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The map label for this gene is cysS [H]

Identifier: 187735526

GI number: 187735526

Start: 1223090

End: 1224505

Strand: Reverse

Name: cysS [H]

Synonym: Amuc_1031

Alternate gene names: 187735526

Gene position: 1224505-1223090 (Counterclockwise)

Preceding gene: 187735527

Following gene: 187735525

Centisome position: 45.96

GC content: 58.69

Gene sequence:

>1416_bases
ATGTTACACCTTTACGATACCCGCACCAGAACGGCCCAGGACATTTCTCCCATGGATGGAAAAACACTGCGCTTTTACTG
TTGCGGCCCCACGGTGTACGGCCCTACCCACATCGGCAATTTCCGCACTTTCGTGATGCAGGACGTCTTCCGCCGCGTCC
TGGAACTGGGGGGGGTGCCCACCACGCATATCCGCAATCTGACGGATGTGGACGACAAAACTATCCGGGATTCTCAAAAG
GCTGGCGTTTCTCTGGCGGAATTCACCGCAGGCTGGGCGGATCTGTTCCACCGGGACTGTGCCGCCCTTAATTGCCTGCC
TCCCCATGCGGAACCCTCCGCCGTGGGCCATATTCCCGAACAAATACGGATGGTTCAAACACTGGTGGAAAAGGGCCATG
CCTATGTATCGGAAGACGGTTCCGTGTATTTCAGAATTTCTTCCTTCCCGGAATACGGAAGGCTTTCCCACCTGGACGAA
CGTGAACTGGATTTAGGAAAAACCGCCAATACCCGGTCCAACGCAGACGAATATGAAAAAGACTCCGTGGCAGACTTCGT
GCTGTGGAAGAGCCGCAGGCCGGAAGACGGAAACAACTTCTGGCCCTCTCCCTGGGGAGAAGGCCGCCCCGGCTGGCACC
TGGAATGCTCCGCCATGATCCATAAATACTTCGGCAATGACTTTGATCTCCACTCCGGCGGCGTGGATCTGGTATTCCCC
CACCATGAAAACGAAGTGGCCCAGTCCCGCTGCGCCTGCGGCGGCGGCTTCGCGCGCCTGTGGTTCCACATCACGCACCT
GCTGGTGGACGGAGGCAAGATGTCCAAATCCCTGGGCAACATGTACACGCTGGCGGATTTGGACAAACTGGGCCACAGGC
CGTCCGCGGTCCGGTACGTGCTGGCGGGGGGCTATTACCGCCGTCCGTTGAATTTCACCCTTTCCTCTCTGGAAGACGCT
AAAGCCGCGCTGAACCGCCTGTCCAAATTCGATATGCAGCTCAGGAACGCCTCCGGAACGGATTCCGTTCCCTCCTATGA
GGAATTCTGCGCGGCATTCCCGGAATTGGGAATTTTCCAGCCGGCATGGGACAGCCTGAACGATGACCTAAACACTCCGG
AAGCCCTGGGCCATGTTTTCAGCGCCATCAGGAAGGCGGATATCCCCTCCCTTTCACCGGAGGAGGCGGCCCGCCTGCGG
AATGCCTTCCACTTTATTCTGGCCGCCTTCGGCATTATTCTGCCGGAGGAGGGACAGGAGGAAGCCCCGGAAGAAATCCG
CACCCTGGCGGATCAGCGCTGGCAGGCCAAGCAGAACCGGGACTGGACGGAAGCCGACCGCCTGAGGGCGGAAGTGGCAG
CGCTGGGCTGGGTCATTAAAGACCGCAAGGACGGATACGACCTGGCACGCAAATAA

Upstream 100 bases:

>100_bases
CCTCTGATTTCTTCAAAGCCGGGGACGCGGACAACCGCGGATCCCCGGCTTTCTTTTCCCGCTTGACCGGGAAGCCCTCT
TCCCTTCTAATCGTTCCGCC

Downstream 100 bases:

>100_bases
ACAAATGGACGCCTTTTCCTCTATTCCCAATCATACGGGCTTCACGGCCAGGAACCTGTTCATGGACAGGCAGGAAATCC
TGAGAGGCGGAGCCTTCGCC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MLHLYDTRTRTAQDISPMDGKTLRFYCCGPTVYGPTHIGNFRTFVMQDVFRRVLELGGVPTTHIRNLTDVDDKTIRDSQK
AGVSLAEFTAGWADLFHRDCAALNCLPPHAEPSAVGHIPEQIRMVQTLVEKGHAYVSEDGSVYFRISSFPEYGRLSHLDE
RELDLGKTANTRSNADEYEKDSVADFVLWKSRRPEDGNNFWPSPWGEGRPGWHLECSAMIHKYFGNDFDLHSGGVDLVFP
HHENEVAQSRCACGGGFARLWFHITHLLVDGGKMSKSLGNMYTLADLDKLGHRPSAVRYVLAGGYYRRPLNFTLSSLEDA
KAALNRLSKFDMQLRNASGTDSVPSYEEFCAAFPELGIFQPAWDSLNDDLNTPEALGHVFSAIRKADIPSLSPEEAARLR
NAFHFILAAFGIILPEEGQEEAPEEIRTLADQRWQAKQNRDWTEADRLRAEVAALGWVIKDRKDGYDLARK

Sequences:

>Translated_471_residues
MLHLYDTRTRTAQDISPMDGKTLRFYCCGPTVYGPTHIGNFRTFVMQDVFRRVLELGGVPTTHIRNLTDVDDKTIRDSQK
AGVSLAEFTAGWADLFHRDCAALNCLPPHAEPSAVGHIPEQIRMVQTLVEKGHAYVSEDGSVYFRISSFPEYGRLSHLDE
RELDLGKTANTRSNADEYEKDSVADFVLWKSRRPEDGNNFWPSPWGEGRPGWHLECSAMIHKYFGNDFDLHSGGVDLVFP
HHENEVAQSRCACGGGFARLWFHITHLLVDGGKMSKSLGNMYTLADLDKLGHRPSAVRYVLAGGYYRRPLNFTLSSLEDA
KAALNRLSKFDMQLRNASGTDSVPSYEEFCAAFPELGIFQPAWDSLNDDLNTPEALGHVFSAIRKADIPSLSPEEAARLR
NAFHFILAAFGIILPEEGQEEAPEEIRTLADQRWQAKQNRDWTEADRLRAEVAALGWVIKDRKDGYDLARK
>Mature_471_residues
MLHLYDTRTRTAQDISPMDGKTLRFYCCGPTVYGPTHIGNFRTFVMQDVFRRVLELGGVPTTHIRNLTDVDDKTIRDSQK
AGVSLAEFTAGWADLFHRDCAALNCLPPHAEPSAVGHIPEQIRMVQTLVEKGHAYVSEDGSVYFRISSFPEYGRLSHLDE
RELDLGKTANTRSNADEYEKDSVADFVLWKSRRPEDGNNFWPSPWGEGRPGWHLECSAMIHKYFGNDFDLHSGGVDLVFP
HHENEVAQSRCACGGGFARLWFHITHLLVDGGKMSKSLGNMYTLADLDKLGHRPSAVRYVLAGGYYRRPLNFTLSSLEDA
KAALNRLSKFDMQLRNASGTDSVPSYEEFCAAFPELGIFQPAWDSLNDDLNTPEALGHVFSAIRKADIPSLSPEEAARLR
NAFHFILAAFGIILPEEGQEEAPEEIRTLADQRWQAKQNRDWTEADRLRAEVAALGWVIKDRKDGYDLARK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=324, Percent_Identity=34.2592592592593, Blast_Score=199, Evalue=6e-51,
Organism=Homo sapiens, GI10835051, Length=259, Percent_Identity=38.6100386100386, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI62240992, Length=259, Percent_Identity=38.6100386100386, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI21269877, Length=259, Percent_Identity=38.6100386100386, Blast_Score=168, Evalue=1e-41,
Organism=Homo sapiens, GI303304987, Length=259, Percent_Identity=38.6100386100386, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI1786737, Length=485, Percent_Identity=38.5567010309278, Blast_Score=300, Evalue=1e-82,
Organism=Caenorhabditis elegans, GI17509797, Length=239, Percent_Identity=35.9832635983264, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17509795, Length=239, Percent_Identity=35.9832635983264, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6324082, Length=317, Percent_Identity=33.4384858044164, Blast_Score=171, Evalue=3e-43,
Organism=Drosophila melanogaster, GI19922218, Length=339, Percent_Identity=33.9233038348083, Blast_Score=193, Evalue=2e-49,
Organism=Drosophila melanogaster, GI19922364, Length=261, Percent_Identity=36.3984674329502, Blast_Score=166, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53023; Mature: 53023

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHLYDTRTRTAQDISPMDGKTLRFYCCGPTVYGPTHIGNFRTFVMQDVFRRVLELGGVP
CEEEECCCCCCHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
TTHIRNLTDVDDKTIRDSQKAGVSLAEFTAGWADLFHRDCAALNCLPPHAEPSAVGHIPE
HHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHH
QIRMVQTLVEKGHAYVSEDGSVYFRISSFPEYGRLSHLDERELDLGKTANTRSNADEYEK
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHH
DSVADFVLWKSRRPEDGNNFWPSPWGEGRPGWHLECSAMIHKYFGNDFDLHSGGVDLVFP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEEC
HHENEVAQSRCACGGGFARLWFHITHLLVDGGKMSKSLGNMYTLADLDKLGHRPSAVRYV
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCCEEHHHHHHHHCCCCHHHHHH
LAGGYYRRPLNFTLSSLEDAKAALNRLSKFDMQLRNASGTDSVPSYEEFCAAFPELGIFQ
HCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
PAWDSLNDDLNTPEALGHVFSAIRKADIPSLSPEEAARLRNAFHFILAAFGIILPEEGQE
CCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EAPEEIRTLADQRWQAKQNRDWTEADRLRAEVAALGWVIKDRKDGYDLARK
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC
>Mature Secondary Structure
MLHLYDTRTRTAQDISPMDGKTLRFYCCGPTVYGPTHIGNFRTFVMQDVFRRVLELGGVP
CEEEECCCCCCHHCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
TTHIRNLTDVDDKTIRDSQKAGVSLAEFTAGWADLFHRDCAALNCLPPHAEPSAVGHIPE
HHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCHH
QIRMVQTLVEKGHAYVSEDGSVYFRISSFPEYGRLSHLDERELDLGKTANTRSNADEYEK
HHHHHHHHHHCCCEEEECCCCEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHH
DSVADFVLWKSRRPEDGNNFWPSPWGEGRPGWHLECSAMIHKYFGNDFDLHSGGVDLVFP
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCEEEEEC
HHENEVAQSRCACGGGFARLWFHITHLLVDGGKMSKSLGNMYTLADLDKLGHRPSAVRYV
CCCCHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHCCEEHHHHHHHHCCCCHHHHHH
LAGGYYRRPLNFTLSSLEDAKAALNRLSKFDMQLRNASGTDSVPSYEEFCAAFPELGIFQ
HCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCC
PAWDSLNDDLNTPEALGHVFSAIRKADIPSLSPEEAARLRNAFHFILAAFGIILPEEGQE
CCHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EAPEEIRTLADQRWQAKQNRDWTEADRLRAEVAALGWVIKDRKDGYDLARK
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA