI
>Mature_188_residues
MDAETLLLETEESMLKAVDFAKQEFSGVRTGKASPGLVENLDVHVSSYGSVMKLKGLAVISTPEPRLILIQPFDPSTVHD
IGRAINESKLNLNPLVEGRSIRLPIPALTEERRKDLVKLVKSQAEEARVRVRGARKAAMDSAKKLKAENIVTEDGQRDLE
TQIQKLTDKYVKEIDELVAVKEKDIMTI

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=182, Percent_Identity=37.3626373626374, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI291042689, Length=137, Percent_Identity=40.1459854014599, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1786368, Length=178, Percent_Identity=41.0112359550562, Blast_Score=125, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24661488, Length=174, Percent_Identity=29.3103448275862, Blast_Score=77, Evalue=5e-15,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_AKKM8 (B2UKL9)

Other databases:

- EMBL:   CP001071
- RefSeq:   YP_001877923.1
- ProteinModelPortal:   B2UKL9
- SMR:   B2UKL9
- GeneID:   6274741
- GenomeReviews:   CP001071_GR
- KEGG:   amu:Amuc_1318
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20903; Mature: 20903

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAETLLLETEESMLKAVDFAKQEFSGVRTGKASPGLVENLDVHVSSYGSVMKLKGLAVI
CCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEHHCCCCEEEECCEEEE
STPEPRLILIQPFDPSTVHDIGRAINESKLNLNPLVEGRSIRLPIPALTEERRKDLVKLV
ECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHH
KSQAEEARVRVRGARKAAMDSAKKLKAENIVTEDGQRDLETQIQKLTDKYVKEIDELVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEKDIMTI
HCCCCCCC
>Mature Secondary Structure
MDAETLLLETEESMLKAVDFAKQEFSGVRTGKASPGLVENLDVHVSSYGSVMKLKGLAVI
CCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHEEEHHCCCCEEEECCEEEE
STPEPRLILIQPFDPSTVHDIGRAINESKLNLNPLVEGRSIRLPIPALTEERRKDLVKLV
ECCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHH
KSQAEEARVRVRGARKAAMDSAKKLKAENIVTEDGQRDLETQIQKLTDKYVKEIDELVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KEKDIMTI
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA