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The map label for this gene is cysH [H]

Identifier: 187735793

GI number: 187735793

Start: 1576655

End: 1577338

Strand: Reverse

Name: cysH [H]

Synonym: Amuc_1300

Alternate gene names: 187735793

Gene position: 1577338-1576655 (Counterclockwise)

Preceding gene: 187735794

Following gene: 187735792

Centisome position: 59.21

GC content: 51.32

Gene sequence:

>684_bases
ATGAACGCTCATTCCCCAACCGCTACAGACACGTTGCGACAAGCCGCAGCGCAATACGAAGGAAACCTTGTTTTTGCCAC
ATCATTCGGGGCAGAAGACCAAGTGCTTACCCATATGATCTCCCATCTTGGCCTGAATATTCCTCTGGCGACTCTGGACA
CGGGGCGATTATTTCCGGAAACCTATGAACTCTGGACAAGAACGGAGGAAATATACGGCATTCGCATTATTCCTTATTTT
CCGGCAGCGGAAGAAGTGGAAAGCATGATTCTGGACAAAGGTGTCAATCTGTTCCGCAACAGTGTGGAATACCGTCACGA
ATGCTGCAATATCCGTAAACTGCGCCCTCTGGAAAGACTCCTTGCCGGGAAAAAAGCGTGGATCTGCGGATTACGCTCCA
CTCAGTCCATCACCCGGAAAGGGCTTCATATCACAGAAAACGATGAGGCGAACGGCATCATCAAAATCAGCCCACTGGCC
AACTGGTCAGAAGAGGATGTCTGGAACTATATCCGCGCCTACGGCGTTCCCTACAATCCCCTTCACGATGCAGGATTCCC
CAGTATCGGGTGCGCCTGCTGCACAAGAGCTGTCAAGAGGACAGAAGATGTACGCGACGGACGATGGTGGTGGGAAGAGA
AAGAACACAAGGAGTGCGGTCTACACCGCAAACCAAGACATTGA

Upstream 100 bases:

>100_bases
CCGATTCAGCGGATCGGTACTACTCAACTCCTCTGTTCATCTGACATCCCGTTCTTTTCTACCGGATACGGCTATCCACC
TTCAACCAGCGCCAACATTC

Downstream 100 bases:

>100_bases
TAACCAAAAATATACAAAATGAACAGCATTTACAGACTCAGCCAGCTAAAACAGTTGGAGGCAGAAAGCATTCACATTTT
CCGGGATGCCATCAGCCAGT

Product: adenylylsulfate reductase, thioredoxin dependent

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MNAHSPTATDTLRQAAAQYEGNLVFATSFGAEDQVLTHMISHLGLNIPLATLDTGRLFPETYELWTRTEEIYGIRIIPYF
PAAEEVESMILDKGVNLFRNSVEYRHECCNIRKLRPLERLLAGKKAWICGLRSTQSITRKGLHITENDEANGIIKISPLA
NWSEEDVWNYIRAYGVPYNPLHDAGFPSIGCACCTRAVKRTEDVRDGRWWWEEKEHKECGLHRKPRH

Sequences:

>Translated_227_residues
MNAHSPTATDTLRQAAAQYEGNLVFATSFGAEDQVLTHMISHLGLNIPLATLDTGRLFPETYELWTRTEEIYGIRIIPYF
PAAEEVESMILDKGVNLFRNSVEYRHECCNIRKLRPLERLLAGKKAWICGLRSTQSITRKGLHITENDEANGIIKISPLA
NWSEEDVWNYIRAYGVPYNPLHDAGFPSIGCACCTRAVKRTEDVRDGRWWWEEKEHKECGLHRKPRH
>Mature_227_residues
MNAHSPTATDTLRQAAAQYEGNLVFATSFGAEDQVLTHMISHLGLNIPLATLDTGRLFPETYELWTRTEEIYGIRIIPYF
PAAEEVESMILDKGVNLFRNSVEYRHECCNIRKLRPLERLLAGKKAWICGLRSTQSITRKGLHITENDEANGIIKISPLA
NWSEEDVWNYIRAYGVPYNPLHDAGFPSIGCACCTRAVKRTEDVRDGRWWWEEKEHKECGLHRKPRH

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=204, Percent_Identity=28.4313725490196, Blast_Score=90, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6325425, Length=214, Percent_Identity=35.5140186915888, Blast_Score=95, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 26025; Mature: 26025

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAHSPTATDTLRQAAAQYEGNLVFATSFGAEDQVLTHMISHLGLNIPLATLDTGRLFPE
CCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCHH
TYELWTRTEEIYGIRIIPYFPAAEEVESMILDKGVNLFRNSVEYRHECCNIRKLRPLERL
HHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHH
LAGKKAWICGLRSTQSITRKGLHITENDEANGIIKISPLANWSEEDVWNYIRAYGVPYNP
HCCCHHEEECCCCHHHHHHCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCC
LHDAGFPSIGCACCTRAVKRTEDVRDGRWWWEEKEHKECGLHRKPRH
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MNAHSPTATDTLRQAAAQYEGNLVFATSFGAEDQVLTHMISHLGLNIPLATLDTGRLFPE
CCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCCCCHH
TYELWTRTEEIYGIRIIPYFPAAEEVESMILDKGVNLFRNSVEYRHECCNIRKLRPLERL
HHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHH
LAGKKAWICGLRSTQSITRKGLHITENDEANGIIKISPLANWSEEDVWNYIRAYGVPYNP
HCCCHHEEECCCCHHHHHHCCCEEECCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCC
LHDAGFPSIGCACCTRAVKRTEDVRDGRWWWEEKEHKECGLHRKPRH
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10464198; 11481430 [H]