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The map label for this gene is yeaD [H]

Identifier: 187735755

GI number: 187735755

Start: 1522293

End: 1523147

Strand: Reverse

Name: yeaD [H]

Synonym: Amuc_1261

Alternate gene names: 187735755

Gene position: 1523147-1522293 (Counterclockwise)

Preceding gene: 187735756

Following gene: 187735752

Centisome position: 57.17

GC content: 60.0

Gene sequence:

>855_bases
ATGACCGTCCGGCGCACAACAAACCAGGGGCTTTCTTTCCTGGACGTAACAACACCGCTCTGCACGGCATCCCTGTGCCT
TCAGGGAGCGCACCTCACCTCATGGAAGCCGGCAGGGCATGAGGAATGCCTTTTTCTTTCTCCTAACGCAGCCTTTGTCC
CCGGCAAAGCCATCCGCGGAGGCATCCCCGTCTGCTGGCCCTGGTTCGGCCCCCGGGAAGGAGCACCGTCCCACGGCATA
GCGCGCACCTCGGAATGGCGCCTCCACCACCAGGAAATGGACAAGTGCGGCAACGTCCTGCTCTCCCTGGCTTTCTATCC
GGAAGATGAATCCTATCCCGCCGCCATCCTGCGCCTTACCCTGGGCCGCACGCTGGCCATGAGGCTGGAAACCACGGCGC
GCACGCAGCCCTGCAAGCTCACGGAAGCATTCCATAACTACTTTGCCGTCGGCAACCTGACCAAATGCCGCGTTCATGGG
CTGGAGGACATCCCGTTCCGGGAAGAAGCCGCCCAGCCCATGAAGCACGGAGAACGCCCGCTGACGCCGCTGGGGTGCTT
GGACCGCGTTTACAACTTCCCCTCCTGTTCGGGAAAAACAATGCTGGAAGACCTCATGCTGAACCGCGCCATCACGGTGG
AGCGGAACCATGCCTCTTCCGTCATCGTCTGGAATCCTGGACAACAGGGCGCCAAAAACATGGCGGACCTGGGTGCGGAG
TCCTGGAATAAATTCCTGTGCATTGAAACGGGAAACGCGGAGCCCCGTTCCATTTCCCTCGCTCCCGGACAAACCCATAC
CCTTTACCAAAAAATTTCCGTAAGGCATATGGAGGAAGCCTGCTCTCCCCGTTAA

Upstream 100 bases:

>100_bases
ATACCTTTGAATTCTGGCAGGGCGGCCCCGGCCGCGTGCATGACCGTTTCATGTACAAACTTCAGGAAAACGGCTCCTGG
ACAATTGAACGCCTTCAGCC

Downstream 100 bases:

>100_bases
AACGGCAGACAGCATTACCTCTCAAGTAATGTTCCGGAACATTGCCTTGCCGCCCTTCCGGAATTTCCTTTGTCACCCTT
GCCTCTCAGGCCGCCTCCAA

Product: Aldose 1-epimerase

Products: NA

Alternate protein names: Putative D-hexose-6-phosphate mutarotase; Unknown protein from 2D-page spots T26/PR37 [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTVRRTTNQGLSFLDVTTPLCTASLCLQGAHLTSWKPAGHEECLFLSPNAAFVPGKAIRGGIPVCWPWFGPREGAPSHGI
ARTSEWRLHHQEMDKCGNVLLSLAFYPEDESYPAAILRLTLGRTLAMRLETTARTQPCKLTEAFHNYFAVGNLTKCRVHG
LEDIPFREEAAQPMKHGERPLTPLGCLDRVYNFPSCSGKTMLEDLMLNRAITVERNHASSVIVWNPGQQGAKNMADLGAE
SWNKFLCIETGNAEPRSISLAPGQTHTLYQKISVRHMEEACSPR

Sequences:

>Translated_284_residues
MTVRRTTNQGLSFLDVTTPLCTASLCLQGAHLTSWKPAGHEECLFLSPNAAFVPGKAIRGGIPVCWPWFGPREGAPSHGI
ARTSEWRLHHQEMDKCGNVLLSLAFYPEDESYPAAILRLTLGRTLAMRLETTARTQPCKLTEAFHNYFAVGNLTKCRVHG
LEDIPFREEAAQPMKHGERPLTPLGCLDRVYNFPSCSGKTMLEDLMLNRAITVERNHASSVIVWNPGQQGAKNMADLGAE
SWNKFLCIETGNAEPRSISLAPGQTHTLYQKISVRHMEEACSPR
>Mature_283_residues
TVRRTTNQGLSFLDVTTPLCTASLCLQGAHLTSWKPAGHEECLFLSPNAAFVPGKAIRGGIPVCWPWFGPREGAPSHGIA
RTSEWRLHHQEMDKCGNVLLSLAFYPEDESYPAAILRLTLGRTLAMRLETTARTQPCKLTEAFHNYFAVGNLTKCRVHGL
EDIPFREEAAQPMKHGERPLTPLGCLDRVYNFPSCSGKTMLEDLMLNRAITVERNHASSVIVWNPGQQGAKNMADLGAES
WNKFLCIETGNAEPRSISLAPGQTHTLYQKISVRHMEEACSPR

Specific function: Unknown

COG id: COG0676

COG function: function code G; Uncharacterized enzymes related to aldose 1-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Glucose-6-phosphate 1-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI87081973, Length=263, Percent_Identity=38.4030418250951, Blast_Score=154, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6323746, Length=263, Percent_Identity=27.3764258555133, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19921284, Length=266, Percent_Identity=25.5639097744361, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008183
- InterPro:   IPR011013
- InterPro:   IPR014718 [H]

Pfam domain/function: PF01263 Aldose_epim [H]

EC number: =5.1.3.15 [H]

Molecular weight: Translated: 31512; Mature: 31381

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRRTTNQGLSFLDVTTPLCTASLCLQGAHLTSWKPAGHEECLFLSPNAAFVPGKAIRG
CCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHC
GIPVCWPWFGPREGAPSHGIARTSEWRLHHQEMDKCGNVLLSLAFYPEDESYPAAILRLT
CCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHH
LGRTLAMRLETTARTQPCKLTEAFHNYFAVGNLTKCRVHGLEDIPFREEAAQPMKHGERP
HHHHEEEEEHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCC
LTPLGCLDRVYNFPSCSGKTMLEDLMLNRAITVERNHASSVIVWNPGQQGAKNMADLGAE
CCHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCCEEEEECCCCHHHHHHHHHCHH
SWNKFLCIETGNAEPRSISLAPGQTHTLYQKISVRHMEEACSPR
CCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVRRTTNQGLSFLDVTTPLCTASLCLQGAHLTSWKPAGHEECLFLSPNAAFVPGKAIRG
CCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHC
GIPVCWPWFGPREGAPSHGIARTSEWRLHHQEMDKCGNVLLSLAFYPEDESYPAAILRLT
CCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHH
LGRTLAMRLETTARTQPCKLTEAFHNYFAVGNLTKCRVHGLEDIPFREEAAQPMKHGERP
HHHHEEEEEHHCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHCCCCC
LTPLGCLDRVYNFPSCSGKTMLEDLMLNRAITVERNHASSVIVWNPGQQGAKNMADLGAE
CCHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEECCCCCEEEEECCCCHHHHHHHHHCHH
SWNKFLCIETGNAEPRSISLAPGQTHTLYQKISVRHMEEACSPR
CCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9298646; 10493123 [H]