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The map label for this gene is rsmB

Identifier: 182682377

GI number: 182682377

Start: 2067262

End: 2068557

Strand: Reverse

Name: rsmB

Synonym: XfasM23_1863

Alternate gene names: 182682377

Gene position: 2068557-2067262 (Counterclockwise)

Preceding gene: 182682378

Following gene: 182682376

Centisome position: 81.58

GC content: 59.26

Gene sequence:

>1296_bases
GTGAGCGATGGCATTGCACCGCGTGTGGTTGCGGCGCGGGTGCTAGCTTTGGTCGTGGATCAGGGGCGTTCGCTCAAGAC
GGAGCTGGCCGCAGCGTTGCCAACGTTGGAGGATGTGCGTGACCGTGCCTTGGTCGAGGCAATCTGTTTTGCAGTGTTGC
GGCGGCGTCCGGTTTATGAGGCTGCGCTCACCCGGTGGTTGGCGCGTCCCTTGGGTCGTGGTGATGCGCAGTTGCGCGGC
TTGCTTATGGTTGGTTTTGCGCAACTTGATGTTTTAAAAGTACCGCCGTATGCGGCGTTGTCAGCGACGGTTGATGCCTG
CCGCGTGCTGGGGTGGCCCCACCGGGTCAGTTTTGTCAATGCGGTGTTGCGTCGTGCTCAGCGTGAACGTTTGCCGGTCG
TATCGTCTGATGCTGCTTGGCCACGTTGGTTGGCAGAGCGCATCCGTGCTGACTGGGGGGAGCAGGCAGAAGCAATTTTT
GATGCCAGCCTTAAGCCAGCGCCGATGTGGTTACGGGTCAATCTGCGCTATGGCGATCGTCACACCTATGTGCAGCGTTT
GCAGGCAGCAGGTTTGGAGGCTGTACCAAGTGGATTGGTCCCTGAGGCGCTTGCGTTGGATTGTTCTGTGCCTGTAGTGC
AATTGCCCGGGTTCCAGGGCGGTGAAGTGTCGGTTCAAGACTTGTCGGCGCAGCAAGTGGCTGCGTTGTTGTCACCAGCG
CCACACGCCCGTCTGCTTGATGCGTGTGCCGCGCCAGGCGGCAAAGCTGCACATCTGTTAGAGCGTGCGCCCACACTGTG
CTTGACTGCGTTGGATGTAGATATGCAGCGGTTGCGTCGGGTTGCTGAGACTTGTGACCGCATCCATGTCAAGGCTAGGT
TGTGTGTTGCCGATGCGACTGATCTTGCAGCGTGGTGGGATGGGGAGCCGTTTGATGCGGTGTTGTTGGATGCGCCCTGC
TCAGCGACTGGAGTGGTACGCCGCCAACCGGACGTACTGCTCCACCGGCGTGCCGAGGATCTATTGCCTTTATTAAATAT
TCAGTCCCGATTGCTGGATGCTTGTTGGCGCACCTTGCGCCCCGGAGGAGTACTGGTGTATGTGACCTGTTCGGTGCTGC
GTGCCGAGAACCAGACTCAGTTGGAAGCGTTTCTGGCCAGGACGGCCGATGCCTGCGCCGAGGACCCTGGGGATGCGTAT
GGTCAGCCCGCTGGTCTGGGGCGGCAGCGCTTGCCGGGTGAACAAGGCGGTGATGGCTTTTTTTATGCCAGGTTGATTAA
AGACATATCAATGTGA

Upstream 100 bases:

>100_bases
TGCAGGGCGCGTTGCGTTTGTGCAGATTACAGAGGGAAGGTGGGAAAGCGATCACCGTGGCTGATTACCTTAACGCCCGC
CGAGACTTGCAGGTCCGTGC

Downstream 100 bases:

>100_bases
AAAGACATATAAATGTGAAATGTATCAGTTCAAGTGACTATTACAGCTTCATGAAAATCCGGCACGTTTCACATCAAGCT
TGGTTGCTGTTTCTGGTGGC

Product: sun protein

Products: NA

Alternate protein names: 16S rRNA m5C967 methyltransferase; rRNA (cytosine-C(5)-)-methyltransferase rsmB

Number of amino acids: Translated: 431; Mature: 430

Protein sequence:

>431_residues
MSDGIAPRVVAARVLALVVDQGRSLKTELAAALPTLEDVRDRALVEAICFAVLRRRPVYEAALTRWLARPLGRGDAQLRG
LLMVGFAQLDVLKVPPYAALSATVDACRVLGWPHRVSFVNAVLRRAQRERLPVVSSDAAWPRWLAERIRADWGEQAEAIF
DASLKPAPMWLRVNLRYGDRHTYVQRLQAAGLEAVPSGLVPEALALDCSVPVVQLPGFQGGEVSVQDLSAQQVAALLSPA
PHARLLDACAAPGGKAAHLLERAPTLCLTALDVDMQRLRRVAETCDRIHVKARLCVADATDLAAWWDGEPFDAVLLDAPC
SATGVVRRQPDVLLHRRAEDLLPLLNIQSRLLDACWRTLRPGGVLVYVTCSVLRAENQTQLEAFLARTADACAEDPGDAY
GQPAGLGRQRLPGEQGGDGFFYARLIKDISM

Sequences:

>Translated_431_residues
MSDGIAPRVVAARVLALVVDQGRSLKTELAAALPTLEDVRDRALVEAICFAVLRRRPVYEAALTRWLARPLGRGDAQLRG
LLMVGFAQLDVLKVPPYAALSATVDACRVLGWPHRVSFVNAVLRRAQRERLPVVSSDAAWPRWLAERIRADWGEQAEAIF
DASLKPAPMWLRVNLRYGDRHTYVQRLQAAGLEAVPSGLVPEALALDCSVPVVQLPGFQGGEVSVQDLSAQQVAALLSPA
PHARLLDACAAPGGKAAHLLERAPTLCLTALDVDMQRLRRVAETCDRIHVKARLCVADATDLAAWWDGEPFDAVLLDAPC
SATGVVRRQPDVLLHRRAEDLLPLLNIQSRLLDACWRTLRPGGVLVYVTCSVLRAENQTQLEAFLARTADACAEDPGDAY
GQPAGLGRQRLPGEQGGDGFFYARLIKDISM
>Mature_430_residues
SDGIAPRVVAARVLALVVDQGRSLKTELAAALPTLEDVRDRALVEAICFAVLRRRPVYEAALTRWLARPLGRGDAQLRGL
LMVGFAQLDVLKVPPYAALSATVDACRVLGWPHRVSFVNAVLRRAQRERLPVVSSDAAWPRWLAERIRADWGEQAEAIFD
ASLKPAPMWLRVNLRYGDRHTYVQRLQAAGLEAVPSGLVPEALALDCSVPVVQLPGFQGGEVSVQDLSAQQVAALLSPAP
HARLLDACAAPGGKAAHLLERAPTLCLTALDVDMQRLRRVAETCDRIHVKARLCVADATDLAAWWDGEPFDAVLLDAPCS
ATGVVRRQPDVLLHRRAEDLLPLLNIQSRLLDACWRTLRPGGVLVYVTCSVLRAENQTQLEAFLARTADACAEDPGDAYG
QPAGLGRQRLPGEQGGDGFFYARLIKDISM

Specific function: Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family

Homologues:

Organism=Homo sapiens, GI76150625, Length=238, Percent_Identity=31.9327731092437, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI76150623, Length=238, Percent_Identity=31.9327731092437, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI32698918, Length=172, Percent_Identity=30.8139534883721, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI301336155, Length=279, Percent_Identity=27.2401433691756, Blast_Score=73, Evalue=6e-13,
Organism=Homo sapiens, GI11545785, Length=157, Percent_Identity=35.031847133758, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI39995082, Length=299, Percent_Identity=25.752508361204, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI2367212, Length=428, Percent_Identity=41.3551401869159, Blast_Score=314, Evalue=8e-87,
Organism=Escherichia coli, GI87081985, Length=225, Percent_Identity=31.5555555555556, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17536757, Length=240, Percent_Identity=30, Blast_Score=95, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI25143471, Length=190, Percent_Identity=32.1052631578947, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6324268, Length=311, Percent_Identity=27.9742765273312, Blast_Score=103, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6319447, Length=179, Percent_Identity=29.0502793296089, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI22024126, Length=184, Percent_Identity=34.2391304347826, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355201, Length=209, Percent_Identity=29.1866028708134, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920494, Length=205, Percent_Identity=29.7560975609756, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21356513, Length=167, Percent_Identity=31.7365269461078, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24668781, Length=167, Percent_Identity=31.7365269461078, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMB_XYLFT (Q87AR1)

Other databases:

- EMBL:   AE009442
- RefSeq:   NP_779946.1
- ProteinModelPortal:   Q87AR1
- SMR:   Q87AR1
- STRING:   Q87AR1
- GeneID:   1143103
- GenomeReviews:   AE009442_GR
- KEGG:   xft:PD1761
- eggNOG:   COG0144
- HOGENOM:   HBG726909
- OMA:   ANNAHPP
- ProtClustDB:   PRK10901
- BioCyc:   XFAS183190:PD_1761-MONOMER
- GO:   GO:0005737
- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573
- Gene3D:   G3DSA:1.10.940.10
- TIGRFAMs:   TIGR00563

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB; SSF48013 NusB_RsmB_TIM44

EC number: =2.1.1.176

Molecular weight: Translated: 46933; Mature: 46802

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: ACT_SITE 370-370 BINDING 272-272 BINDING 298-298 BINDING 317-317

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGIAPRVVAARVLALVVDQGRSLKTELAAALPTLEDVRDRALVEAICFAVLRRRPVYE
CCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHH
AALTRWLARPLGRGDAQLRGLLMVGFAQLDVLKVPPYAALSATVDACRVLGWPHRVSFVN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCCHHHHHHH
AVLRRAQRERLPVVSSDAAWPRWLAERIRADWGEQAEAIFDASLKPAPMWLRVNLRYGDR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEEEEECCH
HTYVQRLQAAGLEAVPSGLVPEALALDCSVPVVQLPGFQGGEVSVQDLSAQQVAALLSPA
HHHHHHHHHCCCHHCCCCCCCHHHEECCCCCEEECCCCCCCCEEHHHHHHHHHHHHHCCC
PHARLLDACAAPGGKAAHLLERAPTLCLTALDVDMQRLRRVAETCDRIHVKARLCVADAT
CHHHHHHHHCCCCCHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCH
DLAAWWDGEPFDAVLLDAPCSATGVVRRQPDVLLHRRAEDLLPLLNIQSRLLDACWRTLR
HHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGVLVYVTCSVLRAENQTQLEAFLARTADACAEDPGDAYGQPAGLGRQRLPGEQGGDGF
CCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCHH
FYARLIKDISM
HHHHHHHHHCC
>Mature Secondary Structure 
SDGIAPRVVAARVLALVVDQGRSLKTELAAALPTLEDVRDRALVEAICFAVLRRRPVYE
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHH
AALTRWLARPLGRGDAQLRGLLMVGFAQLDVLKVPPYAALSATVDACRVLGWPHRVSFVN
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHHHCCCHHHHHHH
AVLRRAQRERLPVVSSDAAWPRWLAERIRADWGEQAEAIFDASLKPAPMWLRVNLRYGDR
HHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEEEEECCH
HTYVQRLQAAGLEAVPSGLVPEALALDCSVPVVQLPGFQGGEVSVQDLSAQQVAALLSPA
HHHHHHHHHCCCHHCCCCCCCHHHEECCCCCEEECCCCCCCCEEHHHHHHHHHHHHHCCC
PHARLLDACAAPGGKAAHLLERAPTLCLTALDVDMQRLRRVAETCDRIHVKARLCVADAT
CHHHHHHHHCCCCCHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCH
DLAAWWDGEPFDAVLLDAPCSATGVVRRQPDVLLHRRAEDLLPLLNIQSRLLDACWRTLR
HHHHCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PGGVLVYVTCSVLRAENQTQLEAFLARTADACAEDPGDAYGQPAGLGRQRLPGEQGGDGF
CCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCCCCHH
FYARLIKDISM
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12533478