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The map label for this gene is hda [H]

Identifier: 182682168

GI number: 182682168

Start: 1825701

End: 1826402

Strand: Reverse

Name: hda [H]

Synonym: XfasM23_1647

Alternate gene names: 182682168

Gene position: 1826402-1825701 (Counterclockwise)

Preceding gene: 182682169

Following gene: 182682165

Centisome position: 72.03

GC content: 56.41

Gene sequence:

>702_bases
GTGAGTGTTTCGCAGCTTCCGCTGGCCTTGCGTTATTCTTCAGATCAGCGTTTTGAAACCTATCTGCACGCTCCCTCTGG
TTTGATTGCGCAACTGCGTGCTCTGGTCGATCAGTGCTCACGGGAGTGGATCTATCTTGTGGGTGCTTCCGGGAGTGGTA
AGACGCATTTGGCATTGGCGTTGTGTGCGGCTGCCGAGCAGGTCGGGCAGTCAGTGGCTTACTTGCCGCTACAGGTTGCC
GTAGGGCGCTTACGCGATGCGTTGGAAGCGCTGGAAGGCTGTGTCTTGGTCGTGTTGGATGGTTTGCAGGCGATCGTTGG
GATGCGTGAGGACGAGATTGCGTTATTCGACTTTCATAATCGCGCGCGTGCGGCTGGTATTACGTTGTTGTATACGGCCC
GCGCTATCCCTGATGGGCTTGGGTTGACGTTGCCGGATTTGCGTTCACGTGTGGCGCAGTGCATCCGTATTGCGTTGCCT
ACGCTGGATGATGTCGGCCGTGCATCCGTGTTGCGTGAACGTGCGCAACGTCGCGGGCTGATGTTGGATGAGGCTGCAAT
TGAGTGGCTGTTGAGTCGTGGTGATCGTGATTTAGGCAGTTTGGTGATGTTGCTGGAAAGGCTTGATCGTGAATCGCTAG
CCACAAAGCGGCGCGTCACCATTCCGTTCTTGCGTCATGTGCTTGCCGAGGGTGGGGGTTGA

Upstream 100 bases:

>100_bases
AGCGTTATATCGAAAGTGAGTTTTATAAAGGTCAGTATTTGGCGGTCGCGTTGCATGAGTGTAAAAGCGATGAGAACTGT
GATGGCAAAAAGGACGCGGT

Downstream 100 bases:

>100_bases
GGTGCTTTGCTGTTGGGAGGTAGGGTCTTCTGAATCCAACTAATGAAGCCAGTGTCAGGGATTCATGTTGTGATTAAAGC
GCTAACACGTTGTGAGTGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MSVSQLPLALRYSSDQRFETYLHAPSGLIAQLRALVDQCSREWIYLVGASGSGKTHLALALCAAAEQVGQSVAYLPLQVA
VGRLRDALEALEGCVLVVLDGLQAIVGMREDEIALFDFHNRARAAGITLLYTARAIPDGLGLTLPDLRSRVAQCIRIALP
TLDDVGRASVLRERAQRRGLMLDEAAIEWLLSRGDRDLGSLVMLLERLDRESLATKRRVTIPFLRHVLAEGGG

Sequences:

>Translated_233_residues
MSVSQLPLALRYSSDQRFETYLHAPSGLIAQLRALVDQCSREWIYLVGASGSGKTHLALALCAAAEQVGQSVAYLPLQVA
VGRLRDALEALEGCVLVVLDGLQAIVGMREDEIALFDFHNRARAAGITLLYTARAIPDGLGLTLPDLRSRVAQCIRIALP
TLDDVGRASVLRERAQRRGLMLDEAAIEWLLSRGDRDLGSLVMLLERLDRESLATKRRVTIPFLRHVLAEGGG
>Mature_232_residues
SVSQLPLALRYSSDQRFETYLHAPSGLIAQLRALVDQCSREWIYLVGASGSGKTHLALALCAAAEQVGQSVAYLPLQVAV
GRLRDALEALEGCVLVVLDGLQAIVGMREDEIALFDFHNRARAAGITLLYTARAIPDGLGLTLPDLRSRVAQCIRIALPT
LDDVGRASVLRERAQRRGLMLDEAAIEWLLSRGDRDLGSLVMLLERLDRESLATKRRVTIPFLRHVLAEGGG

Specific function: Mediates the interactions of dnaA with the beta subunit sliding clamp, promoting hydrolysis of dnaA-bound ATP. It is essential for the control of initiation of DNA replication by inhibiting reinitiation of replication [H]

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family. HdA subfamily [H]

Homologues:

Organism=Escherichia coli, GI226510964, Length=229, Percent_Identity=35.8078602620087, Blast_Score=126, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020591
- InterPro:   IPR017788
- InterPro:   IPR013317
- InterPro:   IPR022864 [H]

Pfam domain/function: PF00308 Bac_DnaA [H]

EC number: NA

Molecular weight: Translated: 25437; Mature: 25306

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSQLPLALRYSSDQRFETYLHAPSGLIAQLRALVDQCSREWIYLVGASGSGKTHLALA
CCCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
LCAAAEQVGQSVAYLPLQVAVGRLRDALEALEGCVLVVLDGLQAIVGMREDEIALFDFHN
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
RARAAGITLLYTARAIPDGLGLTLPDLRSRVAQCIRIALPTLDDVGRASVLRERAQRRGL
HHHHHCCHHEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
MLDEAAIEWLLSRGDRDLGSLVMLLERLDRESLATKRRVTIPFLRHVLAEGGG
CHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SVSQLPLALRYSSDQRFETYLHAPSGLIAQLRALVDQCSREWIYLVGASGSGKTHLALA
CCCCCCEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHH
LCAAAEQVGQSVAYLPLQVAVGRLRDALEALEGCVLVVLDGLQAIVGMREDEIALFDFHN
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCC
RARAAGITLLYTARAIPDGLGLTLPDLRSRVAQCIRIALPTLDDVGRASVLRERAQRRGL
HHHHHCCHHEEEHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCC
MLDEAAIEWLLSRGDRDLGSLVMLLERLDRESLATKRRVTIPFLRHVLAEGGG
CHHHHHHHHHHHCCCCCHHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA