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The map label for this gene is tesA [C]

Identifier: 183220238

GI number: 183220238

Start: 844016

End: 844741

Strand: Direct

Name: tesA [C]

Synonym: LEPBI_I0831

Alternate gene names: 183220238

Gene position: 844016-844741 (Clockwise)

Preceding gene: 183220237

Following gene: 183220239

Centisome position: 23.45

GC content: 39.12

Gene sequence:

>726_bases
GTGTCTATCGCCCTGGTTTTGAGTGTTACCAATTGTAATTCCACCTCAAAACGAGATTACTTCGACTCTAATTTTAAGTG
TTTTGCGGAACCAGGTTGGCGTGATGATGCCAATTTCAAAAAGTATATAGAGAAAGCTTGGCTCCCCACACGCCTGTTAT
ACGCTAAAGACAATTCCAAAATCAAACGATCCGATATTGTTTTTACAGGAGATAGTTTGGTACATTTGTTTTTACCAAAC
CTCATGGCAAAAGAATTTCCTGGAAAGTCTGTTACCAATCGTGGGATTGGTGGAGATATGTCAGAAACTCTCCTCTCTCG
CATTGATGATGATGTGTTACGCCTAGAACCAAAAACAGTCGTCATTGAAATTGGCGGAAATGATTTCATCCAGGGGAAAT
GTTTGAGTCTTGTGCAAAACAATTTACTTTCCATCATCAAAAAAATCCATTCACGCAACCATCAAATCCGAATCTTTTTA
ATTGCGGTTCCACCCACTCGAGTGAAGGAACTCAATCAGATTGTACCTGTTTACAATTTGTTTTTAAACCAAGTCGCAAG
GACCACGCAGAATGTTGAATACATTGAAGTTTGGGACATCATGCGGAAACCGGATGCACCCACACTCAGTGAAGAGTTCA
TTCGTCCCAATGGCGACAGTTTACATTTTAATGAAAAAGGGTATGAAATTTGGGGTAAAAAATTACGACCTTATTTACAA
AAATAA

Upstream 100 bases:

>100_bases
GACACGGAAGAATATGCGCAGGCCCAGATCAAAGATTGGCAAAAGCGCTTCCGAATGAATGAACCACAAGAACAGGATTA
AATTCTTCCTTCGATGGGGC

Downstream 100 bases:

>100_bases
AAATGAATTCACTGCTTTTGATCTCTCGTTCCCCGATTCCTGATTCCATTTTACACAAAACATTCCCCACACACATTCGA
AATGTGAGTGATCCGTCCTT

Product: putative hydrolase

Products: @ACYL02.txt*Glycerophosphocholine!; A Fatty Acid Anion. [C]

Alternate protein names: Lipase/Phospolipase; Lipolytic Protein G-D-S-L Family; Platelet-Activating Factor Acetylhydrolase IB Gamma Subunit; GDSL-Like Lipase/Acylhydrolase Family Protein; Lipase/Acylhydrolase; GDSL Family Lipase; SGNH-Hydrolase; Platelet Activating Factor; Lipase/Acylhydrolase Family Protein; GDSL-Like Lipase/Acylhydrolase Domain Protein; Secreted Protein

Number of amino acids: Translated: 241; Mature: 240

Protein sequence:

>241_residues
MSIALVLSVTNCNSTSKRDYFDSNFKCFAEPGWRDDANFKKYIEKAWLPTRLLYAKDNSKIKRSDIVFTGDSLVHLFLPN
LMAKEFPGKSVTNRGIGGDMSETLLSRIDDDVLRLEPKTVVIEIGGNDFIQGKCLSLVQNNLLSIIKKIHSRNHQIRIFL
IAVPPTRVKELNQIVPVYNLFLNQVARTTQNVEYIEVWDIMRKPDAPTLSEEFIRPNGDSLHFNEKGYEIWGKKLRPYLQ
K

Sequences:

>Translated_241_residues
MSIALVLSVTNCNSTSKRDYFDSNFKCFAEPGWRDDANFKKYIEKAWLPTRLLYAKDNSKIKRSDIVFTGDSLVHLFLPN
LMAKEFPGKSVTNRGIGGDMSETLLSRIDDDVLRLEPKTVVIEIGGNDFIQGKCLSLVQNNLLSIIKKIHSRNHQIRIFL
IAVPPTRVKELNQIVPVYNLFLNQVARTTQNVEYIEVWDIMRKPDAPTLSEEFIRPNGDSLHFNEKGYEIWGKKLRPYLQ
K
>Mature_240_residues
SIALVLSVTNCNSTSKRDYFDSNFKCFAEPGWRDDANFKKYIEKAWLPTRLLYAKDNSKIKRSDIVFTGDSLVHLFLPNL
MAKEFPGKSVTNRGIGGDMSETLLSRIDDDVLRLEPKTVVIEIGGNDFIQGKCLSLVQNNLLSIIKKIHSRNHQIRIFLI
AVPPTRVKELNQIVPVYNLFLNQVARTTQNVEYIEVWDIMRKPDAPTLSEEFIRPNGDSLHFNEKGYEIWGKKLRPYLQK

Specific function: Hydrolyzes Only Long Chain Acyl Thioesters (C12-C18). Specificity Similar To Chymotrypsin. [C]

COG id: COG2755

COG function: function code E; Lysophospholipase L1 and related esterases

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.1.2.- [C]

Molecular weight: Translated: 27719; Mature: 27588

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIALVLSVTNCNSTSKRDYFDSNFKCFAEPGWRDDANFKKYIEKAWLPTRLLYAKDNSK
CEEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCC
IKRSDIVFTGDSLVHLFLPNLMAKEFPGKSVTNRGIGGDMSETLLSRIDDDVLRLEPKTV
EEECEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHEEECCCEE
VIEIGGNDFIQGKCLSLVQNNLLSIIKKIHSRNHQIRIFLIAVPPTRVKELNQIVPVYNL
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHH
FLNQVARTTQNVEYIEVWDIMRKPDAPTLSEEFIRPNGDSLHFNEKGYEIWGKKLRPYLQ
HHHHHHHHHCCCCEEEEHHHHCCCCCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHC
K
C
>Mature Secondary Structure 
SIALVLSVTNCNSTSKRDYFDSNFKCFAEPGWRDDANFKKYIEKAWLPTRLLYAKDNSK
EEEEEEEEECCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCC
IKRSDIVFTGDSLVHLFLPNLMAKEFPGKSVTNRGIGGDMSETLLSRIDDDVLRLEPKTV
EEECEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCHHEEECCCEE
VIEIGGNDFIQGKCLSLVQNNLLSIIKKIHSRNHQIRIFLIAVPPTRVKELNQIVPVYNL
EEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHHHHH
FLNQVARTTQNVEYIEVWDIMRKPDAPTLSEEFIRPNGDSLHFNEKGYEIWGKKLRPYLQ
HHHHHHHHHCCCCEEEEHHHHCCCCCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Lysophosphatidiylcholine; H2O [C]

Specific reaction: 2-Lysophosphatidiylcholine + H2O = @ACYL02.txt*Glycerophosphocholine! + A Fatty Acid Anion. [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA