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The map label for this gene is ppx [C]

Identifier: 187735438

GI number: 187735438

Start: 1114739

End: 1116295

Strand: Direct

Name: ppx [C]

Synonym: Amuc_0937

Alternate gene names: 187735438

Gene position: 1114739-1116295 (Clockwise)

Preceding gene: 187735437

Following gene: 187735439

Centisome position: 41.84

GC content: 60.5

Gene sequence:

>1557_bases
ATGATTCAAGGCGAGCAGGTTCAGGATTCGGAATTATCAACTCAGGCGGTGATCTATCTGGGCCCGAGCTCCATGAGCCT
GATGGTGGCTGAGGCTGTCCGGGACAGGATTCGCCTGCTGGATTTCCTTCAGCAGCCCGTTCCGATGGCGCGTGACATTT
TCCGGTTCCACCGCATTTCCCGGCATACCATGGACCGCTGCGTGCAAATCATCGGCGACTATCTGGAAATTCTCAAGGAA
TACGGAGCCGGCAGCAAGCTTTCCGTCCGGTTCATGATTTCCAACATCATTTCCGAGGCGGATAATGTGGACGTGTTCGT
GAACCGCATGCACGTGGCCCACGGCTTGCGGGGGCGCCGCATTGACGACGGCAAGATGACGCGCCTCATTTACGTGAAGG
TGCAGGAGGCTCTGGCCCAGTATCCGGGATTCAGCAAGAAAAAGGTGCTTGTGGTCCATACGGGGCCGGGCAATACCCGC
GTGCTTCTGTTCCAGAAGGGGCGCATCGTGCGTTATTCCTGCTACAGGCTGGGAACGCACCGCACGGGGGAGGCCGTCGG
GGAAATTGAGTACGGAGACGATGTGGCGGAGCTTTCCATTCTGCGGGAGCACATGCGCGGGCAGGTGGACCAGATTTGCC
TGGATTACGGGGGCGTGAAGGGCCTGGCGGGCCTTATCGTCATCGGCCAGGAAATGCAGCAGCTCCGGGACCGCCTGGCC
CCCACGCCGGAAGGCAAGGTGGCGTGTTCCTCCCTGGCGGCGGAGGCGGAGCGGATGTCCCGCACCACTCTGGAACAGCG
CATGAATGTTTACGGTGCGGATTTTGCCGGGGTGGACTCCCTGCTGCCCGCCGTTTTGATGACGGAAATGATTGCCCGCA
GCCTGAACCTGGATGACGTCATCATTCCCGCGAGCGGTTATGACGAGGAGTTTTCAAGCAGCCTGATACGTGCGGAACAG
CATCCGGGGGATCTGGAGGCGGAGGTTCTCCATTTCGCCGGGATTCTGGCGGACAGGTACAAGGCGGACAAAGGGCACCG
CGAGCATGTGGCGCGCCTGTGCATGGAAATGTTTGACCAGCTTCAGGACCTGCACCGCCTTTCCGAACATGACCGGCTGC
TGCTGGAAGTGGCCTCCATTCTGCATGAGGTTGGGTCTTTTATCAACCAGCAGAATCACCAGCTCCATTCCCAGTATATC
ATTCTCAACAGTGAAATCTTCGGCCTTTCCCGGGATGATGTGGAAACGATCGCCCTGCTGGCCCGCTACCACCGGCATGA
GGTTCCCGCCAATTCCGATCCCATGTACGGGGAGCTGGAATTGAGGGACCGCATGCGCGTAGCCAAGATGGCCGCCATCC
TGCGCGTGGCGGATGCCCTGGAACGCGGCCATGCCCAGCGCGTGAACGGCGTCCGGGCGCACATCCGCGGGCGCATGCTG
GAGCTGGAGCTTCAGGGCGTGCGTGAAACCGCCGTGGAAGACCTGGCCCTGCGGCTGAAGGGCGACCTGTTTGCGGATAT
CTTCGGTTATGACGTCGTGCTGGCGCCCCAGCGGTAG

Upstream 100 bases:

>100_bases
CAAATTCTTTATTCTTTCCTTTGCTGGAAGGGGCGGAAGCGGCTTTTTTGTCACGTTGCCGTTCTTGCTCCACGGCCGGG
AAACAATACATGGTATGGCA

Downstream 100 bases:

>100_bases
GCTGATTTAAAAAACTTCCATTTTCCATTTTTCCCATGTCTGACGAATATATCAACAGAGAACTTTCCTGGCTGGAATTC
AACCAGCGTGTGCTGGACCA

Product: metal dependent phosphohydrolase

Products: (polyphosphate)n-1; phosphate

Alternate protein names: Ppx/GppA Phosphatase; Ppx/Gppa Phosphatase; Ppx/GppA Phosphatase Family Protein; Metal Dependent Phosphohydrolase; Ppx/GppA Phosphatase Family; Exopolyphosphatase-Like Protein; CHAD Domain-Containing Protein; Guanosine-5-Triphosphate 3'-Diphosphatepyrophosphatase; Guanosine Pentaphosphate Phosphohydrolase; Phosphatase Ppx/GppA Family; Exopolyphosphatase Ppx; Ppx/GppA Family Phosphatase; Phosphatase Ppx/Gppa Family

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MIQGEQVQDSELSTQAVIYLGPSSMSLMVAEAVRDRIRLLDFLQQPVPMARDIFRFHRISRHTMDRCVQIIGDYLEILKE
YGAGSKLSVRFMISNIISEADNVDVFVNRMHVAHGLRGRRIDDGKMTRLIYVKVQEALAQYPGFSKKKVLVVHTGPGNTR
VLLFQKGRIVRYSCYRLGTHRTGEAVGEIEYGDDVAELSILREHMRGQVDQICLDYGGVKGLAGLIVIGQEMQQLRDRLA
PTPEGKVACSSLAAEAERMSRTTLEQRMNVYGADFAGVDSLLPAVLMTEMIARSLNLDDVIIPASGYDEEFSSSLIRAEQ
HPGDLEAEVLHFAGILADRYKADKGHREHVARLCMEMFDQLQDLHRLSEHDRLLLEVASILHEVGSFINQQNHQLHSQYI
ILNSEIFGLSRDDVETIALLARYHRHEVPANSDPMYGELELRDRMRVAKMAAILRVADALERGHAQRVNGVRAHIRGRML
ELELQGVRETAVEDLALRLKGDLFADIFGYDVVLAPQR

Sequences:

>Translated_518_residues
MIQGEQVQDSELSTQAVIYLGPSSMSLMVAEAVRDRIRLLDFLQQPVPMARDIFRFHRISRHTMDRCVQIIGDYLEILKE
YGAGSKLSVRFMISNIISEADNVDVFVNRMHVAHGLRGRRIDDGKMTRLIYVKVQEALAQYPGFSKKKVLVVHTGPGNTR
VLLFQKGRIVRYSCYRLGTHRTGEAVGEIEYGDDVAELSILREHMRGQVDQICLDYGGVKGLAGLIVIGQEMQQLRDRLA
PTPEGKVACSSLAAEAERMSRTTLEQRMNVYGADFAGVDSLLPAVLMTEMIARSLNLDDVIIPASGYDEEFSSSLIRAEQ
HPGDLEAEVLHFAGILADRYKADKGHREHVARLCMEMFDQLQDLHRLSEHDRLLLEVASILHEVGSFINQQNHQLHSQYI
ILNSEIFGLSRDDVETIALLARYHRHEVPANSDPMYGELELRDRMRVAKMAAILRVADALERGHAQRVNGVRAHIRGRML
ELELQGVRETAVEDLALRLKGDLFADIFGYDVVLAPQR
>Mature_518_residues
MIQGEQVQDSELSTQAVIYLGPSSMSLMVAEAVRDRIRLLDFLQQPVPMARDIFRFHRISRHTMDRCVQIIGDYLEILKE
YGAGSKLSVRFMISNIISEADNVDVFVNRMHVAHGLRGRRIDDGKMTRLIYVKVQEALAQYPGFSKKKVLVVHTGPGNTR
VLLFQKGRIVRYSCYRLGTHRTGEAVGEIEYGDDVAELSILREHMRGQVDQICLDYGGVKGLAGLIVIGQEMQQLRDRLA
PTPEGKVACSSLAAEAERMSRTTLEQRMNVYGADFAGVDSLLPAVLMTEMIARSLNLDDVIIPASGYDEEFSSSLIRAEQ
HPGDLEAEVLHFAGILADRYKADKGHREHVARLCMEMFDQLQDLHRLSEHDRLLLEVASILHEVGSFINQQNHQLHSQYI
ILNSEIFGLSRDDVETIALLARYHRHEVPANSDPMYGELELRDRMRVAKMAAILRVADALERGHAQRVNGVRAHIRGRML
ELELQGVRETAVEDLALRLKGDLFADIFGYDVVLAPQR

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.11

Molecular weight: Translated: 58433; Mature: 58433

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIQGEQVQDSELSTQAVIYLGPSSMSLMVAEAVRDRIRLLDFLQQPVPMARDIFRFHRIS
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RHTMDRCVQIIGDYLEILKEYGAGSKLSVRFMISNIISEADNVDVFVNRMHVAHGLRGRR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
IDDGKMTRLIYVKVQEALAQYPGFSKKKVLVVHTGPGNTRVLLFQKGRIVRYSCYRLGTH
CCCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCEEEEEHEECCCC
RTGEAVGEIEYGDDVAELSILREHMRGQVDQICLDYGGVKGLAGLIVIGQEMQQLRDRLA
CCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
PTPEGKVACSSLAAEAERMSRTTLEQRMNVYGADFAGVDSLLPAVLMTEMIARSLNLDDV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
IIPASGYDEEFSSSLIRAEQHPGDLEAEVLHFAGILADRYKADKGHREHVARLCMEMFDQ
EECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LQDLHRLSEHDRLLLEVASILHEVGSFINQQNHQLHSQYIILNSEIFGLSRDDVETIALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEEECCCCCCCCCHHHHHHHH
ARYHRHEVPANSDPMYGELELRDRMRVAKMAAILRVADALERGHAQRVNGVRAHIRGRML
HHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEE
ELELQGVRETAVEDLALRLKGDLFADIFGYDVVLAPQR
EEEHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEECCC
>Mature Secondary Structure
MIQGEQVQDSELSTQAVIYLGPSSMSLMVAEAVRDRIRLLDFLQQPVPMARDIFRFHRIS
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RHTMDRCVQIIGDYLEILKEYGAGSKLSVRFMISNIISEADNVDVFVNRMHVAHGLRGRR
HHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
IDDGKMTRLIYVKVQEALAQYPGFSKKKVLVVHTGPGNTRVLLFQKGRIVRYSCYRLGTH
CCCCCCEEEEEHHHHHHHHHCCCCCCCEEEEEEECCCCEEEEEEECCCEEEEEHEECCCC
RTGEAVGEIEYGDDVAELSILREHMRGQVDQICLDYGGVKGLAGLIVIGQEMQQLRDRLA
CCCCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCC
PTPEGKVACSSLAAEAERMSRTTLEQRMNVYGADFAGVDSLLPAVLMTEMIARSLNLDDV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCE
IIPASGYDEEFSSSLIRAEQHPGDLEAEVLHFAGILADRYKADKGHREHVARLCMEMFDQ
EECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
LQDLHRLSEHDRLLLEVASILHEVGSFINQQNHQLHSQYIILNSEIFGLSRDDVETIALL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCEEEEEECCCCCCCCCHHHHHHHH
ARYHRHEVPANSDPMYGELELRDRMRVAKMAAILRVADALERGHAQRVNGVRAHIRGRML
HHHHHHCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCEE
ELELQGVRETAVEDLALRLKGDLFADIFGYDVVLAPQR
EEEHHHHHHHHHHHHHHHHCCHHHHHHHCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (polyphosphate)n; H2O

Specific reaction: (polyphosphate)n + H2O = (polyphosphate)n-1 + phosphate

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA