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The map label for this gene is nudG [H]

Identifier: 182680967

GI number: 182680967

Start: 506775

End: 507737

Strand: Direct

Name: nudG [H]

Synonym: XfasM23_0405

Alternate gene names: 182680967

Gene position: 506775-507737 (Clockwise)

Preceding gene: 182680966

Following gene: 182680970

Centisome position: 19.99

GC content: 58.98

Gene sequence:

>963_bases
ATGACTGATTCTTTGCGATCTATTCATGTTGTGGCAGCTGTGATTGCTGATGTGCGAGGACGCTTGCTGCTGAGTAGGCG
TACCGAGAACAGCGATATGCCTGGCTTGTGGGAATTTCCAGGGGGAAAGCGTGAGTCTGGTGAGACATCCGAGCAGGCGT
TGGCCCGCGAGTTGTATGAGGAACTTGGGATCAGCGCTGACGTTGGCGAGTGGTTGATGGAGGTGCCGCAGTTGTATCCG
GGTAAACGTCTGCGTCTGGAGGTGAGGCGGGTGCGTGCTTGGAAGGGGGGGCTGCGGGGACGTGAGGGACAGGCGTTGAC
GTGGGTCGAACCCGATAAATTGTTGCGTTATTCGATGCCGCCGGCTGATCAGCCGGTCGTGGGGATGTTGCGTCAACCAG
ACCGTTATTTGGTGACACCTGAGCCTGGGGAGCAGGATGCTGAGTGGTTGGATGCAGTGGAGCATGCGTATCGGCTTGGC
ATTGAGCGGATCCAGCTGCGCATGCGTCAACACGATCCGGTGCGTTGGTCGGGGTTGGTGCGCCAAGCAGTGCAACGTCG
TGGCCGTGCCCATGTGGAAGTGTTGCTGAATCGCGATATTGCTTTGGCCGAGGCCTTGGGTATCGGGGTGCATTTGGGGG
CTGAACAGTTGGCTGTGTTGGATGCGCGTCCGTTGCCGGTTGGGTTGCCGGTCGGTGCGTCGTGTCATTGCCTGGCCGAT
TTGTGCCATGCCCAGCGCATTGGGTGTGATTTTGCGGTGCTCGGCCCGGTGTTACCGACGGAGAGTCATCCTGGTGCAGT
GACATTGGGGTGGGAGAGGTTTGAGCAGTTGCGCGAGCAGGTTGCATTGCCAATCTATGCGATCGGTGGGATGTGCGCTG
ATCAGGTCAAGGAAGCACGGCGTCATGGTGCGCAAGGGATTGCTGCCATGCGTGGTTTGTGGCCGGGGGGAGCGAAGCAA
TAA

Upstream 100 bases:

>100_bases
GGAGATGGATGTCCTGGGATACCCTGCGATGTGTGAATCAAGTCGTATGTATGAGTCATTCTGTTGCATGGGATGACGAG
ATATCGGCAAGCTTGCGGAT

Downstream 100 bases:

>100_bases
GGCGTGGCTACTGTTGCTGTATGTGATGCAGTGGTGGGCGTGCTGTGGTGGCTTCAATAGCCTAAGCGTTGCAGCACTTG
GGTGCTTGGTTTGGCTAGGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MTDSLRSIHVVAAVIADVRGRLLLSRRTENSDMPGLWEFPGGKRESGETSEQALARELYEELGISADVGEWLMEVPQLYP
GKRLRLEVRRVRAWKGGLRGREGQALTWVEPDKLLRYSMPPADQPVVGMLRQPDRYLVTPEPGEQDAEWLDAVEHAYRLG
IERIQLRMRQHDPVRWSGLVRQAVQRRGRAHVEVLLNRDIALAEALGIGVHLGAEQLAVLDARPLPVGLPVGASCHCLAD
LCHAQRIGCDFAVLGPVLPTESHPGAVTLGWERFEQLREQVALPIYAIGGMCADQVKEARRHGAQGIAAMRGLWPGGAKQ

Sequences:

>Translated_320_residues
MTDSLRSIHVVAAVIADVRGRLLLSRRTENSDMPGLWEFPGGKRESGETSEQALARELYEELGISADVGEWLMEVPQLYP
GKRLRLEVRRVRAWKGGLRGREGQALTWVEPDKLLRYSMPPADQPVVGMLRQPDRYLVTPEPGEQDAEWLDAVEHAYRLG
IERIQLRMRQHDPVRWSGLVRQAVQRRGRAHVEVLLNRDIALAEALGIGVHLGAEQLAVLDARPLPVGLPVGASCHCLAD
LCHAQRIGCDFAVLGPVLPTESHPGAVTLGWERFEQLREQVALPIYAIGGMCADQVKEARRHGAQGIAAMRGLWPGGAKQ
>Mature_319_residues
TDSLRSIHVVAAVIADVRGRLLLSRRTENSDMPGLWEFPGGKRESGETSEQALARELYEELGISADVGEWLMEVPQLYPG
KRLRLEVRRVRAWKGGLRGREGQALTWVEPDKLLRYSMPPADQPVVGMLRQPDRYLVTPEPGEQDAEWLDAVEHAYRLGI
ERIQLRMRQHDPVRWSGLVRQAVQRRGRAHVEVLLNRDIALAEALGIGVHLGAEQLAVLDARPLPVGLPVGASCHCLADL
CHAQRIGCDFAVLGPVLPTESHPGAVTLGWERFEQLREQVALPIYAIGGMCADQVKEARRHGAQGIAAMRGLWPGGAKQ

Specific function: Specific for pyrimidine substrates. Acts on 5-methyl- dCTP, CTP and dCTP in decreasing order [H]

COG id: COG0352

COG function: function code H; Thiamine monophosphate synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Escherichia coli, GI1788056, Length=123, Percent_Identity=43.9024390243902, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1786288, Length=128, Percent_Identity=32.03125, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: 3.6.1.-; 2.5.1.3

Molecular weight: Translated: 35468; Mature: 35337

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSLRSIHVVAAVIADVRGRLLLSRRTENSDMPGLWEFPGGKRESGETSEQALARELYE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ELGISADVGEWLMEVPQLYPGKRLRLEVRRVRAWKGGLRGREGQALTWVEPDKLLRYSMP
HHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHEECCC
PADQPVVGMLRQPDRYLVTPEPGEQDAEWLDAVEHAYRLGIERIQLRMRQHDPVRWSGLV
CCCCCHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RQAVQRRGRAHVEVLLNRDIALAEALGIGVHLGAEQLAVLDARPLPVGLPVGASCHCLAD
HHHHHHCCCCEEEHHHCCCHHHHHHHHCCEECCHHHHHHCCCCCCCCCCCCCCCHHHHHH
LCHAQRIGCDFAVLGPVLPTESHPGAVTLGWERFEQLREQVALPIYAIGGMCADQVKEAR
HHHHHHHCCCHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHCCCHHHHCCCCHHHHHHHH
RHGAQGIAAMRGLWPGGAKQ
HHCHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TDSLRSIHVVAAVIADVRGRLLLSRRTENSDMPGLWEFPGGKRESGETSEQALARELYE
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ELGISADVGEWLMEVPQLYPGKRLRLEVRRVRAWKGGLRGREGQALTWVEPDKLLRYSMP
HHCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEECHHHHHEECCC
PADQPVVGMLRQPDRYLVTPEPGEQDAEWLDAVEHAYRLGIERIQLRMRQHDPVRWSGLV
CCCCCHHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
RQAVQRRGRAHVEVLLNRDIALAEALGIGVHLGAEQLAVLDARPLPVGLPVGASCHCLAD
HHHHHHCCCCEEEHHHCCCHHHHHHHHCCEECCHHHHHHCCCCCCCCCCCCCCCHHHHHH
LCHAQRIGCDFAVLGPVLPTESHPGAVTLGWERFEQLREQVALPIYAIGGMCADQVKEAR
HHHHHHHCCCHHHHCCCCCCCCCCCEEEECHHHHHHHHHHHCCCHHHHCCCCHHHHHHHH
RHGAQGIAAMRGLWPGGAKQ
HHCHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe; Mn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 11053429 [H]