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The map label for this gene is hup [H]

Identifier: 182681031

GI number: 182681031

Start: 569437

End: 569721

Strand: Direct

Name: hup [H]

Synonym: XfasM23_0470

Alternate gene names: 182681031

Gene position: 569437-569721 (Clockwise)

Preceding gene: 182681030

Following gene: 182681032

Centisome position: 22.46

GC content: 48.77

Gene sequence:

>285_bases
ATGAATAAAACCGAATTGATTGATGGTGTTGCTGCTGCTGCTAATTTGTCCAAGGTTGAGGCGGGTCGTGCTATTGATGC
CGTCGTTAATGAAATTACTGAGGCCCTCAAAGAGGGTGATTCCGTTACGTTGGTAGGGTTCGGTACTTTCCAGGTGCGTC
AGCGTGCTGAGCGTCCTGGCCGCAATCCGAAGACTGGTGAACCTATCATGATCGCTGCATCAAATAACCCTTCATTCAAG
CCTGGTAAAGCACTAAAAGATGCCGTAAAATCCTCCGCTGGCTAG

Upstream 100 bases:

>100_bases
TGCGCTATGCTAATCAGGTACTTGGTTTAAATTCCTTGCCTCATGAGGCAAAAGACCGATTTTTGATTCTGCGGCTCAAT
GCCGTAATGGGAGTTTTTAG

Downstream 100 bases:

>100_bases
GGGGTGCTTAGCTCAGCGGTAGAGCGTCTCCCTTACAAGGAGAGGGCCGGGGGTTCGAAACCCTCAGCACCCACCAAAGC
ATTAATGATTAAAGTTTTGT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 94; Mature: 94

Protein sequence:

>94_residues
MNKTELIDGVAAAANLSKVEAGRAIDAVVNEITEALKEGDSVTLVGFGTFQVRQRAERPGRNPKTGEPIMIAASNNPSFK
PGKALKDAVKSSAG

Sequences:

>Translated_94_residues
MNKTELIDGVAAAANLSKVEAGRAIDAVVNEITEALKEGDSVTLVGFGTFQVRQRAERPGRNPKTGEPIMIAASNNPSFK
PGKALKDAVKSSAG
>Mature_94_residues
MNKTELIDGVAAAANLSKVEAGRAIDAVVNEITEALKEGDSVTLVGFGTFQVRQRAERPGRNPKTGEPIMIAASNNPSFK
PGKALKDAVKSSAG

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=89, Percent_Identity=64.0449438202247, Blast_Score=121, Evalue=7e-30,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=63.3333333333333, Blast_Score=115, Evalue=6e-28,
Organism=Escherichia coli, GI1788005, Length=93, Percent_Identity=39.7849462365591, Blast_Score=74, Evalue=1e-15,
Organism=Escherichia coli, GI1787141, Length=90, Percent_Identity=38.8888888888889, Blast_Score=66, Evalue=4e-13,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9780; Mature: 9780

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKTELIDGVAAAANLSKVEAGRAIDAVVNEITEALKEGDSVTLVGFGTFQVRQRAERPG
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCC
RNPKTGEPIMIAASNNPSFKPGKALKDAVKSSAG
CCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNKTELIDGVAAAANLSKVEAGRAIDAVVNEITEALKEGDSVTLVGFGTFQVRQRAERPG
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCC
RNPKTGEPIMIAASNNPSFKPGKALKDAVKSSAG
CCCCCCCCEEEEECCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]