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The map label for this gene is cysH

Identifier: 182681303

GI number: 182681303

Start: 885183

End: 885896

Strand: Reverse

Name: cysH

Synonym: XfasM23_0750

Alternate gene names: 182681303

Gene position: 885896-885183 (Counterclockwise)

Preceding gene: 182681304

Following gene: 182681302

Centisome position: 34.94

GC content: 54.9

Gene sequence:

>714_bases
ATGACCGTACTTCCCGCCTTACCTCCTCTGGACGATCTGGAAACGCTCAACGTCCACCTAGAAACGCTGAGTGCTGAAAA
TCGCGTGTGCTGGGCACTGGAGCACGGTCCTGACCACCCTGCACTGTCTTCCAGCTTCGGCGCGCAATCGGCCGTCATGC
TGCATCTACTCACCCGGTTTGCACCGGATATTACGGTGATCCTGGTCGACACCGGCTATCTTTTCCCAGAAACCTACCGT
TTCGCCGACACGCTGACCGAACGACTCAAGCTCAATCTGAAGGTATACCAGCCGCTGCGTAGCGGCGCTTGGACGGAAGC
CCGTCATGGTCGACTATGGGAACAAGGGATCGACGGAATTAATCAATACAACACCCTGCACAAGGTCGAACCGATGCGCA
GGGCATTAGAGGAATTGCAAGTCGGCACCTGGTTTACCGGCCTACGTCGCGGACAATCCAGTACCCGTACCCAAACATCA
ATCGTGCAACGACGTGACGAGCGGTACAAAATCAGTCCAATTGCCGACTGGACCGACCGTGATATCTGGGAATACATGAA
ACACCATGATCTGCCCTATCACCCGCTTTGGGAACAGGGCTACGTTTCAATCGGTGACATTCACACGACACGCCCCTTGG
AACCAGACATGCGCGAGGAGGACACACGCTTCTTCGGATTCAAACGTGAGTGCGGGATTCACGAGAACATCTAA

Upstream 100 bases:

>100_bases
TTCCGAGCGAAGGCTTTGGCGATTTTCTACATCGCACCGGCATCATCGCACTTCCCCCATATCCCACCCACCGACACGTG
ATTTCCTCAACGCTGCAAGC

Downstream 100 bases:

>100_bases
GGCAGGTGTACATACCGCTACAACACTCTCGAGGATATACGGACATAGGCCTTCAGCCTTATTGTGTCTTCTCAAGACTG
AATGCGCATGAGCAACAGCA

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTVLPALPPLDDLETLNVHLETLSAENRVCWALEHGPDHPALSSSFGAQSAVMLHLLTRFAPDITVILVDTGYLFPETYR
FADTLTERLKLNLKVYQPLRSGAWTEARHGRLWEQGIDGINQYNTLHKVEPMRRALEELQVGTWFTGLRRGQSSTRTQTS
IVQRRDERYKISPIADWTDRDIWEYMKHHDLPYHPLWEQGYVSIGDIHTTRPLEPDMREEDTRFFGFKRECGIHENI

Sequences:

>Translated_237_residues
MTVLPALPPLDDLETLNVHLETLSAENRVCWALEHGPDHPALSSSFGAQSAVMLHLLTRFAPDITVILVDTGYLFPETYR
FADTLTERLKLNLKVYQPLRSGAWTEARHGRLWEQGIDGINQYNTLHKVEPMRRALEELQVGTWFTGLRRGQSSTRTQTS
IVQRRDERYKISPIADWTDRDIWEYMKHHDLPYHPLWEQGYVSIGDIHTTRPLEPDMREEDTRFFGFKRECGIHENI
>Mature_236_residues
TVLPALPPLDDLETLNVHLETLSAENRVCWALEHGPDHPALSSSFGAQSAVMLHLLTRFAPDITVILVDTGYLFPETYRF
ADTLTERLKLNLKVYQPLRSGAWTEARHGRLWEQGIDGINQYNTLHKVEPMRRALEELQVGTWFTGLRRGQSSTRTQTSI
VQRRDERYKISPIADWTDRDIWEYMKHHDLPYHPLWEQGYVSIGDIHTTRPLEPDMREEDTRFFGFKRECGIHENI

Specific function: Reduction of activated sulfate into sulfite

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily

Homologues:

Organism=Escherichia coli, GI1789121, Length=238, Percent_Identity=56.7226890756302, Blast_Score=288, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6325425, Length=220, Percent_Identity=31.8181818181818, Blast_Score=108, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CYSH_XYLF2 (B2IA30)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829463.1
- ProteinModelPortal:   B2IA30
- SMR:   B2IA30
- GeneID:   6202121
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0750
- HOGENOM:   HBG758022
- OMA:   QVNPSAK
- ProtClustDB:   PRK02090
- GO:   GO:0005737
- HAMAP:   MF_00063
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR011800
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- TIGRFAMs:   TIGR00434
- TIGRFAMs:   TIGR02057

Pfam domain/function: PF01507 PAPS_reduct

EC number: =1.8.4.8

Molecular weight: Translated: 27581; Mature: 27449

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLPALPPLDDLETLNVHLETLSAENRVCWALEHGPDHPALSSSFGAQSAVMLHLLTRF
CCCCCCCCCCCCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
APDITVILVDTGYLFPETYRFADTLTERLKLNLKVYQPLRSGAWTEARHGRLWEQGIDGI
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEECHHHCCCCCCHHCCCHHHHHHCHH
NQYNTLHKVEPMRRALEELQVGTWFTGLRRGQSSTRTQTSIVQRRDERYKISPIADWTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCH
DIWEYMKHHDLPYHPLWEQGYVSIGDIHTTRPLEPDMREEDTRFFGFKRECGIHENI
HHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHCCHHHCCCCCCC
>Mature Secondary Structure 
TVLPALPPLDDLETLNVHLETLSAENRVCWALEHGPDHPALSSSFGAQSAVMLHLLTRF
CCCCCCCCCCCCHHHEEEEEEECCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
APDITVILVDTGYLFPETYRFADTLTERLKLNLKVYQPLRSGAWTEARHGRLWEQGIDGI
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHEECHHHCCCCCCHHCCCHHHHHHCHH
NQYNTLHKVEPMRRALEELQVGTWFTGLRRGQSSTRTQTSIVQRRDERYKISPIADWTDR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCH
DIWEYMKHHDLPYHPLWEQGYVSIGDIHTTRPLEPDMREEDTRFFGFKRECGIHENI
HHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA