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The map label for this gene is yghZ [H]

Identifier: 182682308

GI number: 182682308

Start: 1990178

End: 1991143

Strand: Reverse

Name: yghZ [H]

Synonym: XfasM23_1791

Alternate gene names: 182682308

Gene position: 1991143-1990178 (Counterclockwise)

Preceding gene: 182682310

Following gene: 182682306

Centisome position: 78.52

GC content: 53.21

Gene sequence:

>966_bases
ATGCATTATCGTCGTCTTGGTTCTACTGGGTTGCAGTTATCAGTCCTTTCTTTCGGTACTTGGGTGACTTTTGGCAATCA
GGTTGCGCGCGATGAGGCTCGTAATTTAGTGGCTTGTGCTTGGGATCACGGCGTGAATTTCTTTGATGGTGCTGAGACCT
ATGCTCAAGGGCGTGCGGAGCAGGTGTTGGGGGATGTGATTGCCGACTTGCGTTTGCCACGTGATGGTTATTGTGTATCC
AGTAAGGTGTTCTTTGGGGCTGTGAATGAGCCACGTCCGACGCAGTGCGGGCTTTCACGCAAGCATGTCCATGATGCTTG
CCATGCTGCATTGAAGCGTTTGCGAGTGGACTATTTGGACCTTTTTTTCTGTCATCGTCCTGATGCTGATACTCCGATTG
AGGAGACGGTACGTGCGATGACTACGCTGATTCGGCAGGGCAAGGTGCTTTACTGGGGCACTTCGGAGTGGTCAGCTGCA
CAGATTGCCGAAGCAATTGCAATTGCCTCGCGTGAGCATCTTGAGCGTCCGTGGGTAGAGCAGCCTCAGTACAACTTGCT
ACACCGTGAGCGTGTAGAGCGGGAGTATGTATCGCTCTATGCTCAGGGTTTGGGCACGACGATCTGGTCGCCTTTGGCAT
CGGGGTTGCTGACTGGAAAACACAATGTGGGTGTGGCATCGGGCAGCCGTTTGGTGCAGCCAGGTTACGAGTGGTTACAG
AGGCAGGTGTTGGGTGAGGGTGAGGCGCGTTTGGTACAAGCGCGGCGCTTTAGTGAGGTTGCTGCTGATCTTGGCCAGTT
GCCGACGCAATTGGCGATTGCTTGGTGTTTACGTAATCCACATGTCTCTACGGTGATTCTCGGTGCGAGTCGGGTTGCTC
AATTGAAAGAAAATCTTCAGGCATTGCAGGTGGTTGCAGCGTTGGATGCTGCTGCTTGGCGATGTGTTGAGGCTGCAATG
GAATGA

Upstream 100 bases:

>100_bases
GACGATATCTACTTATTAGTAGTGCTGTGTGTTGTTGTTTTCTTTTGTTGTTGCATGGGTTGTTTCTTTATTCTCGCGTC
CTTTTAGGGAGTGGAGTTTT

Downstream 100 bases:

>100_bases
GTGATCCGAACCTGATGGAGTTGTGGTGCATGTCGGTATTGGGAGGTTGACTGTGTATTCCTTGGTTGGGATGTTTCATT
CATATCGGTATTGCTGAAGT

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 321; Mature: 321

Protein sequence:

>321_residues
MHYRRLGSTGLQLSVLSFGTWVTFGNQVARDEARNLVACAWDHGVNFFDGAETYAQGRAEQVLGDVIADLRLPRDGYCVS
SKVFFGAVNEPRPTQCGLSRKHVHDACHAALKRLRVDYLDLFFCHRPDADTPIEETVRAMTTLIRQGKVLYWGTSEWSAA
QIAEAIAIASREHLERPWVEQPQYNLLHRERVEREYVSLYAQGLGTTIWSPLASGLLTGKHNVGVASGSRLVQPGYEWLQ
RQVLGEGEARLVQARRFSEVAADLGQLPTQLAIAWCLRNPHVSTVILGASRVAQLKENLQALQVVAALDAAAWRCVEAAM
E

Sequences:

>Translated_321_residues
MHYRRLGSTGLQLSVLSFGTWVTFGNQVARDEARNLVACAWDHGVNFFDGAETYAQGRAEQVLGDVIADLRLPRDGYCVS
SKVFFGAVNEPRPTQCGLSRKHVHDACHAALKRLRVDYLDLFFCHRPDADTPIEETVRAMTTLIRQGKVLYWGTSEWSAA
QIAEAIAIASREHLERPWVEQPQYNLLHRERVEREYVSLYAQGLGTTIWSPLASGLLTGKHNVGVASGSRLVQPGYEWLQ
RQVLGEGEARLVQARRFSEVAADLGQLPTQLAIAWCLRNPHVSTVILGASRVAQLKENLQALQVVAALDAAAWRCVEAAM
E
>Mature_321_residues
MHYRRLGSTGLQLSVLSFGTWVTFGNQVARDEARNLVACAWDHGVNFFDGAETYAQGRAEQVLGDVIADLRLPRDGYCVS
SKVFFGAVNEPRPTQCGLSRKHVHDACHAALKRLRVDYLDLFFCHRPDADTPIEETVRAMTTLIRQGKVLYWGTSEWSAA
QIAEAIAIASREHLERPWVEQPQYNLLHRERVEREYVSLYAQGLGTTIWSPLASGLLTGKHNVGVASGSRLVQPGYEWLQ
RQVLGEGEARLVQARRFSEVAADLGQLPTQLAIAWCLRNPHVSTVILGASRVAQLKENLQALQVVAALDAAAWRCVEAAM
E

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=45.5414012738853, Blast_Score=282, Evalue=2e-76,
Organism=Homo sapiens, GI4504825, Length=312, Percent_Identity=45.5128205128205, Blast_Score=280, Evalue=9e-76,
Organism=Homo sapiens, GI27436964, Length=312, Percent_Identity=43.5897435897436, Blast_Score=270, Evalue=1e-72,
Organism=Homo sapiens, GI27436962, Length=312, Percent_Identity=43.5897435897436, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI27436966, Length=312, Percent_Identity=43.2692307692308, Blast_Score=268, Evalue=7e-72,
Organism=Homo sapiens, GI27436971, Length=310, Percent_Identity=44.1935483870968, Blast_Score=262, Evalue=3e-70,
Organism=Homo sapiens, GI41152114, Length=279, Percent_Identity=29.0322580645161, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI223718702, Length=275, Percent_Identity=29.0909090909091, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI41327764, Length=221, Percent_Identity=29.8642533936652, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789375, Length=315, Percent_Identity=35.8730158730159, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI87081735, Length=315, Percent_Identity=33.6507936507937, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1789199, Length=341, Percent_Identity=30.4985337243402, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1788070, Length=340, Percent_Identity=27.6470588235294, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI1788081, Length=157, Percent_Identity=34.3949044585987, Blast_Score=75, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6325169, Length=324, Percent_Identity=28.7037037037037, Blast_Score=113, Evalue=5e-26,
Organism=Saccharomyces cerevisiae, GI6323998, Length=316, Percent_Identity=24.0506329113924, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=288, Percent_Identity=23.2638888888889, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319951, Length=300, Percent_Identity=23.3333333333333, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322615, Length=225, Percent_Identity=24.4444444444444, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640980, Length=345, Percent_Identity=30.4347826086957, Blast_Score=174, Evalue=9e-44,
Organism=Drosophila melanogaster, GI45549126, Length=345, Percent_Identity=30.4347826086957, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24646155, Length=312, Percent_Identity=28.8461538461538, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24646159, Length=172, Percent_Identity=28.4883720930233, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 35689; Mature: 35689

Theoretical pI: Translated: 7.28; Mature: 7.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYRRLGSTGLQLSVLSFGTWVTFGNQVARDEARNLVACAWDHGVNFFDGAETYAQGRAE
CCCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHCCHHH
QVLGDVIADLRLPRDGYCVSSKVFFGAVNEPRPTQCGLSRKHVHDACHAALKRLRVDYLD
HHHHHHHHHHCCCCCCCEEECEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFFCHRPDADTPIEETVRAMTTLIRQGKVLYWGTSEWSAAQIAEAIAIASREHLERPWVE
HHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
QPQYNLLHRERVEREYVSLYAQGLGTTIWSPLASGLLTGKHNVGVASGSRLVQPGYEWLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
RQVLGEGEARLVQARRFSEVAADLGQLPTQLAIAWCLRNPHVSTVILGASRVAQLKENLQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
ALQVVAALDAAAWRCVEAAME
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHYRRLGSTGLQLSVLSFGTWVTFGNQVARDEARNLVACAWDHGVNFFDGAETYAQGRAE
CCCCCCCCCCCEEEHHHHHHHHHHCHHHHHHHHCCEEEEEECCCCCCCCCHHHHHCCHHH
QVLGDVIADLRLPRDGYCVSSKVFFGAVNEPRPTQCGLSRKHVHDACHAALKRLRVDYLD
HHHHHHHHHHCCCCCCCEEECEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
LFFCHRPDADTPIEETVRAMTTLIRQGKVLYWGTSEWSAAQIAEAIAIASREHLERPWVE
HHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCC
QPQYNLLHRERVEREYVSLYAQGLGTTIWSPLASGLLTGKHNVGVASGSRLVQPGYEWLQ
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
RQVLGEGEARLVQARRFSEVAADLGQLPTQLAIAWCLRNPHVSTVILGASRVAQLKENLQ
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHH
ALQVVAALDAAAWRCVEAAME
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]