Click here to switch to the map view.

The map label for this gene is phoR [H]

Identifier: 182682585

GI number: 182682585

Start: 2331517

End: 2332857

Strand: Reverse

Name: phoR [H]

Synonym: XfasM23_2073

Alternate gene names: 182682585

Gene position: 2332857-2331517 (Counterclockwise)

Preceding gene: 182682586

Following gene: 182682584

Centisome position: 92.0

GC content: 52.27

Gene sequence:

>1341_bases
GTGAGTATCGTCTCCACACTCCACCGTATTCGGTTCGCTTGGTTCAAGACCCTGGGAGTGTTGGCGCTGATTTTGTTCGC
TGCACTGCTTGTTGGTCTGTTGATCGGCCAAGTGTGGATAGTACTGACCTTAACAGCCTTAGCAGAAATTGCCTGGCAGT
ACTGGAGGCTGCATCAAGTTCTGTATCAATTGGCCGTGCGTCGGCGCTGGACACGTTCGATGGATATCGGTGTTTGGAAA
CAATTAGATCACTTGATTTACCGTAATCAAACCGACATGCGTGCGCGTGTTCACCGGTTGATGGAGATGTTGCGTACCTA
CCGTGCAGCAGCAGCTGCGCTCCCTGATGCAGTGGTTGTTGTCGATTGCAATAGTCAGTGCATTCAATGGTTCAATGAGG
CGGCGAATACCTTGCTGGGCCTGCGTTACCCTAGCGACCTGGACAGGCCTGTTGTCGAGCGGTTGCAGCCGTTGCCGTTA
GCATCATGGTTGACTCAGGGTTGTAACGCTGAGTCGATGTTGGACGTGCCTTCACCAGTGAATCCTGACGTGCGCTTGAA
TCTGCACCTCATTCCTTATTTCGACGATTATTTGTTGCTGGTAGCACGTGACGTTAGCAAACTGTTGCGTCTGGAGCAGG
TGAAACGTGACTTTGTGGCGAATGTGTCGCACGAATTACGTACCCCATTGACCGTGGTGCATGGTTATCTTGACATGCTC
GATCCGGATGATTTTCCGGATGCTGCTCCAATGTTGGATGAGATGCGTAAGCAGTCGCAGCGCATGACTCAATTAGTTGA
GGATCTGCTGACACTCTCCAGGTTGGAATCCCAGGAGGAACTTGAACAGGAGCAGGTGGCAATGGTGCCGATGTTGGCGA
CGTTGCATCGTGAGGCTGAGGCACACAGTCAAGGCCGTCATACGATTGAAGTGGTCGACAATGCTGGCTGCGATCTTTTC
GGCTCCAATAAGGACCTTCACAGTGCGTTTTCCAATTTGATTACCAACGCAGTGCGTTACACTCCGGCTGGCGGTAGTGT
TAGGGTGTGCTTCCAACGCGAAGATGATGGCGTGGCGCTGATGGTTTGCGATACTGGTTATGGTATTCCAACCTCACACT
TACCACGAATCACCGAACGCTTTTACCGGGTTTCCAGCAGTCGCTCGCGTGAGAGAGGGGGGACTGGTTTAGGGCTGTCG
ATCGTCAAGCATGTGTTGGAACTCCACCAGGCACGCTTAGACATCATCAGTGAAGTTGGTAAGGGGAGTGAATTCTCCTG
CCACTTTGCTGCAGCCCGAGTCGCCATGCGTGAATCTGAATCTGTGCCGATACAGCCTTAG

Upstream 100 bases:

>100_bases
CGTTGGAGCCATTCGGCCTTGACGATATGGTGCAGACGGTACGTAGTGCCGGTTATCGCTTCTCCGGGGCGATCCAGATC
TGAATATTCCATCGAATGCC

Downstream 100 bases:

>100_bases
ATGTCCCTGCTTGAAATAATCCTTGCTCGTGTGGCGTGGATTTACTGTGGCCTCACTGTTGTTCCTTCCTACTTATATTT
CTTTCCTAGTCTCTTTTTTC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 446; Mature: 445

Protein sequence:

>446_residues
MSIVSTLHRIRFAWFKTLGVLALILFAALLVGLLIGQVWIVLTLTALAEIAWQYWRLHQVLYQLAVRRRWTRSMDIGVWK
QLDHLIYRNQTDMRARVHRLMEMLRTYRAAAAALPDAVVVVDCNSQCIQWFNEAANTLLGLRYPSDLDRPVVERLQPLPL
ASWLTQGCNAESMLDVPSPVNPDVRLNLHLIPYFDDYLLLVARDVSKLLRLEQVKRDFVANVSHELRTPLTVVHGYLDML
DPDDFPDAAPMLDEMRKQSQRMTQLVEDLLTLSRLESQEELEQEQVAMVPMLATLHREAEAHSQGRHTIEVVDNAGCDLF
GSNKDLHSAFSNLITNAVRYTPAGGSVRVCFQREDDGVALMVCDTGYGIPTSHLPRITERFYRVSSSRSRERGGTGLGLS
IVKHVLELHQARLDIISEVGKGSEFSCHFAAARVAMRESESVPIQP

Sequences:

