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The map label for this gene is nahA [H]

Identifier: 187735527

GI number: 187735527

Start: 1224627

End: 1226183

Strand: Reverse

Name: nahA [H]

Synonym: Amuc_1032

Alternate gene names: 187735527

Gene position: 1226183-1224627 (Counterclockwise)

Preceding gene: 187735528

Following gene: 187735526

Centisome position: 46.03

GC content: 55.43

Gene sequence:

>1557_bases
ATGAAATCAATTTTGCTAGCCGCAGCGTTCCTGGGCTCCCTCTGCTGGGCCGGAACCAATCCCTACAACATTATTCCGGA
GCCCGTCAACGTGACGACAACTTCCGGAACTACCAAAAACCTCAAAATCGTCCATGAGCAAAAAGTCGCCGGACTGGGCA
ATGAAGGGTATGCCATGAAACTAACGCCCGGCGGCGTGGAACTCCGTTATACCACGCCCAACGGGAAGGCCATGGCCATG
GCGACCCTGTTCCAGCTCCAGGACCAGCTTTCGGATACTCCTGAGGGACTTCCCTGCGGCAGCATCCAGGATTCCCCCGA
CTTCGGCTGGCGCGGCATGATGGTTGACGTAGGCCGCTACCACTATCCCATGAAGGAGATCTACAATTTTGTGGACGCCA
TGCATTATTACAAATACAACGTCCTGCATCTCCATCTGACGGAAGACCAGGGCTGGCGTCTCCCCGTTCCGGGCTACGAC
AAGCTCCGCACCATCGGCGCCGTCCGCCCCTCCGCTCCGGAAAGCCAGAACAACTCCCTGCTGGCCAATGAAGGCATGTA
TACCAAGAAGGAGCTCCAGGACCTGGTAGCCTACTGCAAAGCGCGCGGCATCCAGGTACTGCCGGAAGTGGAAATGCCGG
GTCATAACATGGCCCTGGCCGCGTCCTATCCCGAATTCTGCTGCAACACCAAACGGGCCCAGGTATGGACGCACGGCGGT
GTTTCCTCCAAGCTGATTTGCCCGCAGAAACCGGCCACTAAAAAGTTTCTTAAGGATACCTTCAATACCGTCCAGCAGAT
ATTCCCTTTCCCGTACATCCACATCGGAGGTGACGAATGCCCCATGGGGGACTGGAAGAAGTGCCCGGACTGCCAGGCCG
CCCGAGCCAAAAAGGGCCAGGGGGATAATGTGGAAGCCCAGATGAGCGATTTCACGAAAAGCCTGACGGCCATGCTCGCC
AAGCACCGGAAAAAGCCCATCCTGTGGTATGACATCAACAAGAGCTATTACCACAAGGGGGAAACCGTCATGTCCTGGCT
GCCGGGAGAATTCCCGCGTTGCATTGATAAGACGAAGGAACAGGGCATCGACCTCATCGTCACCCCCCAGTTCAAGTATT
ATCTGGCGCGTACCCAGATGAAATTCCCGGCGGACGACGTGCGCGCCCGGCCCGGTGGAGCTCCCATCCTGCTGAAAGAC
TGCTACAACTTCGATCCCCGCAACGGACGGGACAAGAATGACGTCAAGCACATCAAGGGAATCAACCTCTGCATGTGGGC
GGAATGGATTCCCTCCGGCGAATTGCTGATGTACATGACCTACCCCCGCGCCATGGCTGTTTCCGAAACCGCGTGGGGCA
GCCACAAGAACCGTCCAAGCCTGGAAGAGTTTGAAAAGAAAATGGAAACCCACAAGAAACATTTCCAGAAGCGTTTCGGC
TATACTCTGGAACGCACTGTGGAAAACAAACCCTACCGGGAAAAATTCATCACCCAAGAGGAAATCGAACGTATTAACGA
GAATTATAAAAAGGGCCAGCAAAACGCGGACAAATAG

Upstream 100 bases:

>100_bases
TCACCGTTCCTCCCGAAACACGGTTGTCCGGAACACGCCATTGACGACGGAGGAACAGGGTTTAAATCCTCACACAAACA
ACCATTACCATACGCACCGC

Downstream 100 bases:

>100_bases
CGTTTCCTTTTCTCCCGCCATCCTCTGATTTCTTCAAAGCCGGGGACGCGGACAACCGCGGATCCCCGGCTTTCTTTTCC
CGCTTGACCGGGAAGCCCTC

Product: Beta-N-acetylhexosaminidase

Products: NA

Alternate protein names: Beta-GlcNAcase; Beta-N-acetylhexosaminidase; Beta-NAHase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MKSILLAAAFLGSLCWAGTNPYNIIPEPVNVTTTSGTTKNLKIVHEQKVAGLGNEGYAMKLTPGGVELRYTTPNGKAMAM
ATLFQLQDQLSDTPEGLPCGSIQDSPDFGWRGMMVDVGRYHYPMKEIYNFVDAMHYYKYNVLHLHLTEDQGWRLPVPGYD
KLRTIGAVRPSAPESQNNSLLANEGMYTKKELQDLVAYCKARGIQVLPEVEMPGHNMALAASYPEFCCNTKRAQVWTHGG
VSSKLICPQKPATKKFLKDTFNTVQQIFPFPYIHIGGDECPMGDWKKCPDCQAARAKKGQGDNVEAQMSDFTKSLTAMLA
KHRKKPILWYDINKSYYHKGETVMSWLPGEFPRCIDKTKEQGIDLIVTPQFKYYLARTQMKFPADDVRARPGGAPILLKD
CYNFDPRNGRDKNDVKHIKGINLCMWAEWIPSGELLMYMTYPRAMAVSETAWGSHKNRPSLEEFEKKMETHKKHFQKRFG
YTLERTVENKPYREKFITQEEIERINENYKKGQQNADK

Sequences:

>Translated_518_residues
MKSILLAAAFLGSLCWAGTNPYNIIPEPVNVTTTSGTTKNLKIVHEQKVAGLGNEGYAMKLTPGGVELRYTTPNGKAMAM
ATLFQLQDQLSDTPEGLPCGSIQDSPDFGWRGMMVDVGRYHYPMKEIYNFVDAMHYYKYNVLHLHLTEDQGWRLPVPGYD
KLRTIGAVRPSAPESQNNSLLANEGMYTKKELQDLVAYCKARGIQVLPEVEMPGHNMALAASYPEFCCNTKRAQVWTHGG
VSSKLICPQKPATKKFLKDTFNTVQQIFPFPYIHIGGDECPMGDWKKCPDCQAARAKKGQGDNVEAQMSDFTKSLTAMLA
KHRKKPILWYDINKSYYHKGETVMSWLPGEFPRCIDKTKEQGIDLIVTPQFKYYLARTQMKFPADDVRARPGGAPILLKD
CYNFDPRNGRDKNDVKHIKGINLCMWAEWIPSGELLMYMTYPRAMAVSETAWGSHKNRPSLEEFEKKMETHKKHFQKRFG
YTLERTVENKPYREKFITQEEIERINENYKKGQQNADK
>Mature_518_residues
MKSILLAAAFLGSLCWAGTNPYNIIPEPVNVTTTSGTTKNLKIVHEQKVAGLGNEGYAMKLTPGGVELRYTTPNGKAMAM
ATLFQLQDQLSDTPEGLPCGSIQDSPDFGWRGMMVDVGRYHYPMKEIYNFVDAMHYYKYNVLHLHLTEDQGWRLPVPGYD
KLRTIGAVRPSAPESQNNSLLANEGMYTKKELQDLVAYCKARGIQVLPEVEMPGHNMALAASYPEFCCNTKRAQVWTHGG
VSSKLICPQKPATKKFLKDTFNTVQQIFPFPYIHIGGDECPMGDWKKCPDCQAARAKKGQGDNVEAQMSDFTKSLTAMLA
KHRKKPILWYDINKSYYHKGETVMSWLPGEFPRCIDKTKEQGIDLIVTPQFKYYLARTQMKFPADDVRARPGGAPILLKD
CYNFDPRNGRDKNDVKHIKGINLCMWAEWIPSGELLMYMTYPRAMAVSETAWGSHKNRPSLEEFEKKMETHKKHFQKRFG
YTLERTVENKPYREKFITQEEIERINENYKKGQQNADK

Specific function: Unknown

COG id: COG3525

COG function: function code G; N-acetyl-beta-hexosaminidase

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 20 family [H]

Homologues:

Organism=Homo sapiens, GI4504373, Length=431, Percent_Identity=24.1299303944316, Blast_Score=139, Evalue=9e-33,
Organism=Homo sapiens, GI189181666, Length=454, Percent_Identity=24.2290748898678, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17569815, Length=445, Percent_Identity=22.6966292134831, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17933586, Length=463, Percent_Identity=23.5421166306695, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24657468, Length=444, Percent_Identity=23.6486486486486, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17647501, Length=444, Percent_Identity=23.6486486486486, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI281365639, Length=444, Percent_Identity=23.6486486486486, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24657474, Length=444, Percent_Identity=23.6486486486486, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015882
- InterPro:   IPR001540
- InterPro:   IPR015883
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR011658 [H]

Pfam domain/function: PF00728 Glyco_hydro_20; PF02838 Glyco_hydro_20b [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 59019; Mature: 59019

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSILLAAAFLGSLCWAGTNPYNIIPEPVNVTTTSGTTKNLKIVHEQKVAGLGNEGYAMK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCEEEEEEHHHHCCCCCCEEEE
LTPGGVELRYTTPNGKAMAMATLFQLQDQLSDTPEGLPCGSIQDSPDFGWRGMMVDVGRY
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHH
HYPMKEIYNFVDAMHYYKYNVLHLHLTEDQGWRLPVPGYDKLRTIGAVRPSAPESQNNSL
CCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCE
LANEGMYTKKELQDLVAYCKARGIQVLPEVEMPGHNMALAASYPEFCCNTKRAQVWTHGG
EECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCHHHHCCCCCCEEEECCC
VSSKLICPQKPATKKFLKDTFNTVQQIFPFPYIHIGGDECPMGDWKKCPDCQAARAKKGQ
CCCCEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCC
GDNVEAQMSDFTKSLTAMLAKHRKKPILWYDINKSYYHKGETVMSWLPGEFPRCIDKTKE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCHHHHHCCCCCHHHHHHHHH
QGIDLIVTPQFKYYLARTQMKFPADDVRARPGGAPILLKDCYNFDPRNGRDKNDVKHIKG
CCCCEEECCCHHHHHHHHCCCCCHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHCC
INLCMWAEWIPSGELLMYMTYPRAMAVSETAWGSHKNRPSLEEFEKKMETHKKHFQKRFG
CCEEEEECCCCCCCEEEEEECCCHHEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
YTLERTVENKPYREKFITQEEIERINENYKKGQQNADK
CCHHHHHCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKSILLAAAFLGSLCWAGTNPYNIIPEPVNVTTTSGTTKNLKIVHEQKVAGLGNEGYAMK
CCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCEEEEEEHHHHCCCCCCEEEE
LTPGGVELRYTTPNGKAMAMATLFQLQDQLSDTPEGLPCGSIQDSPDFGWRGMMVDVGRY
ECCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEECCHH
HYPMKEIYNFVDAMHYYKYNVLHLHLTEDQGWRLPVPGYDKLRTIGAVRPSAPESQNNSL
CCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCE
LANEGMYTKKELQDLVAYCKARGIQVLPEVEMPGHNMALAASYPEFCCNTKRAQVWTHGG
EECCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCHHHHCCCCCCEEEECCC
VSSKLICPQKPATKKFLKDTFNTVQQIFPFPYIHIGGDECPMGDWKKCPDCQAARAKKGQ
CCCCEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCHHHHHCCCC
GDNVEAQMSDFTKSLTAMLAKHRKKPILWYDINKSYYHKGETVMSWLPGEFPRCIDKTKE
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHCCCHHHHHCCCCCHHHHHHHHH
QGIDLIVTPQFKYYLARTQMKFPADDVRARPGGAPILLKDCYNFDPRNGRDKNDVKHIKG
CCCCEEECCCHHHHHHHHCCCCCHHHHCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHCC
INLCMWAEWIPSGELLMYMTYPRAMAVSETAWGSHKNRPSLEEFEKKMETHKKHFQKRFG
CCEEEEECCCCCCCEEEEEECCCHHEEEHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
YTLERTVENKPYREKFITQEEIERINENYKKGQQNADK
CCHHHHHCCCCHHHHCCCHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7881557; 12949112 [H]