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The map label for this gene is gpo [H]

Identifier: 182681502

GI number: 182681502

Start: 1121337

End: 1121843

Strand: Direct

Name: gpo [H]

Synonym: XfasM23_0956

Alternate gene names: 182681502

Gene position: 1121337-1121843 (Clockwise)

Preceding gene: 182681500

Following gene: 182681505

Centisome position: 44.22

GC content: 51.28

Gene sequence:

>507_bases
ATGAGCAGTATCTACACATTCACTTTCACACGTCTTGACGGACGGCCTCAAGCATTAGCAGATTGGCGTGGACAAGTACT
GTTATTGGTCAACGTGGCATCGCGTTGCGGCTTTACTCCACAATATGCTGGGTTGGAGATGCTATGGCAACGTTACCGCG
ATGCAGGTTTGATTGTTATTGGCTTTCCATGCGATCAATTCGCTGGGCAGGAACCTGGGGATGAGGCCAAAATCGCTGAG
TTTTGCACGCTGACCTATGGGGTGGATTTCCCAATGGCGGCGAAGATCAAAGTCAATGGAGCAGATGCACATCCACTTTG
GCAATGGTTGAAGCACCGCCGCCGTGGTTTGTTCGGTGTGGCCGCGATTAAGTGGAACTTCACTAAATTTCTGATCGGAC
GCAACGGGCAACCCATTGCCCGTTATTCGCCAATCAAGTCACCGGAGCAATTGGAGGTGCATATCGTTCGTGCCTTAGGG
GAGGAAGGGGGAGGGAATACTCATTGA

Upstream 100 bases:

>100_bases
GGCGGTTGTTAGAGTTCAGAATAACTCAACCAGGATGCACACACATGTAAGCCATACTTTTGCTAGCAAACTGTCACTTC
TATCGTGAGATAGGTTTCCT

Downstream 100 bases:

>100_bases
TCAACGAAAGCACGTTCAAATACGTAATCGCCGGGGCTACCTATACGTACTGAGGCATTGAAGCTACGTGCGTTCAATAA
GGTGCGTAGATCAGCCAGCA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MSSIYTFTFTRLDGRPQALADWRGQVLLLVNVASRCGFTPQYAGLEMLWQRYRDAGLIVIGFPCDQFAGQEPGDEAKIAE
FCTLTYGVDFPMAAKIKVNGADAHPLWQWLKHRRRGLFGVAAIKWNFTKFLIGRNGQPIARYSPIKSPEQLEVHIVRALG
EEGGGNTH

Sequences:

>Translated_168_residues
MSSIYTFTFTRLDGRPQALADWRGQVLLLVNVASRCGFTPQYAGLEMLWQRYRDAGLIVIGFPCDQFAGQEPGDEAKIAE
FCTLTYGVDFPMAAKIKVNGADAHPLWQWLKHRRRGLFGVAAIKWNFTKFLIGRNGQPIARYSPIKSPEQLEVHIVRALG
EEGGGNTH
>Mature_167_residues
SSIYTFTFTRLDGRPQALADWRGQVLLLVNVASRCGFTPQYAGLEMLWQRYRDAGLIVIGFPCDQFAGQEPGDEAKIAEF
CTLTYGVDFPMAAKIKVNGADAHPLWQWLKHRRRGLFGVAAIKWNFTKFLIGRNGQPIARYSPIKSPEQLEVHIVRALGE
EGGGNTH

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=153, Percent_Identity=45.7516339869281, Blast_Score=129, Evalue=2e-30,
Organism=Homo sapiens, GI90903240, Length=153, Percent_Identity=45.7516339869281, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=46.5648854961832, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI15618997, Length=155, Percent_Identity=37.4193548387097, Blast_Score=101, Evalue=3e-22,
Organism=Homo sapiens, GI192455698, Length=145, Percent_Identity=33.1034482758621, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI4557629, Length=145, Percent_Identity=35.1724137931034, Blast_Score=87, Evalue=8e-18,
Organism=Homo sapiens, GI41406084, Length=166, Percent_Identity=34.3373493975904, Blast_Score=83, Evalue=1e-16,
Organism=Homo sapiens, GI6006001, Length=179, Percent_Identity=31.2849162011173, Blast_Score=81, Evalue=4e-16,
Organism=Homo sapiens, GI33186887, Length=162, Percent_Identity=30.2469135802469, Blast_Score=72, Evalue=3e-13,
Organism=Escherichia coli, GI1788003, Length=167, Percent_Identity=43.1137724550898, Blast_Score=139, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI17506887, Length=163, Percent_Identity=44.7852760736196, Blast_Score=147, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=42.5, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71993584, Length=159, Percent_Identity=42.1383647798742, Blast_Score=131, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI193210707, Length=164, Percent_Identity=39.6341463414634, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17550320, Length=163, Percent_Identity=34.3558282208589, Blast_Score=102, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193209493, Length=163, Percent_Identity=33.1288343558282, Blast_Score=99, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71993573, Length=96, Percent_Identity=37.5, Blast_Score=73, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71999642, Length=76, Percent_Identity=38.1578947368421, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322228, Length=161, Percent_Identity=46.583850931677, Blast_Score=171, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6319721, Length=160, Percent_Identity=44.375, Blast_Score=167, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6322826, Length=151, Percent_Identity=41.7218543046358, Blast_Score=145, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24656777, Length=161, Percent_Identity=39.7515527950311, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI24656767, Length=161, Percent_Identity=39.7515527950311, Blast_Score=122, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24656772, Length=161, Percent_Identity=39.7515527950311, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI85726443, Length=160, Percent_Identity=37.5, Blast_Score=98, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 18826; Mature: 18695

Theoretical pI: Translated: 9.19; Mature: 9.19

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSIYTFTFTRLDGRPQALADWRGQVLLLVNVASRCGFTPQYAGLEMLWQRYRDAGLIVI
CCCEEEEEEEEECCCCHHHHCCCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHCCCCEEEE
GFPCDQFAGQEPGDEAKIAEFCTLTYGVDFPMAAKIKVNGADAHPLWQWLKHRRRGLFGV
ECCCHHHCCCCCCCCHHHHHHEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEE
AAIKWNFTKFLIGRNGQPIARYSPIKSPEQLEVHIVRALGEEGGGNTH
EEEEECCEEEEECCCCCCCCCCCCCCCCCHHHHHHEEECCCCCCCCCC
>Mature Secondary Structure 
SSIYTFTFTRLDGRPQALADWRGQVLLLVNVASRCGFTPQYAGLEMLWQRYRDAGLIVI
CCEEEEEEEEECCCCHHHHCCCCCEEEEEEEHHHCCCCCCHHHHHHHHHHHCCCCEEEE
GFPCDQFAGQEPGDEAKIAEFCTLTYGVDFPMAAKIKVNGADAHPLWQWLKHRRRGLFGV
ECCCHHHCCCCCCCCHHHHHHEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHCCCEEE
AAIKWNFTKFLIGRNGQPIARYSPIKSPEQLEVHIVRALGEEGGGNTH
EEEEECCEEEEECCCCCCCCCCCCCCCCCHHHHHHEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]