>Translated_446_residues
MSIVSTLHRIRFAWFKTLGVLALILFAALLVGLLIGQVWIVLTLTALAEIAWQYWRLHQVLYQLAVRRRWTRSMDIGVWK
QLDHLIYRNQTDMRARVHRLMEMLRTYRAAAAALPDAVVVVDCNSQCIQWFNEAANTLLGLRYPSDLDRPVVERLQPLPL
ASWLTQGCNAESMLDVPSPVNPDVRLNLHLIPYFDDYLLLVARDVSKLLRLEQVKRDFVANVSHELRTPLTVVHGYLDML
DPDDFPDAAPMLDEMRKQSQRMTQLVEDLLTLSRLESQEELEQEQVAMVPMLATLHREAEAHSQGRHTIEVVDNAGCDLF
GSNKDLHSAFSNLITNAVRYTPAGGSVRVCFQREDDGVALMVCDTGYGIPTSHLPRITERFYRVSSSRSRERGGTGLGLS
IVKHVLELHQARLDIISEVGKGSEFSCHFAAARVAMRESESVPIQP
>Mature_445_residues
SIVSTLHRIRFAWFKTLGVLALILFAALLVGLLIGQVWIVLTLTALAEIAWQYWRLHQVLYQLAVRRRWTRSMDIGVWKQ
LDHLIYRNQTDMRARVHRLMEMLRTYRAAAAALPDAVVVVDCNSQCIQWFNEAANTLLGLRYPSDLDRPVVERLQPLPLA
SWLTQGCNAESMLDVPSPVNPDVRLNLHLIPYFDDYLLLVARDVSKLLRLEQVKRDFVANVSHELRTPLTVVHGYLDMLD
PDDFPDAAPMLDEMRKQSQRMTQLVEDLLTLSRLESQEELEQEQVAMVPMLATLHREAEAHSQGRHTIEVVDNAGCDLFG
SNKDLHSAFSNLITNAVRYTPAGGSVRVCFQREDDGVALMVCDTGYGIPTSHLPRITERFYRVSSSRSRERGGTGLGLSI
VKHVLELHQARLDIISEVGKGSEFSCHFAAARVAMRESESVPIQP

Specific function: Member of the two-component regulatory system phoR/phoB involved in the phosphate regulon genes expression. PhoR may function as a membrane-associated protein kinase that phosphorylates phoB in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=423, Percent_Identity=37.8250591016548, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=32.3275862068966, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786783, Length=255, Percent_Identity=29.0196078431373, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI145693157, Length=226, Percent_Identity=30.9734513274336, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790346, Length=209, Percent_Identity=29.6650717703349, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790861, Length=203, Percent_Identity=31.5270935960591, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI48994928, Length=276, Percent_Identity=28.2608695652174, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1789149, Length=229, Percent_Identity=28.3842794759825, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790551, Length=213, Percent_Identity=31.924882629108, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1789403, Length=202, Percent_Identity=34.1584158415842, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=25.764192139738, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=237, Percent_Identity=28.2700421940928, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=226, Percent_Identity=27.4336283185841, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=23.6514522821577, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=24.6636771300448, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=218, Percent_Identity=28.4403669724771, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR021766
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014310 [H]

Pfam domain/function: PF11808 DUF3329; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50514; Mature: 50383

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIVSTLHRIRFAWFKTLGVLALILFAALLVGLLIGQVWIVLTLTALAEIAWQYWRLHQV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYQLAVRRRWTRSMDIGVWKQLDHLIYRNQTDMRARVHRLMEMLRTYRAAAAALPDAVVV
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VDCNSQCIQWFNEAANTLLGLRYPSDLDRPVVERLQPLPLASWLTQGCNAESMLDVPSPV
EECCHHHHHHHHHHHHHHEECCCCCCCCHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC
NPDVRLNLHLIPYFDDYLLLVARDVSKLLRLEQVKRDFVANVSHELRTPLTVVHGYLDML
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHC
DPDDFPDAAPMLDEMRKQSQRMTQLVEDLLTLSRLESQEELEQEQVAMVPMLATLHREAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AHSQGRHTIEVVDNAGCDLFGSNKDLHSAFSNLITNAVRYTPAGGSVRVCFQREDDGVAL
HHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCEEE
MVCDTGYGIPTSHLPRITERFYRVSSSRSRERGGTGLGLSIVKHVLELHQARLDIISEVG
EEEECCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
KGSEFSCHFAAARVAMRESESVPIQP
CCCCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SIVSTLHRIRFAWFKTLGVLALILFAALLVGLLIGQVWIVLTLTALAEIAWQYWRLHQV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYQLAVRRRWTRSMDIGVWKQLDHLIYRNQTDMRARVHRLMEMLRTYRAAAAALPDAVVV
HHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
VDCNSQCIQWFNEAANTLLGLRYPSDLDRPVVERLQPLPLASWLTQGCNAESMLDVPSPV
EECCHHHHHHHHHHHHHHEECCCCCCCCHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCC
NPDVRLNLHLIPYFDDYLLLVARDVSKLLRLEQVKRDFVANVSHELRTPLTVVHGYLDML
CCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHC
DPDDFPDAAPMLDEMRKQSQRMTQLVEDLLTLSRLESQEELEQEQVAMVPMLATLHREAE
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
AHSQGRHTIEVVDNAGCDLFGSNKDLHSAFSNLITNAVRYTPAGGSVRVCFQREDDGVAL
HHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHEECCCCCCEEEEEEECCCCEEE
MVCDTGYGIPTSHLPRITERFYRVSSSRSRERGGTGLGLSIVKHVLELHQARLDIISEVG
EEEECCCCCCCHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHC
KGSEFSCHFAAARVAMRESESVPIQP
CCCCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043; 2115874 [H]