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The map label for this gene is cdsA [H]

Identifier: 182680887

GI number: 182680887

Start: 422745

End: 423599

Strand: Reverse

Name: cdsA [H]

Synonym: XfasM23_0325

Alternate gene names: 182680887

Gene position: 423599-422745 (Counterclockwise)

Preceding gene: 182680888

Following gene: 182680886

Centisome position: 16.71

GC content: 53.22

Gene sequence:

>855_bases
ATGACCCGAACCCGTGTCATTGCCGCGCTGGTCATGGCACCCGTCGCAATGTGTTCGATCCTGTTTTTACCAACGGCCTG
GTTAGCCTCATTGACAGCAATCATCTTCCTATGGGGCTTATGGGAATGGATGAAGCTGTCCCAGGTAGAGGACACCTTGG
TACGCACCGTGCTGCTGACACTGAACCTGCTTCTCATGGTGTTATTGGTTTGGGTTTCAGCTCACTCACTGGTGCTGTTT
CAGATTGCCACGCTCATTGGTATCGCCTGGTGGATCCTAGCATTGTTATGGCTACGCTTCCTCGGATTTTGTGCCGACCC
TAACCAACGCACCGCAAAGATAGTCAAAGTCACCGCAGGCACGTTAGCGGTGATTCCAGCGTGGTCTGCACTGGTCCTAC
TCCACTCAGGTGATAAGCCTGGCTCAACATTTCCAGAGAGCTTACATGCCCACCTGTGGCTGCTAACGGCTCAGATAATG
ATATGGGCCGCTGACTCCGGAGCGTATTTTTCTGGTCGCCTCTTTGGTAAACACAAACTGGCACCGCAGATCAGTCCCAA
CAAAACTGTAGAAGGCCTCCTCGGCGGCATACTCACTGGATTGGCAGTAGCGGCTGGTTTTGGTCTATTGAATGGCGTAA
CCATGGCCCAGTTCCCATCACTATTGCTCGTTTCATTCGTGGCAATCTTGGCTTCGGTGATCGGCGATTTGTTCGAAAGC
CTGCTTAAGCGCCACGCCGGCATCAAAGATTCCGGCAGTATGATTCCAGGCCACGGTGGCGTTCTCGATCGTATCGATAG
CACGCTCGCCGCACTCCCCGTGTTCGCACTGGGAAAAGACATCTTCGGTTTCTGA

Upstream 100 bases:

>100_bases
CCGTATTGCAGCAAGCGTTGGACGACTACGCCAGCCGGGAGCGTCGCTTCGGTCTAACAAATGCACAAATCGCCAGCCGG
GGGAAAGGAAGCATACCCGC

Downstream 100 bases:

>100_bases
GCATGACTAAACCGATCCGCAACGTCGCCGTACTCGGTGCCACTGGCTCAATTGGGGCAGCAGCACTGGATGTGCTCGCA
CGCCACCCCAGACAGTTCCA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MTRTRVIAALVMAPVAMCSILFLPTAWLASLTAIIFLWGLWEWMKLSQVEDTLVRTVLLTLNLLLMVLLVWVSAHSLVLF
QIATLIGIAWWILALLWLRFLGFCADPNQRTAKIVKVTAGTLAVIPAWSALVLLHSGDKPGSTFPESLHAHLWLLTAQIM
IWAADSGAYFSGRLFGKHKLAPQISPNKTVEGLLGGILTGLAVAAGFGLLNGVTMAQFPSLLLVSFVAILASVIGDLFES
LLKRHAGIKDSGSMIPGHGGVLDRIDSTLAALPVFALGKDIFGF

Sequences:

>Translated_284_residues
MTRTRVIAALVMAPVAMCSILFLPTAWLASLTAIIFLWGLWEWMKLSQVEDTLVRTVLLTLNLLLMVLLVWVSAHSLVLF
QIATLIGIAWWILALLWLRFLGFCADPNQRTAKIVKVTAGTLAVIPAWSALVLLHSGDKPGSTFPESLHAHLWLLTAQIM
IWAADSGAYFSGRLFGKHKLAPQISPNKTVEGLLGGILTGLAVAAGFGLLNGVTMAQFPSLLLVSFVAILASVIGDLFES
LLKRHAGIKDSGSMIPGHGGVLDRIDSTLAALPVFALGKDIFGF
>Mature_283_residues
TRTRVIAALVMAPVAMCSILFLPTAWLASLTAIIFLWGLWEWMKLSQVEDTLVRTVLLTLNLLLMVLLVWVSAHSLVLFQ
IATLIGIAWWILALLWLRFLGFCADPNQRTAKIVKVTAGTLAVIPAWSALVLLHSGDKPGSTFPESLHAHLWLLTAQIMI
WAADSGAYFSGRLFGKHKLAPQISPNKTVEGLLGGILTGLAVAAGFGLLNGVTMAQFPSLLLVSFVAILASVIGDLFESL
LKRHAGIKDSGSMIPGHGGVLDRIDSTLAALPVFALGKDIFGF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=281, Percent_Identity=39.8576512455516, Blast_Score=175, Evalue=3e-45,
Organism=Escherichia coli, GI1787677, Length=114, Percent_Identity=40.3508771929825, Blast_Score=86, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30576; Mature: 30445

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRTRVIAALVMAPVAMCSILFLPTAWLASLTAIIFLWGLWEWMKLSQVEDTLVRTVLLT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLLLMVLLVWVSAHSLVLFQIATLIGIAWWILALLWLRFLGFCADPNQRTAKIVKVTAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECC
TLAVIPAWSALVLLHSGDKPGSTFPESLHAHLWLLTAQIMIWAADSGAYFSGRLFGKHKL
HHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCEEECEECCCCCC
APQISPNKTVEGLLGGILTGLAVAAGFGLLNGVTMAQFPSLLLVSFVAILASVIGDLFES
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKRHAGIKDSGSMIPGHGGVLDRIDSTLAALPVFALGKDIFGF
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TRTRVIAALVMAPVAMCSILFLPTAWLASLTAIIFLWGLWEWMKLSQVEDTLVRTVLLT
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLLLMVLLVWVSAHSLVLFQIATLIGIAWWILALLWLRFLGFCADPNQRTAKIVKVTAG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEECC
TLAVIPAWSALVLLHSGDKPGSTFPESLHAHLWLLTAQIMIWAADSGAYFSGRLFGKHKL
HHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCEEECEECCCCCC
APQISPNKTVEGLLGGILTGLAVAAGFGLLNGVTMAQFPSLLLVSFVAILASVIGDLFES
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKRHAGIKDSGSMIPGHGGVLDRIDSTLAALPVFALGKDIFGF
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]