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The map label for this gene is 187735321

Identifier: 187735321

GI number: 187735321

Start: 964236

End: 965615

Strand: Reverse

Name: 187735321

Synonym: Amuc_0819

Alternate gene names: NA

Gene position: 965615-964236 (Counterclockwise)

Preceding gene: 187735322

Following gene: 187735320

Centisome position: 36.25

GC content: 47.03

Gene sequence:

>1380_bases
ATGAAAAGAAATGCAATTGATTTAGGCACACTGGACGTATGCACATTATTCAGAAAGTATTTTATCCCGACCTTATTCGG
GATGCTTAGCATATCGGCAGTAACGGCAGTAGACGGAATACTCGTCGGTCACGGAATCGGAAGCGATGGCATTGCCGCTA
TCAATATATGCATTCCCCTGCTGATGTTGTTTACCGGGATAGGGCTCATGGCAGGCGTAGGCTCATCCGTAGTCGCTTCC
ATTCAGCTATCAAAAGGAAAACTGGAAGCCGCGCGCCTTAATGTCACCCAGGCCTTGTTGTTCGTCACCATTGCCGCCAT
CGTGCCATCTGCCTTGATGATGGCATATCCGTCAGCTACAGCCCGATTTTTAGGCGCTTCCGAACATCTTACCCCCATGG
TTAGGGAATACCTGTTGTGGTTCATCCCCTCGTTGATATTCCAGATGTGGTGCTCTGTCTGCCTATTCATGATTCGTTTG
GATGGCGCTCCGAAGTTGGCTATGATGTGCAATATCATTGCTGCAATCATCACCGTAATACTCGGTTGGCTGTTTATCTT
TCCATTGGGCTGGGGATTGACGGGAGCTGCTTTCGCCGCAACCATAGCACTGTTTGCGAGCGGCGCCACGGGCCTTATTT
ATTTATGGATATTTGCACATAAACTGCGGCTTTATCCTATTAAATGGAGCATCAGAAGTTTTCGGTTCTCCCTCCTTAAT
ATTGTCTGCCAATGTCGCATCGGTTCTTCCGCTTTGCTGACTGAAGCGACACTGGCCACGCTCATGTTCGTCGGGAACCA
CACATTGATGAAATATCTGGGAGATAATGGAGTAGGAGCGTTCGGCATTGCCTGCTATTACCTTCCGTTCGTATTCATGG
TAGGCAATGCCATAGCGCAATCAGCGCAACCCATCATCAGCTATAACTTCGGGCTTGGAGAGAAAAAACGCGTAGCCGAT
ACAAAACGGATCGCATTATTTACCTCCGTTGTTTGCGGCATAGTCACGACGGCAGCATTCATTTTGTTCCCGCATATTCT
GGTAGGCTTGTTCGTCAATCCGGACAGCACTGCGGCGCTCATAGCCATTGAGGGATTTCCATATTTCTCCCTGGCATTTG
TTTTCTTCATCATCAACCTGATGCTCATCGGTTATTACCAAAGCGTGGAAAATGTAAAACTCGCCAATTTGTTTGCCCTG
TTGCGAGGATTTGTTTTTCTTATTCCATGCTTTATCCTGTTGCCTGAAGCAATGGGAACGAACGGTGCGTGGCTAGCACT
TTGTCTGTCGGAAATGTTGACCATATTAACAGTTGCTGTCCTATTTATTCTACGCAAAAAGAAAACACTTCTTCATCAAA
CAGGTGAAGAATGCAGTTAA

Upstream 100 bases:

>100_bases
CAAATAAAAATGCCGGATAAGATGACTGGGTAAAACCAATCACCTTATCCGGCATTTTTTGTTTCCCGGCAAAAAATAGC
CATAAGAATAACAGACACAT

Downstream 100 bases:

