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The map label for this gene is serB [C]

Identifier: 183220239

GI number: 183220239

Start: 844744

End: 845661

Strand: Direct

Name: serB [C]

Synonym: LEPBI_I0832

Alternate gene names: 183220239

Gene position: 844744-845661 (Clockwise)

Preceding gene: 183220238

Following gene: 183220245

Centisome position: 23.47

GC content: 39.98

Gene sequence:

>918_bases
ATGAATTCACTGCTTTTGATCTCTCGTTCCCCGATTCCTGATTCCATTTTACACAAAACATTCCCCACACACATTCGAAA
TGTGAGTGATCCGTCCTTCCAGGGGAATCAACCAAGTTCTGTTTCTCTTTCAAAGATTTTGTTTTCTAACAAGCTGGGAT
TACACTGTGTGAGAATCGAACGCAGTGAAACACTTAGCCGTGACCAAATTTTACACATTCGCGACGAATTGGCAAAGGAC
AAAATCGATTTTTTAGTTATCAATTCTTTGTTACCAAAATCAAAAGAATCTCTTTTTGTTTTTGATATGGATTCCACTGT
CATCAAGGAAGAAGTGATCGATGAACTCGCAAGAAAACATGGTGTGTATGAAGAAGTTGCGGGTGTGACAAAAAAAGCGA
TGGAGGGCGGTATGGGATTCGATGAAGCCCTAAGGCTTCGTGTAGCTCACCTTGCCGGTTTATCGATCCAAAGTTTTAAA
GAAGTATATGATGTATTACATTTAAACGATGGAATGGAAACTGTATTTCAGTTTGTTCCATCAAACGGATGTAAGCTTGG
AATCTTAAGTGGGGGATTTAGTCCCGTCCTCGAATTATTTTCAAATCAATATCCAGTGGATTTTTTTCGCGCAAATGGAC
TCGAAGAAAAGGGCGGCGTTTTTACAGGCCAAATCCACGGAGAAATCATCAACCGAGAAAAAAAAGAATTCTATTTAAAA
CAGTATGCAAGCGAACTTTCCATCCCGATCGAGAGGGTGGTGGCTGTTGGCGACGGAGCAAACGATGCACTTATGTTAAA
TGCCGCTGGCATTGGCATCGGAATCCATGCGAAACAAGGATTAAAGGACAAAATTACCAATTGGATTGAATTTACAGATT
TATCGGCTTTAATTTTCCTCTTGGAGAATTCGTTTTAA

Upstream 100 bases:

>100_bases
GTGAAGAGTTCATTCGTCCCAATGGCGACAGTTTACATTTTAATGAAAAAGGGTATGAAATTTGGGGTAAAAAATTACGA
CCTTATTTACAAAAATAAAA

Downstream 100 bases:

>100_bases
TTCATCTAAGATCGAAAGAGCCTCAAGAGGTGGAATTTTGTTTGGATCAATTTGAGAGATTCTTTTGATCACCTTTTCTT
CGTTTGCTGATAAACCATTT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNSLLLISRSPIPDSILHKTFPTHIRNVSDPSFQGNQPSSVSLSKILFSNKLGLHCVRIERSETLSRDQILHIRDELAKD
KIDFLVINSLLPKSKESLFVFDMDSTVIKEEVIDELARKHGVYEEVAGVTKKAMEGGMGFDEALRLRVAHLAGLSIQSFK
EVYDVLHLNDGMETVFQFVPSNGCKLGILSGGFSPVLELFSNQYPVDFFRANGLEEKGGVFTGQIHGEIINREKKEFYLK
QYASELSIPIERVVAVGDGANDALMLNAAGIGIGIHAKQGLKDKITNWIEFTDLSALIFLLENSF

Sequences:

>Translated_305_residues
MNSLLLISRSPIPDSILHKTFPTHIRNVSDPSFQGNQPSSVSLSKILFSNKLGLHCVRIERSETLSRDQILHIRDELAKD
KIDFLVINSLLPKSKESLFVFDMDSTVIKEEVIDELARKHGVYEEVAGVTKKAMEGGMGFDEALRLRVAHLAGLSIQSFK
EVYDVLHLNDGMETVFQFVPSNGCKLGILSGGFSPVLELFSNQYPVDFFRANGLEEKGGVFTGQIHGEIINREKKEFYLK
QYASELSIPIERVVAVGDGANDALMLNAAGIGIGIHAKQGLKDKITNWIEFTDLSALIFLLENSF
>Mature_305_residues
MNSLLLISRSPIPDSILHKTFPTHIRNVSDPSFQGNQPSSVSLSKILFSNKLGLHCVRIERSETLSRDQILHIRDELAKD
KIDFLVINSLLPKSKESLFVFDMDSTVIKEEVIDELARKHGVYEEVAGVTKKAMEGGMGFDEALRLRVAHLAGLSIQSFK
EVYDVLHLNDGMETVFQFVPSNGCKLGILSGGFSPVLELFSNQYPVDFFRANGLEEKGGVFTGQIHGEIINREKKEFYLK
QYASELSIPIERVVAVGDGANDALMLNAAGIGIGIHAKQGLKDKITNWIEFTDLSALIFLLENSF

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=225, Percent_Identity=28.8888888888889, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI1790849, Length=208, Percent_Identity=38.9423076923077, Blast_Score=135, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6321647, Length=211, Percent_Identity=34.1232227488152, Blast_Score=126, Evalue=4e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF01842 ACT; PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 33882; Mature: 33882

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSLLLISRSPIPDSILHKTFPTHIRNVSDPSFQGNQPSSVSLSKILFSNKLGLHCVRIE
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
RSETLSRDQILHIRDELAKDKIDFLVINSLLPKSKESLFVFDMDSTVIKEEVIDELARKH
CHHHCCHHHHHHHHHHHHHHHHHEEEEHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHC
GVYEEVAGVTKKAMEGGMGFDEALRLRVAHLAGLSIQSFKEVYDVLHLNDGMETVFQFVP
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCC
SNGCKLGILSGGFSPVLELFSNQYPVDFFRANGLEEKGGVFTGQIHGEIINREKKEFYLK
CCCCEEEEECCCHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
QYASELSIPIERVVAVGDGANDALMLNAAGIGIGIHAKQGLKDKITNWIEFTDLSALIFL
HHHHHHCCCHHHEEEECCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LENSF
HHCCC
>Mature Secondary Structure
MNSLLLISRSPIPDSILHKTFPTHIRNVSDPSFQGNQPSSVSLSKILFSNKLGLHCVRIE
CCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEC
RSETLSRDQILHIRDELAKDKIDFLVINSLLPKSKESLFVFDMDSTVIKEEVIDELARKH
CHHHCCHHHHHHHHHHHHHHHHHEEEEHHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHC
GVYEEVAGVTKKAMEGGMGFDEALRLRVAHLAGLSIQSFKEVYDVLHLNDGMETVFQFVP
CCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCC
SNGCKLGILSGGFSPVLELFSNQYPVDFFRANGLEEKGGVFTGQIHGEIINREKKEFYLK
CCCCEEEEECCCHHHHHHHHCCCCCCHHHCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHH
QYASELSIPIERVVAVGDGANDALMLNAAGIGIGIHAKQGLKDKITNWIEFTDLSALIFL
HHHHHHCCCHHHEEEECCCCCCEEEEEECCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
LENSF
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]