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The map label for this gene is fnr [H]

Identifier: 183220276

GI number: 183220276

Start: 890562

End: 891260

Strand: Direct

Name: fnr [H]

Synonym: LEPBI_I0871

Alternate gene names: 183220276

Gene position: 890562-891260 (Clockwise)

Preceding gene: 183220275

Following gene: 183220277

Centisome position: 24.74

GC content: 43.2

Gene sequence:

>699_bases
ATGTCTGACCTTCCACTCATTCCCGATTGTTTTTTATGCGATTACAAAAACCATAATGTGTTGCATTGTGCGGCTCACGA
AACAATTGAACGAATCAACGCAGGGAAAGATTTTACGATGTTCCCTCGTGGCAAACACCTTGTGACAGCTGGGGTCAAAG
CTGACGGATTTTTTTTCATCAAAACAGGACTTGTCAGAAGTTATGTCCAACTCGCTAGCGGAAAAGAACAAACCCTCCGA
TTGAGTGGCCCTGGGGATTGGGTTGGGTTTCGCGATTGTATTTCTGATTCTATCTCTCATCACAACGTTGTGGCTGTGGA
AGACACTCATGCTTGTTACATCACAGGAGCTCTCATTGATGCTCTTGTCAAAGATGATAGTAACTTCCAAAAAGAAGTGT
TCCGCCAAATGGCCAAAGAATGGCGAGAAATGGAAGAACATGTTGTTTCTCTCGGAACCAAACAAGTCCATGAAAAATTA
GCAGAGATCCTCATCGTTTTGGACAATGCCCAAGGTCGTAAGAACCATGTGGAATTAAAGGTCACACGGGATGTCCTTGC
CACTTTCATTGGTACAAAAACGGAAACATTGGTCCGTGCCTTGTCGGATCTAAAGGCAAGGGAATTTATCTCAGTCGACA
AAAATCGAATCGATATTCTGAACAGAGAGGCATTGTATTCTCTCTCAAAAATCGCGTAA

Upstream 100 bases:

>100_bases
TAGAAAAGCGAGATCCTAAATTTAAGGGAAAATAAAATTTTAGAAAGTTTCTAAAATTTTGTCTCGACAAGCGACTGGTA
AGGGGTTACATAAAAGTTTG

Downstream 100 bases:

>100_bases
TTTTTTCTCCCAAGTGTTAAGCAAGAGCACTGGAATTCCGATGGTAGAAGTGATTGATAATCAAGGTAGGGTCTGTTGCC
TGATTTTACCTTAAATCACT

Product: CRP family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MSDLPLIPDCFLCDYKNHNVLHCAAHETIERINAGKDFTMFPRGKHLVTAGVKADGFFFIKTGLVRSYVQLASGKEQTLR
LSGPGDWVGFRDCISDSISHHNVVAVEDTHACYITGALIDALVKDDSNFQKEVFRQMAKEWREMEEHVVSLGTKQVHEKL
AEILIVLDNAQGRKNHVELKVTRDVLATFIGTKTETLVRALSDLKAREFISVDKNRIDILNREALYSLSKIA

Sequences:

>Translated_232_residues
MSDLPLIPDCFLCDYKNHNVLHCAAHETIERINAGKDFTMFPRGKHLVTAGVKADGFFFIKTGLVRSYVQLASGKEQTLR
LSGPGDWVGFRDCISDSISHHNVVAVEDTHACYITGALIDALVKDDSNFQKEVFRQMAKEWREMEEHVVSLGTKQVHEKL
AEILIVLDNAQGRKNHVELKVTRDVLATFIGTKTETLVRALSDLKAREFISVDKNRIDILNREALYSLSKIA
>Mature_231_residues
SDLPLIPDCFLCDYKNHNVLHCAAHETIERINAGKDFTMFPRGKHLVTAGVKADGFFFIKTGLVRSYVQLASGKEQTLRL
SGPGDWVGFRDCISDSISHHNVVAVEDTHACYITGALIDALVKDDSNFQKEVFRQMAKEWREMEEHVVSLGTKQVHEKLA
EILIVLDNAQGRKNHVELKVTRDVLATFIGTKTETLVRALSDLKAREFISVDKNRIDILNREALYSLSKIA

Specific function: Global transcription factor that controls the expression of over 100 target genes in response to anoxia. It facilitates the adaptation to anaerobic growth conditions by regulating the expression of gene products that are involved in anaerobic energy metab

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=191, Percent_Identity=25.6544502617801, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26111; Mature: 25980

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDLPLIPDCFLCDYKNHNVLHCAAHETIERINAGKDFTMFPRGKHLVTAGVKADGFFFI
CCCCCCCCCCEEEECCCCCEEEEHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCEEEE
KTGLVRSYVQLASGKEQTLRLSGPGDWVGFRDCISDSISHHNVVAVEDTHACYITGALID
HHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCEEEEHHHHHH
ALVKDDSNFQKEVFRQMAKEWREMEEHVVSLGTKQVHEKLAEILIVLDNAQGRKNHVELK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCCCCEEEEE
VTRDVLATFIGTKTETLVRALSDLKAREFISVDKNRIDILNREALYSLSKIA
EHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDLPLIPDCFLCDYKNHNVLHCAAHETIERINAGKDFTMFPRGKHLVTAGVKADGFFFI
CCCCCCCCCEEEECCCCCEEEEHHHHHHHHHCCCCCEEECCCCCEEEEECCCCCCEEEE
KTGLVRSYVQLASGKEQTLRLSGPGDWVGFRDCISDSISHHNVVAVEDTHACYITGALID
HHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCEEEEHHHHHH
ALVKDDSNFQKEVFRQMAKEWREMEEHVVSLGTKQVHEKLAEILIVLDNAQGRKNHVELK
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEECCCCCCCCEEEEE
VTRDVLATFIGTKTETLVRALSDLKAREFISVDKNRIDILNREALYSLSKIA
EHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA