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The map label for this gene is ubiE [C]

Identifier: 187735562

GI number: 187735562

Start: 1273673

End: 1274590

Strand: Reverse

Name: ubiE [C]

Synonym: Amuc_1067

Alternate gene names: 187735562

Gene position: 1274590-1273673 (Counterclockwise)

Preceding gene: 187735565

Following gene: 187735560

Centisome position: 47.84

GC content: 60.24

Gene sequence:

>918_bases
ATGAAGTCAACCCTAAAAACGCTCAAACTCCTGGCAGATCCCACCCGCCTGCGCATCATCAACGTTCTGAATGAAGAATC
CCTGAGCGTCGCGGAACTTCAGGAAATTCTCGGCATGGGGCAAAGCCGCATCTCCACCCAGCTGGCCCAGCTCCGGCAGG
AAGGGGTGGTGGAGGACGCCCGTTCCGGCAAAAATGTCTTTTACACTCTTTCCCTGGCAGGCGATCTGCACAACGTAGCC
CTGAAAGCCTGCGAGGAATTGCCGGAGGCGGAAACGGACCAAAAAGCCCTTCAGGTTATCCTGGACAAGCGCAAAAACCG
CACCCAGGCCTATTTTGACGAAGTAGTGTGCCGTCTGGGCAAGAACTACGCGCCAGGCCGTTCCTGGAAAGCGCTGGCCG
GAGCACTGCTCCGCATTCTGAACTATGACGTAGTGGCGGACCTGGGAGCCGGGGAAGGTTTCGTTTCCCAGCTCATCTCC
CCCAGCGCCAAACAGGTGATCGCCGTGGATAACTCCCCCAGCATGGTGGAGCTGGGGCAGGAGCTGGCGCGCAAACACGG
GCTGGACAATCTGGAATACCGCCTGGGCGACATCGAAGCGCCGCCCATTAAACCCGGCACGGTGGATCTGGCCCTGCTCA
GCCAGGCCCTGCACCATGCGCAAAAACCGTCCAGAGCGCTGGAAGCTGCGTGGGATATCCTGAAATCCGGCGGTTGCCTG
GTGGTGCTGGATCTGCTCCAGCATGGACAGGAGGAAGCCCGTGAACTTTACGCGGACCGCTGGCTGGGCTTCACGCCCGC
CGCCCTGGAAAGCATGCTGAAGGAAGCGGGATTCCGGAACATCCACACGGATATTGTGGACAGGGAGCCGGACCCGCCCC
ATTTCCAGACTCTGATGGCCGCCGCCTGGAAACCCTGA

Upstream 100 bases:

>100_bases
CTTGTCCGGATGGCCTTCTCCAACGGATTCCGACGTAAAGATGTGAGGGGTGTTTCTGCTCATATCGATAAATCTCGATG
TGTTGATATATTATTCCGCT

Downstream 100 bases:

>100_bases
CGTACAGCCGTCTTAATCCATTTTCCTTCCGGAATAGCCGGAGCGGACTTCCGGCATGCCTCCACAAGATTCCTCACGGT
ACCGGCATGCCATCCATGAA

Product: ArsR family transcriptional regulator

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Transcriptional Regulator ArsR Family; Methyltransferase Type; SAM-Dependent Methyltransferase; Transcriptional Regulator; Methyltransferase Domain Family; ArsR Family Regulatory Protein; Transcriptional Regulator Arsr Family; Arsenite S-Adenosylmethyltransferase; ArsR-Family Transcriptional Regulator; Methyltransferase; ArsR Domain Proteni; Transcriptional Regulator ArsR Family/Methyltransferase; Regulatory Protein; Methyltransferase Domain Protein; UbiE/COQ5 Family Methlytransferase; ArsR Family Methyltransferase Transcriptional Regulator; Ribosomal Methyltransferase; Methyltransferase Transcriptional Regulator Protein; Transcriptional Regulator Transcription Regulator Protein; Methyltransferase Domain Family Protein

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKSTLKTLKLLADPTRLRIINVLNEESLSVAELQEILGMGQSRISTQLAQLRQEGVVEDARSGKNVFYTLSLAGDLHNVA
LKACEELPEAETDQKALQVILDKRKNRTQAYFDEVVCRLGKNYAPGRSWKALAGALLRILNYDVVADLGAGEGFVSQLIS
PSAKQVIAVDNSPSMVELGQELARKHGLDNLEYRLGDIEAPPIKPGTVDLALLSQALHHAQKPSRALEAAWDILKSGGCL
VVLDLLQHGQEEARELYADRWLGFTPAALESMLKEAGFRNIHTDIVDREPDPPHFQTLMAAAWKP

Sequences:

>Translated_305_residues
MKSTLKTLKLLADPTRLRIINVLNEESLSVAELQEILGMGQSRISTQLAQLRQEGVVEDARSGKNVFYTLSLAGDLHNVA
LKACEELPEAETDQKALQVILDKRKNRTQAYFDEVVCRLGKNYAPGRSWKALAGALLRILNYDVVADLGAGEGFVSQLIS
PSAKQVIAVDNSPSMVELGQELARKHGLDNLEYRLGDIEAPPIKPGTVDLALLSQALHHAQKPSRALEAAWDILKSGGCL
VVLDLLQHGQEEARELYADRWLGFTPAALESMLKEAGFRNIHTDIVDREPDPPHFQTLMAAAWKP
>Mature_305_residues
MKSTLKTLKLLADPTRLRIINVLNEESLSVAELQEILGMGQSRISTQLAQLRQEGVVEDARSGKNVFYTLSLAGDLHNVA
LKACEELPEAETDQKALQVILDKRKNRTQAYFDEVVCRLGKNYAPGRSWKALAGALLRILNYDVVADLGAGEGFVSQLIS
PSAKQVIAVDNSPSMVELGQELARKHGLDNLEYRLGDIEAPPIKPGTVDLALLSQALHHAQKPSRALEAAWDILKSGGCL
VVLDLLQHGQEEARELYADRWLGFTPAALESMLKEAGFRNIHTDIVDREPDPPHFQTLMAAAWKP

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33574; Mature: 33574

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTLKTLKLLADPTRLRIINVLNEESLSVAELQEILGMGQSRISTQLAQLRQEGVVEDA
CCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
RSGKNVFYTLSLAGDLHNVALKACEELPEAETDQKALQVILDKRKNRTQAYFDEVVCRLG
CCCCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
KNYAPGRSWKALAGALLRILNYDVVADLGAGEGFVSQLISPSAKQVIAVDNSPSMVELGQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHH
ELARKHGLDNLEYRLGDIEAPPIKPGTVDLALLSQALHHAQKPSRALEAAWDILKSGGCL
HHHHHCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHH
VVLDLLQHGQEEARELYADRWLGFTPAALESMLKEAGFRNIHTDIVDREPDPPHFQTLMA
HHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHH
AAWKP
HHCCC
>Mature Secondary Structure
MKSTLKTLKLLADPTRLRIINVLNEESLSVAELQEILGMGQSRISTQLAQLRQEGVVEDA
CCHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCHHHH
RSGKNVFYTLSLAGDLHNVALKACEELPEAETDQKALQVILDKRKNRTQAYFDEVVCRLG
CCCCCEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
KNYAPGRSWKALAGALLRILNYDVVADLGAGEGFVSQLISPSAKQVIAVDNSPSMVELGQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEECCCCCHHHHHH
ELARKHGLDNLEYRLGDIEAPPIKPGTVDLALLSQALHHAQKPSRALEAAWDILKSGGCL
HHHHHCCCCCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCHH
VVLDLLQHGQEEARELYADRWLGFTPAALESMLKEAGFRNIHTDIVDREPDPPHFQTLMA
HHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHH
AAWKP
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA