| Definition | Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)' chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_010602 |
| Length | 3,599,677 |
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The map label for this gene is clpB [H]
Identifier: 183221818
GI number: 183221818
Start: 2524272
End: 2526659
Strand: Reverse
Name: clpB [H]
Synonym: LEPBI_I2449
Alternate gene names: 183221818
Gene position: 2526659-2524272 (Counterclockwise)
Preceding gene: 183221820
Following gene: 183221817
Centisome position: 70.19
GC content: 38.69
Gene sequence:
>2388_bases ATGAAACAATATGACTCTAACGTCCAAGGAGCCTTGGACATAGCGCAAACAGAGGCGATCAGGAGACAAAATACAGAAAT CACTCCTTATCATTTGGTGTGGGGGTTTATGACCTTACCAACTTCTGTTTCAGGAAAATCATTGATTCGATATAAATCTA CAGTTGATGAATATTTAAAGAAACAAGCAAGGGCTTCCGGGGAAATCCCTTTCGATTCCCTACGAACTTCACCAAAACTT GCCCAGTGGTTTACCATGGCGTCCTCAAGAGCCGCAGAGAATGGTAGAGAGGAATTGAAAGAGGCCGATTTTTTAAAATT TTTACCTCAAATCCTTCCTGAGCTAAAAATCAATTATGAAGATCTCAACGTAAAAGAGACAGACGAAGAAGTTCCCAATT TTCTAGTGAATTTGAATGATTTGGCTCGAGAAGGTAAATTGGATCCGGTCATTGGTCGAAGTAAAGAGATTCGTTCCGTC ATGGAAATTTTAGGGAGAAGGTCAAAAAACAATCCTGTGTTAGTGGGTAGTGCAGGAGTTGGTAAAACTGCGATTGTGGA AGGTCTTGCCGAGCAGATTGTAAAAGGAAGAGTACCTGATGTTCTGAAAGGTAAAACCATTTTTTCTCTAGATATGGGAC AATTGATGGCGGGAACCAAATATCGTGGAGAATTTGAGGAAAAACTAACGGCACTTTTGCGATATATAAAGGGACAAGCA GGTGAAGCGATTTTGTTTATCGATGAAATCCATCAATTGGTTGGTGCTGGAAAAACCGATGGAGCAATGGATGCTGCCAA TTTATTAAAACCTGCACTTGCTCGAGGTGAATTGCATTGTATTGGTGCAACAACTGGTGATGAATTCCAGAAATACATTC TAGGAGACCAAGCATTAGAAAGAAGATTTCGTGCAGTTCCTGTCAATGAACCGAGCAAAGAAGATGCGATTGAAATCCTT ATGGGAATACGAGATAAACATGAAATCCATCATGGAATTAAAATTTCCGATGAAGCAATTTATGCATCGGTACTTTTATC AGACCAATACATTACTGATAAATTTTTGCCAGATAAAGCAATTGACTTGGTAGATGAAGCTGCATCTGCCTTGAAGTTAT CTGCAGAAGCAATGCCTACGGAGCTCGTGGAATTGGAAGGCGAAATTCGTTCTAAAAAAATCTTTGCTCAAGTTGAAAAG AAAAACGAAGAGATTTTAAAAGAGATCGAAGTCTTAGAAAAAAAATTCCAAGCAGGCAAAGAGATTTGGGAAAAAGAAGT TAATTCTTTGAAACAAATCGCATCGATTAAAAATAAAATTGATCGAGTCAAATTTGATTTGGATGCGGCACAACAAAGAG CCGATTACACTGAAGCTTCGCGATTGAAGTATGCAGTTTTGCCAGAATTGGAGAAAGAACTTAGCACATTTCAAAACAGT TGGATTCTCGAAAGAAACCACATTGCTGCTGTTATAGCAAGACAAACTGGTATTCCTGTGGAGAAGATACTAAAAACCAA ACAAGAAAACTTACTTCACTTAGAAGACGATTTGAACTCTGTTGTGTATGGTCAAAAAGAATCCATAAGAGAGATTGCAG ATACGCTTTTAACATCGTATGCTGGCATTTCATCTGAAACAAGACCACTCGGATCATTTTTGCTAAAAGGGCCCACAGGT GTTGGTAAAACGGAAACTGCAAAAGCGATTGCTAAGTTTTTGTTCGATCAAGAATCTAATTTAGTCCGTTTGGACTTAAG TGAGTATTCCGAAAAACATTCTGTTGCAAAACTCATCGGTGCTCCTGCAGGATACATAGGTTATGATGAAGGTGGAATTT TGACTGAGGCCATTCGTCGTAAACCATATTCGGTCGTTTTATTTGACGAGGTAGAAAAAGCTCACCCGGACTTTTCCGAT ATTCTACTGCAAATATTAGATGATGGAAGATTGACAGATAACAAAGGTAGAACGATCAATTTTAAAAATACCATTGTTAT CCTTACGACAAATTCAAAAAATATTGAAGTCGATTTTAAACCAGAGGTATTAGGTAGATTAGATGCCATTTTGACCTATC ATTCATTAGATTCTTCGATCATGGAGAAACTAATCGAAAAACAACTTCGATCGTTGAATGATCGATTGAAGGTAAAGGGT GTAGTCATCGAACTGTCCGAGAGTACTGAACATATTTTGCGTGAACAAGGGTTTGATCCAAAATTTGGAGCGCGACCTCT CGGAAGTGTTTTCAACCGCATTGTCAATCGACCATTAGCTAAGGCGATCCTTTCTGGAACTATGGTCGAAGGGAAATATA GAGCGGATTGGGATGGAGAAAATCTTCAATTTGCGTTACTCCAGGAAGCTACTGGCGTAAAAAAATAA
Upstream 100 bases:
>100_bases ACGAAGTTTGCTTCCCTGAAAGCCCTTTTCAAAAAAAACTTGTAACAAGAACTCAAAATTAGCAGTCTAATGGTTAGAGT GCTAAAAGTGAGGAAACACT
Downstream 100 bases:
>100_bases GTTCATAGAAACCATTGAAACCCTACTGTAAATCAGTTTATGGTAGGGTTTTTTCGTCTAAAGAAGTAATTATGTCTGAA CTCAATCTTACCTCCACAAT
Product: chaperone ClpB
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 795; Mature: 795
Protein sequence:
>795_residues MKQYDSNVQGALDIAQTEAIRRQNTEITPYHLVWGFMTLPTSVSGKSLIRYKSTVDEYLKKQARASGEIPFDSLRTSPKL AQWFTMASSRAAENGREELKEADFLKFLPQILPELKINYEDLNVKETDEEVPNFLVNLNDLAREGKLDPVIGRSKEIRSV MEILGRRSKNNPVLVGSAGVGKTAIVEGLAEQIVKGRVPDVLKGKTIFSLDMGQLMAGTKYRGEFEEKLTALLRYIKGQA GEAILFIDEIHQLVGAGKTDGAMDAANLLKPALARGELHCIGATTGDEFQKYILGDQALERRFRAVPVNEPSKEDAIEIL MGIRDKHEIHHGIKISDEAIYASVLLSDQYITDKFLPDKAIDLVDEAASALKLSAEAMPTELVELEGEIRSKKIFAQVEK KNEEILKEIEVLEKKFQAGKEIWEKEVNSLKQIASIKNKIDRVKFDLDAAQQRADYTEASRLKYAVLPELEKELSTFQNS WILERNHIAAVIARQTGIPVEKILKTKQENLLHLEDDLNSVVYGQKESIREIADTLLTSYAGISSETRPLGSFLLKGPTG VGKTETAKAIAKFLFDQESNLVRLDLSEYSEKHSVAKLIGAPAGYIGYDEGGILTEAIRRKPYSVVLFDEVEKAHPDFSD ILLQILDDGRLTDNKGRTINFKNTIVILTTNSKNIEVDFKPEVLGRLDAILTYHSLDSSIMEKLIEKQLRSLNDRLKVKG VVIELSESTEHILREQGFDPKFGARPLGSVFNRIVNRPLAKAILSGTMVEGKYRADWDGENLQFALLQEATGVKK
Sequences:
>Translated_795_residues MKQYDSNVQGALDIAQTEAIRRQNTEITPYHLVWGFMTLPTSVSGKSLIRYKSTVDEYLKKQARASGEIPFDSLRTSPKL AQWFTMASSRAAENGREELKEADFLKFLPQILPELKINYEDLNVKETDEEVPNFLVNLNDLAREGKLDPVIGRSKEIRSV MEILGRRSKNNPVLVGSAGVGKTAIVEGLAEQIVKGRVPDVLKGKTIFSLDMGQLMAGTKYRGEFEEKLTALLRYIKGQA GEAILFIDEIHQLVGAGKTDGAMDAANLLKPALARGELHCIGATTGDEFQKYILGDQALERRFRAVPVNEPSKEDAIEIL MGIRDKHEIHHGIKISDEAIYASVLLSDQYITDKFLPDKAIDLVDEAASALKLSAEAMPTELVELEGEIRSKKIFAQVEK KNEEILKEIEVLEKKFQAGKEIWEKEVNSLKQIASIKNKIDRVKFDLDAAQQRADYTEASRLKYAVLPELEKELSTFQNS WILERNHIAAVIARQTGIPVEKILKTKQENLLHLEDDLNSVVYGQKESIREIADTLLTSYAGISSETRPLGSFLLKGPTG VGKTETAKAIAKFLFDQESNLVRLDLSEYSEKHSVAKLIGAPAGYIGYDEGGILTEAIRRKPYSVVLFDEVEKAHPDFSD ILLQILDDGRLTDNKGRTINFKNTIVILTTNSKNIEVDFKPEVLGRLDAILTYHSLDSSIMEKLIEKQLRSLNDRLKVKG VVIELSESTEHILREQGFDPKFGARPLGSVFNRIVNRPLAKAILSGTMVEGKYRADWDGENLQFALLQEATGVKK >Mature_795_residues MKQYDSNVQGALDIAQTEAIRRQNTEITPYHLVWGFMTLPTSVSGKSLIRYKSTVDEYLKKQARASGEIPFDSLRTSPKL AQWFTMASSRAAENGREELKEADFLKFLPQILPELKINYEDLNVKETDEEVPNFLVNLNDLAREGKLDPVIGRSKEIRSV MEILGRRSKNNPVLVGSAGVGKTAIVEGLAEQIVKGRVPDVLKGKTIFSLDMGQLMAGTKYRGEFEEKLTALLRYIKGQA GEAILFIDEIHQLVGAGKTDGAMDAANLLKPALARGELHCIGATTGDEFQKYILGDQALERRFRAVPVNEPSKEDAIEIL MGIRDKHEIHHGIKISDEAIYASVLLSDQYITDKFLPDKAIDLVDEAASALKLSAEAMPTELVELEGEIRSKKIFAQVEK KNEEILKEIEVLEKKFQAGKEIWEKEVNSLKQIASIKNKIDRVKFDLDAAQQRADYTEASRLKYAVLPELEKELSTFQNS WILERNHIAAVIARQTGIPVEKILKTKQENLLHLEDDLNSVVYGQKESIREIADTLLTSYAGISSETRPLGSFLLKGPTG VGKTETAKAIAKFLFDQESNLVRLDLSEYSEKHSVAKLIGAPAGYIGYDEGGILTEAIRRKPYSVVLFDEVEKAHPDFSD ILLQILDDGRLTDNKGRTINFKNTIVILTTNSKNIEVDFKPEVLGRLDAILTYHSLDSSIMEKLIEKQLRSLNDRLKVKG VVIELSESTEHILREQGFDPKFGARPLGSVFNRIVNRPLAKAILSGTMVEGKYRADWDGENLQFALLQEATGVKK
Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase
COG id: COG0542
COG function: function code O; ATPases with chaperone activity, ATP-binding subunit
Gene ontology:
Cell location: Cytoplasm (Probable) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the clpA/clpB family [H]
Homologues:
Organism=Homo sapiens, GI13540606, Length=245, Percent_Identity=37.9591836734694, Blast_Score=154, Evalue=2e-37, Organism=Escherichia coli, GI1788943, Length=692, Percent_Identity=46.242774566474, Blast_Score=638, Evalue=0.0, Organism=Escherichia coli, GI1787109, Length=247, Percent_Identity=50.6072874493927, Blast_Score=258, Evalue=7e-70, Organism=Saccharomyces cerevisiae, GI6320464, Length=709, Percent_Identity=43.3004231311707, Blast_Score=594, Evalue=1e-170, Organism=Saccharomyces cerevisiae, GI6323002, Length=687, Percent_Identity=37.5545851528384, Blast_Score=473, Evalue=1e-134,
Paralogues:
None
Copy number: 560 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003593 - InterPro: IPR013093 - InterPro: IPR003959 - InterPro: IPR018368 - InterPro: IPR017730 - InterPro: IPR001270 - InterPro: IPR019489 - InterPro: IPR004176 - InterPro: IPR023150 [H]
Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]
EC number: NA
Molecular weight: Translated: 88853; Mature: 88853
Theoretical pI: Translated: 5.70; Mature: 5.70
Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.1 %Cys (Translated Protein) 1.4 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.1 %Cys (Mature Protein) 1.4 %Met (Mature Protein) 1.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKQYDSNVQGALDIAQTEAIRRQNTEITPYHLVWGFMTLPTSVSGKSLIRYKSTVDEYLK CCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH KQARASGEIPFDSLRTSPKLAQWFTMASSRAAENGREELKEADFLKFLPQILPELKINYE HHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC DLNVKETDEEVPNFLVNLNDLAREGKLDPVIGRSKEIRSVMEILGRRSKNNPVLVGSAGV CCCCCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCC GKTAIVEGLAEQIVKGRVPDVLKGKTIFSLDMGQLMAGTKYRGEFEEKLTALLRYIKGQA CHHHHHHHHHHHHHHCCCCCHHCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHCCCC GEAILFIDEIHQLVGAGKTDGAMDAANLLKPALARGELHCIGATTGDEFQKYILGDQALE CCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCHHHHH RRFRAVPVNEPSKEDAIEILMGIRDKHEIHHGIKISDEAIYASVLLSDQYITDKFLPDKA HHHHCCCCCCCCHHHHHHHHHHCCHHHHHHCCCEECCHHHHHHHHHCCCHHHHHCCCHHH IDLVDEAASALKLSAEAMPTELVELEGEIRSKKIFAQVEKKNEEILKEIEVLEKKFQAGK HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH EIWEKEVNSLKQIASIKNKIDRVKFDLDAAQQRADYTEASRLKYAVLPELEKELSTFQNS HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHCEEHHHHHHHHHHHHHHHC WILERNHIAAVIARQTGIPVEKILKTKQENLLHLEDDLNSVVYGQKESIREIADTLLTSY CEEECCHHEEEEEHHCCCCHHHHHHHHHHCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHH AGISSETRPLGSFLLKGPTGVGKTETAKAIAKFLFDQESNLVRLDLSEYSEKHSVAKLIG CCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHC APAGYIGYDEGGILTEAIRRKPYSVVLFDEVEKAHPDFSDILLQILDDGRLTDNKGRTIN CCCCCCCCCCCCHHHHHHHCCCCEEEEEECHHHHCCCHHHHHHHHHCCCCEECCCCCEEE FKNTIVILTTNSKNIEVDFKPEVLGRLDAILTYHSLDSSIMEKLIEKQLRSLNDRLKVKG ECCEEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE VVIELSESTEHILREQGFDPKFGARPLGSVFNRIVNRPLAKAILSGTMVEGKYRADWDGE EEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCEECCCEECCCCCC NLQFALLQEATGVKK CCEEEEEHHHCCCCC >Mature Secondary Structure MKQYDSNVQGALDIAQTEAIRRQNTEITPYHLVWGFMTLPTSVSGKSLIRYKSTVDEYLK CCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH KQARASGEIPFDSLRTSPKLAQWFTMASSRAAENGREELKEADFLKFLPQILPELKINYE HHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC DLNVKETDEEVPNFLVNLNDLAREGKLDPVIGRSKEIRSVMEILGRRSKNNPVLVGSAGV CCCCCCCHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCCC GKTAIVEGLAEQIVKGRVPDVLKGKTIFSLDMGQLMAGTKYRGEFEEKLTALLRYIKGQA CHHHHHHHHHHHHHHCCCCCHHCCCEEEEECHHHHHCCCCCCCHHHHHHHHHHHHHCCCC GEAILFIDEIHQLVGAGKTDGAMDAANLLKPALARGELHCIGATTGDEFQKYILGDQALE CCEEEEHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCHHHHH RRFRAVPVNEPSKEDAIEILMGIRDKHEIHHGIKISDEAIYASVLLSDQYITDKFLPDKA HHHHCCCCCCCCHHHHHHHHHHCCHHHHHHCCCEECCHHHHHHHHHCCCHHHHHCCCHHH IDLVDEAASALKLSAEAMPTELVELEGEIRSKKIFAQVEKKNEEILKEIEVLEKKFQAGK HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH EIWEKEVNSLKQIASIKNKIDRVKFDLDAAQQRADYTEASRLKYAVLPELEKELSTFQNS HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHCEEHHHHHHHHHHHHHHHC WILERNHIAAVIARQTGIPVEKILKTKQENLLHLEDDLNSVVYGQKESIREIADTLLTSY CEEECCHHEEEEEHHCCCCHHHHHHHHHHCCEEHHHHHHHHHCCCHHHHHHHHHHHHHHH AGISSETRPLGSFLLKGPTGVGKTETAKAIAKFLFDQESNLVRLDLSEYSEKHSVAKLIG CCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHC APAGYIGYDEGGILTEAIRRKPYSVVLFDEVEKAHPDFSDILLQILDDGRLTDNKGRTIN CCCCCCCCCCCCHHHHHHHCCCCEEEEEECHHHHCCCHHHHHHHHHCCCCEECCCCCEEE FKNTIVILTTNSKNIEVDFKPEVLGRLDAILTYHSLDSSIMEKLIEKQLRSLNDRLKVKG ECCEEEEEEECCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEE VVIELSESTEHILREQGFDPKFGARPLGSVFNRIVNRPLAKAILSGTMVEGKYRADWDGE EEEEECCHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCEECCCEECCCCCC NLQFALLQEATGVKK CCEEEEEHHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12024217 [H]