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The map label for this gene is ipk

Identifier: 182682631

GI number: 182682631

Start: 2389765

End: 2390643

Strand: Reverse

Name: ipk

Synonym: XfasM23_2119

Alternate gene names: 182682631

Gene position: 2390643-2389765 (Counterclockwise)

Preceding gene: 182682632

Following gene: 182682630

Centisome position: 94.28

GC content: 54.15

Gene sequence:

>879_bases
GTGAGTGTCGTCATTGATGACGGTGTGGGCTGGTCGGCGTGGCCGGCACCTGCCAAGTTGAATTTATTTTTGCAAATTAC
CGGGCGACGTGTTGATGGTTACCATGAATTGCAGACTGTTTTTCGTCTGCTTGATTGGGGTGATACGATCCATCTGCGGG
TGCGTGAAGATGGTCAGATTCATCGCATTGGTGAGTCAGTGACTGGGGTTGTTGAGGCTGACGACTTGGTGGTGCGTGCG
GCTTATTTGCTAAAACATGCGACTAATGTCTATTTAGGGGCAGATATCTTTGTTGAAAAGCGAATCCCAGTTGGTGGCGG
CTTTGGCGGTGGGTCCTCTGATGCGGCGACTGTGCTTCTTGTGTTGAATGCATTGTGGCACACCAGGCTTGACGTTGCGG
TTTTGGCGGCTTTGGGGTTACGTTTGGGGGCCGATGTGCCGGTATTTGTACATGGGTGTAATGCGTGGGCTGAGGGTGTC
GGTGAGTGCTTAACACCGATGATTCTGCCTGGAGCGGCCTACCTGCTATTGGATCCAGGGGTGTGTGTGCCGACACGGGA
GCTGTTCCTTGATCCGGATTTGACGCGCGATGCGTCCCCCGCGACAATAGGCGACTTCATTGCTGGTACTGCGTTTGGTA
ATGCATTCGAGCCGGTTCTGAGACGCCGCGAGTCTGCGGTTGCGGGTGCTCTTGATGTGCTCTCAGAGGTTGGTTTTGCA
AGGGTGACTGGCTCTGGCAGCGGTTGCTTTGTGGAATTCAGTACGCGCGATGAGGCTGAGTGTGCTTTGGAGCGGCTGCC
GTACGGGTTGTGTGCTTGGGTTGCTGATGGCGCTTCCCGTTCTCCGCTGCTTGATGTACTGAAAACAATGGAATTTTGA

Upstream 100 bases:

>100_bases
CGTCTTCCGTGGGGCGTCCGATGTTGCCGCGGCAAATTGAGGCTAGTCGCGGTTCGGCTAGGATACGTTTGATTGTTGAT
CAATGGGACGAGTTGATCCC

Downstream 100 bases:

>100_bases
TGCAGGGGCGTCGCCAAGAGGACTAAGGCACCGGGTTTTGATCCCGGCATTCGTAGGTTCGAATCCTACCGCCCCTGCCA
GTTTTTTTATGGTTTTCAAG

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSVVIDDGVGWSAWPAPAKLNLFLQITGRRVDGYHELQTVFRLLDWGDTIHLRVREDGQIHRIGESVTGVVEADDLVVRA
AYLLKHATNVYLGADIFVEKRIPVGGGFGGGSSDAATVLLVLNALWHTRLDVAVLAALGLRLGADVPVFVHGCNAWAEGV
GECLTPMILPGAAYLLLDPGVCVPTRELFLDPDLTRDASPATIGDFIAGTAFGNAFEPVLRRRESAVAGALDVLSEVGFA
RVTGSGSGCFVEFSTRDEAECALERLPYGLCAWVADGASRSPLLDVLKTMEF

Sequences:

>Translated_292_residues
MSVVIDDGVGWSAWPAPAKLNLFLQITGRRVDGYHELQTVFRLLDWGDTIHLRVREDGQIHRIGESVTGVVEADDLVVRA
AYLLKHATNVYLGADIFVEKRIPVGGGFGGGSSDAATVLLVLNALWHTRLDVAVLAALGLRLGADVPVFVHGCNAWAEGV
GECLTPMILPGAAYLLLDPGVCVPTRELFLDPDLTRDASPATIGDFIAGTAFGNAFEPVLRRRESAVAGALDVLSEVGFA
RVTGSGSGCFVEFSTRDEAECALERLPYGLCAWVADGASRSPLLDVLKTMEF
>Mature_291_residues
SVVIDDGVGWSAWPAPAKLNLFLQITGRRVDGYHELQTVFRLLDWGDTIHLRVREDGQIHRIGESVTGVVEADDLVVRAA
YLLKHATNVYLGADIFVEKRIPVGGGFGGGSSDAATVLLVLNALWHTRLDVAVLAALGLRLGADVPVFVHGCNAWAEGVG
ECLTPMILPGAAYLLLDPGVCVPTRELFLDPDLTRDASPATIGDFIAGTAFGNAFEPVLRRRESAVAGALDVLSEVGFAR
VTGSGSGCFVEFSTRDEAECALERLPYGLCAWVADGASRSPLLDVLKTMEF

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=278, Percent_Identity=49.6402877697842, Blast_Score=223, Evalue=8e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 31191; Mature: 31060

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVVIDDGVGWSAWPAPAKLNLFLQITGRRVDGYHELQTVFRLLDWGDTIHLRVREDGQI
CEEEEECCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCE
HRIGESVTGVVEADDLVVRAAYLLKHATNVYLGADIFVEKRIPVGGGFGGGSSDAATVLL
EECCCHHCCEEEHHHHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCCCCCCHHHHHHHH
VLNALWHTRLDVAVLAALGLRLGADVPVFVHGCNAWAEGVGECLTPMILPGAAYLLLDPG
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCC
VCVPTRELFLDPDLTRDASPATIGDFIAGTAFGNAFEPVLRRRESAVAGALDVLSEVGFA
CCCCCHHHEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEE
RVTGSGSGCFVEFSTRDEAECALERLPYGLCAWVADGASRSPLLDVLKTMEF
EEECCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SVVIDDGVGWSAWPAPAKLNLFLQITGRRVDGYHELQTVFRLLDWGDTIHLRVREDGQI
EEEEECCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCE
HRIGESVTGVVEADDLVVRAAYLLKHATNVYLGADIFVEKRIPVGGGFGGGSSDAATVLL
EECCCHHCCEEEHHHHHHHHHHHHHHHCCEEECCEEEEEECCCCCCCCCCCCHHHHHHHH
VLNALWHTRLDVAVLAALGLRLGADVPVFVHGCNAWAEGVGECLTPMILPGAAYLLLDPG
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCEEEEECCC
VCVPTRELFLDPDLTRDASPATIGDFIAGTAFGNAFEPVLRRRESAVAGALDVLSEVGFA
CCCCCHHHEECCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCEE
RVTGSGSGCFVEFSTRDEAECALERLPYGLCAWVADGASRSPLLDVLKTMEF
EEECCCCEEEEEECCCCHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]