Click here to switch to the map view.

The map label for this gene is groES

Identifier: 18311272

GI number: 18311272

Start: 2635664

End: 2635948

Strand: Reverse

Name: groES

Synonym: CPE2290

Alternate gene names: 18311272

Gene position: 2635948-2635664 (Counterclockwise)

Preceding gene: 18311275

Following gene: 18311271

Centisome position: 86.95

GC content: 35.79

Gene sequence:

>285_bases
ATGAGTATTAAACCACTTGGAGACAGGGTTGTTATTAAAAGATTAGAAGCAGAAGAAACTACTAAAAGCGGTATAATAGT
TACTGGAACTGCTAAGGAAAGACCACAAGAAGCAGAGGTTGTTGCAGTGGGACCAGGAGCGATAGTTGATGGAAAAAGAA
CAGAGATGGAAGTTAAAATAGGAGATAAAGTATTATATTCTAAATATGCAGGAACAGAAGTTAAGTTCGAGGGGGAAGAA
TATACTATTTTAAGACAAGACGATATACTAGCAATAGTTGAATAG

Upstream 100 bases:

>100_bases
ATTTACAACTGGTAAATTATATGATAATAGTAAGAATTAGCACTCTATATTAATGAGTGCTAAACAAAAATTAATTAGCA
TTTTTAAGGAGGGTTTTTTA

Downstream 100 bases:

>100_bases
TTTTAAAATATAAGTGATTTAGATATTCATAATATATTTGGGAGGTAAATTAATATGGCTAAAACATTATTATTCGGTGA
AGAAGCAAGAAGATCTATGC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MSIKPLGDRVVIKRLEAEETTKSGIIVTGTAKERPQEAEVVAVGPGAIVDGKRTEMEVKIGDKVLYSKYAGTEVKFEGEE
YTILRQDDILAIVE

Sequences:

>Translated_94_residues
MSIKPLGDRVVIKRLEAEETTKSGIIVTGTAKERPQEAEVVAVGPGAIVDGKRTEMEVKIGDKVLYSKYAGTEVKFEGEE
YTILRQDDILAIVE
>Mature_93_residues
SIKPLGDRVVIKRLEAEETTKSGIIVTGTAKERPQEAEVVAVGPGAIVDGKRTEMEVKIGDKVLYSKYAGTEVKFEGEEY
TILRQDDILAIVE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=42.7083333333333, Blast_Score=74, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=39.3617021276596, Blast_Score=66, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=40.2173913043478, Blast_Score=66, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21356029, Length=96, Percent_Identity=40.625, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_CLOP1 (Q0TN26)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696964.1
- ProteinModelPortal:   Q0TN26
- SMR:   Q0TN26
- STRING:   Q0TN26
- GeneID:   4203708
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2574
- TIGR:   CPF_2574
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   GFVIAGN
- ProtClustDB:   PRK00364
- BioCyc:   CPER195103:CPF_2574-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10308; Mature: 10177

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIKPLGDRVVIKRLEAEETTKSGIIVTGTAKERPQEAEVVAVGPGAIVDGKRTEMEVKI
CCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEEECCCEEECCCCEEEEEEE
GDKVLYSKYAGTEVKFEGEEYTILRQDDILAIVE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure 
SIKPLGDRVVIKRLEAEETTKSGIIVTGTAKERPQEAEVVAVGPGAIVDGKRTEMEVKI
CCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEEECCCEEECCCCEEEEEEE
GDKVLYSKYAGTEVKFEGEEYTILRQDDILAIVE
CCEEEEEECCCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA