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The map label for this gene is lolB

Identifier: 182682632

GI number: 182682632

Start: 2390640

End: 2391296

Strand: Reverse

Name: lolB

Synonym: XfasM23_2120

Alternate gene names: 182682632

Gene position: 2391296-2390640 (Counterclockwise)

Preceding gene: 182682633

Following gene: 182682631

Centisome position: 94.31

GC content: 56.93

Gene sequence:

>657_bases
ATGAAGGTGTATTTGCATGATGTGAATAGGGGCTTGGGTGTGTTCTTGTTGGCAGTCTCTTTTTTGTTGCCTGGGTGTAG
CAGCAGTGGTGGCCGGCGTGCGTCGGTGCCCGTCACGGTGGATGCCACTGCGCAGGTAGTTGAGCAGGCTCGCCAAACGT
GGTTGCAGGAGCATCCTAACTGGAGTTTTTACGGACGTGCGGCGATCAGGCAGGGGAGTGATGGTGGGAGTGTCCGGGTG
GAGTGGGAGCAGCATGGTCGCGGTTACCGCATTGTGTTAAGTGCTCCAATGAGTCGTCAGAGTTGGGTGTTGAGCGGAAG
TAGTAGCGGTCCGGCTCGTCTTGAGGGTGTGGGTGGGTGGGTGCGTGTTGGCGAAGTTGCCGAACAGGTGTTGTTCGAGG
CGACTGGTTGGCAAGTTCCGATGGGGTTATTGCCTGATTGGGTACGAGGTCGCAATAGTGATAGTGGGGGTGGGGATGTG
CAGTTAGATGCGGAGGGACGTCCTCACCGTGTGTATCAGGGGGGGTGGCAGTTGAGGTTTCTGGATTGGTTTCCGTCTTC
CGTGGGGCGTCCGATGTTGCCGCGGCAAATTGAGGCTAGTCGCGGTTCGGCTAGGATACGTTTGATTGTTGATCAATGGG
ACGAGTTGATCCCGTGA

Upstream 100 bases:

>100_bases
CGGATGGTCAGCGCGAGGAGGCACGGTACTATTTTGAGGAAGCGCGTAAATTGGATCCGGATAATTTGGTGTTGCGCCAT
GTACTGGAAAAGTTTGGGTT

Downstream 100 bases:

>100_bases
GTGTCGTCATTGATGACGGTGTGGGCTGGTCGGCGTGGCCGGCACCTGCCAAGTTGAATTTATTTTTGCAAATTACCGGG
CGACGTGTTGATGGTTACCA

Product: outer membrane lipoprotein LolB

Products: 5-aminolevulinate; CoA; CO2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKVYLHDVNRGLGVFLLAVSFLLPGCSSSGGRRASVPVTVDATAQVVEQARQTWLQEHPNWSFYGRAAIRQGSDGGSVRV
EWEQHGRGYRIVLSAPMSRQSWVLSGSSSGPARLEGVGGWVRVGEVAEQVLFEATGWQVPMGLLPDWVRGRNSDSGGGDV
QLDAEGRPHRVYQGGWQLRFLDWFPSSVGRPMLPRQIEASRGSARIRLIVDQWDELIP

Sequences:

>Translated_218_residues
MKVYLHDVNRGLGVFLLAVSFLLPGCSSSGGRRASVPVTVDATAQVVEQARQTWLQEHPNWSFYGRAAIRQGSDGGSVRV
EWEQHGRGYRIVLSAPMSRQSWVLSGSSSGPARLEGVGGWVRVGEVAEQVLFEATGWQVPMGLLPDWVRGRNSDSGGGDV
QLDAEGRPHRVYQGGWQLRFLDWFPSSVGRPMLPRQIEASRGSARIRLIVDQWDELIP
>Mature_218_residues
MKVYLHDVNRGLGVFLLAVSFLLPGCSSSGGRRASVPVTVDATAQVVEQARQTWLQEHPNWSFYGRAAIRQGSDGGSVRV
EWEQHGRGYRIVLSAPMSRQSWVLSGSSSGPARLEGVGGWVRVGEVAEQVLFEATGWQVPMGLLPDWVRGRNSDSGGGDV
QLDAEGRPHRVYQGGWQLRFLDWFPSSVGRPMLPRQIEASRGSARIRLIVDQWDELIP

Specific function: Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the lolA protein

COG id: COG3017

COG function: function code M; Outer membrane lipoprotein involved in outer membrane biogenesis

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LOLB_XYLFT (Q87A20)

Other databases:

- EMBL:   AE009442
- RefSeq:   NP_780194.1
- ProteinModelPortal:   Q87A20
- SMR:   Q87A20
- STRING:   Q87A20
- GeneID:   1143361
- GenomeReviews:   AE009442_GR
- KEGG:   xft:PD2019
- eggNOG:   COG3017
- HOGENOM:   HBG701397
- OMA:   RIEASNG
- ProtClustDB:   PRK00022
- BioCyc:   XFAS183190:PD_2019-MONOMER
- HAMAP:   MF_00233
- InterPro:   IPR004565
- TIGRFAMs:   TIGR00548

Pfam domain/function: PF03550 LolB

EC number: NA

Molecular weight: Translated: 24063; Mature: 24063

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS51257 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYLHDVNRGLGVFLLAVSFLLPGCSSSGGRRASVPVTVDATAQVVEQARQTWLQEHPN
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEECCCEEECHHHHHHHHHHHHHHHHCCC
WSFYGRAAIRQGSDGGSVRVEWEQHGRGYRIVLSAPMSRQSWVLSGSSSGPARLEGVGGW
CCEEEEEEEECCCCCCEEEEEEHHCCCCEEEEEECCCCCCEEEEECCCCCCCEEECCCCE
VRVGEVAEQVLFEATGWQVPMGLLPDWVRGRNSDSGGGDVQLDAEGRPHRVYQGGWQLRF
EHHHHHHHHHHHHCCCCCCCHHCCCHHHCCCCCCCCCCEEEECCCCCCCEEECCCEEEEE
LDWFPSSVGRPMLPRQIEASRGSARIRLIVDQWDELIP
EECCCHHCCCCCCCCHHCCCCCCEEEEEEEECHHHHCC
>Mature Secondary Structure
MKVYLHDVNRGLGVFLLAVSFLLPGCSSSGGRRASVPVTVDATAQVVEQARQTWLQEHPN
CEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEECCCEEECHHHHHHHHHHHHHHHHCCC
WSFYGRAAIRQGSDGGSVRVEWEQHGRGYRIVLSAPMSRQSWVLSGSSSGPARLEGVGGW
CCEEEEEEEECCCCCCEEEEEEHHCCCCEEEEEECCCCCCEEEEECCCCCCCEEECCCCE
VRVGEVAEQVLFEATGWQVPMGLLPDWVRGRNSDSGGGDVQLDAEGRPHRVYQGGWQLRF
EHHHHHHHHHHHHCCCCCCCHHCCCHHHCCCCCCCCCCEEEECCCCCCCEEECCCEEEEE
LDWFPSSVGRPMLPRQIEASRGSARIRLIVDQWDELIP
EECCCHHCCCCCCCCHHCCCCCCEEEEEEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Succinyl-CoA; glycine [C]

Specific reaction: Succinyl-CoA + glycine = 5-aminolevulinate + CoA + CO2 [C]

General reaction: Acyltransferases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12533478