Click here to switch to the map view.

The map label for this gene is metX

Identifier: 182682091

GI number: 182682091

Start: 1741319

End: 1742431

Strand: Direct

Name: metX

Synonym: XfasM23_1569

Alternate gene names: 182682091

Gene position: 1741319-1742431 (Clockwise)

Preceding gene: 182682090

Following gene: 182682099

Centisome position: 68.67

GC content: 56.42

Gene sequence:

>1113_bases
ATGACCGAATTTATCCCTCCGGGCAGCCTATTCCATGCGCTCTCCTCTCCATTTGCGATGAAGCGTGGCGGACAACTCCA
CCACGCCCGCATCGCTTACGAAACATGGGGCCGCCTCAATGCCGGCGCCACCAATGCCATTCTGATCATGCCTGGCTTAT
CACCCAATGCACATGCCGCACACCATGACAGCAATGCTGAGCCAGGCTGGTGGGAGTCAATGCTAGGTCCAGGCAAACCC
ATCGACACAGACCGTTGGTTCGTGATCTGTGTCAACTCACTTGGTAGCTGCAAAGGATCGACTGGCCCTGCATCGTACAA
CCCCATCACGCAGGCCATGTATCGTTTGGACTTTCCAGCACTGTCAATCGAAGACGGGGCCAATGCCGCAATTGAAGTGG
TACATGCACTGGGCATCAAGCAACTTGCCAGCCTGATCGGCAATTCAATGGGGGGCATGACGGCACTGGCCATCCTGCTG
TTACATCCAGATATTGCCCGCAGCCACATCAACATCTCAGGCAGCGCGCAGGCATTACCGTTTTCCATCGCCATTCGCTC
GCTACAACGCGAGGCGATCCGCCTGGACCCCCATTGGAAGCAGGGACACTACGACGACACCCACTACCCGGAATCGGGGC
TACGCATCGCACGCAAACTCGGGGTGATCACCTACCGCTCCGCGCTGGAATGGGACGGGCGTTTTGGCCGGGTACGCTTG
GATTCGGACCAAACCAACGACACACCATTCGGACTGGAATTCCAAATTGAAAACTACTTGGAAAGCCATGCGCACCGCTT
CGTGCACACCTTCGACCCAAACTGCTACCTGTACCTGAGCCGCTCCATGGACTGGTTCGACGTGGCCGAGTACGCCAATG
GAGACATTATTGCCGGACTGGCCAGGATCCGAATCCAACGCGCACTCGCCATCGGTAGCCATACCGACATCCTCTTTCCA
ATACAACAGCAACAACAAATTGCCGAAGGGCTACGCCGTGGCGGTACACACGCCACCTTCCTGGGCCTTGACTCACCGCA
GGGACATGATGCATTCCTTGTAGATATCGCAGGATTTGGCCCTCCAGTGAAGGAATTTCTGGACGAACTGTGA

Upstream 100 bases:

>100_bases
CAACAGCGACGCGCGCCACAACCACATCTGCCAGGTTCCCCCACGTCGTGCCAAACACGGATCGCTCAATCCTAAGCACA
GACCTCACTAGAATTTTGAA

Downstream 100 bases:

>100_bases
GCCCCCCGGAACCGTAAGACGCCTGCGCAGATGTACACAGACAGGCTCATCAGCACCAAGCAACCCGCATCCCCGCAAGC
GCAACGATGCATTGATCCAC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTEFIPPGSLFHALSSPFAMKRGGQLHHARIAYETWGRLNAGATNAILIMPGLSPNAHAAHHDSNAEPGWWESMLGPGKP
IDTDRWFVICVNSLGSCKGSTGPASYNPITQAMYRLDFPALSIEDGANAAIEVVHALGIKQLASLIGNSMGGMTALAILL
LHPDIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWKQGHYDDTHYPESGLRIARKLGVITYRSALEWDGRFGRVRL
DSDQTNDTPFGLEFQIENYLESHAHRFVHTFDPNCYLYLSRSMDWFDVAEYANGDIIAGLARIRIQRALAIGSHTDILFP
IQQQQQIAEGLRRGGTHATFLGLDSPQGHDAFLVDIAGFGPPVKEFLDEL

Sequences:

>Translated_370_residues
MTEFIPPGSLFHALSSPFAMKRGGQLHHARIAYETWGRLNAGATNAILIMPGLSPNAHAAHHDSNAEPGWWESMLGPGKP
IDTDRWFVICVNSLGSCKGSTGPASYNPITQAMYRLDFPALSIEDGANAAIEVVHALGIKQLASLIGNSMGGMTALAILL
LHPDIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWKQGHYDDTHYPESGLRIARKLGVITYRSALEWDGRFGRVRL
DSDQTNDTPFGLEFQIENYLESHAHRFVHTFDPNCYLYLSRSMDWFDVAEYANGDIIAGLARIRIQRALAIGSHTDILFP
IQQQQQIAEGLRRGGTHATFLGLDSPQGHDAFLVDIAGFGPPVKEFLDEL
>Mature_369_residues
TEFIPPGSLFHALSSPFAMKRGGQLHHARIAYETWGRLNAGATNAILIMPGLSPNAHAAHHDSNAEPGWWESMLGPGKPI
DTDRWFVICVNSLGSCKGSTGPASYNPITQAMYRLDFPALSIEDGANAAIEVVHALGIKQLASLIGNSMGGMTALAILLL
HPDIARSHINISGSAQALPFSIAIRSLQREAIRLDPHWKQGHYDDTHYPESGLRIARKLGVITYRSALEWDGRFGRVRLD
SDQTNDTPFGLEFQIENYLESHAHRFVHTFDPNCYLYLSRSMDWFDVAEYANGDIIAGLARIRIQRALAIGSHTDILFPI
QQQQQIAEGLRRGGTHATFLGLDSPQGHDAFLVDIAGFGPPVKEFLDEL

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=221, Percent_Identity=31.6742081447964, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_XYLF2 (B2I700)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830251.1
- ProteinModelPortal:   B2I700
- SMR:   B2I700
- GeneID:   6202548
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1569
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- ProtClustDB:   PRK00175
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 40725; Mature: 40593

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: ACT_SITE 149-149 ACT_SITE 349-349

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFIPPGSLFHALSSPFAMKRGGQLHHARIAYETWGRLNAGATNAILIMPGLSPNAHAA
CCCCCCCHHHHHHHCCCHHHHCCCCEEEEEEEHHHCCCCCCCCCCEEEEECCCCCCCCCC
HHDSNAEPGWWESMLGPGKPIDTDRWFVICVNSLGSCKGSTGPASYNPITQAMYRLDFPA
CCCCCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCC
LSIEDGANAAIEVVHALGIKQLASLIGNSMGGMTALAILLLHPDIARSHINISGSAQALP
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHEECCCCCCCCCH
FSIAIRSLQREAIRLDPHWKQGHYDDTHYPESGLRIARKLGVITYRSALEWDGRFGRVRL
HHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHHHCCCCCCCEEEE
DSDQTNDTPFGLEFQIENYLESHAHRFVHTFDPNCYLYLSRSMDWFDVAEYANGDIIAGL
CCCCCCCCCCEEEEEHHHHHHHHHHHEEEEECCCEEEEEECCCCHHHHHHHCCCCHHHHH
ARIRIQRALAIGSHTDILFPIQQQQQIAEGLRRGGTHATFLGLDSPQGHDAFLVDIAGFG
HHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCC
PPVKEFLDEL
CHHHHHHHCC
>Mature Secondary Structure 
TEFIPPGSLFHALSSPFAMKRGGQLHHARIAYETWGRLNAGATNAILIMPGLSPNAHAA
CCCCCCHHHHHHHCCCHHHHCCCCEEEEEEEHHHCCCCCCCCCCEEEEECCCCCCCCCC
HHDSNAEPGWWESMLGPGKPIDTDRWFVICVNSLGSCKGSTGPASYNPITQAMYRLDFPA
CCCCCCCCCHHHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCC
LSIEDGANAAIEVVHALGIKQLASLIGNSMGGMTALAILLLHPDIARSHINISGSAQALP
EEECCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHEECCCCCCCCCH
FSIAIRSLQREAIRLDPHWKQGHYDDTHYPESGLRIARKLGVITYRSALEWDGRFGRVRL
HHHHHHHHHHHHEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEHHHHCCCCCCCEEEE
DSDQTNDTPFGLEFQIENYLESHAHRFVHTFDPNCYLYLSRSMDWFDVAEYANGDIIAGL
CCCCCCCCCCEEEEEHHHHHHHHHHHEEEEECCCEEEEEECCCCHHHHHHHCCCCHHHHH
ARIRIQRALAIGSHTDILFPIQQQQQIAEGLRRGGTHATFLGLDSPQGHDAFLVDIAGFG
HHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCC
PPVKEFLDEL
CHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA