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The map label for this gene is pfpI [H]

Identifier: 187735447

GI number: 187735447

Start: 1127105

End: 1127668

Strand: Reverse

Name: pfpI [H]

Synonym: Amuc_0946

Alternate gene names: 187735447

Gene position: 1127668-1127105 (Counterclockwise)

Preceding gene: 187735448

Following gene: 187735445

Centisome position: 42.33

GC content: 60.82

Gene sequence:

>564_bases
ATGAAAAAAGTCGCCATACTTGCCGCCCCCGGATTTGAAGAAATCGAACTCATGGCTCCGCTGGACATCCTGCGGCGCCT
GAACATGGACGTAGTGCTTGCCGGCGTCCAGTCCGACAAGGTGGTCAGCACCCATGAAGTAACCGTCAGCACGGACACCA
TGCTGGATAAACTCCATGCTGACAAGCTGGACGCCCTGATCCTGCCCGGCGGCGCGGGCTCCTGGGTACTCCGCGACACG
CCGGAAGTCATCCATCTGGTCAAAAAAATGCATGAAGCGGGCAAGCTGGTGGCCGCCATCTGCGCCGCCCCCATCGTGCT
GGCCAAAGCGGGCCTGGTCAGGGACAGGAACGTCACGGCCTACCCGGCCCAGGACGTTTACCGGGAACTCAACGAAGCCG
GCGCCCATATTGTGAAAGATGAAAATGTGGTGCTGGACGGCAACATGCTCACCGCCAACGGCCCCGGCGCCGCCATGCTC
TTCGGCTACTCCATCGGGGAATATCTGGGGGAAGACCTCCAGGTGGCCCAGCTCAAAGAGCAGATGTGCTACACGGGCCT
GTAG

Upstream 100 bases:

>100_bases
AACCCTGCTGGAAAACCCGGTTCTTCTCCTCCTGTAGGGGTACCGGAACATGCTGCTCTTTTCCTTGAACGTTCCTCTTC
CTCCCCCTGTCTTACCAACC

Downstream 100 bases:

>100_bases
GATGCCGGCAGGCATTCCGCCTTTCCGCAGCCCCATGCGGCGCCGGAACAGCAGGGAAAGGGGGGAGAAAATTTCCCCTT
TTCACTTCATCAGGTGCCTT

Product: DJ-1 family protein

Products: NA

Alternate protein names: Intracellular protease I [H]

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKKVAILAAPGFEEIELMAPLDILRRLNMDVVLAGVQSDKVVSTHEVTVSTDTMLDKLHADKLDALILPGGAGSWVLRDT
PEVIHLVKKMHEAGKLVAAICAAPIVLAKAGLVRDRNVTAYPAQDVYRELNEAGAHIVKDENVVLDGNMLTANGPGAAML
FGYSIGEYLGEDLQVAQLKEQMCYTGL

Sequences:

>Translated_187_residues
MKKVAILAAPGFEEIELMAPLDILRRLNMDVVLAGVQSDKVVSTHEVTVSTDTMLDKLHADKLDALILPGGAGSWVLRDT
PEVIHLVKKMHEAGKLVAAICAAPIVLAKAGLVRDRNVTAYPAQDVYRELNEAGAHIVKDENVVLDGNMLTANGPGAAML
FGYSIGEYLGEDLQVAQLKEQMCYTGL
>Mature_187_residues
MKKVAILAAPGFEEIELMAPLDILRRLNMDVVLAGVQSDKVVSTHEVTVSTDTMLDKLHADKLDALILPGGAGSWVLRDT
PEVIHLVKKMHEAGKLVAAICAAPIVLAKAGLVRDRNVTAYPAQDVYRELNEAGAHIVKDENVVLDGNMLTANGPGAAML
FGYSIGEYLGEDLQVAQLKEQMCYTGL

Specific function: Thiamine biosynthesis [C]

COG id: COG0693

COG function: function code R; Putative intracellular protease/amidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PfpI endopeptidase domain [H]

Homologues:

Organism=Homo sapiens, GI183227678, Length=183, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI31543380, Length=183, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Escherichia coli, GI87081736, Length=168, Percent_Identity=33.9285714285714, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87082219, Length=156, Percent_Identity=30.7692307692308, Blast_Score=76, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17558714, Length=171, Percent_Identity=31.5789473684211, Blast_Score=88, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17531319, Length=170, Percent_Identity=37.0588235294118, Blast_Score=88, Evalue=3e-18,
Organism=Drosophila melanogaster, GI28571932, Length=183, Percent_Identity=35.5191256830601, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24653499, Length=171, Percent_Identity=36.2573099415205, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006286
- InterPro:   IPR002818 [H]

Pfam domain/function: PF01965 DJ-1_PfpI [H]

EC number: NA

Molecular weight: Translated: 20106; Mature: 20106

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVAILAAPGFEEIELMAPLDILRRLNMDVVLAGVQSDKVVSTHEVTVSTDTMLDKLHA
CCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEEHHHHHHHHHH
DKLDALILPGGAGSWVLRDTPEVIHLVKKMHEAGKLVAAICAAPIVLAKAGLVRDRNVTA
CCCCEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
YPAQDVYRELNEAGAHIVKDENVVLDGNMLTANGPGAAMLFGYSIGEYLGEDLQVAQLKE
CCHHHHHHHHHHCCCEEEECCCEEEECCEEEECCCCEEEEEHHHHHHHHCCCHHHHHHHH
QMCYTGL
HHHHCCC
>Mature Secondary Structure
MKKVAILAAPGFEEIELMAPLDILRRLNMDVVLAGVQSDKVVSTHEVTVSTDTMLDKLHA
CCCEEEEECCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCEEEEEEEEEEHHHHHHHHHH
DKLDALILPGGAGSWVLRDTPEVIHLVKKMHEAGKLVAAICAAPIVLAKAGLVRDRNVTA
CCCCEEEECCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEE
YPAQDVYRELNEAGAHIVKDENVVLDGNMLTANGPGAAMLFGYSIGEYLGEDLQVAQLKE
CCHHHHHHHHHHCCCEEEECCCEEEECCEEEECCCCEEEEEHHHHHHHHCCCHHHHHHHH
QMCYTGL
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA