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The map label for this gene is rnr [H]

Identifier: 187735416

GI number: 187735416

Start: 1091430

End: 1093700

Strand: Reverse

Name: rnr [H]

Synonym: Amuc_0915

Alternate gene names: 187735416

Gene position: 1093700-1091430 (Counterclockwise)

Preceding gene: 187735418

Following gene: 187735415

Centisome position: 41.05

GC content: 60.19

Gene sequence:

>2271_bases
ATGAATAATTCCCTTAAAGACCGCCTGATCCGTCACATGGAAGACGGACATTACGAACCTCAGAGCAAATCTGAACTGGC
TCGCGCCCTGAACGTGGATTCCCGGCAGAAGCTGGATTTCCGCGCCCTGGTGGACCAGATGGAGGAGGAAGGAAAACTCG
TGCGGCTGCAAAAGGGCAGGTACGCTTTAAAACGGGAGCGCCGGAACCTGGTGCATGGCATGATCCGCATCCTGCGCTCC
GGCAAGATTCTTTTTCTCCCCAGAAAAGGGGATCCCGCCGCTGCGGCTCTGGGATGGGACACGGAAGCCGTTCCGGAACT
GGAACTTAAACCCAACCATCTGGGCACCGCCCTGGACGGGGACCGAGTGGCCGTGCGCGTGGAACGCAAGGCAGCCAGGG
GACGGAGGAATATCCGCAGAAATCGCTTTTCTTCCCCGGATGCCGACATGAAAGCCCGCGTGGAGGAAGTGACGGAACGC
GCGCGCTCCCGATGGCTTGGCGTCTTCCGCACCGGAAAAAACAAGCCGGGCCGCGTGCTGGGGGACGGCGTAAGCTCTCC
GTCATCCATTGAACTGGCGGAAAAACCCGCCATGGAGGTGCTTCCCGGCCAACTGGTTTCCGTGGAGCCCATAACCTGCG
GTGAGGAAAAGAAAGCCCCGCGCGGGAAAATCGTGGAGGTGCTCGGCTATCCGGACGAGCCTCACGTGGACATGGAAGCC
GTTATCAGAAAATATGGCCTTTCCGTGGAATTCCCCGCCTCCGTGCTCCGGGAGCTGGAAACGCTGCCTCAAACACCTTC
CCCCGGGGAACTCGCCCGCCGGGAAGACTGGACGGACCGTACCGTCATCACCATTGACCCGGCAAGCGCCAGGGATTTTG
ACGACGCCATTTCCATCACGGCCACTCCGTCCGGCTGGACGCTGGCCGTTCACATTGCGGACGTCTCCCATTTCGTCAAG
CCCGGCGGCTCGCTGGATGGGGAAGCCCTGCGCCGCGGCAACTCTACCTACCTGCCGGACCGCGTTCTTCCGATGCTCCC
GCACCGCCTTTCCGACGATTTGTGCAGCCTGCGGCCGGATGTCGTGCGCCTGACAAAAGTATGCGAAATGAAATTTGATA
AAAAGGGGAAGATGCTCCGTGCCCGCTTTGCTGACGCTTTCATCCGCAGCAAGGCGCGCCTGACCTACCAGGAGGCCTTC
GCCATGCTGAAAGGAAACGACAAAGGGGAAGTTCCCTCCACGGTGCGGGAAGCCTGGAATCTGGCCTCCATTCTGCGCCG
CAACCGCTACGCCAAGGGAGCCCTGGATCTGGACTTCCCGGAAGTGAGAGCCGTTATGGACAAGGACGGCCGCGTGACGG
GCATCATCACGGAAGAGTACGATGAAAGCCATCAGCTCATTGAAGAGTGCATGCTGGCCGCCAACGAAGCCGTGGCCCTG
GCCCTGAAAAACGGGAACCGTCCCACCATCTACCGTGTCCACGAAGAACCGGATTCCGCCAAACTTTTTGAATTCGGCCA
GTTGTGCAGACTGTACGGGCATCCCGTGCACGATATCGACCAACGCCAGTACCTGAATGAACTGATGAAATCCATCAAGG
GTTCCCCGGACGAGCAATTGCTTAAGCTGGCGCTCCTGAAAAGCTTGATGAGGGCCAGGTACGACACGGAGCCCCTGGGC
CACTACGGCCTGGCCACCCCCAATTACTGCCACTTCACCAGCCCCATCCGCCGTTACGCGGATCTGGTGGTACACCGCTC
CCTGAATCCCCTGCTGGCCAACCCTCCCAAAGGAGCTAAAGGAGCAGGCAGTACAGGCAGGCTGGAGGAAGACGCGGAAC
ACATTTCAGAAACGGAACGCATTTCCGCCAGCGCGGAAAAGGACGCGAACCGGATGAAGCTCTTCGAATGGCTGGAAGGC
CAGTGCTACGCGGATCATCCGGAAGTGCACGAAGCTCTGGTTACGGAAACGCGCCACTTCGGCGTTTTGCTGGAAATCCC
GCGTCTCCAGATTAAGGGGCTGGTCAAACCGGACAAGCTTCCCGGCGGCCGCTGGGTGTATGAGGCGTTTGCCAGCCGCT
GGAAAAACGACCACGGTTCCGTGCTGTGCGCAGGGCTGCGCGTTCCCGTCATTCCCGTGAAAGTGGACAGGGAGCAGCAG
TGGGCGGATTTCGCCATCGTCTCACGGGAGAAACCGCGGCAAACGGGAAAAACGGCCTTCCCCACCAAACAGGAGAAGGG
CATATCCGGCCGCGGGCGGCGGAACCGCTGA

Upstream 100 bases:

>100_bases
GAACGCGGCATGCACCGCCCGCGCCTTGAAGCGGCGCGAAAACCTTCTTATGATGGCATCCATGGGAATGGGAAACTCCT
TTTCCCGGAACTTCCGTAAA

Downstream 100 bases:

>100_bases
CGGCAATACGCCCGTATATGGAAACAATCCCATCCGGAAATCAAATCCGATTCTCCCTGCAACAGAATCAAATCTACATT
TTCCTACACAATTTTTCTTG

Product: VacB and RNase II family 3'-5' exoribonuclease

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 756; Mature: 756

Protein sequence:

>756_residues
MNNSLKDRLIRHMEDGHYEPQSKSELARALNVDSRQKLDFRALVDQMEEEGKLVRLQKGRYALKRERRNLVHGMIRILRS
GKILFLPRKGDPAAAALGWDTEAVPELELKPNHLGTALDGDRVAVRVERKAARGRRNIRRNRFSSPDADMKARVEEVTER
ARSRWLGVFRTGKNKPGRVLGDGVSSPSSIELAEKPAMEVLPGQLVSVEPITCGEEKKAPRGKIVEVLGYPDEPHVDMEA
VIRKYGLSVEFPASVLRELETLPQTPSPGELARREDWTDRTVITIDPASARDFDDAISITATPSGWTLAVHIADVSHFVK
PGGSLDGEALRRGNSTYLPDRVLPMLPHRLSDDLCSLRPDVVRLTKVCEMKFDKKGKMLRARFADAFIRSKARLTYQEAF
AMLKGNDKGEVPSTVREAWNLASILRRNRYAKGALDLDFPEVRAVMDKDGRVTGIITEEYDESHQLIEECMLAANEAVAL
ALKNGNRPTIYRVHEEPDSAKLFEFGQLCRLYGHPVHDIDQRQYLNELMKSIKGSPDEQLLKLALLKSLMRARYDTEPLG
HYGLATPNYCHFTSPIRRYADLVVHRSLNPLLANPPKGAKGAGSTGRLEEDAEHISETERISASAEKDANRMKLFEWLEG
QCYADHPEVHEALVTETRHFGVLLEIPRLQIKGLVKPDKLPGGRWVYEAFASRWKNDHGSVLCAGLRVPVIPVKVDREQQ
WADFAIVSREKPRQTGKTAFPTKQEKGISGRGRRNR

Sequences:

