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The map label for this gene is atpI [H]

Identifier: 18311175

GI number: 18311175

Start: 2513517

End: 2514191

Strand: Reverse

Name: atpI [H]

Synonym: CPE2193

Alternate gene names: 18311175

Gene position: 2514191-2513517 (Counterclockwise)

Preceding gene: 18311176

Following gene: 18311174

Centisome position: 82.94

GC content: 31.41

Gene sequence:

>675_bases
GTGGATATCTTTGCACCATTGTTTACAGTTAAGATTGGTAGTTTGACAATAAGCAGTACAATTATTTTTCAATGGGCAGC
AATGCTTCTTATAATAGTTTTTGCTTTATTATCAACTAGAAATCTTAAAAATAAACCAGGTAAGTTACAAGTTGTTTTAG
AATCAATCTATCAAACAGTTTATAACTTAGTAAAGAGCAACATGGGGGAAAGTTATATTGGTTTTGTGCCTTATATAGGA
ACTTTAGCAATATTCCTACTTGTATTAAACTTTTATGGGTTAATAGGGCTTGCACCTCCTACTCAAGATTTAAGTGTTGC
AGTGGCATTAGCAATTACTTCCTTTGTTGTTGTTCATGTTAATGCTATACGTAGATGTCATATTGGAGGATATATCAAAG
GATATTTTAAGCCTTATCCACTAATGTTACCTTTAAACTTAATGGAGAGAATTATTTTCCCAGTATCTCTTGCACTACGT
TTATTCGGTAATATGCTAGCAGCTACCTTATTAATAGACTTAATGTATTCAGGTTTAGGACACATAAGTTGGTTTGCTCA
ATTAGGTATGCCAATACTAGCACATGGTTTCTTCGATGTATTTGATGGAACAATACAAATGATAGTATTTACTATGTTAA
CTATGGTAAATATTAAAATTATAGCAGATCACTAA

Upstream 100 bases:

>100_bases
ATATTTATTTATACTAAAAAAATAAGGCCTTATAAAAAACAATAAATAAATATTTATATACATATATAAATTAATACTAA
GATAGAAAGGGAGTGATTCC

Downstream 100 bases:

>100_bases
GAAAAGTTAATTAAACAAATCAAAGTAACTTTATTTGATTTGAAAAAGGAGGAATTTTTAATGGATATGAAGTTATTAGC
AGCAGGTATCGCTGTATTAG

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MDIFAPLFTVKIGSLTISSTIIFQWAAMLLIIVFALLSTRNLKNKPGKLQVVLESIYQTVYNLVKSNMGESYIGFVPYIG
TLAIFLLVLNFYGLIGLAPPTQDLSVAVALAITSFVVVHVNAIRRCHIGGYIKGYFKPYPLMLPLNLMERIIFPVSLALR
LFGNMLAATLLIDLMYSGLGHISWFAQLGMPILAHGFFDVFDGTIQMIVFTMLTMVNIKIIADH

Sequences:

>Translated_224_residues
MDIFAPLFTVKIGSLTISSTIIFQWAAMLLIIVFALLSTRNLKNKPGKLQVVLESIYQTVYNLVKSNMGESYIGFVPYIG
TLAIFLLVLNFYGLIGLAPPTQDLSVAVALAITSFVVVHVNAIRRCHIGGYIKGYFKPYPLMLPLNLMERIIFPVSLALR
LFGNMLAATLLIDLMYSGLGHISWFAQLGMPILAHGFFDVFDGTIQMIVFTMLTMVNIKIIADH
>Mature_224_residues
MDIFAPLFTVKIGSLTISSTIIFQWAAMLLIIVFALLSTRNLKNKPGKLQVVLESIYQTVYNLVKSNMGESYIGFVPYIG
TLAIFLLVLNFYGLIGLAPPTQDLSVAVALAITSFVVVHVNAIRRCHIGGYIKGYFKPYPLMLPLNLMERIIFPVSLALR
LFGNMLAATLLIDLMYSGLGHISWFAQLGMPILAHGFFDVFDGTIQMIVFTMLTMVNIKIIADH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 24866; Mature: 24866

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIFAPLFTVKIGSLTISSTIIFQWAAMLLIIVFALLSTRNLKNKPGKLQVVLESIYQTV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
YNLVKSNMGESYIGFVPYIGTLAIFLLVLNFYGLIGLAPPTQDLSVAVALAITSFVVVHV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
NAIRRCHIGGYIKGYFKPYPLMLPLNLMERIIFPVSLALRLFGNMLAATLLIDLMYSGLG
HHHHHHHCCCHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HISWFAQLGMPILAHGFFDVFDGTIQMIVFTMLTMVNIKIIADH
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC
>Mature Secondary Structure
MDIFAPLFTVKIGSLTISSTIIFQWAAMLLIIVFALLSTRNLKNKPGKLQVVLESIYQTV
CCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
YNLVKSNMGESYIGFVPYIGTLAIFLLVLNFYGLIGLAPPTQDLSVAVALAITSFVVVHV
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
NAIRRCHIGGYIKGYFKPYPLMLPLNLMERIIFPVSLALRLFGNMLAATLLIDLMYSGLG
HHHHHHHCCCHHHHCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HISWFAQLGMPILAHGFFDVFDGTIQMIVFTMLTMVNIKIIADH
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10902917; 11466286 [H]