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The map label for this gene is ppiD [H]

Identifier: 182681032

GI number: 182681032

Start: 570292

End: 572259

Strand: Direct

Name: ppiD [H]

Synonym: XfasM23_0471

Alternate gene names: 182681032

Gene position: 570292-572259 (Clockwise)

Preceding gene: 182681031

Following gene: 182681033

Centisome position: 22.49

GC content: 50.2

Gene sequence:

>1968_bases
ATGCTGCAAAAACTCCGTGAAAAAACATCTGGATGGATTGCGACTGCTATCATCGGATTATTGGTCATCCCTTTTCTGTT
TGTGATCGACGTTCGTTACATAGGGGTAGGGGGGAAGGACGATGTAGCGCAGTTACAGGCTTCGCCGACTTGGTGGAAGT
CTGCACCTGCTTTTTGGCCAATATCTTTATTGTGGCAGCGTCAAGGGATTAGCAAGCAAGAGTTCCAGAGCCGCTTCGAT
CAGGCGCGCCTGCAGCAGCGTGCTCAGCAGGGCGAAGGCTTCGATGCACGCGAGTTCGAGACCCTCAGTAACAAGCGCAA
GCTGTTAGATCAGTTAATCGAAGAGCATGTGATGCGTTTAGTGGCTGAGGGCGCGGGAGTGGTGATCAGTGATGAGGCCG
TGCGTACCATTATTGCTAACGATCAGCGTTTCCAGGTTAAAGGAAAGTTCAATCAAGATCGCTATCGCCTGCTGTTGGCT
CAGGAACCGACGATGCGTACCCCGCAGATGTACGAGAGCTATGTACGCAGCATGATGCAGCTATCTATGATTCCCAGCGC
GATTTTTGATTCTGGGTTTGTACCGAACACCGAGTTGGAGCGAATACTCGCGTTACTCGGCCAGACTCGCAATGCTGAGC
TCGTCACTTTACCGGCGTTGAAGCTTGATACGGCTGAGATTAGCGATATGCAGATCAAAGAATGGTATGCCGTTCATAGG
GATGATTTCCGTCAGCCGGAGACACTTTCGTTCGAATATGTTGATTTGGATGCCGCTCACTTACCCAGGCCGACGCCTAG
TGAGGCTATGTTGCGTAAACGCTACGATGCCCAGCAACGCGGGGAGGCTCAAAATGAGCAACGTAAGGCTGCGCATATTT
TAATTACTGCGGGTGCTGATGCTGCTTCACAAAAAGTAGCCGAGGCTAAGGCTGCCAAACTTGTTGAGGAAGCCCGCAAA
CCCGGTGCTGATTTTGCTGCGCTGGCTCGCATTAACTCACAGGATCCTGGCTCTAAAGATGCTGGTGGTGACTTGGGTTG
GGTGCAGAGAGGAATGATGGTTAAGCCGTTTGAGGATGCACTCTTTGCAATGAAAGTGGGTGAAGTGGTCGGCCCTATCA
AAACAGAATTTGGTAATCACGTGATCAAACTGGAAGAAATTAAGGCTGCTAAGCAATTACCGTTTGAAGCAGTACGGGAT
CAGCTTGCTGCAGAACAAACCAAGGAGGACATTGATAAGGCATTCAACGACGTTACAGGAAAACTGATGGACCTTTTAGT
CAAAAATCCGACTGATCTTTCTTCCGCGTCCGAACAATTGGGGCTGCCATTGCGCAAACTTGGCCCTTTGTCACGTCGTG
ATGCTGTTGGTATTGCTGCTAATCCTGCAGTGCAGCGAGTGTTGTTCAACCACGATTTTATCCAGGAGGGTAAAGTTAGC
GATCCCATTCAGATTAATCCGAATCACAGCGTGGTATTACGCGTGATTGCGCATACCACTGAGCAGCAACTGCCGTTGGA
TAAGGTGCGTGAGCAAGTTGTTGCTGCGGTGCGCGCTGATCGTGCGGAAAAGGATGAGGCCTCTGCAGCGGATGCACTGG
TAGCACGGTTGCAGAAGGGAGAAACCTTAGAAGAGGTCGCAAAAGCTGAGAAATTGCAGATTACACCTCTTACCGGTTTG
CAACGTACTGCACAGGTTCCGGCGTTTGCGGCTACCCGTGCAATTTTTTCGGCATTATCTCCGGTTGCGGGTAAGCCGAC
GGTTGGTAAAGTGCGTTTGGACGATGGTCGCTATGCAGTGTTTACGGTTACTCGAGTGATCCCTGGTGATCTAACGAAAC
TCCCTGAAGAGCAGAAAGCGATGCTTAGACAACAGCTTGATCAGATTGAGGGAACGCTAGCAGTCCATGCTTACGTTGAT
ATGATGCGTAAGCGCTTCAAAGTGACCATTCACAAGTCGCAATTGTAA

Upstream 100 bases:

>100_bases
CTAAAGCTGCCATCCGTGTCTTTACGTTAAACAATTGGCGCCGCTTCAAGCAGGTTAAAATCTAGAATATCTCCTCAGAT
CTTACGATTCTCAAATACTA

Downstream 100 bases:

>100_bases
CGTGATCGTAAGCAACCTCTCGTTGTTTGATTGGTACAAGAGACATAGGAAGTTGCTAGAAAGTCATTCTTATACAGAGT
GTGCAACTTTGCTTGCCGTT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MLQKLREKTSGWIATAIIGLLVIPFLFVIDVRYIGVGGKDDVAQLQASPTWWKSAPAFWPISLLWQRQGISKQEFQSRFD
QARLQQRAQQGEGFDAREFETLSNKRKLLDQLIEEHVMRLVAEGAGVVISDEAVRTIIANDQRFQVKGKFNQDRYRLLLA
QEPTMRTPQMYESYVRSMMQLSMIPSAIFDSGFVPNTELERILALLGQTRNAELVTLPALKLDTAEISDMQIKEWYAVHR
DDFRQPETLSFEYVDLDAAHLPRPTPSEAMLRKRYDAQQRGEAQNEQRKAAHILITAGADAASQKVAEAKAAKLVEEARK
PGADFAALARINSQDPGSKDAGGDLGWVQRGMMVKPFEDALFAMKVGEVVGPIKTEFGNHVIKLEEIKAAKQLPFEAVRD
QLAAEQTKEDIDKAFNDVTGKLMDLLVKNPTDLSSASEQLGLPLRKLGPLSRRDAVGIAANPAVQRVLFNHDFIQEGKVS
DPIQINPNHSVVLRVIAHTTEQQLPLDKVREQVVAAVRADRAEKDEASAADALVARLQKGETLEEVAKAEKLQITPLTGL
QRTAQVPAFAATRAIFSALSPVAGKPTVGKVRLDDGRYAVFTVTRVIPGDLTKLPEEQKAMLRQQLDQIEGTLAVHAYVD
MMRKRFKVTIHKSQL

Sequences:

>Translated_655_residues
MLQKLREKTSGWIATAIIGLLVIPFLFVIDVRYIGVGGKDDVAQLQASPTWWKSAPAFWPISLLWQRQGISKQEFQSRFD
QARLQQRAQQGEGFDAREFETLSNKRKLLDQLIEEHVMRLVAEGAGVVISDEAVRTIIANDQRFQVKGKFNQDRYRLLLA
QEPTMRTPQMYESYVRSMMQLSMIPSAIFDSGFVPNTELERILALLGQTRNAELVTLPALKLDTAEISDMQIKEWYAVHR
DDFRQPETLSFEYVDLDAAHLPRPTPSEAMLRKRYDAQQRGEAQNEQRKAAHILITAGADAASQKVAEAKAAKLVEEARK
PGADFAALARINSQDPGSKDAGGDLGWVQRGMMVKPFEDALFAMKVGEVVGPIKTEFGNHVIKLEEIKAAKQLPFEAVRD
QLAAEQTKEDIDKAFNDVTGKLMDLLVKNPTDLSSASEQLGLPLRKLGPLSRRDAVGIAANPAVQRVLFNHDFIQEGKVS
DPIQINPNHSVVLRVIAHTTEQQLPLDKVREQVVAAVRADRAEKDEASAADALVARLQKGETLEEVAKAEKLQITPLTGL
QRTAQVPAFAATRAIFSALSPVAGKPTVGKVRLDDGRYAVFTVTRVIPGDLTKLPEEQKAMLRQQLDQIEGTLAVHAYVD
MMRKRFKVTIHKSQL
>Mature_655_residues
MLQKLREKTSGWIATAIIGLLVIPFLFVIDVRYIGVGGKDDVAQLQASPTWWKSAPAFWPISLLWQRQGISKQEFQSRFD
QARLQQRAQQGEGFDAREFETLSNKRKLLDQLIEEHVMRLVAEGAGVVISDEAVRTIIANDQRFQVKGKFNQDRYRLLLA
QEPTMRTPQMYESYVRSMMQLSMIPSAIFDSGFVPNTELERILALLGQTRNAELVTLPALKLDTAEISDMQIKEWYAVHR
DDFRQPETLSFEYVDLDAAHLPRPTPSEAMLRKRYDAQQRGEAQNEQRKAAHILITAGADAASQKVAEAKAAKLVEEARK
PGADFAALARINSQDPGSKDAGGDLGWVQRGMMVKPFEDALFAMKVGEVVGPIKTEFGNHVIKLEEIKAAKQLPFEAVRD
QLAAEQTKEDIDKAFNDVTGKLMDLLVKNPTDLSSASEQLGLPLRKLGPLSRRDAVGIAANPAVQRVLFNHDFIQEGKVS
DPIQINPNHSVVLRVIAHTTEQQLPLDKVREQVVAAVRADRAEKDEASAADALVARLQKGETLEEVAKAEKLQITPLTGL
QRTAQVPAFAATRAIFSALSPVAGKPTVGKVRLDDGRYAVFTVTRVIPGDLTKLPEEQKAMLRQQLDQIEGTLAVHAYVD
MMRKRFKVTIHKSQL

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=658, Percent_Identity=26.1398176291793, Blast_Score=184, Evalue=2e-47,
Organism=Escherichia coli, GI1786238, Length=108, Percent_Identity=34.2592592592593, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 72986; Mature: 72986

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQKLREKTSGWIATAIIGLLVIPFLFVIDVRYIGVGGKDDVAQLQASPTWWKSAPAFWP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCH
ISLLWQRQGISKQEFQSRFDQARLQQRAQQGEGFDAREFETLSNKRKLLDQLIEEHVMRL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VAEGAGVVISDEAVRTIIANDQRFQVKGKFNQDRYRLLLAQEPTMRTPQMYESYVRSMMQ
HHCCCCEEEEHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LSMIPSAIFDSGFVPNTELERILALLGQTRNAELVTLPALKLDTAEISDMQIKEWYAVHR
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEECCCCCCCHHHHHHHHHHH
DDFRQPETLSFEYVDLDAAHLPRPTPSEAMLRKRYDAQQRGEAQNEQRKAAHILITAGAD
HCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHCHHHHCCHHHHHHCEEEEEEECCCC
AASQKVAEAKAAKLVEEARKPGADFAALARINSQDPGSKDAGGDLGWVQRGMMVKPFEDA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCHHHH
LFAMKVGEVVGPIKTEFGNHVIKLEEIKAAKQLPFEAVRDQLAAEQTKEDIDKAFNDVTG
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KLMDLLVKNPTDLSSASEQLGLPLRKLGPLSRRDAVGIAANPAVQRVLFNHDFIQEGKVS
HHHHHHHCCCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHCCCCCC
DPIQINPNHSVVLRVIAHTTEQQLPLDKVREQVVAAVRADRAEKDEASAADALVARLQKG
CCEEECCCHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
ETLEEVAKAEKLQITPLTGLQRTAQVPAFAATRAIFSALSPVAGKPTVGKVRLDDGRYAV
CHHHHHHHHHCEEECCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEE
FTVTRVIPGDLTKLPEEQKAMLRQQLDQIEGTLAVHAYVDMMRKRFKVTIHKSQL
EEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC
>Mature Secondary Structure
MLQKLREKTSGWIATAIIGLLVIPFLFVIDVRYIGVGGKDDVAQLQASPTWWKSAPAFWP
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCCCCCCCCCCCH
ISLLWQRQGISKQEFQSRFDQARLQQRAQQGEGFDAREFETLSNKRKLLDQLIEEHVMRL
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
VAEGAGVVISDEAVRTIIANDQRFQVKGKFNQDRYRLLLAQEPTMRTPQMYESYVRSMMQ
HHCCCCEEEEHHHHHHHHCCCCEEEEECCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHH
LSMIPSAIFDSGFVPNTELERILALLGQTRNAELVTLPALKLDTAEISDMQIKEWYAVHR
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEECCCCCCCHHHHHHHHHHH
DDFRQPETLSFEYVDLDAAHLPRPTPSEAMLRKRYDAQQRGEAQNEQRKAAHILITAGAD
HCCCCCCCCEEEEEECCHHHCCCCCCHHHHHHHHHCHHHHCCHHHHHHCEEEEEEECCCC
AASQKVAEAKAAKLVEEARKPGADFAALARINSQDPGSKDAGGDLGWVQRGMMVKPFEDA
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCHHHH
LFAMKVGEVVGPIKTEFGNHVIKLEEIKAAKQLPFEAVRDQLAAEQTKEDIDKAFNDVTG
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KLMDLLVKNPTDLSSASEQLGLPLRKLGPLSRRDAVGIAANPAVQRVLFNHDFIQEGKVS
HHHHHHHCCCCCHHHHHHHHCCCHHHCCCCCCCCCCCCCCCHHHHHHHHCCCHHCCCCCC
DPIQINPNHSVVLRVIAHTTEQQLPLDKVREQVVAAVRADRAEKDEASAADALVARLQKG
CCEEECCCHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCC
ETLEEVAKAEKLQITPLTGLQRTAQVPAFAATRAIFSALSPVAGKPTVGKVRLDDGRYAV
CHHHHHHHHHCEEECCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCEEEECCCCEEE
FTVTRVIPGDLTKLPEEQKAMLRQQLDQIEGTLAVHAYVDMMRKRFKVTIHKSQL
EEEEECCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]