>Translated_756_residues
MNNSLKDRLIRHMEDGHYEPQSKSELARALNVDSRQKLDFRALVDQMEEEGKLVRLQKGRYALKRERRNLVHGMIRILRS
GKILFLPRKGDPAAAALGWDTEAVPELELKPNHLGTALDGDRVAVRVERKAARGRRNIRRNRFSSPDADMKARVEEVTER
ARSRWLGVFRTGKNKPGRVLGDGVSSPSSIELAEKPAMEVLPGQLVSVEPITCGEEKKAPRGKIVEVLGYPDEPHVDMEA
VIRKYGLSVEFPASVLRELETLPQTPSPGELARREDWTDRTVITIDPASARDFDDAISITATPSGWTLAVHIADVSHFVK
PGGSLDGEALRRGNSTYLPDRVLPMLPHRLSDDLCSLRPDVVRLTKVCEMKFDKKGKMLRARFADAFIRSKARLTYQEAF
AMLKGNDKGEVPSTVREAWNLASILRRNRYAKGALDLDFPEVRAVMDKDGRVTGIITEEYDESHQLIEECMLAANEAVAL
ALKNGNRPTIYRVHEEPDSAKLFEFGQLCRLYGHPVHDIDQRQYLNELMKSIKGSPDEQLLKLALLKSLMRARYDTEPLG
HYGLATPNYCHFTSPIRRYADLVVHRSLNPLLANPPKGAKGAGSTGRLEEDAEHISETERISASAEKDANRMKLFEWLEG
QCYADHPEVHEALVTETRHFGVLLEIPRLQIKGLVKPDKLPGGRWVYEAFASRWKNDHGSVLCAGLRVPVIPVKVDREQQ
WADFAIVSREKPRQTGKTAFPTKQEKGISGRGRRNR
>Mature_756_residues
MNNSLKDRLIRHMEDGHYEPQSKSELARALNVDSRQKLDFRALVDQMEEEGKLVRLQKGRYALKRERRNLVHGMIRILRS
GKILFLPRKGDPAAAALGWDTEAVPELELKPNHLGTALDGDRVAVRVERKAARGRRNIRRNRFSSPDADMKARVEEVTER
ARSRWLGVFRTGKNKPGRVLGDGVSSPSSIELAEKPAMEVLPGQLVSVEPITCGEEKKAPRGKIVEVLGYPDEPHVDMEA
VIRKYGLSVEFPASVLRELETLPQTPSPGELARREDWTDRTVITIDPASARDFDDAISITATPSGWTLAVHIADVSHFVK
PGGSLDGEALRRGNSTYLPDRVLPMLPHRLSDDLCSLRPDVVRLTKVCEMKFDKKGKMLRARFADAFIRSKARLTYQEAF
AMLKGNDKGEVPSTVREAWNLASILRRNRYAKGALDLDFPEVRAVMDKDGRVTGIITEEYDESHQLIEECMLAANEAVAL
ALKNGNRPTIYRVHEEPDSAKLFEFGQLCRLYGHPVHDIDQRQYLNELMKSIKGSPDEQLLKLALLKSLMRARYDTEPLG
HYGLATPNYCHFTSPIRRYADLVVHRSLNPLLANPPKGAKGAGSTGRLEEDAEHISETERISASAEKDANRMKLFEWLEG
QCYADHPEVHEALVTETRHFGVLLEIPRLQIKGLVKPDKLPGGRWVYEAFASRWKNDHGSVLCAGLRVPVIPVKVDREQQ
WADFAIVSREKPRQTGKTAFPTKQEKGISGRGRRNR

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=513, Percent_Identity=30.0194931773879, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI190014625, Length=513, Percent_Identity=30.0194931773879, Blast_Score=198, Evalue=2e-50,
Organism=Homo sapiens, GI134288890, Length=400, Percent_Identity=34, Blast_Score=189, Evalue=7e-48,
Organism=Homo sapiens, GI19115966, Length=504, Percent_Identity=30.1587301587302, Blast_Score=165, Evalue=1e-40,
Organism=Homo sapiens, GI219521928, Length=504, Percent_Identity=30.1587301587302, Blast_Score=165, Evalue=2e-40,
Organism=Homo sapiens, GI156105695, Length=422, Percent_Identity=27.7251184834123, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI156105693, Length=421, Percent_Identity=28.2660332541568, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI87082383, Length=736, Percent_Identity=30.4347826086957, Blast_Score=294, Evalue=1e-80,
Organism=Escherichia coli, GI1787542, Length=459, Percent_Identity=29.8474945533769, Blast_Score=148, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17553506, Length=410, Percent_Identity=31.7073170731707, Blast_Score=178, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI212645896, Length=511, Percent_Identity=27.2015655577299, Blast_Score=165, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6324552, Length=494, Percent_Identity=28.3400809716599, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6320499, Length=497, Percent_Identity=23.1388329979879, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24649634, Length=402, Percent_Identity=31.3432835820896, Blast_Score=186, Evalue=5e-47,
Organism=Drosophila melanogaster, GI19922976, Length=378, Percent_Identity=31.2169312169312, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24654597, Length=378, Percent_Identity=31.2169312169312, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24654592, Length=378, Percent_Identity=31.2169312169312, Blast_Score=140, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 85158; Mature: 85158

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSLKDRLIRHMEDGHYEPQSKSELARALNVDSRQKLDFRALVDQMEEEGKLVRLQKGR
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCH
YALKRERRNLVHGMIRILRSGKILFLPRKGDPAAAALGWDTEAVPELELKPNHLGTALDG
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
DRVAVRVERKAARGRRNIRRNRFSSPDADMKARVEEVTERARSRWLGVFRTGKNKPGRVL
CEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
GDGVSSPSSIELAEKPAMEVLPGQLVSVEPITCGEEKKAPRGKIVEVLGYPDEPHVDMEA
CCCCCCCCCCCHHHCCCHHHCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCHHH
VIRKYGLSVEFPASVLRELETLPQTPSPGELARREDWTDRTVITIDPASARDFDDAISIT
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCEEEE
ATPSGWTLAVHIADVSHFVKPGGSLDGEALRRGNSTYLPDRVLPMLPHRLSDDLCSLRPD
ECCCCCEEEEEEEHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHCCHH
VVRLTKVCEMKFDKKGKMLRARFADAFIRSKARLTYQEAFAMLKGNDKGEVPSTVREAWN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LASILRRNRYAKGALDLDFPEVRAVMDKDGRVTGIITEEYDESHQLIEECMLAANEAVAL
HHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEE
ALKNGNRPTIYRVHEEPDSAKLFEFGQLCRLYGHPVHDIDQRQYLNELMKSIKGSPDEQL
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHH
LKLALLKSLMRARYDTEPLGHYGLATPNYCHFTSPIRRYADLVVHRSLNPLLANPPKGAK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
GAGSTGRLEEDAEHISETERISASAEKDANRMKLFEWLEGQCYADHPEVHEALVTETRHF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHC
GVLLEIPRLQIKGLVKPDKLPGGRWVYEAFASRWKNDHGSVLCAGLRVPVIPVKVDREQQ
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCHH
WADFAIVSREKPRQTGKTAFPTKQEKGISGRGRRNR
HHHHHEECCCCCHHCCCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MNNSLKDRLIRHMEDGHYEPQSKSELARALNVDSRQKLDFRALVDQMEEEGKLVRLQKGR
CCCCHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCH
YALKRERRNLVHGMIRILRSGKILFLPRKGDPAAAALGWDTEAVPELELKPNHLGTALDG
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCC
DRVAVRVERKAARGRRNIRRNRFSSPDADMKARVEEVTERARSRWLGVFRTGKNKPGRVL
CEEEEEEHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
GDGVSSPSSIELAEKPAMEVLPGQLVSVEPITCGEEKKAPRGKIVEVLGYPDEPHVDMEA
CCCCCCCCCCCHHHCCCHHHCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCHHH
VIRKYGLSVEFPASVLRELETLPQTPSPGELARREDWTDRTVITIDPASARDFDDAISIT
HHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCEEEE
ATPSGWTLAVHIADVSHFVKPGGSLDGEALRRGNSTYLPDRVLPMLPHRLSDDLCSLRPD
ECCCCCEEEEEEEHHHHHHCCCCCCCHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHCCHH
VVRLTKVCEMKFDKKGKMLRARFADAFIRSKARLTYQEAFAMLKGNDKGEVPSTVREAWN
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LASILRRNRYAKGALDLDFPEVRAVMDKDGRVTGIITEEYDESHQLIEECMLAANEAVAL
HHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHCCCEEEE
ALKNGNRPTIYRVHEEPDSAKLFEFGQLCRLYGHPVHDIDQRQYLNELMKSIKGSPDEQL
EEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHH
LKLALLKSLMRARYDTEPLGHYGLATPNYCHFTSPIRRYADLVVHRSLNPLLANPPKGAK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCC
GAGSTGRLEEDAEHISETERISASAEKDANRMKLFEWLEGQCYADHPEVHEALVTETRHF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHC
GVLLEIPRLQIKGLVKPDKLPGGRWVYEAFASRWKNDHGSVLCAGLRVPVIPVKVDREQQ
EEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCCCEEEEEECCCHH
WADFAIVSREKPRQTGKTAFPTKQEKGISGRGRRNR
HHHHHEECCCCCHHCCCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]