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The map label for this gene is pdxH [H]

Identifier: 187735756

GI number: 187735756

Start: 1523144

End: 1523782

Strand: Reverse

Name: pdxH [H]

Synonym: Amuc_1262

Alternate gene names: 187735756

Gene position: 1523782-1523144 (Counterclockwise)

Preceding gene: 187735757

Following gene: 187735755

Centisome position: 57.2

GC content: 52.11

Gene sequence:

>639_bases
ATGGACTTGTCCAATTTCAGAGAAGAATACCTCAAAGGCCAGCTGCACAGAAAGGACCTGGCGGAAAATCCCTTTGAACA
ATTCCAAACCTGGTTTGAACAGGCCCTGAAAGCGGATATTCCGGAACCCAACGCTTTTTCCCTGGCCACGGCGGACGCCC
AGGGCAGGCCCTCCCTGCGCACCGTGCTGCTCAAATATTTTGACCGGACGGGCTTTGTTTTCTTCACCAACTACGGCAGC
CACAAGGCCCGCGATATTGAAGAAAATCCGCAGGTCTGCATGATGCTTCCGTGGGTAATGCTGGAACGCCAGATCATCAT
TTACGGAAAAGCCGTCAAAGTCTCCCGCGCGGAATCCCTGAAATATTTCCTCACCCGCCCCAAGGAATCCCAGCTTGGAG
CTTGGGTTTCACACCAAAGCTCCGTCATTTCCGGAAGAAAACTGTTGGAAATGAAGTTGATGGAACTGAAAAACAAATTC
TCCAAAGGAGAAATACCCCTTCCCTCCTTCTGGGGCGGCTACCGAATTATCCCGGATACCTTTGAATTCTGGCAGGGCGG
CCCCGGCCGCGTGCATGACCGTTTCATGTACAAACTTCAGGAAAACGGCTCCTGGACAATTGAACGCCTTCAGCCATGA

Upstream 100 bases:

>100_bases
CGTGGACTTCGTCTCCGTAGGCTACGTGACCCACTCGGCCCCCTCCCTGGACCTGGGGCTGGATTTCAGCGTAGAATAAC
CACTCATCGTTCAACACGCC

Downstream 100 bases:

>100_bases
CCGTCCGGCGCACAACAAACCAGGGGCTTTCTTTCCTGGACGTAACAACACCGCTCTGCACGGCATCCCTGTGCCTTCAG
GGAGCGCACCTCACCTCATG

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MDLSNFREEYLKGQLHRKDLAENPFEQFQTWFEQALKADIPEPNAFSLATADAQGRPSLRTVLLKYFDRTGFVFFTNYGS
HKARDIEENPQVCMMLPWVMLERQIIIYGKAVKVSRAESLKYFLTRPKESQLGAWVSHQSSVISGRKLLEMKLMELKNKF
SKGEIPLPSFWGGYRIIPDTFEFWQGGPGRVHDRFMYKLQENGSWTIERLQP

Sequences:

>Translated_212_residues
MDLSNFREEYLKGQLHRKDLAENPFEQFQTWFEQALKADIPEPNAFSLATADAQGRPSLRTVLLKYFDRTGFVFFTNYGS
HKARDIEENPQVCMMLPWVMLERQIIIYGKAVKVSRAESLKYFLTRPKESQLGAWVSHQSSVISGRKLLEMKLMELKNKF
SKGEIPLPSFWGGYRIIPDTFEFWQGGPGRVHDRFMYKLQENGSWTIERLQP
>Mature_212_residues
MDLSNFREEYLKGQLHRKDLAENPFEQFQTWFEQALKADIPEPNAFSLATADAQGRPSLRTVLLKYFDRTGFVFFTNYGS
HKARDIEENPQVCMMLPWVMLERQIIIYGKAVKVSRAESLKYFLTRPKESQLGAWVSHQSSVISGRKLLEMKLMELKNKF
SKGEIPLPSFWGGYRIIPDTFEFWQGGPGRVHDRFMYKLQENGSWTIERLQP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=204, Percent_Identity=42.156862745098, Blast_Score=160, Evalue=7e-40,
Organism=Escherichia coli, GI1787926, Length=210, Percent_Identity=51.9047619047619, Blast_Score=240, Evalue=5e-65,
Organism=Caenorhabditis elegans, GI17553712, Length=222, Percent_Identity=39.1891891891892, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6319509, Length=210, Percent_Identity=41.4285714285714, Blast_Score=158, Evalue=5e-40,
Organism=Drosophila melanogaster, GI45551845, Length=207, Percent_Identity=46.3768115942029, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24644901, Length=207, Percent_Identity=46.3768115942029, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24644903, Length=176, Percent_Identity=27.8409090909091, Blast_Score=73, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24791; Mature: 24791

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSNFREEYLKGQLHRKDLAENPFEQFQTWFEQALKADIPEPNAFSLATADAQGRPSLR
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHH
TVLLKYFDRTGFVFFTNYGSHKARDIEENPQVCMMLPWVMLERQIIIYGKAVKVSRAESL
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHHHHCCEEEEEECEEEHHHHHHH
KYFLTRPKESQLGAWVSHQSSVISGRKLLEMKLMELKNKFSKGEIPLPSFWGGYRIIPDT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCC
FEFWQGGPGRVHDRFMYKLQENGSWTIERLQP
HHHHCCCCCCHHHHHHHEECCCCCEEEEECCC
>Mature Secondary Structure
MDLSNFREEYLKGQLHRKDLAENPFEQFQTWFEQALKADIPEPNAFSLATADAQGRPSLR
CCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCHHHH
TVLLKYFDRTGFVFFTNYGSHKARDIEENPQVCMMLPWVMLERQIIIYGKAVKVSRAESL
HHHHHHHCCCCEEEEECCCCCCCCCCCCCCCEEEEHHHHHHCCEEEEEECEEEHHHHHHH
KYFLTRPKESQLGAWVSHQSSVISGRKLLEMKLMELKNKFSKGEIPLPSFWGGYRIIPDT
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCC
FEFWQGGPGRVHDRFMYKLQENGSWTIERLQP
HHHHCCCCCCHHHHHHHEECCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA