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The map label for this gene is mip [H]

Identifier: 182682134

GI number: 182682134

Start: 1786850

End: 1787548

Strand: Direct

Name: mip [H]

Synonym: XfasM23_1612

Alternate gene names: 182682134

Gene position: 1786850-1787548 (Clockwise)

Preceding gene: 182682131

Following gene: 182682135

Centisome position: 70.47

GC content: 51.79

Gene sequence:

>699_bases
ATGAAGTTGCGTCTGATCGCAGTCGCTGTTGCGACCCTGGCCCTGACCGGCAATGCATTCGCCCAGGACATCACGTCCGA
AAAGGGAAAAATAAGCTATTACTTGGGCTATCAGCAAGGCAGCGCTTTAGCCGAGCTGACTGGGCGCGGGGAGCAGTTGG
ATATGAACTCTGTGATCAAAGGTATGGAGGACGCCTACAGCAAGAAGCAACCAGGCGTTACTGTTGAGCAGTTACGTCCA
GCGATTGAAGCATTCCAAAAACGCGAACAAGCCCGCGCACAGCAAGCGAAGGCCGAATACGATAAAGCAGCTGCTGAAAA
CAAGGTCAAGAGTGAACAATTCATGGCCAAAAATAAGAGCGCCACAGGTGTAAAATCCCTTCCTAATGGCGTGCAGTACA
AGATCATAGAAGTTGGCAAGGGTGCCAAGCCGACCCAGGCCAGTACCGTTCAGTTAGAAGTCGCTGGCCCATTCCCATGG
GGTCAACGTCCACAACAGGGACACCAAGCACAGCAAATCCCAGGGATTAAGGTCAGCGCGATTGACATTAAAGGCATGCG
CGAAGCCCTAATAAATATGCCAGCCGGTTCAAAGTGGGAAATCACCCTACCAGCTGACGCTTACGGCGCCGATCCACGTA
ATATTCTCCCACCAAACGCGGCTGTTCAATTTGAAGTCAAACTGCTGAGCGTCAAGTAA

Upstream 100 bases:

>100_bases
GAACTTGTATGAACTATTTTCTGTCTTAGCGTGACACTTGCAAGTGGCGGAACGAAATATCGCCCGCTATCCTATATCAT
CATTATCTGGAGAATTTTTG

Downstream 100 bases:

>100_bases
GGTAGCACCCATATACGTATGACGACGCCGGTTCTATCACAGCGCAGGCGTCGTCTTATGTATGTCCACACTTTGTAAAT
GGCGATATCTTGATCTGCGT

Product: FKBP-type peptidyl-prolyl isomerase domain-containing protein

Products: NA

Alternate protein names: Macrophage infectivity potentiator; Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MKLRLIAVAVATLALTGNAFAQDITSEKGKISYYLGYQQGSALAELTGRGEQLDMNSVIKGMEDAYSKKQPGVTVEQLRP
AIEAFQKREQARAQQAKAEYDKAAAENKVKSEQFMAKNKSATGVKSLPNGVQYKIIEVGKGAKPTQASTVQLEVAGPFPW
GQRPQQGHQAQQIPGIKVSAIDIKGMREALINMPAGSKWEITLPADAYGADPRNILPPNAAVQFEVKLLSVK

Sequences:

>Translated_232_residues
MKLRLIAVAVATLALTGNAFAQDITSEKGKISYYLGYQQGSALAELTGRGEQLDMNSVIKGMEDAYSKKQPGVTVEQLRP
AIEAFQKREQARAQQAKAEYDKAAAENKVKSEQFMAKNKSATGVKSLPNGVQYKIIEVGKGAKPTQASTVQLEVAGPFPW
GQRPQQGHQAQQIPGIKVSAIDIKGMREALINMPAGSKWEITLPADAYGADPRNILPPNAAVQFEVKLLSVK
>Mature_232_residues
MKLRLIAVAVATLALTGNAFAQDITSEKGKISYYLGYQQGSALAELTGRGEQLDMNSVIKGMEDAYSKKQPGVTVEQLRP
AIEAFQKREQARAQQAKAEYDKAAAENKVKSEQFMAKNKSATGVKSLPNGVQYKIIEVGKGAKPTQASTVQLEVAGPFPW
GQRPQQGHQAQQIPGIKVSAIDIKGMREALINMPAGSKWEITLPADAYGADPRNILPPNAAVQFEVKLLSVK

Specific function: Essential virulence factor associated with macrophage infectivity. Exhibits PPIase activity [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789745, Length=215, Percent_Identity=28.3720930232558, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI87082390, Length=202, Percent_Identity=31.1881188118812, Blast_Score=77, Evalue=8e-16,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008104
- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 25066; Mature: 25066

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLRLIAVAVATLALTGNAFAQDITSEKGKISYYLGYQQGSALAELTGRGEQLDMNSVIK
CCEEHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCEECHHHHHH
GMEDAYSKKQPGVTVEQLRPAIEAFQKREQARAQQAKAEYDKAAAENKVKSEQFMAKNKS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ATGVKSLPNGVQYKIIEVGKGAKPTQASTVQLEVAGPFPWGQRPQQGHQAQQIPGIKVSA
CCCHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCCEEEE
IDIKGMREALINMPAGSKWEITLPADAYGADPRNILPPNAAVQFEVKLLSVK
EEHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECC
>Mature Secondary Structure
MKLRLIAVAVATLALTGNAFAQDITSEKGKISYYLGYQQGSALAELTGRGEQLDMNSVIK
CCEEHHHHHHHHHHHCCCHHHHHHCCCCCCEEEEEECCCCCHHHHHCCCCCEECHHHHHH
GMEDAYSKKQPGVTVEQLRPAIEAFQKREQARAQQAKAEYDKAAAENKVKSEQFMAKNKS
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ATGVKSLPNGVQYKIIEVGKGAKPTQASTVQLEVAGPFPWGQRPQQGHQAQQIPGIKVSA
CCCHHHCCCCCEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHCCCCEEEE
IDIKGMREALINMPAGSKWEITLPADAYGADPRNILPPNAAVQFEVKLLSVK
EEHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA