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The map label for this gene is trxB [H]

Identifier: 182681258

GI number: 182681258

Start: 828575

End: 829540

Strand: Reverse

Name: trxB [H]

Synonym: XfasM23_0703

Alternate gene names: 182681258

Gene position: 829540-828575 (Counterclockwise)

Preceding gene: 182681266

Following gene: 182681257

Centisome position: 32.71

GC content: 53.11

Gene sequence:

>966_bases
ATGAGCGATTATCCTGCCTCTGCCAAACACTCGCGCTTGTTGATCCTAGGCTCTGGCCCAGCTGGATGGACTGCCGCTGT
CTACGCCGCACGTGCAAACCTTCAACCAGTATTAATCACTGGCCTGCAACAGGGCGGACAATTGATGACCACCACCGAAG
TCGATAACTGGCCTGGTGACGCCCATGGCCTGATGGGACCGGACCTAATGGAACGGATGCAAGCCCATGCCGAACGCTTC
GAAACGGAAGTCATTTTCGACCAAATTTATAAAGCCGATCTCTCCACACGTCCATTCACCCTTTTTGGAGACAGCGGCAT
CTATACCTGCGATGGGTTGATCATCGCCACAGGTGCGAACGCCAAATACTTAGGCATCCCTTCCGAAGAGGCATTCAAAG
GTCGAGGGGTGTCGGCCTGTGCGACGTGTGACGGTTTTTTCTACCGTGACCAAGATGTAGCCGTGATAGGTGGTGGTAAC
ACAGCCGTCGAGGAGGCCTTATATCTGTCCAACATCGCCCGTAAGGTTTACTTAATACATCGCCGTGACAAACTGCGGGC
CGAAAAAATCATGCAAAACAAACTGTTCTCGAAAGCTGCAACCGGCAAAATAGAACTGATCTGGAACAACGCAGTCGAGG
AGGTACTCGGTAACGATGCTGGCGTCACTGGTGTACGGATCCGATCCACGCAAGACAGCAGCACGCGTGACATTGATGTC
CAAGGCCTCTTCGTGGCAATCGGACATCATCCCAATACCGATCTTTTCGCAGGCCAACTTGCAATGAACAACGGCTACCT
GCAAATACATTCAGGCACCGCAGGCAACGTCACCCAAACTTCCGTAGAGGGGGTATTCGCAGCAGGTGACGTTGCGGATC
AACACTACCGCCAAGCAATCACCTCAGCTGGATTTGGCTGCATGGCAGCTCTGGACGCGGAACGGTTCCTTGATAAAGGC
AACTGA

Upstream 100 bases:

>100_bases
GATTCACCGACAAAGGGGAACAATATCTATGACGCGAACCCAAGCTAGCAATCCGCTGCAATCTGTCGCAACTCTCAATT
AATTAAGTAAGCAAGTATAC

Downstream 100 bases:

>100_bases
ACCATTGGAGTACAACATCAGAAATATAAACAAACACCGCGAATCTCCATTGAGCATTTCACATTTTAAAACATCATGAG
GAACGGGTCACAAATCACTG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 321; Mature: 320

Protein sequence:

>321_residues
MSDYPASAKHSRLLILGSGPAGWTAAVYAARANLQPVLITGLQQGGQLMTTTEVDNWPGDAHGLMGPDLMERMQAHAERF
ETEVIFDQIYKADLSTRPFTLFGDSGIYTCDGLIIATGANAKYLGIPSEEAFKGRGVSACATCDGFFYRDQDVAVIGGGN
TAVEEALYLSNIARKVYLIHRRDKLRAEKIMQNKLFSKAATGKIELIWNNAVEEVLGNDAGVTGVRIRSTQDSSTRDIDV
QGLFVAIGHHPNTDLFAGQLAMNNGYLQIHSGTAGNVTQTSVEGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDKG
N

Sequences:

>Translated_321_residues
MSDYPASAKHSRLLILGSGPAGWTAAVYAARANLQPVLITGLQQGGQLMTTTEVDNWPGDAHGLMGPDLMERMQAHAERF
ETEVIFDQIYKADLSTRPFTLFGDSGIYTCDGLIIATGANAKYLGIPSEEAFKGRGVSACATCDGFFYRDQDVAVIGGGN
TAVEEALYLSNIARKVYLIHRRDKLRAEKIMQNKLFSKAATGKIELIWNNAVEEVLGNDAGVTGVRIRSTQDSSTRDIDV
QGLFVAIGHHPNTDLFAGQLAMNNGYLQIHSGTAGNVTQTSVEGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDKG
N
>Mature_320_residues
SDYPASAKHSRLLILGSGPAGWTAAVYAARANLQPVLITGLQQGGQLMTTTEVDNWPGDAHGLMGPDLMERMQAHAERFE
TEVIFDQIYKADLSTRPFTLFGDSGIYTCDGLIIATGANAKYLGIPSEEAFKGRGVSACATCDGFFYRDQDVAVIGGGNT
AVEEALYLSNIARKVYLIHRRDKLRAEKIMQNKLFSKAATGKIELIWNNAVEEVLGNDAGVTGVRIRSTQDSSTRDIDVQ
GLFVAIGHHPNTDLFAGQLAMNNGYLQIHSGTAGNVTQTSVEGVFAAGDVADQHYRQAITSAGFGCMAALDAERFLDKGN

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=313, Percent_Identity=71.2460063897764, Blast_Score=460, Evalue=1e-131,
Organism=Escherichia coli, GI87081763, Length=311, Percent_Identity=32.475884244373, Blast_Score=137, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=45.3125, Blast_Score=278, Evalue=9e-76,
Organism=Saccharomyces cerevisiae, GI6321898, Length=320, Percent_Identity=44.0625, Blast_Score=266, Evalue=3e-72,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34501; Mature: 34370

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYPASAKHSRLLILGSGPAGWTAAVYAARANLQPVLITGLQQGGQLMTTTEVDNWPGD
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCC
AHGLMGPDLMERMQAHAERFETEVIFDQIYKADLSTRPFTLFGDSGIYTCDGLIIATGAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECCEEEEECCC
AKYLGIPSEEAFKGRGVSACATCDGFFYRDQDVAVIGGGNTAVEEALYLSNIARKVYLIH
EEEECCCCHHHHCCCCCEEEEECCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHEEEEE
RRDKLRAEKIMQNKLFSKAATGKIELIWNNAVEEVLGNDAGVTGVRIRSTQDSSTRDIDV
CHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCEEEEECCCCCCCCEEEE
QGLFVAIGHHPNTDLFAGQLAMNNGYLQIHSGTAGNVTQTSVEGVFAAGDVADQHYRQAI
EEEEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCEEHHHCEEEEECCHHHHHHHHHH
TSAGFGCMAALDAERFLDKGN
HHCCCHHHHHHCHHHHHCCCC
>Mature Secondary Structure 
SDYPASAKHSRLLILGSGPAGWTAAVYAARANLQPVLITGLQQGGQLMTTTEVDNWPGD
CCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECCCCCCC
AHGLMGPDLMERMQAHAERFETEVIFDQIYKADLSTRPFTLFGDSGIYTCDGLIIATGAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEECCEEEEECCC
AKYLGIPSEEAFKGRGVSACATCDGFFYRDQDVAVIGGGNTAVEEALYLSNIARKVYLIH
EEEECCCCHHHHCCCCCEEEEECCCCEEECCCEEEEECCCHHHHHHHHHHHHHHHEEEEE
RRDKLRAEKIMQNKLFSKAATGKIELIWNNAVEEVLGNDAGVTGVRIRSTQDSSTRDIDV
CHHHHHHHHHHHHHHHHHHCCCEEEEEECHHHHHHHCCCCCCCEEEEECCCCCCCCEEEE
QGLFVAIGHHPNTDLFAGQLAMNNGYLQIHSGTAGNVTQTSVEGVFAAGDVADQHYRQAI
EEEEEEECCCCCCCEEEEEEEECCCEEEEECCCCCCCEEHHHCEEEEECCHHHHHHHHHH
TSAGFGCMAALDAERFLDKGN
HHCCCHHHHHHCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]