>100_bases
AAAGATTGTTCTCAGGCATGCCACGACACACGCATAAAATACTTGCAAGCGAATATAGATGACTTAGCACTTTGTCTTCC
CTGAACTGGCTACAGCTTTT

Product: multi antimicrobial extrusion protein MatE

Products: NA

Alternate protein names: Multi Antimicrobial Extrusion Protein MatE; Na+ Driven Multidrug Efflux Pump; Multidrug Efflux Pump VmrA; Mate Efflux Family Protein; Multi Anti Extrusion Protein MatE; Na+-Driven Multidrug Efflux Pump; Drug/Sodium Antiporter; Cation Transport Related Membrane Protein; MOP/MATE Family Multidrug-Resistance Efflux Pump; Transmembrane Efflux Protein; Cation Efflux Pump; Na+Driven Multidrug Efflux Pump; Transmembrane Cation Efflux Protein; Na+ Driven Multidrug Efflux Protein; LOW QUALITY PROTEIN Na+ Driven Multidrug Efflux Pump; DNA Damage-Inducible Protein; Efflux Protein MATE Family; Cation Multidrug Resistance Efflux Pump; MatE Family; MATE Efflux Family Protein Subfamily; DinF Protein; MATE Efflux Family Protein Authentic Frameshift; Drug/Sodium Antiporters; MOP/MATE Family Multidrug-Resistance Efflux PumpNorM; Multidrug Resistance Protein; Na+-Driven Multidrug Efflux Pump NorM; MatE Family Transport-Related Membrane Protein; MATE Family Efflux Protein; MatE Efflux Family Protein; Na+-Driven MATE Multi-Drug Efflux Protein; Membrane Pump; Multidrug Resistance Efflux Pump

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MKRNAIDLGTLDVCTLFRKYFIPTLFGMLSISAVTAVDGILVGHGIGSDGIAAINICIPLLMLFTGIGLMAGVGSSVVAS
IQLSKGKLEAARLNVTQALLFVTIAAIVPSALMMAYPSATARFLGASEHLTPMVREYLLWFIPSLIFQMWCSVCLFMIRL
DGAPKLAMMCNIIAAIITVILGWLFIFPLGWGLTGAAFAATIALFASGATGLIYLWIFAHKLRLYPIKWSIRSFRFSLLN
IVCQCRIGSSALLTEATLATLMFVGNHTLMKYLGDNGVGAFGIACYYLPFVFMVGNAIAQSAQPIISYNFGLGEKKRVAD
TKRIALFTSVVCGIVTTAAFILFPHILVGLFVNPDSTAALIAIEGFPYFSLAFVFFIINLMLIGYYQSVENVKLANLFAL
LRGFVFLIPCFILLPEAMGTNGAWLALCLSEMLTILTVAVLFILRKKKTLLHQTGEECS

Sequences:

>Translated_459_residues
MKRNAIDLGTLDVCTLFRKYFIPTLFGMLSISAVTAVDGILVGHGIGSDGIAAINICIPLLMLFTGIGLMAGVGSSVVAS
IQLSKGKLEAARLNVTQALLFVTIAAIVPSALMMAYPSATARFLGASEHLTPMVREYLLWFIPSLIFQMWCSVCLFMIRL
DGAPKLAMMCNIIAAIITVILGWLFIFPLGWGLTGAAFAATIALFASGATGLIYLWIFAHKLRLYPIKWSIRSFRFSLLN
IVCQCRIGSSALLTEATLATLMFVGNHTLMKYLGDNGVGAFGIACYYLPFVFMVGNAIAQSAQPIISYNFGLGEKKRVAD
TKRIALFTSVVCGIVTTAAFILFPHILVGLFVNPDSTAALIAIEGFPYFSLAFVFFIINLMLIGYYQSVENVKLANLFAL
LRGFVFLIPCFILLPEAMGTNGAWLALCLSEMLTILTVAVLFILRKKKTLLHQTGEECS
>Mature_459_residues
MKRNAIDLGTLDVCTLFRKYFIPTLFGMLSISAVTAVDGILVGHGIGSDGIAAINICIPLLMLFTGIGLMAGVGSSVVAS
IQLSKGKLEAARLNVTQALLFVTIAAIVPSALMMAYPSATARFLGASEHLTPMVREYLLWFIPSLIFQMWCSVCLFMIRL
DGAPKLAMMCNIIAAIITVILGWLFIFPLGWGLTGAAFAATIALFASGATGLIYLWIFAHKLRLYPIKWSIRSFRFSLLN
IVCQCRIGSSALLTEATLATLMFVGNHTLMKYLGDNGVGAFGIACYYLPFVFMVGNAIAQSAQPIISYNFGLGEKKRVAD
TKRIALFTSVVCGIVTTAAFILFPHILVGLFVNPDSTAALIAIEGFPYFSLAFVFFIINLMLIGYYQSVENVKLANLFAL
LRGFVFLIPCFILLPEAMGTNGAWLALCLSEMLTILTVAVLFILRKKKTLLHQTGEECS

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 49840; Mature: 49840

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA