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The map label for this gene is kamA [H]

Identifier: 183221183

GI number: 183221183

Start: 1874403

End: 1875611

Strand: Reverse

Name: kamA [H]

Synonym: LEPBI_I1797

Alternate gene names: 183221183

Gene position: 1875611-1874403 (Counterclockwise)

Preceding gene: 183221187

Following gene: 183221182

Centisome position: 52.1

GC content: 40.78

Gene sequence:

>1209_bases
ATGCTCGTGCAAAACAGTTTATCAGAAGTTCTTCGGGCCAGAGAAGAATTGTTTTCTAGGACAAATTGGAACGACCCCAC
CTCACAACTTCAAAACCGTGTGAAGGGAGAAGATCTCGCGCGTTATTTTGTCTTGTCTGATTCAGAACGTGTGGGGATCC
AAAACACAATCCGACTCCTTGTCTCGACAACCCCATATTATTTATCTTTGTCAGATCCAAGTGACCCGAATTGCCCGATT
CGTAGGATGATTGTTCCAACAAAGGAAGAAGCCATTTTTTCTTTGGAGGAAAGTGCAGATCCTTTGGAAGAAGAAAGGTT
AAGCCCTGTTCGTGGGCTCACTCATATGTATCCGAATCGAGTCCTTTTATTTTCGAATCACTCGTGCAGTGTGTATTGCC
GTCATTGTATGCGCGGAAGGAAGGTTTCATCGAATGAAGAAAGGATGGAAAAATCGGATTTGGAATCTGCCTTTGACTAT
ATCAGAAATCATCCTGAGATAGAAGATGTTGTCGTGAGTGGGGGTGATCCTTTGAACCTTGCGGATCTTCGGATTGAATG
GATTTTAAAAGAACTCAACCAAATCCCCCATGTAAAAATTTGCCGATTGGGAACACGAAATCCTGTCACACTTCCGTTTC
GCATAACAGATGCCATTTGTCAAATCATCGAAAAATACAATGATGACAATTTATCCATTTTTTGTAACACTCAATTCAAT
CATCCAAAAGAATGCACAAAGGAAACAAAAGAAGCGATCCTTAAGTTATTAAAGGTGGGAGTTTCTGTTGGGAACCAAGC
GGTTTTACTCAAAGGAATTAATGATGATGAAGAAACCATGTTAACACTTCATAAGAAGTTATTAGAAATGCGTGTGAGGG
CCTATTACTTATATGACCCAGAACTCATTCCTGGTTCTCGAGGTTTTCGTACACCTCTGGCACGTGGCATAGAAATCGTA
GAATACATGCGAGGGAAAATTGGTGGGATGGGGATTCCTCAGTTTGTGAACGATTTACCTGGTGGGGGTGGTAAAATCAC
AATTGGTGCCAACTGGTATTTAGGTTTCTATCCAAAAACGAGACAACATGTTTTCCGATCTGCTGTGACAAAAAAGATCC
ATTTCTCTTTTGAACCAATTGGTTCAAACAAGGAATCTTATTATCCAAAAATCTCAGATGAAGAATGGGAGAAATGGAAA
CCAAGATGA

Upstream 100 bases:

>100_bases
GACATCGAAGGCGACCATTCGGATTTCCCCCAAGCGGTTTTCTTGCATTACCACCAGAAAAGAATTTGGTGGTCTGTTGG
CAAGTAAGGAATAAAATCTT

Downstream 100 bases:

>100_bases
AAACTGTTCTCATCGCTTGTGATATCTACGACAAACAACATCCAAAACTTTCCCAAGAATGGGAATCGGAAGAAACCATC
CTTCACATGGAAAAAACGAT

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MLVQNSLSEVLRAREELFSRTNWNDPTSQLQNRVKGEDLARYFVLSDSERVGIQNTIRLLVSTTPYYLSLSDPSDPNCPI
RRMIVPTKEEAIFSLEESADPLEEERLSPVRGLTHMYPNRVLLFSNHSCSVYCRHCMRGRKVSSNEERMEKSDLESAFDY
IRNHPEIEDVVVSGGDPLNLADLRIEWILKELNQIPHVKICRLGTRNPVTLPFRITDAICQIIEKYNDDNLSIFCNTQFN
HPKECTKETKEAILKLLKVGVSVGNQAVLLKGINDDEETMLTLHKKLLEMRVRAYYLYDPELIPGSRGFRTPLARGIEIV
EYMRGKIGGMGIPQFVNDLPGGGGKITIGANWYLGFYPKTRQHVFRSAVTKKIHFSFEPIGSNKESYYPKISDEEWEKWK
PR

Sequences:

>Translated_402_residues
MLVQNSLSEVLRAREELFSRTNWNDPTSQLQNRVKGEDLARYFVLSDSERVGIQNTIRLLVSTTPYYLSLSDPSDPNCPI
RRMIVPTKEEAIFSLEESADPLEEERLSPVRGLTHMYPNRVLLFSNHSCSVYCRHCMRGRKVSSNEERMEKSDLESAFDY
IRNHPEIEDVVVSGGDPLNLADLRIEWILKELNQIPHVKICRLGTRNPVTLPFRITDAICQIIEKYNDDNLSIFCNTQFN
HPKECTKETKEAILKLLKVGVSVGNQAVLLKGINDDEETMLTLHKKLLEMRVRAYYLYDPELIPGSRGFRTPLARGIEIV
EYMRGKIGGMGIPQFVNDLPGGGGKITIGANWYLGFYPKTRQHVFRSAVTKKIHFSFEPIGSNKESYYPKISDEEWEKWK
PR
>Mature_402_residues
MLVQNSLSEVLRAREELFSRTNWNDPTSQLQNRVKGEDLARYFVLSDSERVGIQNTIRLLVSTTPYYLSLSDPSDPNCPI
RRMIVPTKEEAIFSLEESADPLEEERLSPVRGLTHMYPNRVLLFSNHSCSVYCRHCMRGRKVSSNEERMEKSDLESAFDY
IRNHPEIEDVVVSGGDPLNLADLRIEWILKELNQIPHVKICRLGTRNPVTLPFRITDAICQIIEKYNDDNLSIFCNTQFN
HPKECTKETKEAILKLLKVGVSVGNQAVLLKGINDDEETMLTLHKKLLEMRVRAYYLYDPELIPGSRGFRTPLARGIEIV
EYMRGKIGGMGIPQFVNDLPGGGGKITIGANWYLGFYPKTRQHVFRSAVTKKIHFSFEPIGSNKESYYPKISDEEWEKWK
PR

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=330, Percent_Identity=30.6060606060606, Blast_Score=171, Evalue=6e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 46201; Mature: 46201

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVQNSLSEVLRAREELFSRTNWNDPTSQLQNRVKGEDLARYFVLSDSERVGIQNTIRLL
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHEEEEECCCCCCCHHHHHHHH
VSTTPYYLSLSDPSDPNCPIRRMIVPTKEEAIFSLEESADPLEEERLSPVRGLTHMYPNR
EECCCEEEEECCCCCCCCCEEEEECCCCHHHHEECHHCCCCHHHHHCCHHHHHHHHCCCE
VLLFSNHSCSVYCRHCMRGRKVSSNEERMEKSDLESAFDYIRNHPEIEDVVVSGGDPLNL
EEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCH
ADLRIEWILKELNQIPHVKICRLGTRNPVTLPFRITDAICQIIEKYNDDNLSIFCNTQFN
HHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEEECCCC
HPKECTKETKEAILKLLKVGVSVGNQAVLLKGINDDEETMLTLHKKLLEMRVRAYYLYDP
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEECC
ELIPGSRGFRTPLARGIEIVEYMRGKIGGMGIPQFVNDLPGGGGKITIGANWYLGFYPKT
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEECEEEEECCCHH
RQHVFRSAVTKKIHFSFEPIGSNKESYYPKISDEEWEKWKPR
HHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCHHHHCCCC
>Mature Secondary Structure
MLVQNSLSEVLRAREELFSRTNWNDPTSQLQNRVKGEDLARYFVLSDSERVGIQNTIRLL
CCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHEEEEECCCCCCCHHHHHHHH
VSTTPYYLSLSDPSDPNCPIRRMIVPTKEEAIFSLEESADPLEEERLSPVRGLTHMYPNR
EECCCEEEEECCCCCCCCCEEEEECCCCHHHHEECHHCCCCHHHHHCCHHHHHHHHCCCE
VLLFSNHSCSVYCRHCMRGRKVSSNEERMEKSDLESAFDYIRNHPEIEDVVVSGGDPLNL
EEEEECCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHEEEECCCCCCCH
ADLRIEWILKELNQIPHVKICRLGTRNPVTLPFRITDAICQIIEKYNDDNLSIFCNTQFN
HHHHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEHHHHHHHHHHHCCCCCEEEEEECCCC
HPKECTKETKEAILKLLKVGVSVGNQAVLLKGINDDEETMLTLHKKLLEMRVRAYYLYDP
CHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEEEEECC
ELIPGSRGFRTPLARGIEIVEYMRGKIGGMGIPQFVNDLPGGGGKITIGANWYLGFYPKT
CCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCEEEEECEEEEECCCHH
RQHVFRSAVTKKIHFSFEPIGSNKESYYPKISDEEWEKWKPR
HHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]